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Volumn 19, Issue 5, 1999, Pages 408-431

Phase-trafficking reagents and phase-switching strategies for parallel synthesis

Author keywords

[No Author keywords available]

Indexed keywords

TETRABUTYLAMMONIUM FLUORIDE; UNCLASSIFIED DRUG;

EID: 0032879345     PISSN: 01986325     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1128(199909)19:5<408::AID-MED7>3.0.CO;2-J     Document Type: Conference Paper
Times cited : (67)

References (69)
  • 1
    • 0000074870 scopus 로고    scopus 로고
    • Strategy and tactics in combinatorial organic synthesis. Applications to drug discovery
    • Gordon EM, Gallop MA, Patel DV. Strategy and tactics in combinatorial organic synthesis. Applications to drug discovery. Acc Chem Res 1996;29:144.
    • (1996) Acc Chem Res , vol.29 , pp. 144
    • Gordon, E.M.1    Gallop, M.A.2    Patel, D.V.3
  • 2
    • 7044263277 scopus 로고    scopus 로고
    • Synthesis and applications of small molecule libraries
    • Thompson LA, Ellman JA. Synthesis and applications of small molecule libraries. Chem Rev 1996;96:555.
    • (1996) Chem Rev , vol.96 , pp. 555
    • Thompson, L.A.1    Ellman, J.A.2
  • 3
    • 0031001699 scopus 로고    scopus 로고
    • Solid-phase organic reactions. II: A review of the literature November 95-November 96
    • Hermkens PHH, Ottenheijm HCJ, Rees D. Solid-phase organic reactions. II: A review of the literature November 95-November 96. Tetrahedron 1997;53:5643.
    • (1997) Tetrahedron , vol.53 , pp. 5643
    • Hermkens, P.H.H.1    Ottenheijm, H.C.J.2    Rees, D.3
  • 4
    • 0025893762 scopus 로고
    • General method for rapid synthesis of multicomponent peptide mixtures
    • Furka A, Sebestyen F, Asgedom M, Dibo G. General method for rapid synthesis of multicomponent peptide mixtures. Int J Pept Protein Res 1991;37:487.
    • (1991) Int J Pept Protein Res , vol.37 , pp. 487
    • Furka, A.1    Sebestyen, F.2    Asgedom, M.3    Dibo, G.4
  • 8
    • 0028815228 scopus 로고
    • Radio frequency tag encoded combinatorial library method for the discovery of tripeptide-substituted cinnamic acid inhibitors of the protein tyrosine phosphatase PTP1B
    • Moran EJ, Sarshar S, Cargill JF, Shahbaz MM, Lio AM, Mjalli AMM, Armstrong RW. Radio frequency tag encoded combinatorial library method for the discovery of tripeptide-substituted cinnamic acid inhibitors of the protein tyrosine phosphatase PTP1B. J Am Chem Soc 1995;117:10787.
    • (1995) J Am Chem Soc , vol.117 , pp. 10787
    • Moran, E.J.1    Sarshar, S.2    Cargill, J.F.3    Shahbaz, M.M.4    Lio, A.M.5    Mjalli, A.M.M.6    Armstrong, R.W.7
  • 11
    • 0031098534 scopus 로고    scopus 로고
    • Organic synthesis on soluble polymer supports: Liquid-phase methodologies
    • Gravert DJ, Janda KD. Organic synthesis on soluble polymer supports: Liquid-phase methodologies. Chem Rev 1997;97:489.
    • (1997) Chem Rev , vol.97 , pp. 489
    • Gravert, D.J.1    Janda, K.D.2
  • 12
    • 0031550836 scopus 로고    scopus 로고
    • A soluble polymer-bound approach to the sharpless catalytic Asymmetric Dihydroxylation (AD) reaction: Preparation and application of a [(DHQD)2PHAL-PEG-OMe ligand
    • Han H, Janda KD. A soluble polymer-bound approach to the Sharpless catalytic asymmetric dihydroxylation (AD) reaction: preparation and application of a [(DHQD)2PHAL-PEG-OMe) ligand. Tetrahedron Lett 1997;38:1527.
