Influence of P-glycoprotein on the transplacental passage of cyclosporine

Journal of Pharmaceutical Sciences

Volumn 90, Issue 10, 2001, Pages 1583-1592

  Pavek P ^a   Fendrich, Z ^a   Staud, F ^b   Malakova J ^c   Brozmanova H ^a   Laznicek M ^d   Semecky V ^a   Grundmann, M ^a   Palicka, V ^b  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

^c UNIVERSITY HOSPITAL OSTRAVA   (Czech Republic)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cyclosporine; Maternal fetal exchange; P glycoprotein; Pharmaco kinetics; Rats

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHLORPROMAZINE; CYCLOSPORIN; DRUG METABOLITE; GLUCOSE; GLYCOPROTEIN P; QUINIDINE; SODIUM AZIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG PROTEIN BINDING; DRUG TRANSPORT; FEMALE; METABOLIC INHIBITION; NONHUMAN; PLACENTAL TRANSFER; RAT; TROPHOBLAST;

EID: 0034758974     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.1108     Document Type: Article

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