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Volumn 74, Issue 1, 2006, Pages 602-614

Iron and pH homeostasis intersect at the level of fur regulation in the gastric pathogen Helicobacter pylori

Author keywords

[No Author keywords available]

Indexed keywords

FUR PROTEIN; IRON; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 29644439241     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.74.1.602-614.2006     Document Type: Article
Times cited : (115)

References (57)
  • 1
    • 0034858331 scopus 로고    scopus 로고
    • Characterization of the low-pH responses of Helicobacter pylori using genomic DNA arrays
    • Allan, E., C. L. Clayton, A. McLaren, D. M. Wallace, and B. W. Wren. 2001. Characterization of the low-pH responses of Helicobacter pylori using genomic DNA arrays. Microbiology 147:2285-2292.
    • (2001) Microbiology , vol.147 , pp. 2285-2292
    • Allan, E.1    Clayton, C.L.2    McLaren, A.3    Wallace, D.M.4    Wren, B.W.5
  • 2
    • 0028884177 scopus 로고
    • Precise gene disruption in Saccharomyces cerevisiae by double fusion polymerase chain reaction
    • Amberg, D. C., D. Botstein, and E. M. Beasley. 1995. Precise gene disruption in Saccharomyces cerevisiae by double fusion polymerase chain reaction. Yeast 11:1275-1280.
    • (1995) Yeast , vol.11 , pp. 1275-1280
    • Amberg, D.C.1    Botstein, D.2    Beasley, E.M.3
  • 3
    • 0035117352 scopus 로고    scopus 로고
    • Acid-induced gene expression in Helicobacter pylori: Study in genomic scale by microarray
    • Ang, S., C. Z. Lee, K. Peck, M. Sindici, U. Matrubutham, M. A. Gleeson, and J. T. Wang. 2001. Acid-induced gene expression in Helicobacter pylori: study in genomic scale by microarray. Infect. Immun. 69:1679-1686.
    • (2001) Infect. Immun. , vol.69 , pp. 1679-1686
    • Ang, S.1    Lee, C.Z.2    Peck, K.3    Sindici, M.4    Matrubutham, U.5    Gleeson, M.A.6    Wang, J.T.7
  • 5
    • 0033759351 scopus 로고    scopus 로고
    • Regulation of ferritin-mediated cytoplasmic iron storage by the ferric uptake regulator homolog (Fur) of Helicobacter pylori
    • Bereswill, S., S. Greiner, A. H. van Vliet, B. Waidner, F. Fassbinder, E. Schiltz, J. G. Kusters, and M. Kist. 2000. Regulation of ferritin-mediated cytoplasmic iron storage by the ferric uptake regulator homolog (Fur) of Helicobacter pylori. J. Bacteriol. 182:5948-5953.
    • (2000) J. Bacteriol. , vol.182 , pp. 5948-5953
    • Bereswill, S.1    Greiner, S.2    Van Vliet, A.H.3    Waidner, B.4    Fassbinder, F.5    Schiltz, E.6    Kusters, J.G.7    Kist, M.8
  • 7
    • 0025038013 scopus 로고
    • Epidemiology and pathophysiology of Campylobacter pylori infections
    • Blaser, M. J. 1990. Epidemiology and pathophysiology of Campylobacter pylori infections. Rev. Infect. Dis. 12(Suppl. 1):S99-S106.
    • (1990) Rev. Infect. Dis. , vol.12 , Issue.SUPPL. 1
    • Blaser, M.J.1
  • 8
    • 0032537288 scopus 로고    scopus 로고
    • Helicobacter pylon and gastric diseases
    • Blaser, M. J. 1998. Helicobacter pylon and gastric diseases. BMJ 316:1507-1510.
    • (1998) BMJ , vol.316 , pp. 1507-1510
    • Blaser, M.J.1
  • 9
    • 3242881125 scopus 로고    scopus 로고
    • Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori
    • Bury-Mone, S., J. M. Thiberge, M. Contreras, A. Maitournam, A. Labigne, and H. De Reuse. 2004. Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori. Mol. Microbiol. 53:623-638.
