Garlic and its active metabolite allicin produce endothelium- and nitric oxide-dependent relaxation in rat pulmonary arteries

Clinical and Experimental Pharmacology and Physiology

Volumn 29, Issue 1-2, 2002, Pages 84-91

  Ku, David D ^a   Abdel Razek, Tarek T ^a   Dai, Jun ^a   Kim Park, SangAe ^a   Fallon, Michael B ^b   Abrams, Gary A ^b  

^a The Purdue Univ Univ of Alabama at Birmingham Botanical Center for Age Related Disease   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Allicin; Alliinase; Endothelium; Garlic; Nitric oxide; Pulmonary; Vasorelaxation

Indexed keywords

ACETYLCHOLINE; ALLICIN; ALLIIN LYASE; GARLIC EXTRACT; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE DONOR; PHENYLEPHRINE; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY ENDOTHELIUM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; MALE; MICROFILTRATION; NONHUMAN; PULMONARY ARTERY; RAT; TACHYPHYLAXIS; VASODILATATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; GARLIC; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANT STEMS; PULMONARY ARTERY; RATS; SULFINIC ACIDS; VASODILATION;

EID: 0036151125     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2002.03596.x     Document Type: Article

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