The "Pro-drug" RibCys Decreases the Mutagenicity of High-LET Radiation in Cultured Mammalian Cells

Radiation Research

Volumn 160, Issue 5, 2003, Pages 579-583

  Lenarczyk, M ^a   Ueno, A ^a,e   Vannais, D B ^a,g   Kraemer, S ^b   Kronenberg, A ^c   Roberts, J C ^d   Tatsumi, K ^e   Hei, T K ^f   Waldren, C A ^a,g  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF UTAH   (United States)

^e NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^f Columbia University ^*  (United States)

^g RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 DEXTRO RIBO (1',2',3',4' TETRAHYDROXYBUTYL)THIAZOLIDINE 4 CARBOXYLIC ACID; CARBON; CD59 ANTIGEN; CYSTEINE; GLUTATHIONE; IRON; PRODRUG; RIBOSE; THIAZOLIDINE DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CLONE; CELL CULTURE; CELL DAMAGE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; COSMONAUT; DRUG ACTIVITY; DRUG MECHANISM; DRUG SCREENING; GENOTOXICITY; HAMSTER; HUMAN; HUMAN CELL; HYBRID CELL; HYDROLYSIS; IRRADIATION; MAMMAL CELL; MUTAGENICITY; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INJURY; RADIOBIOLOGY; RING OPENING; SWINE;

ANIMALS; CARBON RADIOISOTOPES; CELL COUNT; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; HYBRID CELLS; IRON RADIOISOTOPES; LINEAR ENERGY TRANSFER; LYMPHOCYTES; MUTATION; PRODRUGS; RADIATION DOSAGE; RADIATION TOLERANCE; RADIATION-PROTECTIVE AGENTS; THIAZOLES; THIAZOLIDINES;

CRICETINAE; MAMMALIA;

EID: 0346335791     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/3065     Document Type: Article

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