    • (2004) Mol. Microbiol. , vol.53 , pp. 623-638
    • Bury-Mone, S.1    Thiberge, J.M.2    Contreras, M.3    Maitournam, A.4    Labigne, A.5    De Reuse, H.6
  • 10
  • 11
    • 0042065267 scopus 로고    scopus 로고
    • Characterization of the roles of NikR, a nickel-responsive pleiotropic autoregulator of Helicobacter pylori
    • Contreras, M., J. M. Thiberge, M. A. Mandrand-Berthelot, and A. Labigne. 2003. Characterization of the roles of NikR, a nickel-responsive pleiotropic autoregulator of Helicobacter pylori. Mol. Microbiol. 49:947-963.
    • (2003) Mol. Microbiol. , vol.49 , pp. 947-963
    • Contreras, M.1    Thiberge, J.M.2    Mandrand-Berthelot, M.A.3    Labigne, A.4
  • 13
    • 0034902772 scopus 로고    scopus 로고
    • Iron-dependent transcription of the frpB gene of Helicobacter pylori is controlled by the fur repressor protein
    • Delany, I., A. B. Pacheco, G. Spohn, R. Rappuoli, and V. Scarlato. 2001. Iron-dependent transcription of the frpB gene of Helicobacter pylori is controlled by the Fur repressor protein. J. Bacteriol. 183:4932-4937.
    • (2001) J. Bacteriol. , vol.183 , pp. 4932-4937
    • Delany, I.1    Pacheco, A.B.2    Spohn, G.3    Rappuoli, R.4    Scarlato, V.5
  • 14
    • 0036436311 scopus 로고    scopus 로고
    • Autoregulation of Helicobacter pylori fur revealed by functional analysis of the iron-binding site
    • Delany, I., G. Spohn, A. B. Pacheco, R. Ieva, C. Alaimo, R. Rappuoli, and V. Scarlato. 2002. Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron-binding site. Mol. Microbiol. 46:1107-1122.
    • (2002) Mol. Microbiol. , vol.46 , pp. 1107-1122
    • Delany, I.1    Spohn, G.2    Pacheco, A.B.3    Ieva, R.4    Alaimo, C.5    Rappuoli, R.6    Scarlato, V.7
  • 15
    • 0035724513 scopus 로고    scopus 로고
    • The fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pylori
    • Delany, I., G. Spohn, R. Rappuoli, and V. Scarlato. 2001. The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pylori. Mol. Microbiol. 42:1297-1309.
    • (2001) Mol. Microbiol. , vol.42 , pp. 1297-1309
    • Delany, I.1    Spohn, G.2    Rappuoli, R.3    Scarlato, V.4
  • 16
    • 0026331068 scopus 로고
    • Formation and resolution of recombination intermediates by Escherichia coli RecA and RuvC proteins
    • Dunderdale, H. J., F. E. Benson, C. A. Parsons, G. J. Sharples, R. G. Lloyd, and S. C. West. 1991. Formation and resolution of recombination intermediates by Escherichia coli RecA and RuvC proteins. Nature 354:506-510.
    • (1991) Nature , vol.354 , pp. 506-510
    • Dunderdale, H.J.1    Benson, F.E.2    Parsons, C.A.3    Sharples, G.J.4    Lloyd, R.G.5    West, S.C.6
  • 20
    • 0042932364 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation
    • Gebert, B., W. Fischer, E. Weiss, R. Hoffmann, and R. Haas. 2003. Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation. Science 301:1099-1102.
    • (2003) Science , vol.301 , pp. 1099-1102
    • Gebert, B.1    Fischer, W.2    Weiss, E.3    Hoffmann, R.4    Haas, R.5
  • 21
    • 0026064725 scopus 로고
    • Escherichia coli RuvC protein is an endonuclease that resolves the Holliday structure
    • Iwasaki, H., M. Takahagi, T. Shiba, A. Nakata, and H. Shinagawa. 1991. Escherichia coli RuvC protein is an endonuclease that resolves the Holliday structure. EMBO J. 10:4381-4389.
    • (1991) EMBO J. , vol.10 , pp. 4381-4389
    • Iwasaki, H.1    Takahagi, M.2    Shiba, T.3    Nakata, A.4    Shinagawa, H.5
  • 22
  • 23
    • 0023917709 scopus 로고
    • Gene disruption and replacement as a feasible approach for mutagenesis of Campylobacter jejuni
    • Labigne-Roussel, A., P. Courcoux, and L. Torapkins. 1988. Gene disruption and replacement as a feasible approach for mutagenesis of Campylobacter jejuni. J. Bacteriol. 170:1704-1708.
