Synthesis and biochemical investigation of scyphostatin analogues as inhibitors of neutral sphingomyelinase

Bioorganic and Medicinal Chemistry

Volumn 9, Issue 11, 2001, Pages 2901-2904

  Arenz, Christoph ^a   Gartner, Michael ^a   Wascholowski, Veit ^a   Giannis, Athanassios ^a  

^a UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DECANOIC ACID [1 (8 OXO 1 OXASPIRO[2.5]OCTA 4,6 DIENE 5 YLCARBAMOYL)ETHYL]AMIDE; DECANOIC ACID [2 PHENYL 1 (8OXXO 1 OXASPIRO[2.5]OCTA 4,6 DIEN 5 YLCARBAMOYL)ETHYL]AMIDE; MANUMYCIN; MANUMYCIN A; PHOSPHODIESTERASE INHIBITOR; SCYPHOSTATIN; SCYPHOSTATIN DERIVATIVE; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DECANOIC ACID[1 (8 OXO 1 OXASPIRO[2,5]OCTA 4,6 DIEN 5 YLCARBAMOYL)ETHYL]AMIDE; DECANOIC ACID[2 PHENYL 1 (8 OXO 1 OXASPIRO[2,5]OCTA 4,6 DIEN 5 YLCARBAMOYL)ETHYL]AMIDE; EPOXIDE; SPHINGOLIPID; SPIROEPOXIDE;

ANIMAL CELL; ARTICLE; BRAIN MICROSOME; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; RAT; CHEMICAL REACTION; DRUG ACTIVITY; DRUG STRUCTURE; REACTION ANALYSIS;

AMIDES; ANIMALS; BRAIN; ENZYME INHIBITORS; EPOXY COMPOUNDS; MICROSOMES; PYRONES; RATS; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 0034810330     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(01)00165-1     Document Type: Article

References (16)