Tolerance induction by third-party "off-the-shelf" CD4 +CD25+ Treg cells

Experimental Hematology

Volumn 34, Issue 1, 2006, Pages 66-71

  Steiner, David ^a   Brunicki, Noga ^a   Blazar, Bruce R ^a   Bachar Lustig, Esther ^a   Reisner, Yair ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DEPRESSION; BONE MARROW TRANSPLANTATION; CD4+ CD25+ T LYMPHOCYTE; CELL ACTIVITY; CONTROLLED STUDY; FEMALE; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HOST CELL; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REGULATORY T LYMPHOCYTE;

ANIMALS; BONE MARROW TRANSPLANTATION; CELL SURVIVAL; DISEASE MODELS, ANIMAL; FEMALE; GRAFT REJECTION; GRAFT VS HOST DISEASE; INJECTIONS, INTRAVENOUS; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, NUDE; SIROLIMUS; T-LYMPHOCYTES, REGULATORY; TRANSPLANTATION CHIMERA; TRANSPLANTATION IMMUNOLOGY; TRANSPLANTATION TOLERANCE; TRANSPLANTATION, HOMOLOGOUS;

ANIMALIA;

EID: 30344450069     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2005.10.011     Document Type: Article

References (30)

1. + suppressor T cells J Exp Med 193 2001 F41
2. * Annu Rev Immunol 18 2000 423
3. L. Graca, S.P. Cobbold, and H. Waldmann Identification of regulatory T cells in tolerated allografts J Exp Med 195 2002 1641
4. M. Hara, C.I. Kingsley, and M. Niimi IL-10 is required for regulatory T cells to mediate tolerance to alloantigens in vivo J Immunol 166 2001 3789
5. S. Gregori, M. Casorati, S. Amuchastegui, S. Smiroldo, A.M. Davalli, and L. Adorini Regulatory T cells induced by 1 α, 25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance J Immunol 167 2001 1945
6. + T cells induced by donor dendritic cells in allograft tolerance by LF15-0195 treatment J Immunol 168 2002 5058
7. + immunoregulatory T cells: new therapeutics for graft-versus-host disease J Exp Med 196 2002 401
8. + regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation J Exp Med 196 2002 389
9. + immune regulatory cells inhibits graft-versus-host disease lethality Blood 99 2002 3493
10. + T lymphocytes Blood 103 2004 4216
11. + T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation Blood 105 2005 1828
12. + naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state Int Immunol 10 1998 1969
13. + regulatory T cells after infusion to prevent donor lymphocyte infusion-induced lethal acute graft-versus-host disease Biol Blood Marrow Transplant 10 2004 748
14. + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function J Exp Med 193 2001 1295
15. + T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures Blood 104 2004 453
16. +-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function Blood 105 2005 750
17. Q. Tang, K.J. Henriksen, and M. Bi In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes J Exp Med 199 2004 1455
18. + regulatory T cells in vivo J Immunol 170 2003 5008
19. + regulatory T cells by TGF-β induction of transcription factor Foxp3 J Exp Med 198 2003 1875
20. - precursors J Immunol 169 2002 4183
21. + regulatory T cells by peripheral expansion J Immunol 173 2004 7259
22. - cells Proc Natl Acad Sci U S A 102 2005 4103
23. D. Steiner, E. Bachar-Lustig, B.R. Blazar, P.A. Taylor, and Y. Reisner Synergism between CD4CD25 Cells, Rapamycin and Host-Non-Reactive Veto CTLs Enables Engraftment of T Cell Depleted BM Allografts in a Stringent Quantitative Mouse Model for T Cell Mediated Graft Rejection Blood 102 2003 Abstract 119
24. + regulatory T cells in vivo J Exp Med 198 2003 249
25. + regulatory T cells in the steady state J Exp Med 198 2003 737
26. + regulatory T cells by antigen-processing dendritic cells J Exp Med 198 2003 235
27. + immunoregulatory T cells is antigen nonspecific J Immunol 164 2000 183
28. + T-regulatory cells are potent inhibitors of GVHD and BM graft rejection Blood 104 2004 3804
29. high regulatory T cells Blood 104 2004 895
30. + regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia J Clin Invest 112 2003 1688