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Volumn 36, Issue 3, 2002, Pages 255-263

Protective effects of cimetidine on radiation-induced micronuclei and apoptosis in human peripheral blood lymphocytes

Author keywords

Apoptosis; Cimetidine; Lymphocytes; Micronucleus; Radioprotection

Indexed keywords

CASPASE 3; CIMETIDINE; GLUTATHIONE; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROXYL RADICAL; OXIDE; PHOSPHATIDYLSERINE; RADIOPROTECTIVE AGENT; SCAVENGER;

EID: 0036521940     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760290019264     Document Type: Article
Times cited : (30)

References (38)
  • 1
    • 36849047403 scopus 로고    scopus 로고
    • "History of radioprotector development"
    • Bump, E.A. and Malaker, K., eds, (CRC Press, Boca Raton, Boston)
    • Foye, W.O. (1998) "History of radioprotector development", In: Bump, E.A. and Malaker, K., eds, Radioprotectors: Chemical, Biological, and Clinical Perspectives (CRC Press, Boca Raton, Boston), pp 15-24.
    • (1998) Radioprotectors: Chemical, Biological, and Clinical Perspectives , pp. 15-24
    • Foye, W.O.1
  • 6
    • 0034202443 scopus 로고    scopus 로고
    • "Novel approach to in vivo screening for radioprotective activity in whole mice: In vivo electron spin resonance study probing the redox reaction of nitroxyl"
    • Miura, Y., Anzai, K., Ueda, J. and Ozawa, T. (2000) "Novel approach to in vivo screening for radioprotective activity in whole mice: in vivo electron spin resonance study probing the redox reaction of nitroxyl", Journal of Radiation Research (Tokyo) 41, 103-111.
    • (2000) Journal of Radiation Research (Tokyo) , vol.41 , pp. 103-111
    • Miura, Y.1    Anzai, K.2    Ueda, J.3    Ozawa, T.4
  • 7
    • 0000722702 scopus 로고
    • "Cimetidine anti-ulcer drug as a powerful hydroxyl radical scavenger"
    • Uchida, K. and Kawakishi, S. (1990) "Cimetidine anti-ulcer drug as a powerful hydroxyl radical scavenger", Agricultural and Biological Chemistry 54, 2485-2487.
    • (1990) Agricultural and Biological Chemistry , vol.54 , pp. 2485-2487
    • Uchida, K.1    Kawakishi, S.2
  • 8
    • 0027266033 scopus 로고
    • "Radioprotective effects of cimetidine in mouse bone marrow cells exposed to γ-rays as assayed by the micronucleus test"
    • Mozdarani, H. and Gharbali, A. (1993) "Radioprotective effects of cimetidine in mouse bone marrow cells exposed to γ-rays as assayed by the micronucleus test", International Journal of Radiation Biology 64, 189-194.
    • (1993) International Journal of Radiation Biology , vol.64 , pp. 189-194
    • Mozdarani, H.1    Gharbali, A.2
  • 9
    • 0032512798 scopus 로고    scopus 로고
    • "In vivo protection by cimetidine against fast neutron-induced micronuclei in mouse bone marrow cells"
    • Mozdarani, H. and Khoshbin-Khoshnazar, A.R. (1998) "In vivo protection by cimetidine against fast neutron-induced micronuclei in mouse bone marrow cells", Cancer Letters 124, 65-71.
    • (1998) Cancer Letters , vol.124 , pp. 65-71
    • Mozdarani, H.1    Khoshbin-Khoshnazar, A.R.2
  • 10
    • 0030852822 scopus 로고    scopus 로고
    • "Cimetidine enhances the hepatoprotective action of N-acetylcystein in mice treated with toxic doses of paracetamol"
    • Al-Mustafa, Z.H., Al-Ali, A.K., Qaw, F.S. and Abdul-Cader, Z. (1997) "Cimetidine enhances the hepatoprotective action of N-acetylcystein in mice treated with toxic doses of paracetamol", Toxicology 121, 223-228.
    • (1997) Toxicology , vol.121 , pp. 223-228
    • Al-Mustafa, Z.H.1    Al-Ali, A.K.2    Qaw, F.S.3    Abdul-Cader, Z.4
  • 11
    • 0032416807 scopus 로고    scopus 로고
    • "Antigenotoxic effects of cimetidine against benzene induced micronuclei in mouse bone marrow erythrocytes"
