Autonomic dysfunction may be an under-recognized cause of female fertility disorders

Medical Hypotheses

Volumn 63, Issue 1, 2004, Pages 172-177

  Yun, A Joon ^a   Bazar, Kimberly A ^b   Lee, Patrick Y ^a  

^a STANFORD UNIVERSITY   (United States)

^b San Mateo County Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE;

ADAPTATION; AUTONOMIC DYSFUNCTION; CELLULAR IMMUNITY; FEMALE INFERTILITY; HEART RATE VARIABILITY; HUMAN; IMMUNOLOGICAL TOLERANCE; LUTEAL PHASE; LYMPHATIC SYSTEM; MENSTRUAL CYCLE; MOLECULAR EVOLUTION; NIDATION; NORADRENERGIC SYSTEM; OVULATION; PREGNANCY; PRIORITY JOURNAL; REVIEW; SYMPATHETIC TONE; TH1 CELL; TH2 CELL;

EID: 3042764200     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.02.025     Document Type: Article

References (81)

1. Guasti L., Grimoldi P., Mainardi L.T., et al. Autonomic function and baroreflex sensitivity during a normal ovulatory cycle in humans. Acta Cardiol. 54:1999;209-213
2. Yildirir A., Kabakci G., Akgul E., Tokgozoglu L., Oto A. Effects of menstrual cycle on cardiac autonomic innervation as assessed by heart rate variability. Ann. Noninvasive Electrocardiol. 7:2002;60-63
3. Spaanderman M.E., Van Beek E., Ekhart T.H., Van Eyck J., Cheriex E.C., De Leeuw P.W., et al. Changes in hemodynamic parameters and volume homeostasis with the menstrual cycle among women with a history of preeclampsia. Am J. Obstet. Gynecol. 182:2000;1127-1134
4. Rosano G.M., Leonardo F., Sarrel P.M., Beale C.M., De Luca F., Collins P. Cyclical variation in paroxysmal supraventricular tachycardia in women. Lancet. 347:1996;786-788
5. Mannix L.K. Management of menstrual migraine. Neurology. 9:2003;207-213
6. Foldvary-Schaefer N., Falcone T. Catamenial epilepsy: pathophysiology, diagnosis, and management. Neurology. 61(6 Suppl 2):2003;S2-S15
7. Manber R., Bootzin R.R. Sleep and the menstrual cycle. Health Psychol. 16:1997;209-214
8. Wyman J.B., Heaton K.W., Manning A.P., et al. Variability of colonic function in healthy subjects. Gut. 19:1978;146-150
9. Wald A., Thiel D.H., Hoechstetter L., et al. Gastrointestinal transit: the effect of the menstrual cycle. Gastroenterology. 80:1981;1497-1500
10. Degen L.P., Phillips S.F. Variability of gastrointestinal transit in healthy women and men. Gut. 39:1996;299-305
11. Paterson G.D., Miller S.J.H. Hormonal influence in simple glaucoma. Br. J. Ophthalmol. 47:1963;129-137
12. Dalton K. Influence of menstruation on glaucoma. Br. J. Ophthalmol. 51:1967;692-695
13. Greenstein D., Jeffcote N., Ilsley D., Kester R.C. The menstrual cycle and Raynaud's phenomenon. Angiology. 47:1996;427-436
14. Watanabe M., Nakagawa M., Nobe S., et al. Circadian variation of short-lasting asymptomatic paroxysmal supraventricular tachycardia. J. Electrocardiol. 35:2002;135-138
15. Ablad B., Dahlof C. Migraine and beta-blockade: modulation of sympathetic neurotransmission. Cephalalgia. 6(Suppl 5):1986;7-13
16. Montagna P., Gambetti P., Cortelli P., Lugaresi E. Familial and sporadic fatal insomnia. Lancet Neurol. 2:2003;167-176
17. El-Salhy M. Chronic idiopathic slow transit constipation: pathophysiology and management. Colorectal Dis. 5:2003;288-296
18. Riccadonna M., Covi G., Pancera P., et al. Autonomic system activity and 24-hour blood pressure variations in subjects with normal- and high-tension glaucoma. J. Glaucoma. 12:2003;156-163
19. Charkoudian N. Skin blood flow in adult human thermoregulation: how it works, when it does not, and why. Mayo Clin. Proc. 78:2003;603-612
20. Weihe E., Nohr D., Michel S., et al. Molecular anatomy of the neuro-immune connection. Int. J. Neurosci. 59:1991;1-23