    • (1997) Tetrahedron Lett , vol.38 , pp. 1527
    • Han, H.1    Janda, K.D.2
  • 13
    • 0030883333 scopus 로고    scopus 로고
    • Synthesis of prostaglandin E2 methyl ester on a soluble-polymer support for the construction of prostanoid libraries
    • Chen S, Janda KD. Synthesis of prostaglandin E2 methyl ester on a soluble-polymer support for the construction of prostanoid libraries. J Am Chem Soc 1997;119;8724.
    • (1997) J Am Chem Soc , vol.119 , pp. 8724
    • Chen, S.1    Janda, K.D.2
  • 15
    • 33749491911 scopus 로고
    • Smart ligands that regulate homogeneously catalyzed reactions
    • Bergbreiter DE, Zhang L, Mariagnanam VM. Smart ligands that regulate homogeneously catalyzed reactions. J Am Chem Soc 1993;115:9295.
    • (1993) J Am Chem Soc , vol.115 , pp. 9295
    • Bergbreiter, D.E.1    Zhang, L.2    Mariagnanam, V.M.3
  • 16
    • 0030827397 scopus 로고    scopus 로고
    • Water-soluble polymer-bound, recoverable palladium(0)-phosphine catalysts
    • Bergbreiter DE, Liu Y-S. Water-soluble polymer-bound, recoverable palladium(0)-phosphine catalysts. Tetrahedron Lett 1997;38:7843.
    • (1997) Tetrahedron Lett , vol.38 , pp. 7843
    • Bergbreiter, D.E.1    Liu, Y.-S.2
  • 17
    • 0000077126 scopus 로고    scopus 로고
    • Thermomorphic rhodium(I) and palladium(0) catalysts
    • Bergbreiter DE, Liu Y-S, Osburn PL. Thermomorphic rhodium(I) and palladium(0) catalysts. J Am Chem Soc 1998;120:4250.
    • (1998) J Am Chem Soc , vol.120 , pp. 4250
    • Bergbreiter, D.E.1    Liu, Y.-S.2    Osburn, P.L.3
  • 18
    • 0029914650 scopus 로고    scopus 로고
    • Tris(2-(perfluorohexyl)ethyl)tin hydride: A new fluorous reagent for use in traditional organic synthesis and liquid phase combinatorial synthesis
    • Curran DP, Hadida S. Tris(2-(perfluorohexyl)ethyl)tin hydride: A new fluorous reagent for use in traditional organic synthesis and liquid phase combinatorial synthesis. J Am Chem Soc 1996;118:2531.
    • (1996) J Am Chem Soc , vol.118 , pp. 2531
    • Curran, D.P.1    Hadida, S.2
  • 19
    • 0031029886 scopus 로고    scopus 로고
    • Fluorous synthesis: A fluorous-phase strategy for improving separation efficiency in organic synthesis
    • Studer A, Hadida S, Ferritto R, Kim S-Y, Jeger P, Wipf P, Curran DP. Fluorous synthesis: a fluorous-phase strategy for improving separation efficiency in organic synthesis. Science 1997;275:823.
    • (1997) Science , vol.275 , pp. 823
    • Studer, A.1    Hadida, S.2    Ferritto, R.3    Kim, S.-Y.4    Jeger, P.5    Wipf, P.6    Curran, D.P.7
  • 20
    • 0032884398 scopus 로고    scopus 로고
    • Parallel synthesis with fluorous reagents and reactants
    • Curran DP. Parallel synthesis with fluorous reagents and reactants. Med Res Rev 1999;19:432-438.
    • (1999) Med Res Rev , vol.19 , pp. 432-438
    • Curran, D.P.1
  • 21
    • 0029926720 scopus 로고    scopus 로고
    • Novel solution phase strategy for the synthesis of chemical libraries containing small organic molecules
    • Cheng S, Comer DD, Williams JP, Myers PL, Boger DL. Novel solution phase strategy for the synthesis of chemical libraries containing small organic molecules. J Am Chem Soc 1996;118:2567.
