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Volumn 24, Issue 4 I, 1996, Pages 882-887

Increasing hepatic cholesterol 7α-hydroxylase reduces plasma cholesterol concentrations in normocholesterolemic and hypercholesterolemic rabbits

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; CHOLESTEROL 7ALPHA MONOOXYGENASE; GLYCODEOXYCHOLIC ACID; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA;

EID: 16044372347     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.1996.v24.pm0008855192     Document Type: Article
Times cited : (24)

References (39)
  • 1
    • 0016382254 scopus 로고
    • Changes in apolipoproteins and properties of rabbit very low density lipoproteins on induction of cholesteremia
    • Shore VG, Shore B, Hart RG. Changes in apolipoproteins and properties of rabbit very low density lipoproteins on induction of cholesteremia. Biochemistry 1974;13:1579-1584.
    • (1974) Biochemistry , vol.13 , pp. 1579-1584
    • Shore, V.G.1    Shore, B.2    Hart, R.G.3
  • 2
    • 0017329378 scopus 로고
    • Chylomicron remnant cholesteryl esters as the major constituent of very low density lipoproteins in plasma of cholesterolfed rabbits
    • Ross AC, Zilversmit DB. Chylomicron remnant cholesteryl esters as the major constituent of very low density lipoproteins in plasma of cholesterolfed rabbits. J Lipid Res 1977;18:169-181.
    • (1977) J Lipid Res , vol.18 , pp. 169-181
    • Ross, A.C.1    Zilversmit, D.B.2
  • 3
    • 0019546058 scopus 로고
    • Saturation and suppression of hepatic lipoprotein receptor: A mechanism for the hypercholesterolemia of cholesterol-fed rabbits
    • Kovanen PT, Brown MS, Basu SK, Bilheimer DW, Goldstein JL. Saturation and suppression of hepatic lipoprotein receptor: a mechanism for the hypercholesterolemia of cholesterol-fed rabbits. Proc Natl Acad Sci USA 1981;78:1396-1400.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 1396-1400
    • Kovanen, P.T.1    Brown, M.S.2    Basu, S.K.3    Bilheimer, D.W.4    Goldstein, J.L.5
  • 4
    • 0026658582 scopus 로고
    • Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7α-hydroxylase activities and mRNA levels in the rat
    • Shefer S, Nguyen LB, Salen G, Ness GC, Chowdhary IR, Lerner S, Batta AK, et al. Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7α-hydroxylase activities and mRNA levels in the rat. J Lipid Res 1992;33:1193-1200.
    • (1992) J Lipid Res , vol.33 , pp. 1193-1200
    • Shefer, S.1    Nguyen, L.B.2    Salen, G.3    Ness, G.C.4    Chowdhary, I.R.5    Lerner, S.6    Batta, A.K.7
  • 5
    • 0028963087 scopus 로고
    • Unexpected inhibition of cholesterol 7α-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits
    • Xu G, Salen G, Shefer S, Ness GC, Nguyen LB, Parker TS, Chen TS, et al. Unexpected inhibition of cholesterol 7α-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits. J Clin Invest 1995;95:1497-1504.
    • (1995) J Clin Invest , vol.95 , pp. 1497-1504
    • Xu, G.1    Salen, G.2    Shefer, S.3    Ness, G.C.4    Nguyen, L.B.5    Parker, T.S.6    Chen, T.S.7
  • 6
    • 0016523453 scopus 로고
    • A heritable hyperlipemic rabbit
    • Kondo T, Watanabe Y. A heritable hyperlipemic rabbit. Exp Anim 1975; 24:89-94.
    • (1975) Exp Anim , vol.24 , pp. 89-94
    • Kondo, T.1    Watanabe, Y.2
  • 7
    • 0019179066 scopus 로고
    • WHHL-rabbit: A low density lipoprotein receptor-deficient animal model for familial hypercholesterolemia
    • Tanzawa K, Shimada Y, Kuroda M, Tsujita Y, Arai M, Watanabe H. WHHL-rabbit: a low density lipoprotein receptor-deficient animal model for familial hypercholesterolemia. Febs Lett 1980;118:81-84.
