Cloning of a human 'epidermal-type' 12-lipoxygenase-related gene and chromosomal localization to 17p13

Cytogenetics and Cell Genetics

Volumn 81, Issue 1, 1998, Pages 79-82

  Sun, D ^a   Elsea, S H ^b   Patel, P I ^b   Funk, Colin D ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; COMPLEMENTARY DNA;

ARTICLE; CHROMOSOME 17P; DNA PROBE; EPIDERMIS; EXON; HAIR FOLLICLE; HUMAN; HUMAN TISSUE; INTRON; MOLECULAR CLONING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOGENE; SEQUENCE HOMOLOGY; SKIN;

MURINAE; SIGANUS;

EID: 0031824787     PISSN: 03010171     EISSN: None     Source Type: Journal    
DOI: 10.1159/000014993     Document Type: Article

References (10)

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2. Funk CD, Furci L, FitzGerald GA: Molecular cloning, primary structure and expression of the human platelet/erythroleukemia cell 12-lipoxygenase. Proc natl Acad Sci, USA 87:5638-5642 (1990).
3. Funk CD, Funk LB, FitzGerald GA, Samuelsson B: Characterization of two human 12-lipoxygenase genes. Proc natl Acad Sci, USA 89:3962-3966 (1992).
4. Funk CD, Keeney DS, Oliw EH, Boeglin WE, Brash AR: Functional expression and cellular localization of a mouse epidermal lipoxygenase. J biol Chem 271:23338-23344 (1996).
5. Patel PI, Roa BB, Welcher AA, Schoener-Scott R, Trask BJ, Pentao L, Snipes GJ, Garcia CA, Francke U, Shooter EM, et al.: The gene for the peripheral myelin protein PMP-22 is a candidate for Charcot-Marie-Tooth disease type IA. Nature Genet 1:159-165 (1992).
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7. Sigal E, Craik CS, Highland E, Grunberger D, Costello LL, Dixon RAF, Nadel JA: Molecular cloning and primary structure of human 15-lipoxygenase cDNA. Biochem biophys Res Commun 157:457- 464 (1988).
8. Sun D-X, Funk CD: Disruption of 12/15-lipoxygenase expression in peritoneal macrophages: enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of LDL. J biol Chem 271:24055-24062 (1996).
9. van Tuinen P, Rich DC, Summers KM, Ledbetter DH: Regional mapping panel for human chromosome 17: application to neurofibromatosis type 1. Genomics 1:374-381 (1987).
10. van Tuinen P, Dobyns WB, Rich DC, Summers KM, Robinson TJ, Nakamura Y, Ledbetter DH: Molecular detection of microscopic and submicroscopic deletions associated with Miller-Dieker syndrome. Am J hum Genet 43:587-596 (1988).