    • (1988) J. Bacteriol. , vol.170 , pp. 1704-1708
    • Labigne-Roussel, A.1    Courcoux, P.2    Torapkins, L.3
  • 24
    • 3042777261 scopus 로고    scopus 로고
    • Proteomic analysis of a ferric uptake regulator mutant of Helicobacterpylori: Regulation of Helicobacter pylori gene expression by ferric uptake regulator and iron
    • Lee, H. W., Y. H. Choe, D. K. Kim, S. Y. Jung, and N. G. Lee. 2004. Proteomic analysis of a ferric uptake regulator mutant of Helicobacterpylori: regulation of Helicobacter pylori gene expression by ferric uptake regulator and iron. Proteomics 4:2014-2027.
    • (2004) Proteomics , vol.4 , pp. 2014-2027
    • Lee, H.W.1    Choe, Y.H.2    Kim, D.K.3    Jung, S.Y.4    Lee, N.G.5
  • 25
    • 0037378144 scopus 로고    scopus 로고
    • Helicobacter pylori mutants defective in RuvC Holliday junction resolvase display reduced macrophage survival and spontaneous clearance from the murine gastric mucosa
    • Loughlin, M. F., F. M. Barnard, D. Jenkins, G. J. Sharples, and P. J. Jenks. 2003. Helicobacter pylori mutants defective in RuvC Holliday junction resolvase display reduced macrophage survival and spontaneous clearance from the murine gastric mucosa. Infect. Immun. 71:2022-2031.
    • (2003) Infect. Immun. , vol.71 , pp. 2022-2031
    • Loughlin, M.F.1    Barnard, F.M.2    Jenkins, D.3    Sharples, G.J.4    Jenks, P.J.5
  • 26
    • 0032696916 scopus 로고    scopus 로고
    • Helicobacter pylon rocF is required for arginase activity and acid protection in vitro but is not essential for colonization of mice or for urease activity
    • McGee, D. J., F. J. Radcliff, G. L. Mendz, R. L. Ferrero, and H. L. Mobley. 1999. Helicobacter pylon rocF is required for arginase activity and acid protection in vitro but is not essential for colonization of mice or for urease activity. J. Bacteriol. 181:7314-7322.
    • (1999) J. Bacteriol. , vol.181 , pp. 7314-7322
    • McGee, D.J.1    Radcliff, F.J.2    Mendz, G.L.3    Ferrero, R.L.4    Mobley, H.L.5
  • 27
    • 0030611407 scopus 로고    scopus 로고
    • Analysis of F1F0-ATPase from Helicobacter pylori
    • McGowan, C. C., T. L. Cover, and M. J. Blaser. 1997. Analysis of F1F0-ATPase from Helicobacter pylori. Infect. Immun. 65:2640-2647.
    • (1997) Infect. Immun. , vol.65 , pp. 2640-2647
    • McGowan, C.C.1    Cover, T.L.2    Blaser, M.J.3
  • 29
    • 0038460080 scopus 로고    scopus 로고
    • Promoter analysis of Helicobacter pylori genes with enhanced expression at low pH
    • McGowan, C. C., A. S. Necheva, M. H. Forsyth, T. L. Cover, and M. J. Blaser. 2003. Promoter analysis of Helicobacter pylori genes with enhanced expression at low pH. Mol. Microbiol. 48:1225-1239.
    • (2003) Mol. Microbiol. , vol.48 , pp. 1225-1239
    • McGowan, C.C.1    Necheva, A.S.2    Forsyth, M.H.3    Cover, T.L.4    Blaser, M.J.5
  • 30
    • 0032704187 scopus 로고    scopus 로고
    • The cadA gene of Vibrio choleras is induced during infection and plays a role in acid tolerance
    • Merrell, D. S., and A. Camilli. 1999. The cadA gene of Vibrio choleras is induced during infection and plays a role in acid tolerance. Mol. Microbiol. 34:836-849.
    • (1999) Mol. Microbiol. , vol.34 , pp. 836-849
    • Merrell, D.S.1    Camilli, A.2
  • 31
    • 4944261520 scopus 로고    scopus 로고
    • Expression profiling in Helicobacter pylon infection
    • K. Appasani (ed.). Eaton Publishing, Westborough, United Kingdom
    • Merrell, D. S., and S. Falkow. 2003. Expression profiling in Helicobacter pylon infection, p. 273-303. In K. Appasani (ed.), Perspectives in gene expression. Eaton Publishing, Westborough, United Kingdom.