    • (1980) Febs Lett , vol.118 , pp. 81-84
    • Tanzawa, K.1    Shimada, Y.2    Kuroda, M.3    Tsujita, Y.4    Arai, M.5    Watanabe, H.6
  • 8
    • 0028338785 scopus 로고
    • Dietary cholesterol and downregulation of cholesterol 7α-hydroxylase and cholesterol absorption in African green monkeys
    • Rudel L, Decheiman C, Wilson M, Scobey M, Anderson R. Dietary cholesterol and downregulation of cholesterol 7α-hydroxylase and cholesterol absorption in African green monkeys. J Clin Invest 1994;93:2463-2472.
    • (1994) J Clin Invest , vol.93 , pp. 2463-2472
    • Rudel, L.1    Decheiman, C.2    Wilson, M.3    Scobey, M.4    Anderson, R.5
  • 9
    • 0028986624 scopus 로고
    • Regulation of hepatic 7α-hydroxylase expression and response to dietary cholesterol in the rat and hamster
    • Horton JD, Cuthbert JA, Spady DK. Regulation of hepatic 7α-hydroxylase expression and response to dietary cholesterol in the rat and hamster. J Biol Chem 1995;270:5381-5387.
    • (1995) J Biol Chem , vol.270 , pp. 5381-5387
    • Horton, J.D.1    Cuthbert, J.A.2    Spady, D.K.3
  • 10
    • 0003260266 scopus 로고
    • Expression of cholesterol 7α-hydroxylase in response to cholesterol and bile acid feeding in the hamster and rat
    • Pandak WM, Doerner M, Heuman DM, Hylemon PB, Chiang JYL, Vlahcevic ZR. Expression of cholesterol 7α-hydroxylase in response to cholesterol and bile acid feeding in the hamster and rat [Abstract]. Gastroenterology 1995;108:A1141.
    • (1995) Gastroenterology , vol.108
    • Pandak, W.M.1    Doerner, M.2    Heuman, D.M.3    Hylemon, P.B.4    Chiang, J.Y.L.5    Vlahcevic, Z.R.6
  • 11
    • 0026775156 scopus 로고
    • Regulation of hepatic sterol metabolism in the rat
    • Spady DK, Cuthbert JA. Regulation of hepatic sterol metabolism in the rat. J Biol Chem 1992;267:5584-5591.
    • (1992) J Biol Chem , vol.267 , pp. 5584-5591
    • Spady, D.K.1    Cuthbert, J.A.2
  • 12
    • 0025894157 scopus 로고
    • Regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat
    • Pandak WM, Li YC, Chiang YL, Studer EJ, Gurley EC, Heuman DM, Vlahcevic ZR, et al. Regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat. J Biol Chem 1991;266:3416-3421.
    • (1991) J Biol Chem , vol.266 , pp. 3416-3421
    • Pandak, W.M.1    Li, Y.C.2    Chiang, Y.L.3    Studer, E.J.4    Gurley, E.C.5    Heuman, D.M.6    Vlahcevic, Z.R.7
  • 13
    • 0025269939 scopus 로고
    • Cloning and regulation of cholesterol 7α-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis
    • Jelinek DF, Andersson S, Slaughter CA, Russel DW. Cloning and regulation of cholesterol 7α-hydroxylase, the rate-limiting enzyme in bile acid biosynthesis. J Biol Chem 1990;265:8190-8197.
    • (1990) J Biol Chem , vol.265 , pp. 8190-8197
    • Jelinek, D.F.1    Andersson, S.2    Slaughter, C.A.3    Russel, D.W.4
  • 15
    • 0027433258 scopus 로고
    • Bile acid excretion and cholesterol 7α-hydroxylase expression in hypercholesterolemia-resistant rabbits
    • Poorman JA, Buck RA, Smith SA, Overturf ML, Loose-Mitchell DS. Bile acid excretion and cholesterol 7α-hydroxylase expression in hypercholesterolemia-resistant rabbits. J Lipid Res 1993;34:1675-1685.
