Methotrexate in ulcerative colitis

Alimentary Pharmacology and Therapeutics

Volumn 17, Issue 3, 2003, Pages 479-480

  Siveke, J T ^a   Folwaczny, C ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; AZATHIOPRINE; FOLIC ACID; LIVER ENZYME; METHOTREXATE; PLACEBO; STEROID;

CLINICAL TRIAL; CROHN DISEASE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ENZYME BLOOD LEVEL; HUMAN; IMMUNOMODULATION; LETTER; PRIORITY JOURNAL; PROPHYLAXIS; RASH; REMISSION; SIDE EFFECT; SKIN ALLERGY; TREATMENT FAILURE; ULCERATIVE COLITIS; VITAMIN SUPPLEMENTATION;

ANTI-INFLAMMATORY AGENTS; COLITIS, ULCERATIVE; HUMANS; METHOTREXATE;

EID: 0037325479     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.2003.01480.x     Document Type: Letter

References (6)

1. Paoluzi OA, Pica R, Marcheggiano A, et al. Azathioprine or methotrexate in the treatment of patients with steroid-dependent or steroid-resistant ulcerative colitis: results of an open-label study on efficacy and tolerability in inducing and maintaining remission. Aliment Pharmacol Ther 2002; 16: 1751-9.
2. Fraser AG, Morton D, McGovern D, Travis S, Jewell DP. The efficacy of methotrexate for maintaining remission in inflammatory bowel disease. Aliment Pharmacol Ther 2002; 16: 693-7.
3. Lichtenstein GR. Approach to corticosteroid-dependent and corticosteroid-refractory Crohn's disease. Inflamm Bowel Dis 2001; 7(Suppl. 1): S23-9.
4. Feagan BG, Fedorak RN, Irvine EJ, et al. A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators. N Engl J Med 2000; 342: 1627-32.
5. Kozarek RA. Methotrexate and ulcerative colitis: wrong drug? Wrong dose? Or wrong disease? Gastroenterology 1996; 110: 1652-6.
6. van Ede AE, Laan RF, Rood MJ, et al. Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum 2001; 44: 1515-24.