    • (1996) J Am Chem Soc , vol.118 , pp. 2567
    • Cheng, S.1    Comer, D.D.2    Williams, J.P.3    Myers, P.L.4    Boger, D.L.5
  • 22
    • 0029950789 scopus 로고    scopus 로고
    • A solution-phase strategy for the synthesis of chemical libraries containing small organic molecules: A universal and dipeptide mimetic template
    • Cheng S, Tarby CM, Comer DD, Williams JP, Caporale LH, Myers PL, Boger DL. A solution-phase strategy for the synthesis of chemical libraries containing small organic molecules: a universal and dipeptide mimetic template. Bioorg Med Chem 1996;4:727.
    • (1996) Bioorg Med Chem , vol.4 , pp. 727
    • Cheng, S.1    Tarby, C.M.2    Comer, D.D.3    Williams, J.P.4    Caporale, L.H.5    Myers, P.L.6    Boger, D.L.7
  • 23
    • 3543025082 scopus 로고    scopus 로고
    • Multistep convergent solution-phase combinatorial synthesis and deletion synthesis deconvolution
    • Boger DL, Chai W, Jin Q. Multistep convergent solution-phase combinatorial synthesis and deletion synthesis deconvolution. J Am Chem Soc 1998;120:7220.
    • (1998) J Am Chem Soc , vol.120 , pp. 7220
    • Boger, D.L.1    Chai, W.2    Jin, Q.3
  • 24
    • 0030607141 scopus 로고    scopus 로고
    • Use of solid supported nucleophiles and electrophiles for the purification of non-peptide small molecule libraries
    • Kaldor SW, Siegel MG, Fritz JE, Dressman BA, Hahn PJ. Use of solid supported nucleophiles and electrophiles for the purification of non-peptide small molecule libraries. Tetrahedron Lett 1996;37:7193.
    • (1996) Tetrahedron Lett , vol.37 , pp. 7193
    • Kaldor, S.W.1    Siegel, M.G.2    Fritz, J.E.3    Dressman, B.A.4    Hahn, P.J.5
  • 25
    • 0030952762 scopus 로고    scopus 로고
    • Chemical library purification strategies based on principles of complementary molecular reactivity and molecular recognition
    • Flynn DL, Crich JZ, Devraj RV, Hockerman SL, Parlow JJ, South MS, Woodard S. Chemical library purification strategies based on principles of complementary molecular reactivity and molecular recognition. J Am Chem Soc 1997;119:4874.
    • (1997) J Am Chem Soc , vol.119 , pp. 4874
    • Flynn, D.L.1    Crich, J.Z.2    Devraj, R.V.3    Hockerman, S.L.4    Parlow, J.J.5    South, M.S.6    Woodard, S.7
  • 26
    • 0030987922 scopus 로고    scopus 로고
    • Polymer-supported quenching reagents for parallel purification
    • Booth R J, Hodges JC. Polymer-supported quenching reagents for parallel purification. J Am Chem Soc 1997;119:4882.
    • (1997) J Am Chem Soc , vol.119 , pp. 4882
    • Booth, R.J.1    Hodges, J.C.2
  • 27
    • 0031152048 scopus 로고    scopus 로고
    • Combinatorial chemistry using polymer-supported reagents
    • Kaldor SW, Siegel M. Combinatorial chemistry using polymer-supported reagents. Curr Opin Chem Biol 1997;1:101.
    • (1997) Curr Opin Chem Biol , vol.1 , pp. 101
    • Kaldor, S.W.1    Siegel, M.2
  • 28
    • 0002369226 scopus 로고    scopus 로고
    • Recent advances in polymer-assisted solution-phase chemical library synthesis and purification
    • Flynn DL, Devraj RV, Parlow JJ. Recent advances in polymer-assisted solution-phase chemical library synthesis and purification. Curr Opin Drug Disc Dev 1998;1:41.
    • (1998) Curr Opin Drug Disc Dev , vol.1 , pp. 41
    • Flynn, D.L.1    Devraj, R.V.2    Parlow, J.J.3
  • 29
    • 0030598016 scopus 로고    scopus 로고
    • The use of anion exchange resins for the synthesis of combinatorial libraries containing aryl and heteroaryl ethers
    • Parlow JJ. The use of anion exchange resins for the synthesis of combinatorial libraries containing aryl and heteroaryl ethers. Tetrahedron Lett 1996;37:5257.