    • (1993) J Lipid Res , vol.34 , pp. 1675-1685
    • Poorman, J.A.1    Buck, R.A.2    Smith, S.A.3    Overturf, M.L.4    Loose-Mitchell, D.S.5
  • 16
    • 0018900667 scopus 로고
    • The effect of high and low doses of ursodeoxycholic acid on gallstone dissolution in humans
    • Salen G, Colalilo A, Verga D, Bagan E, Tint GS, Shefer S. The effect of high and low doses of ursodeoxycholic acid on gallstone dissolution in humans. Gastroenterology 1980;78:1412-1418.
    • (1980) Gastroenterology , vol.78 , pp. 1412-1418
    • Salen, G.1    Colalilo, A.2    Verga, D.3    Bagan, E.4    Tint, G.S.5    Shefer, S.6
  • 17
    • 0024408133 scopus 로고
    • Bile acid synthesis in humans: Regulation of hepatic microsomal cholesterol 7α-hydroxylase activity
    • Reihner E, Bjökhem I, Angelin B, Ewerth S, Einarsson K. Bile acid synthesis in humans: regulation of hepatic microsomal cholesterol 7α-hydroxylase activity. Gastroenterology 1989;97:1498-1505.
    • (1989) Gastroenterology , vol.97 , pp. 1498-1505
    • Reihner, E.1    Bjökhem, I.2    Angelin, B.3    Ewerth, S.4    Einarsson, K.5
  • 18
    • 0017571490 scopus 로고
    • Bile acid metabolism in hyperlipoproteinaemia
    • Hellström K, Einarsson K. Bile acid metabolism in hyperlipoproteinaemia. Clin Gastroenterol 1977;6:103-128.
    • (1977) Clin Gastroenterol , vol.6 , pp. 103-128
    • Hellström, K.1    Einarsson, K.2
  • 19
    • 0017401311 scopus 로고
    • An improved procedure for the synthesis of glycine and taurine conjugates of bile acids
    • Tserng KY, Hackey DL, Klein PD. An improved procedure for the synthesis of glycine and taurine conjugates of bile acids. J Lipid Res 1977;18:404-407.
    • (1977) J Lipid Res , vol.18 , pp. 404-407
    • Tserng, K.Y.1    Hackey, D.L.2    Klein, P.D.3
  • 20
    • 0025827270 scopus 로고
    • Control of variance in experimental studies of hyperlipidemia using the WHHL rabbit
    • Donnelly TM, Kelsey SF, Levine DM, Parker TS. Control of variance in experimental studies of hyperlipidemia using the WHHL rabbit. J Lipid Res 1991;32:1089-1098.
    • (1991) J Lipid Res , vol.32 , pp. 1089-1098
    • Donnelly, T.M.1    Kelsey, S.F.2    Levine, D.M.3    Parker, T.S.4
  • 21
    • 0026598057 scopus 로고
    • Glycocholic acid and glycodeoxycholic acid but not glycoursocholic acid inhibit bile acid synthesis in the rabbit
    • Xu G, Salen G, Batta AK, Shefer S, Nguyen LB, Niemann W, Chen TS, et al. Glycocholic acid and glycodeoxycholic acid but not glycoursocholic acid inhibit bile acid synthesis in the rabbit. Gastroenterology 1992;102: 1717-1723.
    • (1992) Gastroenterology , vol.102 , pp. 1717-1723
    • Xu, G.1    Salen, G.2    Batta, A.K.3    Shefer, S.4    Nguyen, L.B.5    Niemann, W.6    Chen, T.S.7
  • 22
    • 0022638140 scopus 로고
    • Ursodeoxycholic acid, 7-ketolithocholic acid, and chenodeoxycholic acid are primary bile acids of the nutria
    • Tint GS, Bullock J, Batta AK, Shefer S, Salen G. Ursodeoxycholic acid, 7-ketolithocholic acid, and chenodeoxycholic acid are primary bile acids of the nutria. Gastroenterology 1986;90:702-709.
