Chlorogentisylquinone, a new neutral sphingomyelinase inhibitor, produced by a marine fungus

Journal of Antibiotics

Volumn 54, Issue 11, 2001, Pages 882-889

  Uchida, R ^a   Tomoda, H ^a   Arai, M ^a   Omura, S ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 13; CHLOROGENTISYLQUINONE; ENZYME INHIBITOR; HYDROGEN; SEPHADEX; SILICA GEL; SOLVENT; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; ENZYME ACTIVITY; FUNGUS; FUNGUS CULTURE; GEL CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; MARINE ENVIRONMENT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

EID: 0035210919     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.54.882     Document Type: Article

References (19)

1. Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation
2. Ceramide stimulates a cytosolic protein phosphatase
3. The sphingomyelin cycle and the second messenger function of ceramide
4. Sphingomyelinases in cell regulation
5. The role of sphingolipids in the process of signal transduction
6. Signal transduction of stress via ceramide
7. Regulation of ceramide production and apoptosis
8. The role of ceramide in cell signaling
9. Signalling sphingomyelinase: Which, where, how and why?
10. Altenusin, a specific neutral sphingomyelinase inhibitor, produced by Penicillium sp. FO-7436
11. Über die isolierung eines chinhydrons von gentisinalkohl und oxymethyl-p-benzochinon (gentisin-chinon) aus dem kulturfiltract von Penicillium urticae Bainier
12. Characterization of the neutral pH-optimum sphingomyelinase from rat brain: Inhibition by copper II and ganglioside GM3
13. Acid sphingomyelinase from human urine: Purification and characterization
14. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity
15. Hypervalent iodine oxidation of p-alkoxy- and related phenols: A facile and effect synthesis of p-quinones
16. Scyphostatin, a neutral sphingomyelinase inhibitor from a discomycete, Trichopeziza mollissima: Taxonomy of the producing organism, fermentation, isolation, and physico-chemical properties
17. Biological activities of scyphostatin, a neutral sphingomyelinase inhibitor from a discomycete, Trichopeziza mollissima
18. F-11334s, new inhibitors of membrane-bound neutral sphingomyelinase
19. Naturally occurring quinones