    • (1996) Tetrahedron Lett , vol.37 , pp. 5257
    • Parlow, J.J.1
  • 30
    • 0030767571 scopus 로고    scopus 로고
    • Polymer-supported bases in combinatorial chemistry: Synthesis of aryl ethers from phenols and alkyl halides and aryl halides
    • Xu W, Mohan R, Morrissey MM. Polymer-supported bases in combinatorial chemistry: synthesis of aryl ethers from phenols and alkyl halides and aryl halides. Tetrahedron Lett 1997;38:7337.
    • (1997) Tetrahedron Lett , vol.38 , pp. 7337
    • Xu, W.1    Mohan, R.2    Morrissey, M.M.3
  • 31
    • 0032487973 scopus 로고    scopus 로고
    • A new scavenger resin for amines
    • Coppola GM. A new scavenger resin for amines. Tetrahedron Lett 1998;39:8233.
    • (1998) Tetrahedron Lett , vol.39 , pp. 8233
    • Coppola, G.M.1
  • 32
    • 0032497346 scopus 로고    scopus 로고
    • A mixed resin bed for the quenching and purification of tetrabutylammonium fluoride mediated desilylating reactions
    • Parlow JJ, Vazquez ML, Flynn, DL. A mixed resin bed for the quenching and purification of tetrabutylammonium fluoride mediated desilylating reactions. Bioorg Med Chem Lett 1998;8:2391X.
    • (1998) Bioorg Med Chem Lett , vol.8
    • Parlow, J.J.1    Vazquez, M.L.2    Flynn, D.L.3
  • 33
    • 0032403246 scopus 로고    scopus 로고
    • Generation of a library of 4-thiazolidinones utilizing Polymer Supported Quench (PSQ) reagent methodology
    • Ault-Justus SE, Hodges JC, Wilson MW. Generation of a library of 4-thiazolidinones utilizing polymer supported quench (PSQ) reagent methodology. Biotechnol Bioeng 1998;61:17.
    • (1998) Biotechnol Bioeng , vol.61 , pp. 17
    • Ault-Justus, S.E.1    Hodges, J.C.2    Wilson, M.W.3
  • 34
    • 0032537038 scopus 로고    scopus 로고
    • Solution-phase parallel synthesis of a benzoxazinone library using Complementary Molecular Reactivity and Molecular Recognition (CMR/R) purification technology
    • Parlow JJ, Flynn DL. Solution-phase parallel synthesis of a benzoxazinone library using complementary molecular reactivity and molecular recognition (CMR/R) purification technology. Tetrahedron 1998; 54:4013.
    • (1998) Tetrahedron , vol.54 , pp. 4013
    • Parlow, J.J.1    Flynn, D.L.2
  • 35
    • 0000965816 scopus 로고    scopus 로고
    • Combinatorial synthesis of 2-thioxo-4-dihydropyrimidinones
    • Sim MM, Lee CL, Ganesan A. Combinatorial synthesis of 2-thioxo-4-dihydropyrimidinones. J Org Chem 1997;62:9358.
    • (1997) J Org Chem , vol.62 , pp. 9358
    • Sim, M.M.1    Lee, C.L.2    Ganesan, A.3
  • 36
    • 0032537040 scopus 로고    scopus 로고
    • Combinatorial synthesis of dihydropyridone libraries and their derivatives
    • Creswell W, Bolton GL, Hodges JC, Meppen M. Combinatorial synthesis of dihydropyridone libraries and their derivatives. Tetrahedron 1998;54:3983.
    • (1998) Tetrahedron , vol.54 , pp. 3983
    • Creswell, W.1    Bolton, G.L.2    Hodges, J.C.3    Meppen, M.4
  • 37
    • 0032497352 scopus 로고    scopus 로고
    • Chemically-tagged Mitsunobu reagents for use in solution-phase chemical library synthesis
    • Starkey GW, Parlow JJ, Flynn DL. Chemically-tagged Mitsunobu reagents for use in solution-phase chemical library synthesis. Bioorg Med Chem Lett 1998;8:2385.
    • (1998) Bioorg Med Chem Lett , vol.8 , pp. 2385
    • Starkey, G.W.1    Parlow, J.J.2    Flynn, D.L.3
  • 38
    • 0000745360 scopus 로고    scopus 로고
    • Versatile acylation of N-nucleophiles using a new polymer-supported 1-hydroxybenzotriazole derivative
    • Pop IE, Deprez BP, Tartar AL. Versatile acylation of N-nucleophiles using a new polymer-supported 1-hydroxybenzotriazole derivative. J Org Chem 1997;62:2594.