    • (1986) Gastroenterology , vol.90 , pp. 702-709
    • Tint, G.S.1    Bullock, J.2    Batta, A.K.3    Shefer, S.4    Salen, G.5
  • 23
    • 0027214419 scopus 로고
    • Different feed back regulation of hepatic cholesterol and bile acid synthesis by glycodeoxycholic acid in rabbits
    • Xu G, Salen G, Shefer S, Batta AK, Ness GC, Nguyen LB, Zhao Z, et al. Different feed back regulation of hepatic cholesterol and bile acid synthesis by glycodeoxycholic acid in rabbits. Gastroenterology 1993;105:1192-1199.
    • (1993) Gastroenterology , vol.105 , pp. 1192-1199
    • Xu, G.1    Salen, G.2    Shefer, S.3    Batta, A.K.4    Ness, G.C.5    Nguyen, L.B.6    Zhao, Z.7
  • 24
    • 0023887374 scopus 로고
    • The effect of abnormal plasma and cellular sterol content and composition on low density lipoprotein uptake and degradation by monocytes and lymphocytes in sitosterolemia with xanthomatosis
    • Nguyen LB, Shefer S, Salen G, Horak I, Tint GS, McNamara DJ. The effect of abnormal plasma and cellular sterol content and composition on low density lipoprotein uptake and degradation by monocytes and lymphocytes in sitosterolemia with xanthomatosis. Metab Clin Exp 1988;37:346-351.
    • (1988) Metab Clin Exp , vol.37 , pp. 346-351
    • Nguyen, L.B.1    Shefer, S.2    Salen, G.3    Horak, I.4    Tint, G.S.5    McNamara, D.J.6
  • 25
    • 33745026603 scopus 로고
    • The distribution and chemical composition of ultracentrifugally separated lipoproteins in human sera
    • Havel RJ, Eder HA, Bragdon JH. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human sera. J Clin Invest 1955;34:1345-1353.
    • (1955) J Clin Invest , vol.34 , pp. 1345-1353
    • Havel, R.J.1    Eder, H.A.2    Bragdon, J.H.3
  • 26
    • 0020973547 scopus 로고
    • Receptor-mediated endocytosis of low density lipoprotein in cultured cells
    • Goldstein JL, Basu SK, Brown MS. Receptor-mediated endocytosis of low density lipoprotein in cultured cells. Methods Enzymol 1983;98:241-260.
    • (1983) Methods Enzymol , vol.98 , pp. 241-260
    • Goldstein, J.L.1    Basu, S.K.2    Brown, M.S.3
  • 27
    • 0025132445 scopus 로고
    • A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis
    • Nguyen LB, Shefer S, Salen G, Ness GC, Tint GS, Zaki G, Rani I. A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis. J Clin Invest 1990;86:923-931.
    • (1990) J Clin Invest , vol.86 , pp. 923-931
    • Nguyen, L.B.1    Shefer, S.2    Salen, G.3    Ness, G.C.4    Tint, G.S.5    Zaki, G.6    Rani, I.7
  • 28
    • 0018607973 scopus 로고
    • Increased binding of low density lipoprotein to liver membranes from rats treated with 17-ethinyl estradiol
    • Kovanen PT, Brown MS, Goldstein JL. Increased binding of low density lipoprotein to liver membranes from rats treated with 17-ethinyl estradiol. J Biol Chem 1979;254:11367-11373.
    • (1979) J Biol Chem , vol.254 , pp. 11367-11373
    • Kovanen, P.T.1    Brown, M.S.2    Goldstein, J.L.3
  • 31
    • 0025337650 scopus 로고
    • Cholesterol-mediated regulation of HMCr-CoA reductase in microsomes from human skin fibroblasts and rat liver
    • George R, Davis PJ, Luong L, Poznansky NJ. Cholesterol-mediated regulation of HMCr-CoA reductase in microsomes from human skin fibroblasts and rat liver. Biochem Cell Biol 1990;68:674-679.
