That impish TIMP: The tissue inhibitor of metalloproteinases-3

Journal of Clinical Investigation

Volumn 108, Issue 6, 2001, Pages 799-800

  Woessner J F , Jr ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TISSUE INHIBITOR OF METALLOPROTEINASE 3;

AMINO ACID SUBSTITUTION; APOPTOSIS; GENE OVEREXPRESSION; GENE REPRESSION; MOUSE; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN;

ANIMALS; APOPTOSIS; EXTRACELLULAR MATRIX; HUMANS; MICE; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-3;

EID: 0034836937     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200113709     Document Type: Note

References (23)

1. Integrin signaling
2. Cell surface heparan sulfate proteoglycans: Selective regulators of ligand-receptor encounters
3. Proteolysis and cell migration: Creating a path?
4. Matrix metalloproteinases
5. Tissue inhibitors of metalloproteinases: Evolution, structure and function
6. Tissue inhibitors of metalloproteinases: Structure, regulation and biological function
7. Characterization of a transformation-sensitive protein in the extracellular matrix of chicken embryo fibroblasts
8. TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix
9. TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3
10. The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3
11. ADAM 12-S cleaves IGFBP3 and IGFBP-5 and is inhibited by TIMP-3
12. Human myeloma cells shed the interleukin-6 receptor: Inhibition by tissue inhibitor of metalloproteinase-3 and a hydroxamate-based metalloproteinase inhibitor
13. Tissue inhibitor of metalloproteinases-3 inhibits shedding of L-selectin from leukocytes
14. Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase
15. TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TSS)
16. A novel Ser 156Cys mutation in the tissue inhibitor of metalloproteinases-3 (TIMP3) in Sorsby's fundus dystrophy with unusual clinical features
17. Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells
18. Divergent effects of tissue inhibitor o f metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro: TIMP-3 promotes apoptosis
19. TIMP-3 induces cell death by stabilizing TNF-alpha receptors on the surface of human colon carcinoma cells
20. Localization of the death domain of tissue inhibitor of metalloproteinase-3 to the N terminus: Metalloproteinase inhibition is associated with proapoptotic activity
21. Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor o f metalloproteinases-3 (TIMP-3)
22. Accelerated apoptosis in the Timp-3-deficient mammary gland
23. Two distinct phases of apoptosis in mammary gland involution: Proteinase-independent and dependent pathways