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Volumn 37, Issue 7, 2004, Pages 572-578

State of the science: Molecular classifications of breast cancer for clinical diagnostics

Author keywords

Breast cancer; Genomics; Microarray

Indexed keywords

ANTHRACYCLINE; ANTIESTROGEN; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; FLUOROURACIL; FORMALDEHYDE; METHOTREXATE; PACLITAXEL; PARAFFIN; RNA; TAMOXIFEN; TRASTUZUMAB;

EID: 3042681114     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2004.05.002     Document Type: Review
Times cited : (15)

References (71)
  • 1
    • 0033006836 scopus 로고    scopus 로고
    • Cancer Statistics, 1999
    • [1].
    • Landis SH, et al. Cancer Statistics, 1999. CA Cancer J Clin 1999;49(1):8-31 [1].
    • (1999) CA Cancer J Clin , vol.49 , Issue.1 , pp. 8-31
    • Landis, S.H.1
  • 2
    • 0042510536 scopus 로고    scopus 로고
    • Influence of trastuzumab on epirubicin pharmacokinetics in metastatic breast cancer patients
    • Lunardi G., et al. Influence of trastuzumab on epirubicin pharmacokinetics in metastatic breast cancer patients. Ann. Oncol. 14(8):2003;1222-1226
    • (2003) Ann. Oncol. , vol.14 , Issue.8 , pp. 1222-1226
    • Lunardi, G.1
  • 3
    • 8944253777 scopus 로고    scopus 로고
    • Phase II trial of paclitaxel and cisplatin in women with advanced breast cancer: An active regimen with limiting neurotoxicity
    • Wasserheit C., et al. Phase II trial of paclitaxel and cisplatin in women with advanced breast cancer: an active regimen with limiting neurotoxicity. J. Clin. Oncol. 14(7):1996;1993-1999
    • (1996) J. Clin. Oncol. , vol.14 , Issue.7 , pp. 1993-1999
    • Wasserheit, C.1
  • 4
    • 0033758714 scopus 로고    scopus 로고
    • Early secondary acute myelogenous leukemia in breast cancer patients after treatment with mitoxantrone, cyclophosphamide, fluorouracil and radiation therapy
    • Linassier C., et al. Early secondary acute myelogenous leukemia in breast cancer patients after treatment with mitoxantrone, cyclophosphamide, fluorouracil and radiation therapy. Ann. Oncol. 11(10):2000;1289-1294
    • (2000) Ann. Oncol. , vol.11 , Issue.10 , pp. 1289-1294
    • Linassier, C.1
  • 5
    • 0033854610 scopus 로고    scopus 로고
    • Increased risk of acute leukemia after adjuvant chemotherapy for breast cancer: A population-based study
    • Chaplain G., et al. Increased risk of acute leukemia after adjuvant chemotherapy for breast cancer: a population-based study. J. Clin. Oncol. 18(15):2000;2836-2842
    • (2000) J. Clin. Oncol. , vol.18 , Issue.15 , pp. 2836-2842
    • Chaplain, G.1
  • 6
    • 0037900002 scopus 로고    scopus 로고
    • Second malignancies following adjuvant chemotherapy: 6-year results from a Belgian randomized study comparing cyclophosphamide, methotrexate and 5-fluorouracil (CMF) with an anthracycline-based regimen in adjuvant treatment of node-positive breast cancer patients
    • Bernard-Marty C., et al. Second malignancies following adjuvant chemotherapy: 6-year results from a Belgian randomized study comparing cyclophosphamide, methotrexate and 5-fluorouracil (CMF) with an anthracycline-based regimen in adjuvant treatment of node-positive breast cancer patients. Ann. Oncol. 14(5):2003;693-698
    • (2003) Ann. Oncol. , vol.14 , Issue.5 , pp. 693-698
    • Bernard-Marty, C.1
  • 7
    • 0030927336 scopus 로고    scopus 로고
    • Twenty-year follow-up of the breast cancers diagnosed during the Breast Cancer Detection Demonstration Project
    • Smart C.R., et al. Twenty-year follow-up of the breast cancers diagnosed during the Breast Cancer Detection Demonstration Project. CA Cancer J. Clin. 47(3):1997;134-149
    • (1997) CA Cancer J. Clin. , vol.47 , Issue.3 , pp. 134-149
    • Smart, C.R.1
  • 8
    • 0024460767 scopus 로고
    • Pathological prognostic factors in stage I (T1N0M0) and stage II (T1N1M0) breast carcinoma: A study of 644 patients with median follow-up of 18 years