    • (1997) J Org Chem , vol.62 , pp. 2594
    • Pop, I.E.1    Deprez, B.P.2    Tartar, A.L.3
  • 39
    • 33845470543 scopus 로고
    • Active ester of polymer-bound 4-hydroxy-3-nitrobenzophenone as useful acylating reagents. Application to peptide synthesis
    • Cohen BJ, Karoly-Hafeli H, Patchornik A. Active ester of polymer-bound 4-hydroxy-3-nitrobenzophenone as useful acylating reagents. Application to peptide synthesis. J Org Chem 1984;49:922.
    • (1984) J Org Chem , vol.49 , pp. 922
    • Cohen, B.J.1    Karoly-Hafeli, H.2    Patchornik, A.3
  • 40
    • 0030202284 scopus 로고    scopus 로고
    • Discovery of a herbicidal lead using polymer-bound activated esters in generating a combinatorial library of amides and esters
    • Parlow JJ, Normansell JE. Discovery of a herbicidal lead using polymer-bound activated esters in generating a combinatorial library of amides and esters. Molecular Diversity 1996;1:217.
    • (1996) Molecular Diversity , vol.1 , pp. 217
    • Parlow, J.J.1    Normansell, J.E.2
  • 41
    • 0011240534 scopus 로고    scopus 로고
    • Polymeric acyl transfer reagents: Synthesis of amides using polystyrene supported oximino esters
    • Kumari KA, Sreekumar K. Polymeric acyl transfer reagents: synthesis of amides using polystyrene supported oximino esters. Polymer 1996;37:171.
    • (1996) Polymer , vol.37 , pp. 171
    • Kumari, K.A.1    Sreekumar, K.2
  • 42
    • 0031375951 scopus 로고    scopus 로고
    • Polystyrene-based hydroxamic esters: Preparation and application as acyl transfer reagents
    • Sophiamma PN, Sreekumar K. Polystyrene-based hydroxamic esters: preparation and application as acyl transfer reagents. Reactive & Functional Polymers 1997;35:169.
    • (1997) Reactive & Functional Polymers , vol.35 , pp. 169
    • Sophiamma, P.N.1    Sreekumar, K.2
  • 43
    • 0032575179 scopus 로고    scopus 로고
    • Solid phase synthesis of urea libraries using a diversifiable thiophenoxy carbonyl linker
    • Dressman BA, Singh U, Kaldor SW. Solid phase synthesis of urea libraries using a diversifiable thiophenoxy carbonyl linker. Tetrahedron Lett. 1998;39:3631.
    • (1998) Tetrahedron Lett. , vol.39 , pp. 3631
    • Dressman, B.A.1    Singh, U.2    Kaldor, S.W.3
  • 45
    • 0030973401 scopus 로고    scopus 로고
    • Automated synthesis and purification of amides: Exploitation of automated solid phase extraction in organic synthesis
    • Lawrence RM, Biller SA, Fryszman OM, Poss MA. Automated synthesis and purification of amides: Exploitation of automated solid phase extraction in organic synthesis. Synthesis 1997;5:553.
    • (1997) Synthesis , vol.5 , pp. 553
    • Lawrence, R.M.1    Biller, S.A.2    Fryszman, O.M.3    Poss, M.A.4
  • 46
    • 0033534495 scopus 로고    scopus 로고
    • Polymer-assisted solution phase synthesis: A general method for sequestration of byproducts formed from activated acyl-transfer reactants
    • Weidner JJ, Parlow JJ, Flynn DL. Polymer-assisted solution phase synthesis: a general method for sequestration of byproducts formed from activated acyl-transfer reactants. Tetrahedron Lett 1999;40:239.
    • (1999) Tetrahedron Lett , vol.40 , pp. 239
    • Weidner, J.J.1    Parlow, J.J.2    Flynn, D.L.3
  • 48
    • 0001534308 scopus 로고    scopus 로고
    • Novel solution-and solid-phase strategies for the parallel and combinatorial synthesis of low-molecular-weight compound libraries
    • Chucholowski A, Masquelin T, Obrecht D, Stadlwieser J, Villalgordo JM. Novel solution-and solid-phase strategies for the parallel and combinatorial synthesis of low-molecular-weight compound libraries. Chimia 1996;50:525.