21. Felten S.Y., Felten D.L., Bellinger D.L., et al. Noradrenergic sympathetic innervation of lymphoid organs. Prog. Allergy. 43:1988;14-36
22. Ernst P.B., Song F., Klimpel G.R., et al. Regulation of the mucosal immune response. Am. J. Trop. Med. Hyg. 60:1999;2-9
23. Elenkov I.J., Papanicolaou D.A., Wilder R.L., Chrousos G.P. Modulatory effects of glucocorticoids and catecholamines on human interleukin-12 and interleukin-10 production: clinical implications. Proc. Assoc. Am. Physicians. 108:1996;374-381
24. van der Poll T., Coyle S.M., Barbosa K., Braxton C.C., Lowry S.F. Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during endotoxemia. J. Clin. Invest. 97:1996;713-719
25. Suberville S., Bellocq A., Fouqueray B., et al. Regulation of interleukin-10 production by beta-adrenergic agonists. Eur. J. Immunol. 26:1996;2601-2605
26. Panina-Bordignon P., Mazzeo D., Lucia P.D., et al. Beta2-agonists prevent Th1 development by selective inhibition of interleukin 12. J. Clin. Invest. 100:1997;1513-1519
27. Elenkov I.J., Wilder R.L., Chrousos G.P., Vizi E.S. The sympathetic nerve - an integrative interface between two supersystems: the brain and the immune system. Pharmacol. Rev. 52:2000;595-638
28. Leussink V.I., Jung S., Merschdorf U., Toyka K.V., Gold R. High-dose methylprednisolone therapy in multiple sclerosis induces apoptosis in peripheral blood leukocytes. Arch. Neurol. 58:2001;91-97
29. Elenkov I.J., Chrousos G.P. Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann. N. Y. Acad. Sci. 966:2002;290-303
30. Hassig A A., Kremer H., Liang W.X., Stampfli K. The role of the Th-1 to Th-2 shift of the cytokine profiles of CD4 helper cells in the pathogenesis of autoimmune and hypercatabolic diseases. Med. Hypotheses. 51:1998;59-63
31. Willis C., Morris J.M., Danis V., Gallery E.D. Cytokine production by peripheral blood monocytes during the normal human ovulatory menstrual cycle. Hum. Reprod. 18:2003;1173-1178
32. Ostrowski S.R., Gerstoft J., Pedersen B.K., Ullum H. Impaired production of cytokines is an independent predictor of mortality in HIV-1-infected patients. AIDS. 17:2003;521-530
33. Essa S., Raghupathy R., Pacsa A.S., El-Shazly A., Said T., Azizieh F. Th1-type cytokines production is decreased in kidney transplant recipients with active cytomegalovirus infection. J. Med. Virol. 60:2000;223-229
34. Norbiato G., Bevilacqua M., Vago T., Clerici M. Glucocorticoids and Th-1, Th-2 type cytokines in rheumatoid arthritis, osteoarthritis, asthma, atopic dermatitis and AIDS. Clin. Exp. Rheumatol. 15:1997;315-323
35. Mostad S.B., Kreiss J.K., Ryncarz A., et al. Cervical shedding of herpes simplex virus and cytomegalovirus throughout the menstrual cycle in women infected with human immunodeficiency virus type 1. Am J. Obstet Gynecol. 183:2000;948-955
36. Hanna L. The menstrual cycle and viral load. BETA. 12:1999;18
37. Mysliwska J., Trzonkowski P., Bryl E., Lukaszuk K., Mysliwski A. Lower interleukin-2 and higher serum tumor necrosis factor-a levels are associated with perimenstrual, recurrent, facial Herpes simplex infection in young women. Eur. Cytokine Netw. 11:2000;397-406
38. Fidel P.L. Jr. Immunity to candida. Oral Dis. 8(Suppl 2):2002;69-75
39. Corrigan E.M., Clancy R.L., Dunkley M.L., Eyers F.M., Beagley K.W. Cellular immunity in recurrent vulvovaginal candidiasis. Clin. Exp. Immunol. 111:1998;574-578
40. Sasaki S., Nishikawa S., Miura T., et al. Interleukin-4 and interleukin-10 are involved in host resistance to Staphylococcus aureus infection through regulation of gamma interferon. Infect Immun. 68:2000;2424-2430