    • Mozdarani, H. and Kamali, S. (1998) "Antigenotoxic effects of cimetidine against benzene induced micronuclei in mouse bone marrow erythrocytes", Toxicology Letters 99, 53-61.
    • (1998) Toxicology Letters , vol.99 , pp. 53-61
    • Mozdarani, H.1    Kamali, S.2
  • 12
    • 0026670819 scopus 로고
    • "Cimetidine as a scavenger of ethanol-induced free radicals"
    • Shaw, S. and Jayatilleke, E. (1992) "Cimetidine as a scavenger of ethanol-induced free radicals", Alcohol 9, 363-367.
    • (1992) Alcohol , vol.9 , pp. 363-367
    • Shaw, S.1    Jayatilleke, E.2
  • 13
    • 0019407319 scopus 로고
    • "Cimetidine protects against acetaminophen hepatotoxicity in rats"
    • Mitchell, M.C., Schenker, S., Avant, G.R. and Speeg, Jr., K.V. (1981) "Cimetidine protects against acetaminophen hepatotoxicity in rats", Gastroenterology 81, 1052-1060.
    • (1981) Gastroenterology , vol.81 , pp. 1052-1060
    • Mitchell, M.C.1    Schenker, S.2    Avant, G.R.3    Speeg K.V., Jr.4
  • 15
    • 0021987630 scopus 로고
    • "Measurement of micronuclei in lymphocytes"
    • Fenech, M. and Morley, A.A. (1985) "Measurement of micronuclei in lymphocytes", Mutation Research 147, 29-36.
    • (1985) Mutation Research , vol.147 , pp. 29-36
    • Fenech, M.1    Morley, A.A.2
  • 16
    • 0027497435 scopus 로고
    • "The cytokinesis-block micronucleus technique: A detailed description of the method and its application to genotoxicity studies in human populations"
    • Fenech, M. (1993) "The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations", Mutation Research 285, 35-44.
    • (1993) Mutation Research , vol.285 , pp. 35-44
    • Fenech, M.1
  • 17
    • 0034693730 scopus 로고    scopus 로고
    • "The in vitro micronucleus technique"
    • Fenech, M. (2000) "The in vitro micronucleus technique", Mutation Research 455, 81-95.
    • (2000) Mutation Research , vol.455 , pp. 81-95
    • Fenech, M.1
  • 18
    • 0025992291 scopus 로고
    • "Biological dosimetry using the micronucleus assay for lymphocytes: Interindividual differences in dose response"
    • Thierens, H., Vral, A. and De Ridder, L. (1991) "Biological dosimetry using the micronucleus assay for lymphocytes: interindividual differences in dose response", Health Physics 61, 623-630.
    • (1991) Health Physics , vol.61 , pp. 623-630
    • Thierens, H.1    Vral, A.2    De Ridder, L.3
  • 19
    • 0026653031 scopus 로고
    • "Study of doserate and split-dose effects on the in vitro micronucleus yield in human lymphocytes exposed to X-rays"
    • Vral, A., Thierens, H. and De Ridder, L. (1992) "Study of doserate and split-dose effects on the in vitro micronucleus yield in human lymphocytes exposed to X-rays", International Journal of Radiation Biology 61, 777-784.
    • (1992) International Journal of Radiation Biology , vol.61 , pp. 777-784
    • Vral, A.1    Thierens, H.2    De Ridder, L.3
  • 20
    • 0027965867 scopus 로고
    • "Dose dependence of radiation-induced micronuclei in cytokinesis-blocked human lymphocytes"
    • Silva, M.J., Carothers, A., Dias, A., Luis, J.H., Piper, J. and Boavida, M.G. (1994) "Dose dependence of radiation-induced micronuclei in cytokinesis-blocked human lymphocytes", Mutation Research 322, 117-128.
    • (1994) Mutation Research , vol.322 , pp. 117-128
    • Silva, M.J.1    Carothers, A.2    Dias, A.3    Luis, J.H.4    Piper, J.5    Boavida, M.G.6
  • 21
    • 0027931260 scopus 로고
    • "Sensitivity of micronucleus induction in human lymphocytes to low-LET radiation qualities: RBE and correlation of RBE and LET"
    • Verhaegen, F. and Vral, A. (1994) "Sensitivity of micronucleus induction in human lymphocytes to low-LET radiation qualities: RBE and correlation of RBE and LET", Radiation Research 139, 208-213.
