Circulating complement proteins in multiple trauma patients - Correlation with injury severity, development of sepsis, and outcome

Critical Care Medicine

Volumn 25, Issue 12, 1997, Pages 2015-2024

  Hecke, Friederike ^a   Schmidt, Ulf ^a   Kola, Axel ^a   Bautsch, Wilfried ^a   Klos, Andreas ^a   Köhl, Jörg ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Acute respiratory distress syndrome; Complement protein 3; Complement protein 3a; Complement proteins; Inflammation; Multiple trauma; Sepsis

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3A;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPLEMENT ACTIVATION; DIAGNOSTIC VALUE; DISEASE SEVERITY; HUMAN; HUMAN CELL; INJURY SCALE; OUTCOMES RESEARCH; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; SCORING SYSTEM; SEPSIS; TRAUMATOLOGY;

ACCIDENTS, TRAFFIC; ADULT; COMPLEMENT C3; COMPLEMENT C3A; EMERGENCIES; HUMANS; INJURY SEVERITY SCORE; MULTIPLE TRAUMA; PROSPECTIVE STUDIES; RESPIRATORY DISTRESS SYNDROME, ADULT; SEPSIS;

EID: 0031457117     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199712000-00019     Document Type: Article

References (36)

1. Champion HR, Copes WS, Sacco WJ, et al: The major tramna outcome study: Establishing national norms for trauma care. J Trauma 1990; 30: 1356-1365
2. Baker SP, O'Neill B, Haddon W Jr, et al: The injury severity score: A method for describing patients with multiple injuries and evaluating emergency care. J Trauma 1974; 14:187-196
3. Champion HR, Sacco WJ, Copes WS, et al: A revision of the trauma score. J Trauma 1989; 29:623-629
4. Boyd CR, Toison MA, Copes WS: Evaluating trauma care: The TRISS method. J Trauma 1987; 27:370-378
5. Oestern HJ, Tscheme H, Sturm J, et al: Klassifizierung der Verletzungsschwere. Unfallchirurg 1988; 88:465-472
6. Zoltie N, deDombai FT. The hit and miss of ISS and TRISS. BMJ 1993; 307: 906-909
7. Copes WS, Champion HR, Sacco WJ, et al: Progress in characterization anatomic injury. J Trauma 1990; 30: 1200-1207
8. Zilow G, Sturm JA, Rother U, et al: Complement activation and the prognostic value of C3a in patients at risk of adult respiratory distress syndrome. Clin Exp Immunol 1990; 79:151-157
9. Gerard C, Gerard NP: C5a anaphylatoxin and its seven transmembrane-seg ment receptor. In: Annu Rev Immunol. Donham NP (Ed). Palo Alto, Annual Reviews, 1994; pp 775-808
10. Köhl J, Bitter-Suermann D. Anaphylatoxins. In: Complement in Health and Disease. Whaley K, Loos M, Weiler JM, eds. Dordrecht, Kluwer Academic Publishers, 1993, pp 295-320
11. Haviland DL, McCoy RL, Whitehead WT, et al: Cellular expression of the C5a anaphylatoxin receptor (C5aR): Demonstration of C5aR on nonmyeloid cells of the liver and lung. J Immunol 1995; 54:1861-1869
12. Tonnesen MG, Anderson DC, Springer TA, et al: Adherence of neutrophils to cultured human microvascular endothelial cells. Stimulation by chemotactic peptides and lipid mediators and dependence upon the Mac-1, LFA-1, p 15O, 95 glycoprotein family. J Clin Invest 1989; 83:637-646
13. Sacks T, Moldow CF, Craddock PR, et al: Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage. J Clin Invest 1978; 61:1161-1167
14. Goldstein IM, Weissmann G: Generation of C5-derived lysosomal enzyme-releasing activity (C5a) by lysates of leukocyte lysosomes. J Immunol 1974; 13:1583-1588
15. Kurimoto Y, de-Week AL, Dahinden CA: Interleukin 3-dependent mediator release in basophils triggered by C5a. J Exp Med 1989; 170:467-479