    • Rosen P.P., et al. Pathological prognostic factors in stage I (T1N0M0) and stage II (T1N1M0) breast carcinoma: a study of 644 patients with median follow-up of 18 years. J. Clin. Oncol. 7(9):1989;1239-1251
    • (1989) J. Clin. Oncol. , vol.7 , Issue.9 , pp. 1239-1251
    • Rosen, P.P.1
  • 9
    • 3042685792 scopus 로고    scopus 로고
    • F. Greene, D. Page, I. Fleming, A. Fritz, & C. Balch. Chicago (IL): Springer-Verlag
    • AJCC cancer staging handbook. Greene F., Page D., Fleming I., Fritz A., Balch C. Part VII - Breast. 6th edition:2002;257-281 Springer-Verlag, Chicago (IL)
    • (2002) Part VII - Breast 6th Edition , pp. 257-281
  • 10
    • 0009941731 scopus 로고    scopus 로고
    • Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999
    • Fitzgibbons P.L., et al. Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999. Arch. Pathol. Lab. Med. 124(7):2000;966-978
    • (2000) Arch. Pathol. Lab. Med. , vol.124 , Issue.7 , pp. 966-978
    • Fitzgibbons, P.L.1
  • 11
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
    • Elston C.W., Ellis I.O. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology. 19(5):1991;403-410
    • (1991) Histopathology , vol.19 , Issue.5 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 15
    • 0031927983 scopus 로고    scopus 로고
    • Randomized trila of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: National Cancer Institute of Canada Clinical Trials Group
    • Levine M.N., Bramwell V.H., Pritchard K.I., et al. Randomized trila of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer: National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol. 16:1998;2651-2658
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2651-2658
    • Levine, M.N.1    Bramwell, V.H.2    Pritchard, K.I.3
  • 16
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon D.J., et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N. Engl. J. Med. 344(11):2001;783-792
    • (2001) N. Engl. J. Med. , vol.344 , Issue.11 , pp. 783-792
    • Slamon, D.J.1
  • 17
    • 0035795683 scopus 로고    scopus 로고
    • Five versus more than five years of tamoxifen for lymph node-negative breast cancer: Updated findings from the National Surgical Adjuvant Breast and Bowel Project B-14 randomized trial
    • Fisher B., et al. Five versus more than five years of tamoxifen for lymph node-negative breast cancer: updated findings from the National Surgical Adjuvant Breast and Bowel Project B-14 randomized trial. J. Natl. Cancer. Inst. 93(9):2001;684-690
    • (2001) J. Natl. Cancer. Inst. , vol.93 , Issue.9 , pp. 684-690
    • Fisher, B.1
  • 18
    • 0024506261 scopus 로고
    • A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors
    • Fisher B., et al. A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors. N. Engl. J. Med. 320(8):1989;479-484
    • (1989) N. Engl. J. Med. , vol.320 , Issue.8 , pp. 479-484
    • Fisher, B.1
  • 19
    • 0037445127 scopus 로고    scopus 로고
    • Phase II, randomized, double-blind study of two dose levels of arzoxifene in patients with locally advanced or metastatic breast cancer
    • Buzdar A., et al. Phase II, randomized, double-blind study of two dose levels of arzoxifene in patients with locally advanced or metastatic breast cancer. J. Clin. Oncol. 21(6):2003;1007-1014
    • (2003) J. Clin. Oncol. , vol.21 , Issue.6 , pp. 1007-1014
    • Buzdar, A.1
  • 20
    • 0035101145 scopus 로고    scopus 로고
    • Cellular and molecular pharmacology of antiestrogen action and resistance
    • Clarke R., et al. Cellular and molecular pharmacology of antiestrogen action and resistance. Pharmacol. Rev. 53(1):2001;25-71
    • (2001) Pharmacol. Rev. , vol.53 , Issue.1 , pp. 25-71
    • Clarke, R.1
  • 21
    • 0035915283 scopus 로고    scopus 로고
    • Unraveling resistance to trastuzumab (Herceptin): Insulin-like growth factor-I receptor, a new suspect
    • Albanell J., Baselga J. Unraveling resistance to trastuzumab (Herceptin): insulin-like growth factor-I receptor, a new suspect. J. Natl. Cancer Inst. 93(24):2001;1830-1832