    • (1994) Radiation Research , vol.139 , pp. 208-213
    • Verhaegen, F.1    Vral, A.2
  • 22
    • 0024356087 scopus 로고
    • "Comparisons of dose-response parameters for radiation-induced acentric fragments and micronuclei observed in cytokinesis-arrested lymphocytes"
    • Littlefield, L.G., Sayer, A.M. and Frome, E.L. (1989) "Comparisons of dose-response parameters for radiation-induced acentric fragments and micronuclei observed in cytokinesis-arrested lymphocytes", Mutagenesis 4, 265-270.
    • (1989) Mutagenesis , vol.4 , pp. 265-270
    • Littlefield, L.G.1    Sayer, A.M.2    Frome, E.L.3
  • 24
    • 0030959840 scopus 로고    scopus 로고
    • "Flow cytometry as a quantitative and sensitive method to evaluate low dose radiation induced apoptosis in vitro in human peripheral blood lymphocytes"
    • Hertveldt, K., Philippe, J., Thierens, H., Cornelissen, M., Vral, A. and De Ridder, L. (1997) "Flow cytometry as a quantitative and sensitive method to evaluate low dose radiation induced apoptosis in vitro in human peripheral blood lymphocytes", International Journal of Radiation Biology 71, 429-433.
    • (1997) International Journal of Radiation Biology , vol.71 , pp. 429-433
    • Hertveldt, K.1    Philippe, J.2    Thierens, H.3    Cornelissen, M.4    Vral, A.5    De Ridder, L.6
  • 25
    • 0030778616 scopus 로고    scopus 로고
    • "Quantification of apoptosis in lymphocytes subsets and effect of apoptosis on apparent expression of membrane antigens"
    • Philippe, J., Louagie, H., Thierens, H., Vral, A., Cornelissen, M. and De Ridder, L. (1997) "Quantification of apoptosis in lymphocytes subsets and effect of apoptosis on apparent expression of membrane antigens", Cytometry 29, 242-249.
    • (1997) Cytometry , vol.29 , pp. 242-249
    • Philippe, J.1    Louagie, H.2    Thierens, H.3    Vral, A.4    Cornelissen, M.5    De Ridder, L.6
  • 26
    • 0002702690 scopus 로고    scopus 로고
    • "Radiation-induced apoptosis in lymphoid cells: Induction, prevention, and molecular mechanisms"
    • Bump, E.A. and Malapert, K., eds, (CRC Press, Boca Raton, Boston)
    • Ramakrishnan, N., Kalinich, J.F. and McClain, D.E. (1998) "Radiation-induced apoptosis in lymphoid cells: induction, prevention, and molecular mechanisms", In: Bump, E.A. and Malapert, K., eds, Radioprotectors: Chemical, Biological, and Clinical Perspectives (CRC Press, Boca Raton, Boston), pp 253-273.
    • (1998) Radioprotectors: Chemical, Biological, and Clinical Perspectives , pp. 253-273
    • Ramakrishnan, N.1    Kalinich, J.F.2    McClain, D.E.3
  • 27
    • 0028149271 scopus 로고
    • "Ionizing radiation induces apoptotic cell death in human TcR-γ/δ + T and natural killer cells without detectable p53 protein"
    • Seki, H., Kanegane, H., Iwai, K., Konno, A., Ohta, K., Yachie, A., Taniguchi, N. and Miyawaki, T. (1994) "Ionizing radiation induces apoptotic cell death in human TcR-γ/δ + T and natural killer cells without detectable p53 protein", European Journal of Immunology 24, 2914-2917.
    • (1994) European Journal of Immunology , vol.24 , pp. 2914-2917
    • Seki, H.1    Kanegane, H.2    Iwai, K.3    Konno, A.4    Ohta, K.5    Yachie, A.6    Taniguchi, N.7    Miyawaki, T.8
  • 28
    • 0027946067 scopus 로고
    • "A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: Performance study of a new miniaturized protocol"
    • Vandeputte, C., Guizon, I., Genestie-Denis, I., Vannier, B. and Lorenzon, G. (1994) "A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: performance study of a new miniaturized protocol", Cell Biology and Toxicology 10, 415-421.
    • (1994) Cell Biology and Toxicology , vol.10 , pp. 415-421
