Ethanol exposure and withdrawal sensitizes the rat hippocampal CA1 pyramidal cell region to β-amyloid (25-35)-induced cytotoxicity: NMDA receptor involvement

Alcoholism: Clinical and Experimental Research

Volumn 29, Issue 11, 2005, Pages 2063-2069

  Self, Rachel L ^a   Smith, Katherine J ^a   Mulholland, Patrick J ^a   Prendergast, Mark A ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alcohol Withdrawal; Alzheimer's Disease; NMDA Receptor; Organotypic Slice Cultures

Indexed keywords

ALCOHOL; AMYLOID BETA PROTEIN[25-35]; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PROPIDIUM IODIDE;

ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DENTATE GYRUS; EXPOSURE; FEMALE; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

ALCOHOL DRINKING; ALCOHOLISM; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; HIPPOCAMPUS; PROPIDIUM; PYRAMIDAL CELLS; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; TISSUE CULTURE TECHNIQUES;

ANIMALIA;

EID: 29044436586     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.alc.0000187591.82039.b2     Document Type: Article

References (51)

1. Abramov AY, Canevari L, Duchen MR (2003) Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity. The Journal of Neuroscience 23 (12):5088-5095.
2. Ball MJ (1978) Topographic distribution of neurofibrillary tangles and granulovascular degeneration in hippocampal cortex of aging and demented patients. A quantitative study. Acta Neuropathol (Berl) 42:73-80.
3. Ball MJ, Hachinski V, Fox A et al (1985) A new definition of Alzheimer's disease: a hippocampal dementia. Lancet 14-16.
4. Behl C, Davis JB, Lesley R, Schubert D (1994) Hydrogen peroxide mediates amyloid β protein toxicity. Cell 77:817-822.
5. Belmadani A, Kumar S, Schipma M, Collins MA, Neafsey EJ (2004) Inhibition of amyloid-β-induced neurotoxicity and apoptosis by moderate ethanol preconditioning. Neuroreport 15:2093-2096.
6. Bobich JA, Zheng Q, Campbell A (2004) Incubation of nerve endings with a physiological concentration of Abetal-42 activates CaV2.2(N-Type)-voltage operated calcium channels and acutely increases glutamate and noradrenaline release. J Alzheimers Dis 6:243-255.
7. Braak H (1985) On areas of transition between entorhinal allocortex and temporal isocortex in the human brain. Normal morphology and lamina-specific pathology in Alzheimer's disease. Acta Neuropathol (Berl) 68:325-332.
8. Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl) 82:239-259.
9. Brennan CH, Lewis A, Littleton JM (1989) Membrane receptors, involved in up-regulation of calcium channels in bovine adrenal chromaffin cells, chronically exposed to ethanol. Neuropharmacology 28:1303-1307.
10. Casley C, Land J, Sharpe M, Clark J, Duchen M, Canevari L (2002) β-amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons. Neurobiol Dis 10:258-267.
11. Davidson M, Wilce P (1998) Chronic ethanol treatment leads to increased ornithine decarboxylase activity: implications for a role of polyamines in ethanol dependence and withdrawal. Alc Clin Exp Res 22:1205-1211.
12. Davies DL, Machu TK, Guo Y, Alkana RL (2002) Ethanol sensitivity in ATP-gated P2X receptors is subunit dependent. Alcohol Clin Exp Res 26:773-778.
13. deLeon MJ, Desanti S, Zinkowski R, Mehta PD, Pratico D, Segal S, Clark C, Kerkman D, Debernardis J, Li J, Lair L, Reisberg B, Tsui W, Rusinek H (2004) MRI and CSF studies in the early diagnosis of Alzheimer's disease. Journal of Internal Medicine 256:205-223.
14. Devaud LL, Matthews DB, Morrow AL (1999) Gender impacts behavioral and neurochemical adaptations in ethanol-dependent rats. Pharmacol Biochem Behav 64:841-849.
15. Devaud LL, Morrow AL (1999) Gender-selective effects of ethanol dependence on NMDA receptor subunit expression in cerebral cortex, hippocampus and hypothalamus. Eur J Pharmacol 369:331-334.
16. Dolin S, Little H, Hudspith M, Pagonis C, Littleton J. (1987) Increased dihydropyridine-sensitive calcium channels in rat brain may underlie ethanol physical dependence. Neuropharmacology. 26:275-279.
17. Floden AM, Li S, Combs CK (2005) β-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor α and NMDA receptors. Neurobiology of Disease 25:2566-2575.
18. Francis PT (2003) Glutamatergic systems in Alzheimer's disease. Int J Geriatr Psychiatry 18:S15-S21.
19. Gibson DA, Harris BR, Prendergast MA, Hart SR, Blanchard JA, II, Holley RC, Pedigo NW, Littleton JM (2003) Polyamines contribute to ethanol withdrawal-induced neurotoxicity in rat hippocampal slice cultures through interactions with the NMDA receptor. Alcohol Clin Exp Res 27:1099-1106.
20. Harding AJ, Wong A, Svoboda M, Kril JJ, Halliday GM (1997) Chronic alcohol consumption does not cause hippocampal neuron loss in humans. Hippocampus 7:78-87.
21. Harris BR, Gibson DA, Prendergast MA, Blanchard JA, Holley RC, Hart SR, Scotland RL, Foster TC, Pedigo NW, Littleton JM (2003) The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors. Alc Clin Exp Res 27:1724-1735.
22. Hommer D, Momenan R, Kaiser E, Rawlings R (2001) Evidence for a gender-related effect of alcoholism on brain volumes. Am J Psychiatry 158:198-204.