    • (2001) J. Natl. Cancer Inst. , vol.93 , Issue.24 , pp. 1830-1832
    • Albanell, J.1    Baselga, J.2
  • 22
    • 0037325177 scopus 로고    scopus 로고
    • Current perspectives on HER2 testing: A review of national testing guidelines
    • Bilous M., et al. Current perspectives on HER2 testing: a review of national testing guidelines. Mod. Pathol. 16(2):2003;173-182
    • (2003) Mod. Pathol. , vol.16 , Issue.2 , pp. 173-182
    • Bilous, M.1
  • 23
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    • Vogel C.L., et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol. 20(3):2002;719-726
    • (2002) J. Clin. Oncol. , vol.20 , Issue.3 , pp. 719-726
    • Vogel, C.L.1
  • 24
    • 0036814410 scopus 로고    scopus 로고
    • Resistance to trastuzumab: A necessary evil or a temporary challenge?
    • (discussion 258-9.)
    • Cardoso F., et al. Resistance to trastuzumab: a necessary evil or a temporary challenge? Clin. Breast Cancer. 3(4):2002;247-257. (discussion 258-9.)
    • (2002) Clin. Breast Cancer , vol.3 , Issue.4 , pp. 247-257
    • Cardoso, F.1
  • 25
    • 0035931947 scopus 로고    scopus 로고
    • Gene-expression profiles in hereditary breast cancer
    • Hedenfalk I., et al. Gene-expression profiles in hereditary breast cancer. N. Engl. J. Med. 344(8):2001;539-548
    • (2001) N. Engl. J. Med. , vol.344 , Issue.8 , pp. 539-548
    • Hedenfalk, I.1
  • 26
    • 0035881617 scopus 로고    scopus 로고
    • Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns
    • Gruvberger S., et al. Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res. 61(16):2001;5979-5984
    • (2001) Cancer Res. , vol.61 , Issue.16 , pp. 5979-5984
    • Gruvberger, S.1
  • 28
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sørlie T., et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl. Acad. Sci. U. S. A. 98(19):2001;10869-10874
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.19 , pp. 10869-10874
    • Sørlie, T.1
  • 29
    • 0035949684 scopus 로고    scopus 로고
    • Predicting the clinical status of human breast cancer by using gene expression profiles
    • West M., et al. Predicting the clinical status of human breast cancer by using gene expression profiles. Proc. Natl. Acad. Sci. U. S. A. 98(20):2001;11462-11467
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.20 , pp. 11462-11467
    • West, M.1
  • 30
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van 't Veer L.J., et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 415(6871):2002;530-536
    • (2002) Nature , vol.415 , Issue.6871 , pp. 530-536
    • Van 'T Veer, L.J.1
  • 31
    • 0042838307 scopus 로고    scopus 로고
    • Breast cancer classification and prognosis based on gene expression profiles from a population-based study
    • Sotiriou C., et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc. Natl. Acad. Sci. U. S. A. 100(18):2003;10393-10398
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , Issue.18 , pp. 10393-10398
    • Sotiriou, C.1
  • 32
    • 0037381008 scopus 로고    scopus 로고
    • Gene expression-based classification of malignant gliomas correlates better with survival than histological classification
    • Nutt C.L., et al. Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res. 63(7):2003;1602-1607
    • (2003) Cancer Res. , vol.63 , Issue.7 , pp. 1602-1607
    • Nutt, C.L.1
  • 33
    • 0142157702 scopus 로고    scopus 로고
    • Classification of human astrocytic gliomas on the basis of gene expression: A correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes
    • Godard S., et al. Classification of human astrocytic gliomas on the basis of gene expression: a correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes. Cancer Res. 63(20):2003;6613-6625
    • (2003) Cancer Res. , vol.63 , Issue.20 , pp. 6613-6625
    • Godard, S.1
  • 34
    • 0042425741 scopus 로고    scopus 로고
    • Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction
    • van den Boom J., et al. Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am. J. Pathol. 163(3):2003;1033-1043