    • Vandeputte, C.1    Guizon, I.2    Genestie-Denis, I.3    Vannier, B.4    Lorenzon, G.5
  • 29
    • 0019167355 scopus 로고
    • "Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine"
    • Griffith, O.W. (1980) "Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine", Analytical Biochemistry 106, 207-212.
    • (1980) Analytical Biochemistry , vol.106 , pp. 207-212
    • Griffith, O.W.1
  • 30
    • 0025043947 scopus 로고
    • "Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples"
    • Baker, M.A., Cerniglia, G.J. and Zaman, A. (1990) "Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples", Analytical Biochemistry 190, 360-365.
    • (1990) Analytical Biochemistry , vol.190 , pp. 360-365
    • Baker, M.A.1    Cerniglia, G.J.2    Zaman, A.3
  • 32
    • 0026733075 scopus 로고
    • "Analysis of radiation-induced micronuclei by fluorescence in situ hybridization (FISH) simultaneously using telomeric and centromeric DNA probes"
    • Miller, B.M., Werner, T., Weier, H.-U. and Nusse, M. (1992) "Analysis of radiation-induced micronuclei by fluorescence in situ hybridization (FISH) simultaneously using telomeric and centromeric DNA probes", Radiation Research 131, 177-185.
    • (1992) Radiation Research , vol.131 , pp. 177-185
    • Miller, B.M.1    Werner, T.2    Weier, H.-U.3    Nusse, M.4
  • 33
    • 0033492999 scopus 로고    scopus 로고
    • "Apoptosis induced by γ irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases"
    • Louagie, H., Schotte, P., Vral, A., Cornelissen, M., Thierens, H., Beyaert, R., De Ridder, L. and Philippe, J. (1999) "Apoptosis induced by γ irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases", Cell Biology International 23, 611-617.
    • (1999) Cell Biology International , vol.23 , pp. 611-617
    • Louagie, H.1    Schotte, P.2    Vral, A.3    Cornelissen, M.4    Thierens, H.5    Beyaert, R.6    De Ridder, L.7    Philippe, J.8
  • 34
    • 0032808030 scopus 로고    scopus 로고
    • "Effects of cimetidine and its metal complexes on nitroblue tetrazolium and ferricytochrome c reduction by superoxide radicals"
    • Kirkova, M., Atanassova, M. and Russanov, E. (1999) "Effects of cimetidine and its metal complexes on nitroblue tetrazolium and ferricytochrome c reduction by superoxide radicals", General Pharmacology 33, 271-276.
    • (1999) General Pharmacology , vol.33 , pp. 271-276
    • Kirkova, M.1    Atanassova, M.2    Russanov, E.3
  • 35
    • 0032950961 scopus 로고    scopus 로고
    • "Mitochondrial and intracellular free-calcium regulation of radiation-induced apoptosis in human leukemic cells"
    • Zhao, Q.-L., Kondo, T., Noda, A. and Fujiwara, Y. (1999) "Mitochondrial and intracellular free-calcium regulation of radiation-induced apoptosis in human leukemic cells", International Journal of Radiation Biology 75, 493-504.
    • (1999) International Journal of Radiation Biology , vol.75 , pp. 493-504
    • Zhao, Q.-L.1    Kondo, T.2    Noda, A.3    Fujiwara, Y.4
  • 37
    • 0034905658 scopus 로고    scopus 로고
    • "Enhancement of hyperthermia-induced apoptosis by a free radical initiator, 2,2′-azobis(2-amidinopropane)dihydrochloride, in human histiocytic lymphoma U937 cells"
    • Li, F.-J., Kondo, T., Zhao, Q.-L., Tanabe, K., Ogawa, R., Li, M. and Arai, Y. (2001) "Enhancement of hyperthermia-induced apoptosis by a free radical initiator, 2,2′-azobis(2-amidinopropane)dihydrochloride, in human histiocytic lymphoma U937 cells", Free Radical Research 35, 281-299.
    • (2001) Free Radical Research , vol.35 , pp. 281-299
    • Li, F.-J.1    Kondo, T.2    Zhao, Q.-L.3    Tanabe, K.4    Ogawa, R.5    Li, M.6    Arai, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.