41. Keane F.E., Ison C.A., Taylor-Robinson D. A longitudinal study of the vaginal flora over a menstrual cycle. Int. J. STD AIDS. 8:1997;489-494. Links
42. Gangur V., Birmingham N.P., Thanesvorakul S., Joseph S. CCR3 and CXCR3 as drug targets for allergy: principles and potential. Curr. Drug. Targets Inflamm. Allergy. 2:2003;53-62
43. Akdis M., Trautmann A., Klunker S., et al. T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells. FASEB J. 17:2003;1026-1035
44. Jenmalm M.C., Van Snick J., Cormont F., Salman B. Allergen-induced Th1 and Th2 cytokine secretion in relation to specific allergen sensitization and atopic symptoms in children. Clin. Exp. Allergy. 31:2001;1528-1535
45. Friedmann P.S. The pathogenesis of atopic eczema. Hosp. Med. 63:2002;653-656
46. Vestergaard C., Deleuran M., Gesser B., Gronhoj Larsen C. Expression of the T-helper 2-specific chemokine receptor CCR4 on CCR10-positive lymphocytes in atopic dermatitis skin but not in psoriasis skin. Br. J. Dermatol. 149:2003;457-463
47. Aridogan B.C., Yildirim M., Baysal V., Inaloz H.S., Baz K., Kaya S. Serum evels of IL-4, IL-10, IL-12, IL-13 and IFN-gamma in Behcet's disease. J. Dermatol. 30:2003;602-607
48. Caproni M., Giomi B., Cardinali C., et al. Further support for a role for Th2-like cytokines in blister formation of pemphigus. Clin. Immunol. 98:2001;264-271
49. Gibbs C.J., Counts I.I., Lock R., et al. Premenstrual exacerbations of asthma. Thorax. 39:1984;833-836
50. Eliasson O., Scherzer H.H. Recurrent respiratory failure in premenstrual asthma. Conn. Med. 48:1984;777
51. Eliasson O., Scherzer H., DeGraff A.C. Morbidity in asthma in relation to the menstrual cycle. J. Allergy Clin. Immunol. 77:1986;87-94
52. Lam S.M., Huang S.C. Premenstrual asthma: report of a case with hormonal studies. J. Microbiol. Immunol Infect. 31:1998;197-199
53. Hanley S.P. Asthma variation with menstruation. Br J. Dis. Chest. 75:1981;306-308
54. Kiriyama K., Sugiura H., Uehara M. Premenstrual deterioration of skin symptoms in female patients with atopic dermatitis. Dermatology. 206:2003;110-112
55. James M.P., Williams R.M. Benign familial pemphigus-premenstrual exacerbation suppressed by goserelin and oophorectomy. Clin. Exp. Dermatol. 20:1995;54-55
56. Muller N., Riedel M., Gruber R., Ackenheil M., Schwarz M.J. The immune system and schizophrenia. An integrative view. Ann. N. Y. Acad. Sci. 917:2000;456-467
57. Lande R.G., Karamchandani V. Chronic mental illness and the menstrual cycle. J. Am. Osteopath. Assoc. 102:2002;655-659
58. Cutolo M., Sulli A., Seriolo B., Accardo S., Masi A.T. Estrogens, the immune response and autoimmunity. Clin. Exp. Rheumatol. 13:1995;217-226
59. Buggage R.R., Matteson D.M., de Shen F., Sun B., Tuaillon N., Chan C.C. Effect of sex hormones on experimental autoimmune uveoretinitis (EAU). Immunol Invest. 32:2003;259-273
60. Refojo D., Liberman A.C., Giacomini D., et al. Integrating systemic information at the molecular level: cross-talk between steroid receptors and cytokine signaling on different target cells. Ann. NY Acad. Sci. 992:2003;196-204
61. Wilder R.L. Hormones, pregnancy, and autoimmune diseases. Ann. N. Y. Acad. Sci. 840:1998;45-50
62. Piccinni M.P., Scaletti C., Vultaggio A., Maggi E., Romagnani S. Defective production of LIF, M-CSF and Th2-type cytokines by T cells at fetomaternal interface is associated with pregnancy loss. J. Reprod. Immunol. 52:2001;35-43
63. Tsuda H., Michimata T., Sakai M., Nagata K., Nakamura M., Saito S. A novel surface molecule of Th2- and Tc2-type cells, CRTH2 expression on human peripheral and decidual CD4+ and CD8+ T cells during the early stage of pregnancy. Clin. Exp. Immunol. 123:2001;105-111
