Oncostatin M up-regulates tissue inhibitor of metalloproteinases-3 gene expression in articular chondrocytes viade novo transcription, protein synthesis, and tyrosine kinase- and mitogen-activated protein kinase- dependent mechanisms

Journal of Immunology

Volumn 161, Issue 9, 1998, Pages 5000-5007

  Li, Wen Qing ^a   Zafarullah, Muhammad ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYTOKINE; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; ONCOSTATIN M; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ANIMAL CELL; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE MATRIX; CATTLE; ENZYME DEGRADATION; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GENETIC REGULATION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; RECEPTOR UPREGULATION; TISSUE METABOLISM;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, RHEUMATOID; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARTILAGE, ARTICULAR; CATTLE; CELLS, CULTURED; DACTINOMYCIN; DEXAMETHASONE; FLAVONOIDS; GENE EXPRESSION REGULATION; NUCLEIC ACID SYNTHESIS INHIBITORS; ONCOSTATIN M; PEPTIDES; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; STIMULATION, CHEMICAL; TISSUE INHIBITOR OF METALLOPROTEINASE-3; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 0001155860     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Hamerman D. Clinical implications of osteoarthritis and ageing. 1995. Ann. Rheum. Dis. 54:82.
2. Westacott, C. I., and M. Sharif. 1996. Cytokines in osteoarthritis: mediators or markers of joint destruction? Semin. Arthritis Rheum. 25:254.
3. Poole, A. R. 1994. Immunological markers of joint inflammation, skeletal damage and repair: where are we now? Ann. Rheum. Dis. 53:3.
4. Birkedal-Hansen, H. 1995. Proteolytic remodeling of extracellular matrix. Cur. Opin. Cell Biol. 7:728.
5. Matrisian, L. M. 1992. The matrix-degrading metalloproteinases. BioEssays 14: 455.
6. Dochetry, A. J. P., A. Lyons, B. J. Smith, E. M. Wright, P. E. Stephens, T. J. R. Harris, G. Murphy, and J. J. Reynolds. 1985. Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature 318:66.
7. Stetler-Stevenson, W. G., H. C. Krutzsch, and L. A. Liotta. 1989. Tissue inhibitor of metalloproteinase (TIMP-2), a new member of the metalloproteinase inhibitor family. J. Biol. Chem. 264:17374.
8. Apte, S. S., M. G. Mattei, and B. R. Olsen. 1994. Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22. Genomics 19:86.
9. Greene, J., M. S. Wang, Y. E. Liu, L. A. Raymond, C. Rosen, and Y. E. Shi. 1996. Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4. J. Biol. Chem. 271:30375.
10. Dean D. D., J. Martel-Pelletier, J.-P. Pelletier, D. S. Howell, and J. F. Woessner, Jr. 1989 Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. J. Clin. Invest. 84:678.
11. Hayakawa, T., K. Yamashita, E. Ohuchi, and A. Shinagawa. 1994. Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2). J. Cell Sci. 107:2373.
12. Yamashita, K., M. Suzuki, H. Iwata, T. Koike, M. Hamaguchi, A. Shinagawa, T. Noguchi, and T. Hayakawa. 1996. Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2). FEBS Lett. 396:103.
13. Blenis, J., and S. P. Hawkes. 1983. Transformation-sensitive protein associated with the cell substratum of chicken embryo fibroblasts. Proc. Natl. Acad. Sci. USA 80:770.
14. Pavloff, N., P. W. Staskus, N. S. Kishnani, and S. P. Hawkes. 1992. A new inhibitor of metalloproteinases from chicken: ChIMP-3, a third member of the TIMP family. J. Biol. Chem. 267:17321.
15. Yang, T. T., and S. P. Hawkes. 1992. Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts. Proc. Natl. Acad. Sci. USA 89:10676.
16. Silbiger, S. M., V. L. Jacobsen, R. L. Cupples, and R. A. Koski. 1994. Cloning of cDNAs encoding human TIMP-3, a novel member of the tissue inhibitor of metalloproteinase family. Gene 141:293.
17. Uría, J. A., A. A. Ferrando, G. Velasco, J. M. P. Freije, and C. López-Otín. 1994. Structure and expression in breast tumors of human TIMP-3, a new member of the metalloproteinase inhibitor family. Cancer Res. 54:2091.
18. Leco, K. J., R. Khokha, N. Pavloff, S. P. Hawkes, and D. R. Edwards. 1994. Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues. J. Biol. Chem. 269:9352.
19. 1 progression, mitogenic stimulation, differentiation, and senescence. J. Biol. Chem. 269:18953.
20. Fariss, R. N., S. S. Apte, B. R. Olsen, K. Iwata, and A. H. Milam. 1997. Tissue inhibitor of metalloproteinases-3 is a component of Bruch's membrane of the eye. Am. J. Pathol. 150:323.
