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Volumn 19, Issue 4, 2004, Pages 297-307

Medical approaches and future options in chronic activate ulcerative colitis

Author keywords

Antisense; Chronic active ulcerative colitis; Cytokines; Heparin; Immunosuppression

Indexed keywords

ALICAFORSEN; ALPHA INTERFERON; ANTISENSE OLIGONUCLEOTIDE; AZATHIOPRINE; BUDESONIDE; COTRIMOXAZOLE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; ETANERCEPT; FOLIC ACID; FOLINIC ACID; GLUCOCORTICOID; HEPARIN; INFLIXIMAB; INTERFERON; LOW MOLECULAR WEIGHT HEPARIN; MERCAPTOPURINE; MESALAZINE; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NATALIZUMAB; PURINE DERIVATIVE; STEROID; TACROLIMUS; THALIDOMIDE; THIOPURINE METHYLTRANSFERASE; TIOGUANINE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNINDEXED DRUG;

EID: 3042767603     PISSN: 01791958     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00384-003-0569-x     Document Type: Review
Times cited : (9)

References (117)
  • 1
    • 0034772988 scopus 로고    scopus 로고
    • Review article: The treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine
    • Nielsen OH, Vainer B, Rask-Madsen J (2001) Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Aliment Pharmacol Ther 15:1699-1708
    • (2001) Aliment Pharmacol. Ther. , vol.15 , pp. 1699-1708
    • Nielsen, O.H.1    Vainer, B.2    Rask-Madsen, J.3
  • 2
    • 0036272464 scopus 로고    scopus 로고
    • Review article: Maintenance of remission in ulcerative colitis
    • Kamm MA (2002) Review article: maintenance of remission in ulcerative colitis. Aliment Pharmacol Ther 16:21-24
    • (2002) Aliment Pharmacol. Ther. , vol.16 , pp. 21-24
    • Kamm, M.A.1
  • 3
    • 0036278519 scopus 로고    scopus 로고
    • The efficacy of azathioprine for the treatment of inflammatory bowel disease: A 30 year review
    • Fraser AG, Orchard TR, Jewell DP (2002) The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review. Gut 50:485-489
    • (2002) Gut , vol.50 , pp. 485-489
    • Fraser, A.G.1    Orchard, T.R.2    Jewell, D.P.3
  • 10
    • 0034036355 scopus 로고    scopus 로고
    • Normal thiopurine methyltransferase levels do not eliminate 6-mercaptopurine or azathioprine toxicity in children with inflammatory bowel disease
    • Kader HA, Wenner WJ Jr, Telega GW, Maller ES, Baldassano RN (2000) Normal thiopurine methyltransferase levels do not eliminate 6-mercaptopurine or azathioprine toxicity in children with inflammatory bowel disease. J Clin Gastroenterol 30:409-413
    • (2000) J. Clin. Gastroenterol. , vol.30 , pp. 409-413
    • Kader, H.A.1    Wenner Jr., W.J.2    Telega, G.W.3    Maller, E.S.4    Baldassano, R.N.5
  • 11
    • 0034765504 scopus 로고    scopus 로고
    • Pharmacokinetic considerations in the treatment of inflammatory bowel disease
    • Schwab M, Klotz U (2001) Pharmacokinetic considerations in the treatment of inflammatory bowel disease. Clin Pharmacokinet 40:723-751
    • (2001) Clin. Pharmacokinet. , vol.40 , pp. 723-751
    • Schwab, M.1    Klotz, U.2
  • 12
    • 0036721011 scopus 로고    scopus 로고
    • Determination of thiopurine methyltransferase genotype or phenotype optimizes initial dosing of azathioprine for the treatment of Crohn's disease
    • Regueiro M, Mardini H (2002) Determination of thiopurine methyltransferase genotype or phenotype optimizes initial dosing of azathioprine for the treatment of Crohn's disease. J Clin Gastroenterol 35:240-244
    • (2002) J. Clin. Gastroenterol. , vol.35 , pp. 240-244
    • Regueiro, M.1    Mardini, H.2
  • 14