64. Ekerfelt C., Lidstrom C., Matthiesen L., Berg G., Sharma S., Ernerudh J. Spontaneous secretion of interleukin-4 interleukin-10 and interferon-gamma by first trimester decidual cells. Am. J. Reprod. Immunol. 47:2002;159-166
65. Piccinni M.P., Scaletti C., Mavilia C., et al. Production of IL-4 and leukemia inhibitory factor by T cells of the cumulus oophorus: a favorable microenvironment for pre-implantation embryo development. Eur. J. Immunol. 31:2001;2431-2437
66. Piccinni M.P., Maggi E., Romagnani S. Role of hormone-controlled T-cell cytokines in the maintenance of pregnancy. Biochem. Soc. Trans. 28:2000;212-215
67. Polgar K., Yacono P.W., Golan D.E., Hill J.A. Immune interferon gamma inhibits translational mobility of a plasma membrane protein in preimplantation stage mouse embryos: a T-helper 1 mechanism for immunologic reproductive failure. Am. J. Obstet. Gynecol. 174(1 Pt 1):1996;282-287
68. Piccinni M.P., Beloni L., Livi C., Maggi E., Scarselli G., Romagnani S. Defective production of both leukemia inhibitory factor and type 2 T-helper cytokines by decidual T cells in unexplained recurrent abortions. Nat. Med. 4:1998;1020-1024
69. Michimata T., Sakai M., Miyazaki S., et al. Decrease of T-helper 2 and T-cytotoxic 2 cells at implantation sites occurs in unexplained recurrent spontaneous abortion with normal chromosomal content. Hum. Reprod. 18:2003;1523-1528
70. Kwak-Kim J.Y., Chung-Bang H.S., Ng S.C., et al. Increased T helper 1 cytokine responses by circulating T cells are present in women with recurrent pregnancy losses and in infertile women with multiple implantation failures after IVF. Hum. Reprod. 2003;767-773
71. Lim K.J., Odukoya O.A., Ajjan R.A., Li T.C., Weetman A.P., Cooke I.D. The role of T-helper cytokines in human reproduction. Fertil. Steril. 73:2000;136-142
72. Carp H., Torchinsky A., Fein A., Toder V. Hormones, cytokines and fetal anomalies in habitual abortion. Gynecol. Endocrinol. 15:2001;472-483
73. Gleicher N. Some thoughts on the reproductive autoimmune failure syndrome (RAFS) and Th-1 versus Th-2 immune responses. Am. J. Reprod. Immunol. 48:2002;252-254
74. Piccinni M.P., Scaletti C., Maggi E., Romagnani S. Role of hormone-controlled Th1- and Th2-type cytokines in successful pregnancy. J. Neuroimmunol. 109:2000;30-33
75. Watson A., Vandekerckhove P., Lilford R., Vail A., Brosens I., Hughes E. A meta-analysis of the therapeutic role of oil soluble contrast media at hysterosalpingography: a surprising result? Fertil. Steril. 61(3):1994;470-477
76. Rasmussen F., Lindequist S., Larsen C., Justesen P. Therapeutic effect of hysterosalpingography: oil-versus water-soluble contrast media - a randomized prospective study. Radiology. 179(1):1991;75-78
77. Grosch W., Laskawy G. Contribution of linoleic acid to the bitter taste of poppy seeds (Papaver somniferum). Z. Lebensm. Unters. Forsch. 178(4):1984;257-259
78. Switzer K.C., McMurray D.N., Morris J.S., Chapkin R.S. (n-3) Polyunsaturated fatty acids promote activation-induced cell death in murine T lymphocytes J. Nutr. 133(2):2003;496-503
79. Kankaanpaa P., Sutas Y., Salminen S., Lichtenstein A., Isolauri E. Dietary fatty acids and allergy. Ann. Med. 31(4):1999;282-287
80. Stein P.K., Hagley M.T., Cole P.L., Domitrovich P.P., Kleiger R.E., Rottman J.N. Changes in 24-hour heart rate variability during normal pregnancy. Am. J. Obstet. Gynecol. 180:1999;978-985
81. Jayawardana M.A. Baroreceptor sensitivity and haemodynamics in normal pregnancy. J. Obstet. Gynaecol. 21:2001;559-562