Synthesis and antimalarial activity of new 3-arylquinoxaline-2-carbonitrile derivatives

Arzneimittel-Forschung/Drug Research

Volumn 55, Issue 12, 2005, Pages 754-761

  Zarranz, Belén ^a   Jaso, Andrés ^a   Aldana, Ignacio ^a   Monge, Antonio ^a   Maurel, Séverine ^b   Deharo, Eric ^b   Jullian, Valérie ^b   Sauvain, Michel ^b  

^a UNIVERSITY OF NAVARRA   (Spain)

^b Hôpital Purpan   (France)

Author keywords

Antimalarial agents; Quinoxaline carbonitrile derivatives, in vitro and in vivo studies, synthesis; Hernatin

Indexed keywords

3 (4 CHLOROPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 3 (4 METHYLPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 3 PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 3 [(4 METHOXYCARBONYL)PHENYL]QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DICHLORO 3 (4 METHYLPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DICHLORO 3 PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DICHLORO 3 [(4 METHOXYCARBONYL)PHENYL]QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DIFLUORO 3 (4 METHYL)PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DIFLUORO 3 (4 METHYLPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DIFLUORO 3 PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DIFLUORO 3 [(4 METHOXYCARBONYL)PHENYL]QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DIMETHYL 3 (4 CHLOROPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DIMETHYL 3 (4 METHYLPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DIMETHYL 3 PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 6,7 DIMETHYL 3 [(4 METHOXYCARBONYL)PHENYL]QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 CHLORO 3 (4 METHYLPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 CHLORO 3 PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 CHLORO 3 [(4 METHOXYCARBONYL)PHENYL]QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 DICHLORO 3 (4 METHYLPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 METHOXY 3 (4 CHLOROPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 METHOXY 3 (4 METHYLPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 METHOXY 3 PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 METHOXY 3 [(4 METHOXYCARBONYL)PHENYL]QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 METHYL 3 (4 CHLOROPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 METHYL 3 (4 METHYLPHENYL)QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 METHYL 3 PHENYLQUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; 7 METHYL 3 [(4 METHOXYCARBONYL)PHENYL]QUINOXALINE 2 CARBONITRILE 1,4 DIOXIDE; CYANIDE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; ERYTHROCYTE; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM;

EID: 29744447563     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296926     Document Type: Article

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