21. Weber, B. H. F., G. Vogt, R. C. Pruett, H. Stöhr, and U. Felbor. 1994. Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP-3) in patients with Sorsby's fundus dystrophy. Nat. Gen. 8:352.
22. Anande-Apte, B., M. S. Pepper, E. Voest, R. Montesano, B. Olsen, G. Murphy, S. S. Apte, and B. Zetter. 1997. Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3. Invest. Ophthalmol. Vis. Sci. 38:817.
23. Bian, J. H., Y. Wang, M. R. Smith, H. Kim, C. Jacobs, J. Jackman, H. F. Kung, N. H. Colburn, and Y. Sun. 1996. Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3. Carcinogenesis 17:1805.
24. Anande-Apte, B., L. Bao, R. Smith, K. Iwata, B. R. Olsen, B. Zetter, and S. S. Apte. 1996. A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth. Biochem. Cell Biol. 74:853.
25. Apte, S. S., B. R. Olsen, and G. Murphy. 1995. The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J. Biol. Chem. 270:14313.
26. Will, H., S. J. Atkinson, G. S. Butler, B. Smith, and G. Murphy. 1996. The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation-regulation by TIMP-2 and TIMP-3. J. Biol. Chem. 271:17119.
27. Apte, S. S., K. Hayashi, M. F. Seldin, M. G. Mattei, M. Hayashi, and B. R. Olsen. 1994. Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3. is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10. Dev. Dyn. 200:177.
28. Chin, J. R., and Z. Werb. 1997. Matrix metalloproteinases regulate morphogenesis, migration and remodeling of epithelium, tongue skeletal muscle and cartilage in the mandibular arch. Development 124:1519.
29. Su, S., F. Dehnade, and M. Zafarullah. 1996. Regulation of tissue inhibitor of metalloproteinases-3 gene expression by transforming growth factor β and dexamethasone in bovine and human articular chondrocytes. DNA Cell Biol. 15:1039.
30. Zafarullah, M., S. Su, J. Martel-Pelletier, J. A. DiBattista, B. G. Costello, W. G. Stetler-Stevenson, and J.-P. Pelletier. 1996. Tissue inhibitor of metalloproteinase-2 (TIMP-2) mRNA is constitutively expressed in bovine, human normal, and osteoarthritic articular chondrocytes. J. Cell. Biochem. 60:211.
31. Zarling, J. M., M. Shoyab, H. Marquardt, M. B. Hanson, M. N. Lioubin, and G. J. Todaro. 1986. Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells. Proc. Natl. Acad. Sci. USA 83:9793.
32. Rose, T. M., M. J. Lagrou, I. Fransson, B. Werelius, O. Delattre, G. Thomas, P. J. de Jong, G. J. Todaro, and J. P. Dumanski. 1993. The genes for oncostatin M (OSM) and leukemia inhibitory factor (LIF) are tightly linked on human chromosome 22. Genomics 17:136.
33. Hui, W., M. Bell, and G. Carroll. 1997. Detection of oncostatin M in synovial fluid from patients with rheumatoid arthritis. Ann. Rheum. Dis. 56:184.
34. Okamoto, H., M. Yamamura, Y. Monta, S. Harada, H. Makino, and Z. Ota. 1997. The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis. Arthritis Rheum. 40:1096.
35. Richards, C. D., M. Shoyab, T. J. Brown, and J. Gauldie. 1993. Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture. J. Immunol. 150:5596.
36. Hui, W., M. Bell, and G. Carroll. 1996. Oncostatin M (OSM) stimulates resorption and inhibits synthesis of proteoglycan in porcine articular cartilage explants. Cytokine 8:495.
37. Cawston, T. E., A. J. Ellis, G. Humm, E. Lean, D. Ward, and V. Curry. 1995. Interleukin-1 and oncostatin M in combination promote the release of collagen fragments from bovine nasal cartilage in culture. Biochem. Biophys. Res. Commun. 215:377.
38. Nemoto, O., H. Yamada, M. Mukaida, and M. Shimmei. 1996. Stimulation of TIMP-1 production by oncostatin M in human articular cartilage. Arthritis Rheum. 39:560.
39. Gastios, P., H. D. Haubeck, E. Van de Leur, W. Frisch, S. S. Apte, H. Greiling, P. C. Heinrich, and L. Graeve. 1996. Oncostatin M differentially regulates tissue inhibitors of metalloproteinases TIMP-1 and TIMP-3 gene expression in human synovial lining cells. Ear. J. Biochem. 241:56.
40. Muir, H. 1995 The chondrocyte, architect of cartilage: biomechanics, structure, function and molecular biology of cartilage matrix macromolecules. BioEssays 17:1039.
41. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156.
42. Zafarullah, M., J.-P. Pelletier, J. M. Cloutier, and J. Martel-Pelletier. 1993. Elevated metalloproteinase and tissue inhibitor of metalloproteinase mRNA in human osteoarthritic synovia. J. Rheumatol. 20:693.
