Nitric oxide metabolism in mammalian cells: Substrate and inhibitor profiles of a NADPH-cytochrome P450 oxidoreductase-coupled microsomal nitric oxide dioxygenase

Free Radical Biology and Medicine

Volumn 37, Issue 2, 2004, Pages 216-228

  Hallstrom, Craig K ^b   Gardner, Anne M ^b   Gardner, Paul R ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b NONE

Author keywords

Allicin; BHT; butylated hydroxytoluene; Carbon monoxide; copper, zinc superoxide dismutase; Cu,ZnSOD; Cyanide; CYPOR; Cytochrome P450; DMSO; Free radicals; Hemoglobin; Imidazole; Microsome; NADPH cytochrome P450 oxidoreductase; Nitric oxide dioxygenase

Indexed keywords

ALLICIN; CARBON MONOXIDE; CLOTRIMAZOLE; CYANIDE; CYTOCHROME C3; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; DIGITONIN; DIPHENYLIODONIUM SALT; ECONAZOLE; GARLIC EXTRACT; HEME OXYGENASE; HEME OXYGENASE INHIBITOR; IMIDAZOLE; IMMUNOGLOBULIN G ANTIBODY; KETOCONAZOLE; METRONIDAZOLE; MICONAZOLE; NITRATE; NITRIC OXIDE; NITRIC OXIDE DIOXYGENASE; OXYGEN; OXYGENASE; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; SODIUM CYANIDE; SUPEROXIDE; TROLEANDOMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CATALYSIS; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MAMMAL CELL; METABOLIC ACTIVATION; METABOLISM; MICROSOME; NITRIC OXIDE METABOLISM; OXYGENATION; PRIORITY JOURNAL; PROTEIN FUNCTION;

CACO-2 CELLS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FREE RADICALS; HEME OXYGENASE (DECYCLIZING); HEMOGLOBINS; HUMANS; IMMUNOGLOBULIN G; KINETICS; MICROSOMES; MICROSOMES, LIVER; MODELS, CHEMICAL; NADPH-FERRIHEMOPROTEIN REDUCTASE; NITRIC OXIDE; OXYGEN; OXYGENASES; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; SUPEROXIDES; TIME FACTORS; ZINC;

ALLIUM SATIVUM; MAMMALIA;

EID: 2942556802     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.04.031     Document Type: Article

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