16. Fermandez, HN, Henson PM, Otani A, et al: Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions. J Immunol. 1978; 120:109-115
17. Cochrane CG, Müller-Eberhard HJ. The derivation of two distinct anaphylatoxin activities from the third and fifth components of human complement. J Exp Med 1968;127:371-386
18. Björk J, Hugli TE, Smedegard G: Microvascular effects of anaphylatoxins C3a and C5a. J Immunol 1985; 134: 1115-1119
19. Haeffher-Cavaillon N, Cavaillon JM, Laude M, et al: C3a (C3adesArg) induces production and release of interluekin 1 by cultured human monocytes. J Immunol 1987; 139:794-799
20. Okusawa S, Dinarello CA, Yancey KB, et al: C5a induction of human interleukin 1. Synergistic effect with endotoxin or interferon-gamma. J Immunol 1987; 139:2635-2640
21. Scholz W, McClurg MR, Cardenas GJ, et al: C5a-mediated release of interleukin 6 by human monocytes. Clin Immunol Immunopathol 1990; 57: 297-307
22. Ember JA, Sanderson SD, Hugli TE, et al: Induction of interleukin-8 synthesis from monocytes by human C5a anaphylatoxin. Am J Pathol 1994; 144: 393-403
23. Barton PA, Warren JS: Complement component C5 modulates the systemic tumor necrosis factor response in murine endotoxic shock. Infect Immun 1993; 61:1474-1481
24. Sturm JA, Lewis F Jr, Trentz O, et al: Cardiopulmonary parameters and prognosis after severe multiple trauma. J Trauma 1979; 19:305-318
25. Bone RC, Balk PA, Cerra FB, et al: ACCP/SCCM consensus conference: Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101:1644-1655
26. Stove S, Klos A, Bautsch W, et al: Reevaluation of the storage conditions for blood samples which are used for determination of complement activation. J Immunol Methods 1995; 182:1-5
27. Hartmann H, Lubbers B, Casaretto M, et al: Rapid quantification of C3a and C5a using a combination of Chromatographic and immunoassay procedures. J Immunol Methods 1993; 166:35-44
28. Copes WS, Champion HR, Sacco WJ, et al: The injury severity score revisited. J Trauma 1988; 28:69-77
29. Murphy JG, Cayten CG, Stahl WM: Controlling for the severity of injuries in emergency medicine research. Am J Emergency Med 1990; 8:484-497
30. Roumen RM, Redl H, Schlag G, et al: Inflammatory mediators in relation to the development of multiple organ failure in patients after severe blunt trauma. Crit Care Med 1995; 23:474-480
31. Zilow G, Joka T, Obertacke U, et al: Generation of anaphylatoxin C3a in plasma and bronchoalveolar lavage fluid in trauma patients at risk for the adult respiratory distress syndrome. Crit Care Med 1992; 20:468-473
32. Takabayashi T, Vannier E, Clark BD, et al: A new biologic role for C3a and C3a desArg. J Immunol 1996; 156:3455-3460
33. Crass T, Raffetseder U, Martin U, et al: Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells. Eur J Immunol 1996; 26:1944-1950
34. Stöve S, Weite T, Wagner TOF, et al: Circulating complement proteins in patients with sepsis or systemic inflammatory response syndrome. Clin Diagn Lab Immunol 1996; 3:175-183
35. Hill DA, Lennox AF, Neil MJ, Sheehy JP: Evaluation of TRISS as a means of selecting trauma deaths for clinical peer review. Aust N Z J Surg 1992; 62: 204-208
36. Nast-Kolb D, Waydhas C, Jochum M, et al: Biochemische faktoren als objektive parameter zur prognoseabschätzung beim polytrauma. Unfallchirurg 1992; 95:59-66