    • 18244377445 scopus 로고    scopus 로고
    • Monitoring azathioprine metabolite levels and thiopurine methyl transferase (TPMT) activity in children with inflammatory bowel disease
    • Paerregaard A, Schmiegelow K (2002) Monitoring azathioprine metabolite levels and thiopurine methyl transferase (TPMT) activity in children with inflammatory bowel disease. Scand J Gastroenterol 37:371-372
    • (2002) Scand. J. Gastroenterol. , vol.37 , pp. 371-372
    • Paerregaard, A.1    Schmiegelow, K.2
  • 15
    • 0036076821 scopus 로고    scopus 로고
    • TPMT in the treatment of Crohn's disease with azathioprine
    • Lennard L (2002) TPMT in the treatment of Crohn's disease with azathioprine. Gut 51:143-146
    • (2002) Gut , vol.51 , pp. 143-146
    • Lennard, L.1
  • 16
    • 0036180977 scopus 로고    scopus 로고
    • Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity
    • McGovern DP, Travis SP, Duley J, Shobowale-Bakre el M, Dalton HR (2002) Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity. Gastroenterology 122:838-839
    • (2002) Gastroenterology , vol.122 , pp. 838-839
    • McGovern, D.P.1    Travis, S.P.2    Duley, J.3    Shobowale-Bakre el, M.4    Dalton, H.R.5
  • 17
    • 0035431092 scopus 로고    scopus 로고
    • Shortcoming in the diagnosis of TPMT deficiency in a patient with Crohn's disease using phenotyping only
    • Schwab M, Schaeffeler E, Marx C, Zanger U, Aulitzky W, Eichelbaum M (2001) Shortcoming in the diagnosis of TPMT deficiency in a patient with Crohn's disease using phenotyping only. Gastroenterology 121:498-499
    • (2001) Gastroenterology , vol.121 , pp. 498-499
    • Schwab, M.1    Schaeffeler, E.2    Marx, C.3    Zanger, U.4    Aulitzky, W.5    Eichelbaum, M.6
  • 19
    • 0035037706 scopus 로고    scopus 로고
    • Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease
    • Cuffari C, Hunt S, Bayless T (2001) Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease. Gut 48:642-646
    • (2001) Gut , vol.48 , pp. 642-646
    • Cuffari, C.1    Hunt, S.2    Bayless, T.3
  • 20
    • 0034771188 scopus 로고    scopus 로고
    • Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
    • Lowry PW, Franklin CL, Weaver AL, Pike MG, Mays DC, Tremaine WJ, Lipsky JJ, Sandborn WJ (2001) Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. Gut 49:665-670
    • (2001) Gut , vol.49 , pp. 665-670
    • Lowry, P.W.1    Franklin, C.L.2    Weaver, A.L.3    Pike, M.G.4    Mays, D.C.5    Tremaine, W.J.6    Lipsky, J.J.7    Sandborn, W.J.8
  • 21
    • 0028843101 scopus 로고
    • The role of genetic variation in thiopurine methyltransferase activity and the efficacy and/or side effects of azathioprine therapy in dermatologic patients
    • Snow JL, Gibson LE (1995) The role of genetic variation in thiopurine methyltransferase activity and the efficacy and/or side effects of azathioprine therapy in dermatologic patients. Arch Dermatol 131:193-197
    • (1995) Arch. Dermatol. , vol.131 , pp. 193-197
    • Snow, J.L.1    Gibson, L.E.2
  • 22
    • 0028293868 scopus 로고
    • The role of leukopenia in the 6-mercaptopurine-induced remission of refractory Crohn's disease
    • Colonna T, Korelitz BI (1994) The role of leukopenia in the 6-mercaptopurine-induced remission of refractory Crohn's disease. Am J Gastroenterol 89:362-366
    • (1994) Am. J. Gastroenterol. , vol.89 , pp. 362-366
    • Colonna, T.1    Korelitz, B.I.2
  • 23
    • 0034812896 scopus 로고    scopus 로고
    • Is neutropenia required for effective maintenance of remission during azathioprine therapy in inflammatory bowel disease?
