Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: Implications for nuclear toxicity in Huntington's disease pathogenesis

NeuroMolecular Medicine

Volumn 7, Issue 4, 2005, Pages 297-310

  Sayer, Jonathan A ^a   Manczak, Maria ^a   Akileswaran, Lakshmi ^a   Reddy, P Hemachandra ^a   Coghlan, Vincent M ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Huntingtin; Huntington's disease; Nuclear aggregates; Nuclear matrix; Scaffold protein

Indexed keywords

HUNTINGTIN; NUCLEAR MATRIX PROTEIN; POLYGLUTAMINE; PROTEIN; PROTEIN HYPA; PROTEIN NAKAP; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRAIN TISSUE; CELL NUCLEUS MATRIX; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HUNTINGTON CHOREA; IN VITRO STUDY; MALE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MUTAGENESIS; NERVE CELL NECROSIS; NEUROCHEMISTRY; NEUROPATHOLOGY; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM; YEAST;

AGED; ANIMALS; BRAIN; CELL LINE; CELL NUCLEUS; FEMALE; HUMANS; HUNTINGTON DISEASE; MALE; MICE; MIDDLE AGED; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR MATRIX; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PROLINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 29244464786     PISSN: 15351084     EISSN: None     Source Type: Journal    
DOI: 10.1385/NMM:7:4:297     Document Type: Article

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