Actinodaphnine induces apoptosis through increased nitric oxide, reactive oxygen species and down-regulation of NF-κB signaling in human hepatoma Mahlavu cells

Food and Chemical Toxicology

Volumn 44, Issue 3, 2006, Pages 344-354

  Hsieh, Tian Jye ^a   Liu, Tsan Zon ^b   Lu, Fung Jou ^c   Hsieh, Pei Ying ^a   Chen, Ching Hsein ^a  

^a FOOYIN UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Actinodaphnine; Apoptosis; Hepatoma; NF B; Nitric oxide; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ACTINODAPHNINE; ANTIOXIDANT; CASPASE 3; CASPASE 7; CASPASE INHIBITOR; DEXAMETHASONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL MEMBRANE POTENTIAL; CINNAMOMUM; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; HEPATOMA CELL; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; SIGNAL TRANSDUCTION;

APOPTOSIS; CASPASES; DIOXOLANES; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUGS, CHINESE HERBAL; ENZYME ACTIVATION; HUMANS; IN SITU NICK-END LABELING; MITOCHONDRIAL MEMBRANES; NF-KAPPA B; NITRIC OXIDE; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED;

CINNAMOMUM; LAURACEAE;

EID: 28844466079     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2005.08.005     Document Type: Article

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