    • Campbell S, Ghosh S (2001) Is neutropenia required for effective maintenance of remission during azathioprine therapy in inflammatory bowel disease? Eur J Gastroenterol Hepatol 13:1073-1076
    • (2001) Eur. J. Gastroenterol. Hepatol. , vol.13 , pp. 1073-1076
    • Campbell, S.1    Ghosh, S.2
  • 24
    • 0034162598 scopus 로고    scopus 로고
    • Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine
    • Decaux G, Prospert F, Horsmans Y, Desager JP (2000) Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine. J Lab Clin Med 135:256-262
    • (2000) J. Lab. Clin. Med. , vol.135 , pp. 256-262
    • Decaux, G.1    Prospert, F.2    Horsmans, Y.3    Desager, J.P.4
  • 25
    • 0034891450 scopus 로고    scopus 로고
    • An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy
    • Dubinsky MC, Hassard PV, Seidman EG, Kam LY, Abreu MT, Targan SR, Vasiliauskas EA (2001) An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy. Inflamm Bowel Dis 7:181-189
    • (2001) Inflamm. Bowel Dis. , vol.7 , pp. 181-189
    • Dubinsky, M.C.1    Hassard, P.V.2    Seidman, E.G.3    Kam, L.Y.4    Abreu, M.T.5    Targan, S.R.6    Vasiliauskas, E.A.7
  • 27
    • 0037370693 scopus 로고    scopus 로고
    • Hepatotoxicity associated with 6-thioguanine therapy for Crohn's disease
    • Rulyak SJ, Saunders MD, Lee SD (2003) Hepatotoxicity associated with 6-thioguanine therapy for Crohn's disease. J Clin Gastroenterol 36:234-237
    • (2003) J. Clin. Gastroenterol. , vol.36 , pp. 234-237
    • Rulyak, S.J.1    Saunders, M.D.2    Lee, S.D.3
  • 28
    • 0033013272 scopus 로고    scopus 로고
    • Intravenous cyclosporin in ulcerative colitis: A five-year experience
    • Cohen RD, Stein R, Hanauer SB (1999) Intravenous cyclosporin in ulcerative colitis: a five-year experience. Am J Gastroenterol 94:1587-1592
    • (1999) Am. J. Gastroenterol. , vol.94 , pp. 1587-1592
    • Cohen, R.D.1    Stein, R.2    Hanauer, S.B.3
  • 30
    • 0032201035 scopus 로고    scopus 로고
    • Efficacy and efficiency of oral microemulsion cyclosporin versus intravenous and soft gelatin capsule cyclosporin in the treatment of severe steroid-refractory ulcerative colitis: An open-label retrospective trial
    • Actis GC, Aimo G, Priolo G, Moscato D, Rizzetto M, Pagni R (1998) Efficacy and efficiency of oral microemulsion cyclosporin versus intravenous and soft gelatin capsule cyclosporin in the treatment of severe steroid-refractory ulcerative colitis: an open-label retrospective trial. Inflamm Bowel Dis 4:276-279
    • (1998) Inflamm. Bowel Dis. , vol.4 , pp. 276-279
    • Actis, G.C.1    Aimo, G.2    Priolo, G.3    Moscato, D.4    Rizzetto, M.5    Pagni, R.6
  • 31
    • 0029786283 scopus 로고    scopus 로고
    • Treatment of acute a steroid-resistant ulcerative colitis with continuous venous infusion of cyclosporine
    • (in Italian)
    • Rosselli M, Casa A, Oliva L, Orlando A, Cottone M (1996) Treatment of acute a steroid-resistant ulcerative colitis with continuous venous infusion of cyclosporine (in Italian). Recenti Prog Med 87:416-421
    • (1996) Recenti Prog. Med. , vol.87 , pp. 416-421
    • Rosselli, M.1    Casa, A.2    Oliva, L.3    Orlando, A.4    Cottone, M.5
  • 32
    • 0345668107 scopus 로고    scopus 로고
    • Randomized double blind comparison of 4 gm/kg versus 2 mg/kg IV cyclosporine in severe ulcerative colitis
    • Van Assche G, D'Haens G, Noman M, Hiele M, Asnong K, Aerden I (2002) Randomized double blind comparison of 4 gm/kg versus 2 mg/kg IV cyclosporine in severe ulcerative colitis. Gastroenterology 122:A81
    • (2002) Gastroenterology , vol.122
    • Van Assche, G.1    D'Haens, G.2    Noman, M.3    Hiele, M.4    Asnong, K.5    Aerden, I.6
  • 35
    • 0031686472 scopus 로고    scopus 로고
    • Short- and long-term outcome of patients treated with cyclosporin for severe acute ulcerative colitis
    • Stack WA, Long RG, Hawkey CJ (1998) Short- and long-term outcome of patients treated with cyclosporin for severe acute ulcerative colitis. Aliment Pharmacol Ther 12:973-978
    • (1998) Aliment Pharmacol. Ther. , vol.12 , pp. 973-978
    • Stack, W.A.1    Long, R.G.2    Hawkey, C.J.3
  • 36
    • 0035220388 scopus 로고    scopus 로고
    • Guidelines of the DGVS. Fulminant process. German Society of Digestive and Metabolic Diseases
    • (in German)
    • Stange EF (2001) Guidelines of the DGVS. Fulminant process. German Society of Digestive and Metabolic Diseases (in German). Z Gastroenterol 39:39-42
    • (2001) Z. Gastroenterol. , vol.39 , pp. 39-42
    • Stange, E.F.1
  • 37
    • 0032447773 scopus 로고    scopus 로고
    • Steroid-unresponsive acute attacks of inflammatory bowel disease: Immunomodulation by tacrolimus (FK506)
    • Fellermann K, Ludwig D, Stahl M, David-Walek T, Stange EF (1998) Steroid-unresponsive acute attacks of inflammatory bowel disease: immunomodulation by tacrolimus (FK506). Am J Gastroenterol 93:1860-1866
    • (1998) Am. J. Gastroenterol. , vol.93 , pp. 1860-1866
    • Fellermann, K.1    Ludwig, D.2    Stahl, M.3    David-Walek, T.4    Stange, E.F.5
  • 40
    • 0037340410 scopus 로고    scopus 로고
    • Methotrexate: First-line or second-line immunomodulator?
