Intestinal P glycoprotein acts as a natural defense mechanism against Listeria monocytogenes

Infection and Immunity

Volumn 72, Issue 7, 2004, Pages 3849-3854

  Neudeck, Brien L ^a   Loeb, Jennifer M ^a   Faith, Nancy G ^b   Czuprynski, Charles J ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN P; METHIONINE; SULFUR 35; XENOBIOTIC AGENT;

ARTICLE; BACTERIAL INFECTION; CELL STRAIN CACO 2; DEFENSE MECHANISM; GENE OVEREXPRESSION; HOST RESISTANCE; INTESTINE EPITHELIUM; LISTERIA MONOCYTOGENES; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; BACTERIAL PROTEINS; CACO-2 CELLS; DIGOXIN; HOST-PARASITE RELATIONS; HUMANS; IMMUNITY, NATURAL; INTESTINES; LISTERIA INFECTIONS; MICE; P-GLYCOPROTEIN; SULFUR RADIOISOTOPES;

EID: 3042647663     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.7.3849-3854.2004     Document Type: Article

References (31)

1. Ambudkar, S. V., S. Dey, C. A. Hrycyna, M. Ramachandra, I. Pastan, and M. M. Gottesman. 1999. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu. Rev. Pharmacol Toxicol. 39:361-398.
2. Braun, L., B. Ghebrehiwet, and P. Cossart, 2000. gC1q-R/p32, a C1q-binding protein, is a receptor for the InIB invasion protein of Listeria monocytogenes. EMBO J. 19:1458-1466.
3. Braun, L., H. Ohayon, and P. Cossart. 1998. The InIB protein of Listeria monocytogenes is sufficient to promote entry into mammalian cells. Mol. Microbiol. 27:1077-1087.
4. Brombacher, F., and M. Kopf. 1996. Innate versus acquired immunity in listeriosis. Res. Immunol. 147:505-511.
5. Cabanes, D., P. Dehoux, O. Dussurget, L. Frangeul, and P. Cossart. 2002. Surface proteins and the pathogenic potential of Listeria monocytogenes. Trends Microbiol. 10:238-245.
6. Daniels, J. J., I. B. Autenrieth, and W. Goebel. 2000. Interaction of Listeria monocytogenes with the intestinal epithelium. FEMS Microbiol. Lett. 190:323-328.
7. Eisenbraun, M. D., and R. A. Miller, 1999. mdr1a-encoded P-glycoprotein is not required for peripheral T cell proliferation, cytokine release, or cytotoxic effector function in mice. J. Immunol. 163:2621-2627.
8. Eisenbraun, M. D., R. L. Mosley, D. H. Teitelbaum, and R. A. Miller. 2000. Altered development of intestinal intraepithelial lymphocytes in P-glycoprotein-deficient mice. Dev. Comp. Immunol. 24:783-795.
9. Emoto, M., O. Neuhaus, Y. Emoto, and S. H. Kaufmann. 1996. Influence of beta 2-microglobulin expression on gamma interferon secretion and target cell lysis by intraepithelial lymphocytes during intestinal Listeria monocytogenes infection. Infect. Immun. 64:569-575.
10. Hoffmeyer, S., O. Burk, O. von Richter, H. P. Arnold, J. Brockmoller, A. Johne, I. Cascorbi, T. Gerloff, I. Roots, M. Eichelbaum, and U. Brinkmann. 2000. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA 97:3473-3478.
11. Hurd, S., Q. Phan, J. Hadler, B. Mackenzie, S. Lance-Parker, P. Blake, M. Deasy, J. Rankin, et al. 2000. Multistate outbreak of listeriosis - United States 2000. Morbid. Mortal. Wkly. Rep. 50:1129-1130.
12. Kartner, N., J. R. Riordan, and V. Ling. 1983. Cell surface P-glycoprotein associated with multidrug resistance in mammalian cell lines. Science 221:1285-1288.
13. Kim, R. B., M. F. Fromm, C. Wandel, B. Leake, A. J. Wood, D. M. Roden, and G. R. Wilkinson. 1998. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J. Clin. Investig. 101:289-294.
14. Lecuit, M., S. Vandormael-Pournin, J. Lefort, M. Huerre, P. Gounon, C. Dupuy, C. Babinet, and P. Cossart. 2001. A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier. Science 292:1722-1725.
