Regulation of the transcription of genes encoding different virulence factors in Helicobacter pylori by free iron

FEMS Microbiology Letters

Volumn 175, Issue 2, 1999, Pages 165-170

  Szczebara, F ^a   Dhaenens, L ^a   Armand, S ^a   Husson, M O ^a  

^a UNIV LILLE   (France)

Author keywords

Fur protein; H. pylori; Iron regulation; Virulence factor

Indexed keywords

IRON; VIRULENCE FACTOR;

ARTICLE; BACTERIAL GROWTH; BACTERIUM CULTURE; CULTURE MEDIUM; GEL ELECTROPHORESIS; GENE EXPRESSION REGULATION; GROWTH CURVE; HELICOBACTER PYLORI; NORTHERN BLOTTING; PRIORITY JOURNAL; RNA ANALYSIS;

HELICOBACTER PYLORI;

EID: 0032774326     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(99)00188-3     Document Type: Article

References (22)

1. Cover, T.L. and Blaser, M.J. (1996) Helicobacter pylori infection, a paradigm for chronic mucosal inflammation: pathogenesis and implication for eradication and prevention. Adv. Int. Med. 41, 85-117.
2. Labigne, A. and de Reuse, H. (1996) Determinants of Helicobacter pylori pathogenicity. Infect. Agents Dis. 5, 191-202.
3. Karita, M., Tummuru, M.R., Wirth, H.P. and Blaser, M.J. (1996) Effect of growth phase and acid shock on Helicobacter pylori cagA expression. Infect. Immun. 64, 4501-4507.
4. Baverfeind, P., Garner, R., Dunn, B.E. and Mobley, H.L.T. (1997) Synthesis and activity of Helicobacter pylori urease and catalase at low pH. Gut 40, 25-30.
5. Litwin, C.M. and Calderwood, S.B. (1993). Role of iron in regulation of virulence genes. Clin. Microb. Rev. 6, 137-149.
6. Stoebner, J.A. and Payne, S.M. (1988) Iron-regulated hemolysin production, and utilization of heme and hemoglobin by Vibrio cholerae. Infect. Immun. 56, 2891-2895.
7. Kaczorek, M., Zettlmeissi, G., Delpeyroux, F. and Streeck, R.E. (1985) Diphtheria toxin promotor function in Corynebacterium diphtheriae and Escherichia coli. Nucleic Acids Res. 13, 3147-3159.
8. Husson, M.O., Legrand, D., Spick, G. and Leclerc, H. (1993) Iron acquisition by Helicobacter pylori: importance of human lactoferrin. Infect. Immun. 61, 2694-2697.
9. Worst, D.J., Otto, B.R. and de Graff, J. (1995) Iron-repressible outer membrane proteins of Helicobacter pylori involved in heme uptake.
10. Dhaenens, L., Szczebara, F. and Husson, M.O. (1997) Identification, characterization, and immunogenicity of the lactoferrin-binding protein from Helicobacter pylori. Infect. Immun. 65, 514-518.
11. Bereswill, S., Litche, F., Vey, T., Fassbinder, F. and Kist, M. (1998) Cloning and characterization of the fur gene from Helicobacter pylori. FEMS Microbiol. Lett. 159, 193-200.
12. Worst, D.J., Sparrius, M., Kuipers, E.J., Kusters, J.G. and de Graff, J. (1996) Human serum antibody response against iron-repressible outer membrane proteins of H. pylori. FEMS Microbiol. Lett. 144, 29-32.
13. Maniatis, T., Fritsch, E.F. and Sambrook, J. (1989) Molecular Cloning: A Laboratory Manual, 2nd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
14. Lindholm, C., Ojek, J. and Svennerholm, A.M. (1997) Quantification of conserved antigens in Helicobacter pylori during different culture conditions. Infect. Immun. 65, 5376-5380.
15. Saito, T. and Williams, R.J.P. (1991) The binding of the ferric uptake regulation protein to a DNA fragment. Eur. J. Biochem. 197, 43-47.
16. Bereswill, S., Waidner, U., Obenbreit, S., Litche, F., Fassbinder, F., Bode, G. and Kist, M. Structural, functional and mutational analysis of the pfr gene encoding a ferritin from Helicobacter pylori. Microbiology 144, 2505-2516.
17. Tomb, J.F. et al. (1997) The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388, 539-547.
18. Ochsner, U.A., Johnson, Z., Lamont, I.L., Cunliffe, H.E. and Vasil, M.L. (1996) ExotoxinA production in Pseudomonas aeruginosa required the iron-regulated pvdS gene encoding an alternative sigma factor. Mol. Biol. 21, 1019-1028.
19. Schmitt, W. and Haas, R. (1994) Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein. Mol. Microbiol. 12, 307-319.
20. Lage, A.P., Godefroid, E., Fauconnier, A., Burette, A., Butzler, J.-P., Bollen, A. and Glupczynski, Y. (1995) Diagnosis of H. pylori infection by PCR: comparison with other invasive techniques and detection of cagA gene in gastric biopsy specimen. J. Clin. Microbiol. 33, 2752-2756.
21. Clayton, C.L., Kleanthous, H., Coates, P.J., Morgan, D.D. and Tabaqchali, S. (1992) Sensitive detection of H. pylori by using PCR. J. Clin. Microbiol. 30, 192-200.
22. Szczebara, F., Dhaenens, L., Vincent, P. and Husson, M.O. (1997) Evaluation of rapid molecular methods for detection of clarithromycin resistance in H. pylori. Eur. J. Clin. Microbiol. Infect. Dis. 16, 162-164.