    • (2003) Perspectives in Gene Expression , pp. 273-303
    • Merrell, D.S.1    Falkow, S.2
  • 32
    • 0038781648 scopus 로고    scopus 로고
    • pH-regulated gene expression of the gastric pathogen Helicobacter pylori
    • Merrell, D. S., M. L. Goodrich, G. Otto, L. S. Tompkins, and S. Falkow. 2003. pH-regulated gene expression of the gastric pathogen Helicobacter pylori. Infect. Immun. 71:3529-3539.
    • (2003) Infect. Immun. , vol.71 , pp. 3529-3539
    • Merrell, D.S.1    Goodrich, M.L.2    Otto, G.3    Tompkins, L.S.4    Falkow, S.5
  • 37
    • 0033566727 scopus 로고    scopus 로고
    • Conservation, localization, and expression of HopZ, a protein involved in adhesion of Helicobacter pylori
    • Peck, B., M. Ortkamp, K. D. Diehl, E. Hundt, and B. Knapp. 1999. Conservation, localization, and expression of HopZ, a protein involved in adhesion of Helicobacter pylori. Nucleic Acids Res. 27:3325-3333.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 3325-3333
    • Peck, B.1    Ortkamp, M.2    Diehl, K.D.3    Hundt, E.4    Knapp, B.5
  • 38
    • 0031738385 scopus 로고    scopus 로고
    • Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome
    • Peek, R. M., Jr., S. A. Thompson, J. P. Donahue, K. T. Tham, J. C. Atherton, M. J. Blaser, and G. G. Miller. 1998. Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome. Proc. Assoc. Am. Physicians 110:531-544.
    • (1998) Proc. Assoc. Am. Physicians , vol.110 , pp. 531-544
    • Peek Jr., R.M.1    Thompson, S.A.2    Donahue, J.P.3    Tham, K.T.4    Atherton, J.C.5    Blaser, M.J.6    Miller, G.G.7
  • 39
    • 1942502327 scopus 로고    scopus 로고
    • Genetic evidence for histidine kinase HP165 being an acid sensor of Helicobacter pylori
    • Pflock, M., P. Dietz, J. Schar, and D. Beier. 2004. Genetic evidence for histidine kinase HP165 being an acid sensor of Helicobacter pylori. FEMS Microbiol. Lett. 234:51-61.
    • (2004) FEMS Microbiol. Lett. , vol.234 , pp. 51-61
    • Pflock, M.1    Dietz, P.2    Schar, J.3    Beier, D.4
  • 40
    • 0023215922 scopus 로고
    • pH of the microclimate lining human gastric and duodenal mucosa in vivo: Studies in control subjects and in duodenal ulcer patients
    • Quigley, E. M., and L. A. Turnberg. 1987. pH of the microclimate lining human gastric and duodenal mucosa in vivo: studies in control subjects and in duodenal ulcer patients. Gastroenterology 92:1876-1884.
    • (1987) Gastroenterology , vol.92 , pp. 1876-1884
    • Quigley, E.M.1    Turnberg, L.A.2
  • 41
    • 33745158157 scopus 로고
    • A simple method of estimating fifty per cent endpoints
    • Reed, L. J., and H. Muench. 1938. A simple method of estimating fifty per cent endpoints. Am. J. Hyg. 27:493-497.
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 43
    • 0035145673 scopus 로고    scopus 로고
    • Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infection
    • Salama, N. R., G. Otto, L. Tompkins, and S. Falkow. 2001. Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infection. Infect. Immun. 69:730-736.
    • (2001) Infect. Immun. , vol.69 , pp. 730-736
    • Salama, N.R.1    Otto, G.2    Tompkins, L.3    Falkow, S.4
  • 44
    • 9244239747 scopus 로고    scopus 로고
    • Global transposon mutagenesis and essential gene analysis of Helicobacter pylori
    • Salama, N. R., B. Shepherd, and S. Falkow. 2004. Global transposon mutagenesis and essential gene analysis of Helicobacter pylori. J. Bacteriol. 186:7926-7935.