    • Fraser AG (2003) Methotrexate: first-line or second-line immunomodulator? Eur J Gastroenterol Hepatol 15:225-231
    • (2003) Eur. J. Gastroenterol. Hepatol. , vol.15 , pp. 225-231
    • Fraser, A.G.1
  • 41
  • 42
    • 0027454451 scopus 로고
    • Low-dose oral methotrexate in refractory inflammatory bowel disease
    • Baron TH, Truss CD, Elson CO (1993) Low-dose oral methotrexate in refractory inflammatory bowel disease. Dig Dis Sci 38:1851-1856
    • (1993) Dig. Dis. Sci. , vol.38 , pp. 1851-1856
    • Baron, T.H.1    Truss, C.D.2    Elson, C.O.3
  • 45
    • 0033679444 scopus 로고    scopus 로고
    • 6-mercaptopurine or methotrexate added to prednisone induces and maintains remission in steroid-dependent inflammatory bowel disease
    • Mate-Jimenez J, Hermida C, Cantero-Perona J, Moreno-Otero R (2000) 6-mercaptopurine or methotrexate added to prednisone induces and maintains remission in steroid-dependent inflammatory bowel disease. Eur J Gastroenterol Hepatol 12:1227-1233
    • (2000) Eur. J. Gastroenterol. Hepatol. , vol.12 , pp. 1227-1233
    • Mate-Jimenez, J.1    Hermida, C.2    Cantero-Perona, J.3    Moreno-Otero, R.4
  • 46
    • 0036791285 scopus 로고    scopus 로고
    • Azathioprine or methotrexate in the treatment of patients with steroid- dependent or steroid-resistant ulcerative colitis: Results of an open-label study on efficacy and tolerability in inducing and maintaining remission
    • Paoluzi OA, Pica R, Marcheggiano A, Crispino P, Iacopini F, Iannoni C, Rivera M, Paoluzi P (2002) Azathioprine or methotrexate in the treatment of patients with steroid- dependent or steroid-resistant ulcerative colitis: results of an open-label study on efficacy and tolerability in inducing and maintaining remission. Aliment Pharmacol Ther 16:1751-1759
    • (2002) Aliment Pharmacol. Ther. , vol.16 , pp. 1751-1759
    • Paoluzi, O.A.1    Pica, R.2    Marcheggiano, A.3    Crispino, P.4    Iacopini, F.5    Iannoni, C.6    Rivera, M.7    Paoluzi, P.8
  • 47
    • 0029961595 scopus 로고    scopus 로고
    • Methotrexate and ulcerative colitis: Wrong drug? Wrong dose? Or wrong disease?
