A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part IV. Is a new haem polymerisation inhibition test pertinent for the detection of antimalarial natural products?

Journal of Ethnopharmacology

Volumn 73, Issue 1-2, 2000, Pages 271-275

  Baelmans, R ^a   Deharo, E ^b   Bourdy, G ^b   Munoz V ^a   Quenevo, C ^c   Sauvain, M ^b   Ginsburg, H ^d  

^a Instituto Boliviano de Biologia de Altura   (Bolivia)

^b INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

^c Departamento De La Paz   (Bolivia)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Antimalarial drugs; Bolivia; Haemozoin; Plant extracts; Plasmodium; Polymerisation; Tacana

Indexed keywords

ANTIMALARIAL AGENT; CAESALPININA PLUVIOSA; CHLOROQUINE; CINCHONA EXTRACT; GB 1554; HEMATIN; HEMOZOIN; NATURAL PRODUCT; PLANT EXTRACT; QUININE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; BOLIVIA; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SCREENING; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PROTEIN POLYMERIZATION;

ALOYSIA VIRGATA; BIXA ORELLANA; BOLIVIA; CAESALPINIA PLUVIOSA; MASCAGNIA STANNEA; PLASMODIUM FALCIPARUM; TRICHILIA PLEENEA;

EID: 0033797297     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(00)00330-5     Document Type: Article

References (12)

1. N Basilico E Pagani D Monti P Olliaro D Taramelli A microtitre-based method for measuring the haem polymerisation inhibitory activity (HPIA) of antimalarial drugs Journal of Antimicrobial Chemotherapy 42 1998 55 60
2. G Blauer M Akkawi Investigations of B- and β-haematin Journal of Inorganic Biochemistry 66 1997 145 152
3. A Dorn S.R Vippagunta H Matile A Bubendorf J.L Vennerstrom R.G Ridley A comparison and analysis of several ways to promote haematin (Haem) polymerisation and an assessment of its initiation in vitro Biochemical Pharmacology 55 1998 737 747
4. A Dorn S.R Vippagunta H Matile C Jacquet J.L Vennerstrom R.G Ridley An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials Biochemical Pharmacology 55 1998 727 736
5. F Dorvault L'officine XXIst edn 1982 Vigot Paris
6. T.J Egan H.M Marques The role of haem in the activity of chloroquine and related antimalarial drugs Coordination Chemistry Reviews 192 1999 493 517
7. T.J Egan D.C Ross P.A Adams Quinoline anti-malarial drugs inhibit spontaneous formation of β-haematin (malaria pigment) FEBS Letters 352 1994 54 57
8. D Goldberg A Slater The pathway of Hemoglobin degradation in malaria Parasitology Today 8 1992 280 283
9. D Goldberg A Slater A Cerami G Henderson Hemoglobin degradation in the malaria parasite Plasmodium falciparum , an ordered process in a unique organelle Proceedings of the National Academy of Sciences of the USA 87 1990 931 935
10. V Muñoz M Sauvain G Bourdy J Callapa S Bergeron J.A Bravo L Balderrama B Ortiz A Gimenez E Deharo A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part I. Evaluation of the antimalarial activity of plants used by the Chacobo Indians Journal of Ethnopharmacology 69 2000 127 137
11. K Raynes M Foley L Tilley L Deady Novel bisquinoline antimalarials Biochemical Pharmacology 52 1996 551 559
12. P.I Trigg A.V Kondrachine The current global malaria situation I.W Sherman Malaria: Parasite, Biology, Pathogenesis and Protection 1998 ASM Washington, DC