The InlB protein of Listeria monocytogenes is sufficient to promote entry into mammalian cells

Molecular Microbiology

Volumn 27, Issue 5, 1998, Pages 1077-1087

  Braun, Laurence ^a   Ohayon, Hélène ^a   Cossart, Pascale ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; ACTIN; GENTAMICIN; INLB PROTEIN, LISTERIA MONOCYTOGENES; MEMBRANE PROTEIN; MICROSPHERE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTYROSINE; POLYMER;

ARTICLE; BACTERIAL TRANSLOCATION; CYTOSKELETON; HELA CELL; HUMAN; HUMAN CELL; INTERNALIZATION; LISTERIA MONOCYTOGENES; LIVER CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CERCOPITHECUS; CONFOCAL MICROSCOPY; ELECTRON MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; ISOLATION AND PURIFICATION; LISTERIA; METABOLISM; MOVEMENT (PHYSIOLOGY); PATHOGENICITY; PHOSPHORYLATION; PHYSIOLOGY; STAPHYLOCOCCUS; VERO CELL;

LISTERIA MONOCYTOGENES;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; BACTERIAL PROTEINS; CERCOPITHECUS AETHIOPS; FLUORESCENT ANTIBODY TECHNIQUE; GENTAMICINS; LISTERIA; LISTERIA MONOCYTOGENES; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MICROSPHERES; MOVEMENT; PHOSPHORYLATION; PHOSPHOTYROSINE; POLYMERS; STAPHYLOCOCCUS; TUMOR CELLS, CULTURED; VERO CELLS;

EID: 0031594726     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00750.x     Document Type: Article

References (43)