    • Kozarek RA (1996) Methotrexate and ulcerative colitis: wrong drug? Wrong dose? Or wrong disease? Gastroenterology 110:1652-1656
    • (1996) Gastroenterology , vol.110 , pp. 1652-1656
    • Kozarek, R.A.1
  • 51
    • 0037372956 scopus 로고    scopus 로고
    • Safety and efficacy of intravenous pulse cyclophosphamide in acute steroid refractory inflammatory bowel disease
    • Stallmach A, Wittig BM, Moser C, Fischinger J, Duchmann R, Zeitz M (2003) Safety and efficacy of intravenous pulse cyclophosphamide in acute steroid refractory inflammatory bowel disease. Gut 52:377-382
    • (2003) Gut , vol.52 , pp. 377-382
    • Stallmach, A.1    Wittig, B.M.2    Moser, C.3    Fischinger, J.4    Duchmann, R.5    Zeitz, M.6
  • 55
    • 0003059415 scopus 로고    scopus 로고
    • Infliximab for patients with refractory ulcerative colitis
    • Chey WY (2001) Infliximab for patients with refractory ulcerative colitis. Inflamm Bowel Dis 7 [Suppl 1]:S30-S33
    • (2001) Inflamm. Bowel Dis. , vol.7 , Issue.SUPPL. 1
    • Chey, W.Y.1
  • 56
    • 0035905514 scopus 로고    scopus 로고
    • Infliximab in severe steroid-refractory ulcerative colitis: A pilot study
    • Kaser A, Mairinger T, Vogel W, Tilg H (2001) Infliximab in severe steroid-refractory ulcerative colitis: a pilot study. Wien Klin Wochenschr 113:930-933
    • (2001) Wien Klin. Wochenschr. , vol.113 , pp. 930-933
    • Kaser, A.1    Mairinger, T.2    Vogel, W.3    Tilg, H.4
  • 57
    • 0036743233 scopus 로고    scopus 로고
    • Anti-tumour necrosis factor alpha (infliximab) in the treatment of severe ulcerative colitis: Result of an open study on 13 patients
    • Kohn A, Prantera C, Pera A, Cosintino R, Sostegni R, Daperno M (2002) Anti-tumour necrosis factor alpha (infliximab) in the treatment of severe ulcerative colitis: result of an open study on 13 patients. Dig Liver Dis 34:626-630
    • (2002) Dig. Liver Dis. , vol.34 , pp. 626-630
    • Kohn, A.1    Prantera, C.2    Pera, A.3    Cosintino, R.4    Sostegni, R.5    Daperno, M.6
  • 60
    • 0038460945 scopus 로고    scopus 로고
    • Infliximab in moderately severe glucocorticoid resistant ulcerative colitis: A randomised controlled trial
    • Probert CS, Hearing SD, Schreiber S, Kuhbacher T, Ghosh S, Arnott ID, Forbes A (2003) Infliximab in moderately severe glucocorticoid resistant ulcerative colitis: a randomised controlled trial. Gut 52:998-1002
    • (2003) Gut , vol.52 , pp. 998-1002
    • Probert, C.S.1    Hearing, S.D.2    Schreiber, S.3    Kuhbacher, T.4    Ghosh, S.5    Arnott, I.D.6    Forbes, A.7
  • 62
    • 0034972180 scopus 로고    scopus 로고
    • What have we learned from the biological therapies in ulcerative colitis?
    • Pena AS (2001) What have we learned from the biological therapies in ulcerative colitis? Am J Gastroenterol 96:1681-1684
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 1681-1684
    • Pena, A.S.1
  • 63
    • 0036066284 scopus 로고    scopus 로고
    • Antiadhesion molecule therapy in inflammatory bowel disease
    • van Assche G, Rutgeerts P (2002) Antiadhesion molecule therapy in inflammatory bowel disease. Inflamm Bowel Dis 8:291-300
    • (2002) Inflamm. Bowel Dis. , vol.8 , pp. 291-300
    • van Assche, G.1    Rutgeerts, P.2
  • 64
    • 0012299123 scopus 로고    scopus 로고
    • Topical NFκB p65 antisense oligonucleotides in patients with active distal colonic IBD. A randomized, controlled pilot trial
    • Lofberg R, Neurath MF, Ost A, Pettersson S (2002) Topical NFκB p65 antisense oligonucleotides in patients with active distal colonic IBD. A randomized, controlled pilot trial. Gastroenterology 122:A60
    • (2002) Gastroenterology , vol.122
    • Lofberg, R.1    Neurath, M.F.2    Ost, A.3    Pettersson, S.4
  • 65
    • 0034967275 scopus 로고    scopus 로고