    • (1990) Biochem Cell Biol , vol.68 , pp. 674-679
    • George, R.1    Davis, P.J.2    Luong, L.3    Poznansky, N.J.4
  • 32
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomozynski R, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomozynski, R.1    Sacchi, N.2
  • 33
    • 0015356037 scopus 로고
    • Purification of biologically active globin mRNA by chromatography on oligothymidylic acid-cellulose
    • Aviv N, Ledder P. Purification of biologically active globin mRNA by chromatography on oligothymidylic acid-cellulose. Proc Natl Acad Sci USA 1972;69:1408-1412.
    • (1972) Proc Natl Acad Sci USA , vol.69 , pp. 1408-1412
    • Aviv, N.1    Ledder, P.2
  • 34
    • 0025830753 scopus 로고
    • Feedback regulation of hepatic 3-hydroxy-3-methyl glutaryl coenzyme a reductase activity by dietary cholesterol is not due to altered mRNA levels
    • Ness GC, Keller RK, Pendelton LC. Feedback regulation of hepatic 3-hydroxy-3-methyl glutaryl coenzyme A reductase activity by dietary cholesterol is not due to altered mRNA levels. J Biol Chem 1991;266:14854-14857.
    • (1991) J Biol Chem , vol.266 , pp. 14854-14857
    • Ness, G.C.1    Keller, R.K.2    Pendelton, L.C.3
  • 35
    • 0023097906 scopus 로고
    • Role of receptor-independent low density lipoprotein transport in the maintenance of tissue cholesterol balance in the normal and WHHL rabbit
    • Spady DK, Huettinger M, Bilheimer DW, Dietschy JM. Role of receptor-independent low density lipoprotein transport in the maintenance of tissue cholesterol balance in the normal and WHHL rabbit. J Lipid Res 1987; 28:32-41.
    • (1987) J Lipid Res , vol.28 , pp. 32-41
    • Spady, D.K.1    Huettinger, M.2    Bilheimer, D.W.3    Dietschy, J.M.4
  • 36
    • 0021672163 scopus 로고
    • Partial ileal bypass reduces the production rate of low density lipoproteins in Watanabe heritable hyperlipidemic rabbits
    • Stalenhoef AFH, van Niekerk JLM, Demacker PNM, van't Laar A. Partial ileal bypass reduces the production rate of low density lipoproteins in Watanabe heritable hyperlipidemic rabbits. J Lipid Res 1984;25:1350-1357.
    • (1984) J Lipid Res , vol.25 , pp. 1350-1357
    • Stalenhoef, A.F.H.1    Van Niekerk, J.L.M.2    Demacker, P.N.M.3    Van't Laar, A.4
  • 37
    • 0022482872 scopus 로고
    • Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit
    • Yamamoto T, Bishop RW, Brown MS, Goldstein JL, Russel DW. Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbit. Science 1986;232:1230-1237.
    • (1986) Science , vol.232 , pp. 1230-1237
    • Yamamoto, T.1    Bishop, R.W.2    Brown, M.S.3    Goldstein, J.L.4    Russel, D.W.5
  • 38
    • 0028831356 scopus 로고
    • In vivo gene therapy for hyperlipidemia: Phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene
    • Li J, Fang B, Elsensmith RC, Li XHC, Nasonkin I, Lin-Lee YC, Mims MP, et al. In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene. J Clin Invest 1995;95:768-773.
    • (1995) J Clin Invest , vol.95 , pp. 768-773
    • Li, J.1    Fang, B.2    Elsensmith, R.C.3    Li, X.H.C.4    Nasonkin, I.5    Lin-Lee, Y.C.6    Mims, M.P.7
  • 39
    • 0025845115 scopus 로고
    • Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day
    • Kern F Jr. Normal plasma cholesterol in an 88-year-old man who eats 25 eggs a day. N Engl J Med 1991;324:896-899.
    • (1991) N Engl J Med , vol.324 , pp. 896-899
    • Kern Jr., F.1


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