    • (2003) Am. J. Pathol. , vol.163 , Issue.3 , pp. 1033-1043
    • Van Den Boom, J.1
  • 35
    • 0042567193 scopus 로고    scopus 로고
    • Gene expression profiling identifies molecular subtypes of gliomas
    • Shai R., et al. Gene expression profiling identifies molecular subtypes of gliomas. Oncogene. 22(31):2003;4918-4923
    • (2003) Oncogene , vol.22 , Issue.31 , pp. 4918-4923
    • Shai, R.1
  • 36
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer D.G., et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat. Med. 8:2002;816-824
    • (2002) Nat. Med. , vol.8 , pp. 816-824
    • Beer, D.G.1
  • 37
    • 0035923583 scopus 로고    scopus 로고
    • Diversity of gene expression in adenocarcinoma of the lung
    • Garber M.E., et al. Diversity of gene expression in adenocarcinoma of the lung. Proc. Natl. Acad. Sci. U. S. A. 98(24):2001;13784-13789
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.24 , pp. 13784-13789
    • Garber, M.E.1
  • 38
    • 0035923521 scopus 로고    scopus 로고
    • Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
    • Bhattacharjee A., et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc. Natl. Acad. Sci. U. S. A. 98(24):2001;13790-13795
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.24 , pp. 13790-13795
    • Bhattacharjee, A.1
  • 39
    • 0037014795 scopus 로고    scopus 로고
    • Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers
    • Jazaeri A.A., et al. Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers. J. Natl. Cancer Inst. 94(13):2002;990-1000
    • (2002) J. Natl. Cancer Inst. , vol.94 , Issue.13 , pp. 990-1000
    • Jazaeri, A.A.1
  • 40
    • 0035970050 scopus 로고    scopus 로고
    • Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer
    • Welsh J.B., et al. Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer. Proc. Natl. Acad. Sci. U. S. A. 98(3):2001;1176-1181
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.3 , pp. 1176-1181
    • Welsh, J.B.1
  • 41
    • 19044391072 scopus 로고    scopus 로고
    • Gene expression correlates of clinical prostate cancer behavior
    • Singh D., et al. Gene expression correlates of clinical prostate cancer behavior. Cancer Cell. 1(2):2002;203-209
    • (2002) Cancer Cell , vol.1 , Issue.2 , pp. 203-209
    • Singh, D.1
  • 42
    • 0036682002 scopus 로고    scopus 로고
    • Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease
    • LaTulippe E., et al. Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease. Cancer Res. 62(15):2002;4499-4506
    • (2002) Cancer Res. , vol.62 , Issue.15 , pp. 4499-4506
    • Latulippe, E.1
  • 43
    • 0035881732 scopus 로고    scopus 로고
    • Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer
    • Welsh J.B., et al. Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer. Cancer Res. 61(16):2001;5974-5978
    • (2001) Cancer Res. , vol.61 , Issue.16 , pp. 5974-5978
    • Welsh, J.B.1
  • 44
    • 0035939903 scopus 로고    scopus 로고
    • Delineation of prognostic biomarkers in prostate cancer
    • Dhanasekaran S.M., et al. Delineation of prognostic biomarkers in prostate cancer. Nature. 412(6849):2001;822-826
    • (2001) Nature , vol.412 , Issue.6849 , pp. 822-826
    • Dhanasekaran, S.M.1
  • 45
    • 0036144678 scopus 로고    scopus 로고
    • Global gene expression analysis of gastric cancer by oligonucleotide microarrays
    • Hippo Y., et al. Global gene expression analysis of gastric cancer by oligonucleotide microarrays. Cancer Res. 62(1):2002;233-240
    • (2002) Cancer Res. , vol.62 , Issue.1 , pp. 233-240
    • Hippo, Y.1
  • 46
    • 0037045589 scopus 로고    scopus 로고
    • Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: A gene-expression study
    • Hofmann W.K., et al. Relation between resistance of Philadelphia- chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study. Lancet. 359(9305):2002;481-486
    • (2002) Lancet , vol.359 , Issue.9305 , pp. 481-486
    • Hofmann, W.K.1
  • 47
    • 17144474314 scopus 로고    scopus 로고
    • Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
    • Ferrando A.A., et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell. 1(1):2002;75-87
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 75-87
    • Ferrando, A.A.1
  • 48
    • 19044399684 scopus 로고    scopus 로고
    • Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling
    • Yeoh E.J. Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell. 1(2):2002;133-143
    • (2002) Cancer Cell , vol.1 , Issue.2 , pp. 133-143
    • Yeoh, E.J.1
  • 49
    • 18244409933 scopus 로고    scopus 로고
    • Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
    • Shipp M.A., et al. Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nat. Med. 8(1):2002;68-74
    • (2002) Nat. Med. , vol.8 , Issue.1 , pp. 68-74
    • Shipp, M.A.1
  • 50
    • 0037142053 scopus 로고    scopus 로고
    • The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
    • Rosenwald A., et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N. Engl. J. Med. 346(25):2002;1937-1947
    • (2002) N. Engl. J. Med. , vol.346 , Issue.25 , pp. 1937-1947
    • Rosenwald, A.1
  • 51
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling [see comments]
    • Alizadeh A.A., et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling [see comments]. Nature. 403(6769):2000;503-511
    • (2000) Nature , vol.403 , Issue.6769 , pp. 503-511
    • Alizadeh, A.A.1
  • 52
    • 0032441150 scopus 로고    scopus 로고
    • Cluster analysis and display of genome-wide expression patterns
    • Eisen M.B. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. U. S. A. 95(25):1998;14863-14868
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , Issue.25 , pp. 14863-14868
    • Eisen, M.B.1
  • 53
    • 13044304179 scopus 로고    scopus 로고
    • Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
    • Perou C.M., et al. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc. Natl. Acad. Sci. U. S. A. 96(16):1999;9212-9217
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , Issue.16 , pp. 9212-9217
    • Perou, C.M.1
  • 54
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou C.M., et al. Molecular portraits of human breast tumours. Nature. 406(6797):2000;747-752
    • (2000) Nature , vol.406 , Issue.6797 , pp. 747-752
    • Perou, C.M.1
  • 55
    • 0036898190 scopus 로고    scopus 로고
    • Molecular portraits and the family tree of cancer
    • (Suppl)
    • Chung C.H., Bernard P.S., Perou C.M. Molecular portraits and the family tree of cancer. Nat. Genet. 32:2002;533-540. (Suppl)
    • (2002) Nat. Genet , vol.32 , pp. 533-540
    • Chung, C.H.1    Bernard, P.S.2    Perou, C.M.3
  • 56
    • 0024306070 scopus 로고
    • Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: Relation to in vivo phenotypes and influence of medium
    • Taylor-Papadimitriou J., et al. Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium. J. Cell Sci. 94(Pt 3):1989;403-413
    • (1989) J. Cell Sci. , vol.94 , Issue.3 PART , pp. 403-413
    • Taylor-Papadimitriou, J.1
  • 57
    • 0037478605 scopus 로고    scopus 로고
    • Repeated observation of breast tumor subtypes in independent gene expression data sets
    • Sorlie T., et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc. Natl. Acad. Sci. U. S. A. 100(14):2003;8418-8423
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , Issue.14 , pp. 8418-8423
    • Sorlie, T.1
  • 58
    • 0037339887 scopus 로고    scopus 로고
    • Grb2 regulates internalization of EGF receptors through clathrin-coated pits
    • Jiang X., et al. Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Mol. Biol. Cell. 14(3):2003;858-870
    • (2003) Mol. Biol. Cell , vol.14 , Issue.3 , pp. 858-870
    • Jiang, X.1
  • 59
    • 13844250828 scopus 로고    scopus 로고
    • Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
    • Pollack J.R., et al. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors. Proc. Natl. Acad. Sci. U. S. A. 99(20):2002;12963-12968
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , Issue.20 , pp. 12963-12968