43. Günther, M., H. D. Haubeck, E. Van de Leur, J. Bläser, S. Bender, I. Gütgemann, D.-C. Fischer, H. Tschesche, H. Greiling, P. C. Heinrich, and L. Graeve. 1994. Transforming growth factor β 1 regulates tissue inhibitor of metalloproteinases-1 expression in differentiated human articular chondrocytes. Arthritis Rheum. 37: 395.
44. Edwards, D. R., G. Murphy, J. J. Reynolds, S. E. Whitham, A. J. P. Docherty, P. Angel, and J. K. Heath. 1987. Transforming growth factor β modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J. 6:1899.
45. Dudley, D. T., L. Pang, S. J. Decker, A. J. Bridges, and A. R. Saltiel. 1995. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 92:7686.
46. Lotz, M., and P.-A. Gueme. 1991. Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TTMP-1/EPA). J. Biol. Chem. 266:2017.
47. Maier, R., V. Ganu, and M. Lotz. 1993. Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases. J. Biol. Chem. 268:21527.
48. Langdon, C., J. Leith, F. Smith, and C. D. Richards. 1997. Oncostatin M stimulates monocyte chemoattractant protein-1 and interleukin-1-induced matrix metalloproteinase-1 production by human synovial fibroblasts. Arthritis Rheum. 40: 2139.
49. Gueme, P.-A., D. A. Carson, and M. Lotz. 1990. IL-6 production by human articular chondrocytes: modulation of its synthesis by cytokines, growth factors, and hormones in vitro. J. Immunol. 144:499.
50. Lotz M., T. Moats, and P. M. Villiger. 1992. Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis. J. Clin. Invest. 90:888.
51. Verschure, P. J., L. A. Joosten, P. M. van der Kraan, and W. B. Van den Berg. 1994. Responsiveness of articular cartilage from normal and inflamed mouse knee joints to various growth factors. Ann. Rheum. Dis. 53:455.
52. Terada, S., E. Suzuki, H. Ueda, and F. Makishima. 1996. Cytokines involving gp130 in signal transduction suppressed growth of a mouse hybridoma cell line and enhanced its antibody production. Cytokine 8:889.
53. Yang-Yen, H.-F., J.-C. Chambard, Y.-L. Sun, T. Smeal, T. J. Schmidt, J. Drouin, and M. Karin. 1990. Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62:1205.
54. Haselmann, J., and M. Goppelt-Struebe. 1997. Glucocorticoids inhibit oncostatin M-induced phospholipase A2 gene expression in human hepatoma cells. Cytokine 9:199.
55. Murakami-Mori, K., S. Mori, T. Taga, T. Kishimoto, and S. Nakamura. 1997. Enhancement of gp130-mediated tyrosine phosphorylation of STAT3 and its DNA-binding activity in dexamethasone-treated AIDS-associated Kaposi's sarcoma cells: selective synergy between dexamethasone and gp130-related growth factors in Kaposi's sarcoma cell proliferation. J. Immunol. 158:5518.
56. Liu, J., M. Shoyab, and R. I. Grove. 1993. Induction of Egr-1 by oncostalin M precedes up-regulation of low density lipoprotein receptors in HepG2 cells. Cell Growth Differ. 4:611.
57. Ziemiecki, A., A. G. Harper, and A. F. Wilks. 1994. JAK protein tyrosine kinases: their role in cytokine signaling. Trends Cell Biol. 4:207.
58. Ihle, J. N. 1996. STATs: signal transducers and activators of transcription. Cell 84:331.
59. Stancato, L. F., M. Sakatsume, M. David, P. Dent, F. Dong, E. F. Petricoin, J. J. Krolewski, O. Silvennoinen, P. Saharinen, J. Pierce, C. J. Marshall, T. Sturgill, D. S. Finbloom, and A. C. Larner. 1997. β interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway. Mol. Cell Biol. 17:3833.
60. Kolodziejczyk, S. M., and B. K. Hall. 1996. Signal transduction and TGF-β superfamily receptors. Biochem. Cell Biol. 74:299.
61. Amaral, M. C., S. Miles, G. Kumar, and A. E. Nel. 1993. Oncostatin-M stimulates tyrosine protein phosphorylation in parallel with the activation of p42 MAPK/ERK-2 in Kaposi's cells: evidence that this pathway is important in Kaposi cell growth. J. Clin. Invest. 92:848.
62. Bugno, M., L. Graeve, P. Gatsios, A. Koj, P. C. Heinrich, J. Travis, and T. Kordula. 1995. Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter. Nucleic Acids Res. 23:5041.
63. Korzus, E., H. Nagase, R. Rydell, and J. Travis. 1996. The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression. J. Biol. Chem. 272:1188.