23. Hynd MR, Scott HL, Dodd PR (2004) Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. Neurochemistry International 45:583-595.
24. D-aspartate receptor function. Mol Pharmacol 41:1142-1148.
25. Laasko MP (2002) Structural imaging in cognitive impairment and the dementias: an update. Curr Opin Neurol 15:415-421.
26. Letenneur L (2004) Risk of dementia and alcohol and wine consumption: a review of recent results. Biol Res 37:189-93.
27. Li C, Xiong K, Weight FF (2000) Ethanol inhibition of adenosine 5′-triphosphate-activated current in freshly isolated adult rat hippocampal CAl neurons. Neurosci Lett. 8:295:77-80.
28. Li HF, Kendig JJ (2003) Ethanol withdrawal hyper-responsiveness mediated by NMDA receptors in spinal cord motor neurons. Br J Pharmacol 139:73-80.
29. Mann K, Agartz I, Harper C, Shoaf S, Rawlings RR, Momenan R, Hommer DW, Pfefferbaum A, Sullivan EV, Anton RF Drobes DJ, George MS, Bares R, Machulla HJ, Mundle G, Reimold M, Heinz A (2001) Neuroimaging in alcoholism: ethanol and brain damage. Alcohol Clin Exp Res 24:A183.
30. Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE (1992) β-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 12:376-389.
31. Mattson MP, Goodman Y, Luo H, Fu W, Furukawa K (1997) Activation of NF-B protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration. J Neurosci Res 49:681-697.
32. Mayeux R, Sano M (1999) Treatment of Alzheimer's Disease. N Engl J Med 341:1670-79.
33. Miguel-Hidalgo JJ, Alvarez XA, Cacabelos R, Quack G (2002) Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40). Brain Res 958:210-221.
34. Movsesyan VA, Stoica BA, Faden AI (2004) MGLuR5 activation reduces β-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor. J of Neurochemistry 89:1528-1536.
35. Nagy J, Laszlo L (2002) Increased sensitivity to NMDA is involved in alcohol-withdrawal induced cytotoxicity observed in primary cultures of cortical neurones chronically pre-treated with ethanol. Neurochem Int 40:585-91.
36. Prendergast MA, Harris BR, Mulholland PJ, Blanchard II JA, Gibson DA Holley RC, Littleton JM (2004) Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-D-aspartate receptors. Neuroscience 124:869-77.
37. Proctor AW (2000) Abnormalities in non-cholinergic neurotransmitter systems in Alzheimer's Disease. In: O'Brien J, Ames D, Burns A (eds.) Dementia, second ed. Edward Arnold, Oxford, pp. 433-442.
38. Rossetti ZL, Carboni S, Fadda F (1999) Glutamate-induced increase of extracellular glutamate through N-methyl-D-aspartate receptors in ethanol withdrawal. Neuroscience 93:1135-1140.
39. Rowan MJ, Klyubin I, Wang Q, Anwyl R (2004) Mechanisms of the inhibitory effects of amyloid β-protein on synaptic plasticity. Expl Gerontol 39:1661-1667.
40. Rudolph JG, Walker DW, Imuro Y, Thurman RG, Crews F (1997) NMDA receptor binding in adult rat brain after several chronic ethanol treatment protocols. Alcohol Clin Exp Res 21:1508-1519.
41. Ruitenberg A, van Swieten JC, Witteman JCM, Mehta KM, van Duijn CM, Hofman A, Breteler MMB (2002) Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet 359:281-286.
42. Saland LC, Hastings CM, Abeyta A, Chavez JB (2005) Chronic ethanol modulates delta and mu-opioid receptor expression in rat CNS: I mMu-nohistochemical analysis with quantitative confocal microscopy. Neurosci Lett 38:163-168.
43. Self RL, Mulholland PJ, Harris BR, Nath A, Prendergast MA (2004) Cytotoxic effects of exposure to the human immunodeficiency virus type 1 protein Tat in the hippocampus are enhanced by prior ethanol treatment. Alcohol Clin Exp Res 28:1916-1924.
44. Small DH, McLean C (1999) Alzheimer's disease and the amyloid-β protein: what is the role of amyloid? J Neurochem 73:443-449.
45. Stix B, Reiser G (1998) β-amyloid peptide 25-35 regulates basal and hormone-stimulated Ca2+ levels in cultured rat astrocytes. Neurosci Lett 243:121-124.
46. 1-40 is toxic to inward channels of dissociated hippocampal and cortical neurons of rats. Neurobiology of Disease 14:567-578.
47. Trevisan LA, Boutros N, Petrakis IL, Krystal JH (1998) Complications of alcohol withdrawal: pathophysiological insights. Alcohol Health Res World 22:61-66.
48. Trevisan L, Fitzgerald LW, Brose N, Gasic GP, Heinemann SF, Duman RS, Nestler EJ (1994) Chronic ingestion of ethanol upregulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus. J. Neurochem 62:1635-1638.
49. Yamada K, Takayanagi M, Kamei H, Nagai T, Dohniwa M, Kobayashi K, Yoshida S, Ohhara T, Takauma K, Nabeshima T (2005) Effects of memantine and donezepil on amyloid beta-induced memory impairment in a delayed-matching to position task in rats. Behav Brain Res, in press.
50. Ye C, Walsh DM, Selkoe DJ Hartley DM (2004) Amyloid beta-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation. Neurosci Lett 366:320-325.
51. Zimmer J, Kristensen BW, Jakobsen B, Noraberg J (2000) Excitatory amino acid neurotoxicity and modulation of glutamate receptor expression in organotypic brain slice cultures. Amino Acids 19:7-21.