Altered expression of secreted Frizzled-related protein-2 in retinitis pigmentosa retinas

Investigative Ophthalmology and Visual Science

Volumn 41, Issue 6, 2000, Pages 1297-1301

  Jones, Stephen E ^a,b   Jomary, Catherine ^a   Grist, John ^a   Stewart, Hannah J ^a   Neal, Michael J ^a  

^a Rayne Institute ^*  (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; COMPLEMENTARY DNA; GENE PRODUCT; RNA;

ADULT; AGED; APOPTOSIS; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINITIS PIGMENTOSA;

AGED; BLOTTING, NORTHERN; DNA PRIMERS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PROTEIN BIOSYNTHESIS; PROTEINS; RETINITIS PIGMENTOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 0034014073     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Wong P. Apoptosis, retinitis pigmentosa, and degeneration. Biochem Cell Biol. 1994;72:489-498.
2. Inglehearn CF. Molecular genetics of human retinal dystrophies. Eye. 1998;12:571-579.
3. Jones SE, Meerabux JMA, Yeats DA, Neal MJ. Analysis of differentially expressed genes in retinitis pigmentosa retinas: altered expression of clusterin mRNA. FEBS Lett. 1992;300:279-282.
4. Chang G-Q, Hao Y, Wong F. Apoptosis: final common pathway of photoreceptor death in rd, rds and rhodopsin mutant mice. Neuron. 1993;11:595-605.
5. Portera-Cailliau C, Sung C-H, Nathans J, Adler R. Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa. Proc Natl Acad Sci USA. 1994;91:974-978.
6. Lolley RN, Rong H, Craft CM. Linkage of photoreceptor degeneration by apoptosis with inherited defect in phototransduction. Invest Ophthalmol Vis Sci. 1994;35:358-362.
7. Chen J, Flannery JG, LaVail MM, Steinberg RH, Xu J, Simon MI. Bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations. Proc Natl Acad Sci USA. 1996;93:7042-7047.
8. L transgenes and photoreceptor degeneration. Invest Ophthalmol Vis Sci. 1996;37: 2434-2446.
9. Ali RR, Reichel MB, Kanuga N, et al. Absence of p53 delays apoptotic photoreceptor cell death in the rds mouse. Curr Eye Res. 1998;17:917-923.
10. Mosinger Ogilvie J, Deckwerth TL, Knudson CM, Korsmeyer SJ. Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-dencient mice. Invest Ophthalmol Vis Sci. 1998;39:1713-1720.
11. Tokunaga K, Nakamura Y, Sakata K, et al. Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res. 1994;47:5616-5619.
12. Robinson G, Ellis IO, MacLennan KA. Immunocytochemistry. In: Bancroft JD, Stevens A, eds. Theory and Practice of Histological Techniques. 3rd ed. Edinburgh: Churchill Livingstone; 1990:413-436.
13. Melkonyan HS, Chang WC, Shapiro JP, et al. SARPs: a family of secreted apoptosis-related proteins. Proc Natl Acad Sci USA. 1997; 94:13636-13641.
14. Rattner A, Hsieh JC, Smallwood PM, et al. A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci USA. 1997;94: 2859-2863.
15. Shirozu M, Tada H, Tashiro K, et al. Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. Genomics. 1996;37:273-280.
16. Nusse R. FRP/FrzB genes and interactions with Wnts. 1999; .
17. Dale TC. Signal transduction by the Wnt family of ligands. Biochem J. 1998;329:209-223.
18. Martinez-Arias A, Brown AMC, Brennan K. Wnt signalling: pathway or network? Curr Opin Genet Dev. 1999;9:447-454.
19. Bafico A, Gazit A, Pramila T, Finch PW, Yaniv A, Aaronson SA. Interaction of frizzled related protein (FRP) with wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of wnt signaling. J Biol Chem. 1999;274:16180-16187.
20. Chang JT, Esumi N, Moore K, et al. Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium. Hum Mol Genet. 1999;8:575-583.
21. Zhou Z, Wang J, Han X, Zhou J, Linder S. Up-regulation of human secreted frizzled homolog in apoptosis and its down-regulation in breast tumors. Int J Cancer. 1998;78:95-99.
22. Wolf V, Ke G, Dharmarajan AM, et al. DDC-4, an apoptosis-associated gene, is a secreted frizzled relative. FEBS Lett. 1997;417:385-389.