1. Arnold, J., and Boor, P. (1986) Improved transmission electron microscopy (TEM) of cultured cells through a 'floating sheet' method. J Ultrastruct Mol Struct Res 94: 30-36.
2. Braun, L., Dramsi, S., Dehoux, P., Bierne, H., Lindahl, G., and Cossart, P. (1997) InIB: an invasion protein of Listeria monocytogenes with a novel type of surface association. Mol Microbiol 25: 285-294.
3. Campbell, P.A. (1994) Macrophages-Listeria interactions. Macrophage-Pathogen Interactions 313-328.
4. Chen, T., and Gotschlich, E.C. (1996) CGM1a antigen of neutrophils, a receptor of gonococcal opacity proteins. Proc Natl Acad Sci USA 93: 14851-14856.
5. Conlan, J.W., and North, R.J. (1991) Neutrophil-mediated dissolution of infected host cells as a defense strategy against a facultative intracellular bacterium. J Exp Med 174: 741-744.
6. Cossart, P. (1997) Subversion of the mammalian cell cytoskeleton by invasive bacteria. J Clin Invest 99: 2307-2311.
7. Dramsi, S., Dehoux, P., and Cossart, P. (1993) Common features of Gram-positive bacterial proteins involved in cell recognition. Mol Microbiol 9: 1119-1122.
8. Dramsi, S., Biswas, I., Maguin, E., Braun, L., Mastroeni, P., and Cossart, P. (1995) Entry of L. monocytogenes into hepatocytes requires expression of InIB, a surface protein of the internalin multigene family. Mol Microbiol 16: 251-261.
9. Dramsi, S., Dehoux, P., Lebrun, M., Goossens, P., and Cossart, P. (1997) Identification of Four New Members of the Internalin Multigene Family in Listeria monocytogenes strain EGD. Infect Immun 65: 1615-1625.
10. Finlay, B.B. (1994) Molecular and cellular mechanism of Salmonella pathogenesis. Curr Topic Microbiol Immunol 192: 163-185.
11. Finlay, B.B., and Cossart, P. (1997) Exploitation of mammalian host cell functions by bacterial pathogens. Science 276: 718-725.
12. Gaillard, J.L., Berche, P., Mounier, J., Richard, S., and Sansonetti, P.J. (1987) In vitro model of penetration and intracellular growth of L. monocytogenes in the human enterocyte-like cell line Caco-2. Infect Immun 55: 2822-2829.
13. Gaillard, J.-L., Berche, P., Frehel, C., Gouin, E., and Cossart, P. (1991) Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci. Cell 65: 1127-1141.
14. Gaillard, J.L., Jaubert, F., and Berche, P. (1996) The inIAB locus mediates the entry of Listeria monocytogenes into hepatocytes in vivo. J Exp Med 183: 359-369.
15. Galan, J.E. (1996) Molecular genetic bases of Salmonella entry into host cells. Mol Microbiol.20: 263-271.
16. Gouin, E., Dehoux, P., Mengaud, J., Kocks, C., and Cossart, P. (1995) iactA of Listeria ivanovii although distantly related to Listeria monocytogenes actA restores actin tail formation in a L. monocytogenes actA mutant. Infect Immun 63: 2729-2737.
17. Gray, M.L., and Killinger, A.H. (1966) Listeria monocytogenes and listeric infections. Bacteriol Rev 30: 309-382.
18. Gray-Owen, S.D., Dehio, C., Haude, A., Grunert, F., and Meyer, T.F. (1997) CD66 carcinoembryonic antigens mediate interactions between Opa-expressing Neisseria gonorrhoeae and human polymorphonuclear phagocytes. EMBO J 16: 3435-3445.
19. Gregory, S.H., Sagnimeni, A.J., and Wing, E.J. (1996) Expression of the inIAB operon by Listeria monocytogenes is not required for entry into hepatic cells in vivo. Infect Immun 64: 3983-3986.
20. Ireton, K., and Cossart, P. (1997) Host pathogen interactions during entry and actin-based movement of Listeria monocytogenes. Annu Rev Genet 31: 113-138.
21. Ireton, K., Payrastre, B., Chap, H., Ogawa, W., Sakaue, H., Kasuga, M., and Cossart, P. (1996) A role for phosphoinositide 3-kinase in bacterial invasion. Science 274: 780-782.
22. Isberg, R.R. (1991) Discrimination between intracellular uptake and surface adhesion of bacterial pathogens;. Science 252: 934-938.
23. Isberg, R., and Tran Van Nhieu, G. (1994a) Binding and internalization of microorganisms by integrin receptors. Trends Microbiol 2: 10-14.
24. Isberg, R.R., and Tran Van Nhieu, G. (1994b) Two mammalian cell internalization strategies used by pathogenic bacteria. Annu Rev Genet 27: 395-422.
25. Lebrun, M., Mengaud, J., Ohayon, H., Nato, F., and Cossart, P. (1996) Internalin must be on the bacterial surface to mediate entry of Listeria monocytogenes into epithelial cells. Mol Microbiol 21: 579-592.
26. Lecuit, M., Ohayon, H., Braun, L., Mengaud, J., and Cossart, P. (1997) Internalin of Listeria monocytogenes with an intact leucine-rich repeat region is sufficient to promote internalization. Infect Immun 65: 5309-5319.
27. Lingnau, A., Domann, E., Hudel, M., Bock, M., Nichterlein, T., Wehland, J., and Chakraborty, T. (1995) Expression of the Listeria monocytogenes EGD inIA and inIB genes, whose products mediate bacterial entry into tissue culture cell lines, by PrfA-dependent and -independent mechanisms. Infect Immun 63: 3896-3903.
28. MacDonald, T.T., and Carter, P.B. (1980) Cell-mediated immunity to intestinal infection. Infect Immun 28: 516-523.
29. Menard, R., Dehio, C., and Sansonetti, P.J. (1996) Bacterial entry into epithelial cells: the paradigm of Shigella. Trends Microbiol 4: 220-226.
30. Mengaud, J., Ohayon, H., Gounon, P., Mège, R.M., and Cossart, P. (1996a) E-cadherin is the receptor for internalin, a surface protein required for entry of Listeria monocytogenes into epithelial cells. Cell 84: 923-932.
31. Mengaud, J., Lecuit, M., Lebrun, M., Nato, F., Mazié, J.C., and Cossart, P. (1996b) Antibodies to the Leucine-Rich Repeat Region of Internalin Block Entry of Listeria monocytogenes into Cells Expressing E-Cadherin. Infect Immun 64: 5430-5433.
32. Mounier, J., Ryter, A., Coquis-Rondon, M., and Sansonetti, P.J. (1990) Intracellular and cell-to-cell spread of Listeria monocytogenes involves interaction with F-actin in the enterocyte-like cell line Caco-2. Infect Immun 58: 1048-1058.
33. Parsot, C. (1994) Shigella flexneri: Genetics of entry and intracellular dissemination in epithelial cells. Curr Topics Microbiol Immunol 192: 217-243.
34. Racz, P., Tenner, K., and Mérö, E. (1972) Experimental Listeria enteritis. I. An electron microscopic study of the epithelial phase in experimental Listeria infection. Lab Invest 26: 694-700.
35. Rosenshine, I., Duronio, V., and Finlay, B.B. (1992) Protein tyrosine kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells. Infect Immun 60: 2211-2217.
36. Schlech W.F. III, Lavigne, P.M., Bortolussi, R.A., Allen, A.C., Haldane, V.E., Wort, J.A. et al. (1983) Epidemic listeriosis - evidence for transmission by food. N Engl J Med 308: 203-206.
37. Sheehan, B., Kocks, C., Dramsi, S., Gouin, E., Klarsfeld, A., Mengaud, J., and Cossart, P. (1994) Molecular and genetic determinants of the Listeria monocytogenes infectious process. Curr Topics Microbiol Immun 192: 187-216.
38. Swanson, J.A., and Baer, S.C. (1995) Phagocytosis by zippers and triggers. Trends Cell Biol 5: 89-93.
39. Tang, P., Rosenshine, I., and Finlay, B.B. (1994) Listeria monocytogenes, an invasive bacterium, stimulates MAP kinase upon attachment to epithelial cells. Mol Biol Cell 5: 455-464.
40. Van Putten, J.P.M., Weel, J.F.L., and Grassmé, H.U.C. (1994) Measurements of invasion by antibody labeling and electron microscopy. Methods Enzymol 236: 420-437.
41. Velge, P., Bottreau, E., Kaeffer, B., Yurdusev, N., Pardon, P., and Van langendonck, N. (1994) Protein tyrosine kinase inhibitors block the entries of Listeria monocytogenes and Listeria ivanovii into epithelial cells. Microb Path 17: 37-50.
42. Virji, M., Makepeace, K., Ferguson, D.J.P., and Watt, S.M. (1996) Carcinoembryonic antigens (CD66) on epithelial cells and neutrophils are receptors for Opa proteins of pathogenic neisseriae. Mol Microbiol 22: 941-950.
43. 1 integrin promotes entry of the bacteria into mammalian cells. J Exp Med 183: 991-999.