A role for long-lived radicals (LLR) in radiation-induced mutation and persistent chromosomal instability: Counteraction by ascorbate and RibCys but not DMSO

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 551, Issue 1-2, 2004, Pages 255-265

  Waldren, Charles A ^a,b   Vannais, Diane B ^a,b   Ueno, Akiko M ^a,c  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

^c NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

ALCD59 mutation; Chromosomal instability; DMSO; High LET radiation; Long lived radicals (LLR); Mutant spectra; RibCys; Vitamin C

Indexed keywords

2 DEXTRO RIBO(1',2',3',4' TETRAHYDROXYBUTYL)THIAZOLIDINE CARBOXYLIC ACID; ASCORBIC ACID; CARBOXYLIC ACID DERIVATIVE; DIMETHYL SULFOXIDE; LONG LIVED RADICAL; RADICAL; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME FRAGILITY; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; IONIZING RADIATION; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; RADIATION INJURY; X RAY;

ANIMALS; ANTIGENS, CD59; ASCORBIC ACID; CARBON; CHROMOSOMAL INSTABILITY; CRICETINAE; CRICETULUS; DIMETHYL SULFOXIDE; HUMANS; HYBRID CELLS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LINEAR ENERGY TRANSFER; MUTATION; RADIATION-PROTECTIVE AGENTS; THIAZOLES; THIAZOLIDINES;

CRICETINAE; CRICETULUS GRISEUS;

EID: 3042639975     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2004.03.011     Document Type: Article

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