    • An open-labeled, randomized study comparing systemic interferon-alpha-2A and prednisolone enemas in the treatment of left-sided ulcerative colitis
    • Madsen SM, Schlichting P, Davidsen B, Nielsen OH, Federspiel B, Riis P, Munkholm P (2001) An open-labeled, randomized study comparing systemic interferon-alpha-2A and prednisolone enemas in the treatment of left-sided ulcerative colitis. Am J Gastroenterol 96:1807-1815
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 1807-1815
    • Madsen, S.M.1    Schlichting, P.2    Davidsen, B.3    Nielsen, O.H.4    Federspiel, B.5    Riis, P.6    Munkholm, P.7
  • 66
    • 0031828588 scopus 로고    scopus 로고
    • Interferon alpha (IFN alpha 2a) therapy for herpes virus-associated inflammatory bowel disease (ulcerative colitis and Crohn's disease)
    • Ruther U, Nunnensiek C, Muller HA, Bader H, May U, Jipp P (1998) Interferon alpha (IFN alpha 2a) therapy for herpes virus-associated inflammatory bowel disease (ulcerative colitis and Crohn's disease). Hepatogastroenterology 45:691-699
    • (1998) Hepatogastroenterology , vol.45 , pp. 691-699
    • Ruther, U.1    Nunnensiek, C.2    Muller, H.A.3    Bader, H.4    May, U.5    Jipp, P.6
  • 67
    • 0029151725 scopus 로고
    • Induction of remission by interferon-alpha in patients with chronic active ulcerative colitis
    • Sumer N, Palabiyikoglu M (1995) Induction of remission by interferon-alpha in patients with chronic active ulcerative colitis. Eur J Gastroenterol Hepatol 7:597-602
    • (1995) Eur. J. Gastroenterol. Hepatol. , vol.7 , pp. 597-602
    • Sumer, N.1    Palabiyikoglu, M.2
  • 68
    • 0029101067 scopus 로고
    • Interferon alpha-2A (roferon) as a treatment of inflammatory bowel disease in children and adolescents
    • Hadziselimovic F, Schaub U, Emmons LR (1995) Interferon alpha-2A (roferon) as a treatment of inflammatory bowel disease in children and adolescents. Adv Exp Med Biol 6:1323-1326
    • (1995) Adv. Exp. Med. Biol. , vol.6 , pp. 1323-1326
    • Hadziselimovic, F.1    Schaub, U.2    Emmons, L.R.3
  • 70
    • 0036024194 scopus 로고    scopus 로고
    • Induction and maintenance of clinical remission by interferon-beta in patients with steroid-refractory active ulcerative colitis-an open long- term pilot trial
    • Musch E, Andus T, Malek M (2002) Induction and maintenance of clinical remission by interferon-beta in patients with steroid-refractory active ulcerative colitis-an open long- term pilot trial. Aliment Pharmacol Ther 16:1233-1239
    • (2002) Aliment Pharmacol. Ther. , vol.16 , pp. 1233-1239
    • Musch, E.1    Andus, T.2    Malek, M.3
  • 74
    • 0024344814 scopus 로고
    • Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease
    • Mahida YR, Wu K, Jewell DP (1989) Enhanced production of interleukin 1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis of Crohn's disease. Gut 30:835-838
    • (1989) Gut , vol.30 , pp. 835-838
    • Mahida, Y.R.1    Wu, K.2    Jewell, D.P.3
  • 75
    • 0026607022 scopus 로고
    • Evidence for continuous stimulation of interleukin-6 production in Crohn's disease
    • Gross V, Andus T, Caesar I, Roth M, Scholmerich J (1992) Evidence for continuous stimulation of interleukin-6 production in Crohn's disease. Gastroenterology 102:514-519
    • (1992) Gastroenterology , vol.102 , pp. 514-519
    • Gross, V.1    Andus, T.2    Caesar, I.3    Roth, M.4    Scholmerich, J.5
  • 76
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher EC, Picker LJ (1996) Lymphocyte homing and homeostasis. Science 272:60-66
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 80
    • 0036926156 scopus 로고    scopus 로고
    • Coagulation system and inflammatory bowel disease: Therapeutic and pathophysiologic implications
    • (in German)
    • Folwaczny C (2002) Coagulation system and inflammatory bowel disease: therapeutic and pathophysiologic implications (in German). Z Gastroenterol 40:991-998