    • Pollack, J.R.1
  • 60
    • 0037076342 scopus 로고    scopus 로고
    • Initiating oncogenic event determines gene-expression patterns of human breast cancer models
    • Desai K.V., et al. Initiating oncogenic event determines gene-expression patterns of human breast cancer models. Proc. Natl. Acad. Sci. U. S. A. 99(10):2002;6967-6972
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , Issue.10 , pp. 6967-6972
    • Desai, K.V.1
  • 61
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher V., Tibshirani R., Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. U. S. A. 98(9):2001;5116-5121
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.9 , pp. 5116-5121
    • Tusher, V.1    Tibshirani, R.2    Chu, G.3
  • 62
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver M.J., et al. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 347(25):2002;1999-2009
    • (2002) N. Engl. J. Med. , vol.347 , Issue.25 , pp. 1999-2009
    • Van De Vijver, M.J.1
  • 63
    • 0036320413 scopus 로고    scopus 로고
    • Real-time PCR technology for cancer diagnostics
    • Bernard P.S., Wittwer C.T. Real-time PCR technology for cancer diagnostics. Clin. Chem. 48(8):2002;1178-1185
    • (2002) Clin. Chem. , vol.48 , Issue.8 , pp. 1178-1185
    • Bernard, P.S.1    Wittwer, C.T.2
  • 64
    • 0031022694 scopus 로고    scopus 로고
    • Continuous fluorescence monitoring of rapid cycle DNA amplification
    • Wittwer C.T., et al. Continuous fluorescence monitoring of rapid cycle DNA amplification. Biotechniques. 22(1):1997;130-1-134-8
    • (1997) Biotechniques , vol.22 , Issue.1 , pp. 1301-1348
    • Wittwer, C.T.1
  • 65
    • 0028834086 scopus 로고
    • Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization
    • Livak K.J. Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization. PCR Methods Appl. 4(6):1995;357-362
    • (1995) PCR Methods Appl. , vol.4 , Issue.6 , pp. 357-362
    • Livak, K.J.1
  • 66
    • 0029670262 scopus 로고    scopus 로고
    • Molecular beacons: Probes that fluoresce upon hybridization
    • Tyagi S., Kramer F.R. Molecular beacons: probes that fluoresce upon hybridization. Nat. Biotechnol. 14(3):1996;303-308
    • (1996) Nat. Biotechnol. , vol.14 , Issue.3 , pp. 303-308
    • Tyagi, S.1    Kramer, F.R.2
  • 67
    • 0037096071 scopus 로고    scopus 로고
    • Quantification of splice variants using molecular beacon or scorpion primers
    • Taveau M., et al. Quantification of splice variants using molecular beacon or scorpion primers. Anal. Biochem. 305(2):2002;227-235
    • (2002) Anal. Biochem. , vol.305 , Issue.2 , pp. 227-235
    • Taveau, M.1
  • 68
    • 0036580669 scopus 로고    scopus 로고
    • Multiplex quantitative PCR using self-quenched primers labeled with a single fluorophore
    • Nazarenko I., et al. Multiplex quantitative PCR using self-quenched primers labeled with a single fluorophore. Nucleic Acids Res. 30(9):2002;e37
    • (2002) Nucleic Acids Res. , vol.30 , Issue.9 , pp. 37
    • Nazarenko, I.1
  • 69
    • 0032091098 scopus 로고    scopus 로고
    • Quantification of low-copy transcripts by continuous SYBR Green I monitoring during amplification
    • Morrison TB, Weis JJ, Wittwer CT. Quantification of low-copy transcripts by continuous SYBR Green I monitoring during amplification. Biotechniques 1998;24(6):954-8, 960, 962.
    • (1998) Biotechniques , vol.24 , Issue.6 , pp. 954-958
    • Morrison, T.B.1    Weis, J.J.2    Wittwer, C.T.3
  • 71
    • 2442618196 scopus 로고    scopus 로고
    • Profiling breast cancer using real-time quantitative PCR
    • S. Meuer, C. Wittwer, & K. Nakagawara. Heidelberg, Germany: Springer
    • Frank S.G., Bernard P.S. Profiling breast cancer using real-time quantitative PCR. Meuer S., Wittwer C., Nakagawara K. Rapid cycle real-time PCR methods and applications. 2003;95-106 Springer, Heidelberg, Germany
    • (2003) Rapid Cycle Real-time PCR Methods and Applications , pp. 95-106
    • Frank, S.G.1    Bernard, P.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.