15. Lin, J. H. 2003. Drug-drug interaction mediated by inhibition and induction of P-glycoprotein. Adv. Drug Deliv. Rev. 55:53-81.
16. -/-) mice. Am. J. Pathol. 160:739-751.
17. Meaden, E. R., P. G. Hoggard, B. Maher, S. H. Khoo, and D. J. Back. 2001. Expression of P-glycoprotein and multidrug resistance-associated protein in healthy volunteers and HIV-infected patients. AIDS Res. Hum. Retrovir. 17:1329-1332.
18. Mengaud, J., H. Ohayon, P. Gounon, R. M. Mege, and P. Cossart. 1996. E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells. Cell 84:923-932.
19. Neighbors, M., X. Xu, F. J. Barrat, S. R. Ruuls, T. Churakova, R. Debets, J. F. Bazan, R. A. Kastelein, J. S. Abrams, and A. O'Garra. 2001. A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on Interferon gamma production. J. Exp. Med. 194:343-354.
20. Nishikawa, S., T. Miura, S. Sasaki, and A. Nakane. 1996. The protective role of endogenous cytokines in host resistance against an intragastric infection with Listeria monocytogenes in mice. FEMS Immunol. Med. Microbiol. 16:291-298.
21. Panwala, C. M., J. C. Jones, and J. L. Viney. 1998. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis. J. Immunol. 161:5733-5744.
22. Pavek, P., Z. Fendrich, F. Staud, J. Malakova, H. Brozmanova, M. Laznicek, V. Semecky, M. Grundmann, and V. Palicka. 2001. Influence of P-glycoprotein on the transplacental passage of cyclosporine. J. Pharm. Sci. 90:1583-1592.
23. Prada-Delgado, A., E. Carrasco-Marin, G. M. Bokoch, and C. Alvarez-Dominguez. 2001. Interferon-gamma listericidal action is mediated by novel Rab5a functions at the phagosomal environment. J. Biol. Chem. 276:19059-19065.
24. Schlech, W. F., III, P. M. Lavigne, R. A. Bortolussi, A. C. Allen, E. V. Haldane, A. J. Wort, A. W. Hightower, S. E. Johnson, S. H. King, E. S. Nicholls, and C. V. Broome. 1983. Epidemic listeriosis - evidence for transmission by food. N. Engl. J. Med. 308:203-206.
25. Schultz, M. J., J. Wijnholds, M. P. Peppelenbosch, M. J. Vervoordeldonk, P. Speelman, S. J. van Deventer, P. Borst, and T. van der Poll. 2001. Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia. J. Immunol. 166:4059-4064.
26. Schwab, M., E. Schaeffeler, C. Marx, M. F. Fromm, B. Kaskas, J. Metzler, E. Stange, H. Herfarth, J. Schoelmerich, M. Gregor, S. Walker, I. Cascorbi, I. Roots, U. Brinkmann, U. M. Zanger, and M. Eichelbaum. 2003. Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis. Gastroenterology 124:26-33.
27. Sellon, R. K., S. Tonkonogy, M. Schultz, L. A. Dieleman, W. Grenther, E. Balish, D. M. Rennick, and R. B. Sartor. 1998. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect. Immun. 66:5224-5231.
28. Sparreboom, A., J. van Asperen, U. Mayer, A. H. Schinkel, J. W. Smit, D. K. Meijer, P. Borst, W. J. Nooijen, J. H. Beijnen, and O. van Tellingen. 1997. Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc. Natl. Acad. Sci. USA 94:2031-2035.
29. Ueda, K., I. Pastan, and M. M. Gottesman. 1987. Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene. J. Biol. Chem. 262:17432-17436.
30. Veltkamp, C., S. L. Tonkonogy, Y. P. De Jong, C. Albright, W. B. Grenther, E. Balish, C. Terhorst, and R. B. Sartor. 2001. Continuous stimulation by normal luminal bacteria is essential for the development and perpetuation of colitis in Tg(epsilon26) mice. Gastroenterology 120:900-913.
31. Young, V. B., C. C. Chien, K. A. Knox, N. S. Taylor, D. B. Schauer, and J. G. Fox. 2000. Cytolethal distending toxin in avian and human isolates of Helicobacter pullorum. J. Infect. Dis. 182:620-623.