    • (2004) J. Bacteriol. , vol.186 , pp. 7926-7935
    • Salama, N.R.1    Shepherd, B.2    Falkow, S.3
  • 46
    • 2442682964 scopus 로고    scopus 로고
    • Inhibition of primary human T-cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion
    • Sundrud, M. S., V. J. Torres, D. Unutmaz, and T. L. Cover. 2004. Inhibition of primary human T-cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proc. Natl. Acad. Sci. USA 101:7727-7732.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 7727-7732
    • Sundrud, M.S.1    Torres, V.J.2    Unutmaz, D.3    Cover, T.L.4
  • 47
    • 0032774326 scopus 로고    scopus 로고
    • Regulation of the transcription of genes encoding different virulence factors in Helicobacter pylori by free iron
    • Szczebara, F., L. Dhaenens, S. Armand, and M. O. Husson. 1999. Regulation of the transcription of genes encoding different virulence factors in Helicobacter pylori by free iron. FEMS Microbiol. Lett. 175:165-170.
    • (1999) FEMS Microbiol. Lett. , vol.175 , pp. 165-170
    • Szczebara, F.1    Dhaenens, L.2    Armand, S.3    Husson, M.O.4
  • 48
    • 0242417000 scopus 로고    scopus 로고
    • Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression
    • Thompson, L. J., D. S. Merrell, B. A. Neilan, H. Mitchell, A. Lee, and S. Falkow. 2003. Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression. Infect. Immun. 71:2643-2655.
    • (2003) Infect. Immun. , vol.71 , pp. 2643-2655
    • Thompson, L.J.1    Merrell, D.S.2    Neilan, B.A.3    Mitchell, H.4    Lee, A.5    Falkow, S.6
  • 49
    • 0029066974 scopus 로고
    • Isolation of the Helicobacter pylori recA gene and involvement of the recA region in resistance to low pH
    • Thompson, S. A., and M. J. Blaser. 1995. Isolation of the Helicobacter pylori recA gene and involvement of the recA region in resistance to low pH. Infect. Immun. 63:2185-2193.
    • (1995) Infect. Immun. , vol.63 , pp. 2185-2193
    • Thompson, S.A.1    Blaser, M.J.2
  • 51
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher, V. G., R. Tibshirani, and G. Chu. 2001. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98:5116-5121.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 52
    • 0842305636 scopus 로고    scopus 로고
    • Acid-responsive gene induction of ammonia-producing enzymes in Helicobacter pylori is mediated via a metal-responsive repressor cascade
    • van Vliet, A. H., E. J. Kuipers, J. Stoof, S. W. Poppelaars, and J. G. Kusters. 2004. Acid-responsive gene induction of ammonia-producing enzymes in Helicobacter pylori is mediated via a metal-responsive repressor cascade. Infect. Immun. 72:766-773.
    • (2004) Infect. Immun. , vol.72 , pp. 766-773
    • Vliet, A.H.1    Kuipers, E.J.2    Stoof, J.3    Poppelaars, S.W.4    Kusters, J.G.5
  • 53
    • 0037646546 scopus 로고    scopus 로고
    • Differential regulation of amidase- and formamidase-mediated ammonia production by the Helicobacter pylori fur repressor
    • van Vliet, A. H., J. Stoof, S. W. Poppelaars, S. Bereswill, G. Homuth, M. Kist, E. J. Kuipers, and J. G. Kusters. 2003. Differential regulation of amidase- and formamidase-mediated ammonia production by the Helicobacter pylori fur repressor. J. Biol. Chem. 278:9052-9057.
    • (2003) J. Biol. Chem. , vol.278 , pp. 9052-9057
    • Van Vliet, A.H.1    Stoof, J.2    Poppelaars, S.W.3    Bereswill, S.4    Homuth, G.5    Kist, M.6    Kuipers, E.J.7    Kusters, J.G.8
  • 56
    • 0036889319 scopus 로고    scopus 로고
    • Identification by RNA profiling and mutational analysis of the novel copper resistance determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori
    • Waidner, B., K. Melchers, I. Ivanov, H. Loferer, K. W. Bensch, M. Kist, and S. Bereswill. 2002. Identification by RNA profiling and mutational analysis of the novel copper resistance determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori. J. Bacteriol. 184:6700-6708.
    • (2002) J. Bacteriol. , vol.184 , pp. 6700-6708
    • Waidner, B.1    Melchers, K.2    Ivanov, I.3    Loferer, H.4    Bensch, K.W.5    Kist, M.6    Bereswill, S.7


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