Azathioprine intolerance in patients with IBD may be imidazole-related and is independent of TPMT activity [2]

Gastroenterology

Volumn 122, Issue 3, 2002, Pages 838-839

  McGovern, D P B ^a   Travis, S P L ^a   Duley, J ^a   Shobowale Bakre, El M ^a   Dalton, H R ^a  

^a DERRIFORD HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; IMIDAZOLE DERIVATIVE; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE;

CLINICAL ARTICLE; COLON RESECTION; CROHN DISEASE; DIARRHEA; DRUG BIOAVAILABILITY; DRUG HYPERSENSITIVITY; DRUG METABOLISM; DRUG TOLERABILITY; ENTERITIS; ENZYME ACTIVITY; HEADACHE; HUMAN; LETTER; MYALGIA; NAUSEA; PRIORITY JOURNAL; ULCERATIVE COLITIS; VOMITING;

EID: 0036180977     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/gast.2002.32124     Document Type: Article

References (5)

1. Side effects of azathioprine treatment given for inflammatory bowel disease: A 30 year audit
2. Azathioprine pharmacokinetics after intravenous, oral, delayed release oral and rectal foam administration
3. Rational design of novel immunosuppressive drugs: Analogues of azathioprine lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects
4. High dose azathioprine but not 6-mercaptopurine inhibit the production of pro-inflammatory cytokines in inflammatory bowel diseases: An in vitro study
5. A study of the effects of drugs in prolonging survival of homologous renal transplant in dogs