    • (2002) Z. Gastroenterol. , vol.40 , pp. 991-998
    • Folwaczny, C.1
  • 83
    • 0030816854 scopus 로고    scopus 로고
    • Treatment of corticosteroid-resistant ulcerative colitis with heparin- A report of 16 cases
    • Evans RC, Wong VS, Morris AI, Rhodes JM (1997) Treatment of corticosteroid-resistant ulcerative colitis with heparin- a report of 16 cases. Aliment Pharmacol Ther 11:1037-1040
    • (1997) Aliment Pharmacol. Ther. , vol.11 , pp. 1037-1040
    • Evans, R.C.1    Wong, V.S.2    Morris, A.I.3    Rhodes, J.M.4
  • 84
    • 0032975985 scopus 로고    scopus 로고
    • Unfractioned heparin in the therapy of patients with highly active inflammatory bowel disease
    • Folwaczny C, Wiebecke B, Loeschke K (1999) Unfractioned heparin in the therapy of patients with highly active inflammatory bowel disease. Am J Gastroenterol 94:1551-1555
    • (1999) Am. J. Gastroenterol. , vol.94 , pp. 1551-1555
    • Folwaczny, C.1    Wiebecke, B.2    Loeschke, K.3
  • 87
    • 0001811919 scopus 로고
    • Heparin, used i. v. and with sulphasalazine, appears to be effective in the treatment of refractory U.C., and warrants larger controlled trials
    • Evans RC, Rhodes JM (1995) Heparin, used i. v. and with sulphasalazine, appears to be effective in the treatment of refractory U.C., and warrants larger controlled trials. Gut 37 [Suppl 2]:A49
    • (1995) Gut , vol.37 , Issue.SUPPL. 2
    • Evans, R.C.1    Rhodes, J.M.2
  • 89
    • 0000316198 scopus 로고    scopus 로고
    • Effect of heparin treatment on extraintestinal manifestations associated with inflammatory bowel disease
    • Iglicki F, Dupas JL (1996) Effect of heparin treatment on extraintestinal manifestations associated with inflammatory bowel disease. Gastroenterology 110:A872
    • (1996) Gastroenterology , vol.110
    • Iglicki, F.1    Dupas, J.L.2
  • 91
    • 0034746960 scopus 로고    scopus 로고
    • Low molecular weight heparin treatment in steroid refractory ulcerative colitis: Clinical outcome and influence on mucosal capillary thrombi
    • Vrij AA, Jansen JM, Schoon EJ, de Bruine A, Hemker HC, Stockbrugger RW (2001) Low molecular weight heparin treatment in steroid refractory ulcerative colitis: clinical outcome and influence on mucosal capillary thrombi. Scand J Gastroenterol [Suppl 234]:41-47
    • (2001) Scand. J. Gastroenterol. , Issue.SUPPL. 234 , pp. 41-47
    • Vrij, A.A.1    Jansen, J.M.2    Schoon, E.J.3    de Bruine, A.4    Hemker, H.C.5    Stockbrugger, R.W.6
  • 95
    • 85046530139 scopus 로고    scopus 로고
    • Heparin therapy for ulcerative colitis
    • discussion 1307-1308
    • Folwaczny C (2001) Heparin therapy for ulcerative colitis. Gastroenterology 120:1307, discussion 1307-1308
    • (2001) Gastroenterology , vol.120 , pp. 1307
    • Folwaczny, C.1
  • 96
    • 1242349667 scopus 로고    scopus 로고
    • Multicenter, randomized, double-blind placebo-controlled trial of Deligoparin (ultra low molecular weight heparin) for active ulcerative colitis
    • Korzenik J, Miner Jr P, Stanton D, Isaacs K, Zimmermann E, Riff D, De Villiers W, Venuti R (2003) Multicenter, randomized, double-blind placebo-controlled trial of Deligoparin (ultra low molecular weight heparin) for active ulcerative colitis. Gastroenterology 124:A67
    • (2003) Gastroenterology , vol.124
    • Korzenik, J.1    Miner Jr., P.2    Stanton, D.3    Isaacs, K.4    Zimmermann, E.5    Riff, D.6    De Villiers, W.7    Venuti, R.8
  • 97
    • 1242304641 scopus 로고    scopus 로고
    • Randomized trial of tinzaparin, a low molecular weight heparin (LMWH), versus placebo in the treatment of mild to moderately active ulcerative colitis
    • Bloom S, Külerich s, Lassen MR, O'Morain C, Forbes A, Orm S (2003) Randomized trial of tinzaparin, a low molecular weight heparin (LMWH), versus placebo in the treatment of mild to moderately active ulcerative colitis. Gastroenterology 124:A67
    • (2003) Gastroenterology , vol.124
    • Bloom, S.1    Külerich, S.2    Lassen, M.R.3    O'Morain, C.4    Forbes, A.5    Orm, S.6
  • 100
    • 0036673179 scopus 로고    scopus 로고
    • Leukocyte apheresis using a centrifugal cell separator in refractory ulcerative colitis: A multicenter open label trial
    • Kohgo Y, Hibi H, Chiba T, Shimoyama T, Muto T, Yamamura K, Popovsky MA (2002) Leukocyte apheresis using a centrifugal cell separator in refractory ulcerative colitis: a multicenter open label trial. Ther Apher 6:255-260
    • (2002) Ther. Apher. , vol.6 , pp. 255-260
    • Kohgo, Y.1    Hibi, H.2    Chiba, T.3    Shimoyama, T.4    Muto, T.5    Yamamura, K.6    Popovsky, M.A.7
  • 101
    • 0035678443 scopus 로고    scopus 로고
    • Effective maintenance leukocytapheresis for patients with steroid dependent or resistant ulcerative colitis
    • Kondo K, Shinoda T, Yoshimoto H, Takazoe M, Hamada T (2001) Effective maintenance leukocytapheresis for patients with steroid dependent or resistant ulcerative colitis. Ther Apher 5:462-465
    • (2001) Ther. Apher. , vol.5 , pp. 462-465
    • Kondo, K.1    Shinoda, T.2    Yoshimoto, H.3    Takazoe, M.4    Hamada, T.5
  • 103
    • 0030943614 scopus 로고    scopus 로고
    • Anti-inflammatory properties of unfractioned heparin in patients with highly active ulcerative colitis: A pilot study
    • Folwaczny C, Fricke H, Endres S, Hartmann G, Jochum M, Loeschke K (1997) Anti-inflammatory properties of unfractioned heparin in patients with highly active ulcerative colitis: a pilot study. Am J Gastroenterol 92:911-912
    • (1997) Am. J. Gastroenterol. , vol.92 , pp. 911-912
    • Folwaczny, C.1    Fricke, H.2    Endres, S.3    Hartmann, G.4    Jochum, M.5    Loeschke, K.6
  • 104
    • 0030848283 scopus 로고    scopus 로고
    • Rectal corticosteroids versus alternative treatments in ulcerative colitis: A meta-analysis
    • Marshall JK, Irvine EJ (1997) Rectal corticosteroids versus alternative treatments in ulcerative colitis: a meta-analysis. Gut 40:775-781
    • (1997) Gut , vol.40 , pp. 775-781
    • Marshall, J.K.1    Irvine, E.J.2
  • 108
    • 3042781036 scopus 로고    scopus 로고
    • Alternative therapeutic approaches in IBD
    • Folwaczny C (1998) Alternative therapeutic approaches in IBD. Proceedings of the Falk Symposium 105:317-327
    • (1998) Proceedings of the Falk Symposium , vol.105 , pp. 317-327
    • Folwaczny, C.1
  • 110
    • 0029797691 scopus 로고    scopus 로고
    • Treatment of left-sided ulcerative colitis with butyrate enemas: A controlled trial
    • Steinhart AH, Hiruki T, Brzezinski A, Baker JP (1996) Treatment of left-sided ulcerative colitis with butyrate enemas: a controlled trial. Aliment Pharmacol Ther 10:729-736
    • (1996) Aliment Pharmacol. Ther. , vol.10 , pp. 729-736
    • Steinhart, A.H.1    Hiruki, T.2    Brzezinski, A.3    Baker, J.P.4
  • 111
    • 0036256021 scopus 로고    scopus 로고
    • Treatment of distal colitis with local anaesthetic agents
    • Bjorck S, Dahlstrom A, Ahlman H (2002) Treatment of distal colitis with local anaesthetic agents. Pharmacol Toxicol 90:173-180
    • (2002) Pharmacol. Toxicol. , vol.90 , pp. 173-180
    • Bjorck, S.1    Dahlstrom, A.2    Ahlman, H.3
  • 115
    • 0031747032 scopus 로고    scopus 로고
    • Outcome of ulcerative colitis after treatment with transdermal nicotine
    • Guslandi M, Tittobello A (1998) Outcome of ulcerative colitis after treatment with transdermal nicotine. Eur J Gastroenterol Hepatol 10:513-515
    • (1998) Eur. J. Gastroenterol. Hepatol. , vol.10 , pp. 513-515
    • Guslandi, M.1    Tittobello, A.2


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