    • (1996) Chimia , vol.50 , pp. 525
    • Chucholowski, A.1    Masquelin, T.2    Obrecht, D.3    Stadlwieser, J.4    Villalgordo, J.M.5
  • 50
    • 1842713260 scopus 로고    scopus 로고
    • Poly(Ethylene Glycol) (PEG) as a reagent support: The preparation and utility of a PEG-triarylphosphine conjugate in Liquid-Phase Organic Synthesis (LPOS)
    • Wentworth P Jr, Vandersteen AM, Janda KD. Poly(ethylene glycol) (PEG) as a reagent support: the preparation and utility of a PEG-triarylphosphine conjugate in liquid-phase organic synthesis (LPOS). Chem Commun 1997;759.
    • (1997) Chem Commun , pp. 759
    • Wentworth P., Jr.1    Vandersteen, A.M.2    Janda, K.D.3
  • 51
    • 0000035623 scopus 로고    scopus 로고
    • Thermal allylations of aldehydes with a fluorous allylstannane. Separation of organic and fluorous products by solids phase extraction with fluorous reverse phase silica gel
    • Curran DP, Hadida S, He M. Thermal allylations of aldehydes with a fluorous allylstannane. Separation of organic and fluorous products by solids phase extraction with fluorous reverse phase silica gel. J Org Chem 1997;62:6714.
    • (1997) J Org Chem , vol.62 , pp. 6714
    • Curran, D.P.1    Hadida, S.2    He, M.3
  • 52
    • 0032497351 scopus 로고    scopus 로고
    • "Propylene spaced" allyl tin reagents: A new class of fluorous tin reagents for allylations under radical and metal-catalyzed conditions
    • Curran DP, Luo Z, Degenkolb P. "Propylene spaced" allyl tin reagents: A new class of fluorous tin reagents for allylations under radical and metal-catalyzed conditions. Bioorg Med Chem Lett 1998;8:2403.
    • (1998) Bioorg Med Chem Lett , vol.8 , pp. 2403
    • Curran, D.P.1    Luo, Z.2    Degenkolb, P.3
  • 53
    • 0030813190 scopus 로고    scopus 로고
    • In situ chemical tagging: Tetrafluorophthalic anhydride as a "Sequestration Enabling Reagent" (SER) in the purification of solution-phase combinatorial libraries
    • Parlow JJ, Naing W, South MS, Flynn DL. In situ chemical tagging: tetrafluorophthalic anhydride as a "Sequestration Enabling Reagent" (SER) in the purification of solution-phase combinatorial libraries. Tetrahedron Lett 1997;38:7959.
    • (1997) Tetrahedron Lett , vol.38 , pp. 7959
    • Parlow, J.J.1    Naing, W.2    South, M.S.3    Flynn, D.L.4
  • 55
    • 0030964314 scopus 로고    scopus 로고
    • Solution-phase synthesis of a combinatorial thiohydantoin library
    • Sim MM, Ganesan A. Solution-phase synthesis of a combinatorial thiohydantoin library J Org Chem 1997;62:3230.
    • (1997) J Org Chem , vol.62 , pp. 3230
    • Sim, M.M.1    Ganesan, A.2
  • 57
    • 0032494719 scopus 로고    scopus 로고
    • Impurity annihilation; A strategy for solution phase combinatorial chemistry with minimal purification
    • Barren AGM, Smith ML, Zecri FJ. Impurity annihilation; A strategy for solution phase combinatorial chemistry with minimal purification. Chem Commun 1998;2317.
    • (1998) Chem Commun , pp. 2317
    • Barren, A.G.M.1    Smith, M.L.2    Zecri, F.J.3
  • 59
    • 0001768317 scopus 로고    scopus 로고
    • Utility of Complementary Molecular Reactivity and Molecular Recognition (CMR/R) technology and polymer-supported reagents in the solution-phase synthesis of heterocyclic carboxamides
    • Parlow JJ, Mischke DA, Woodard SS. Utility of complementary molecular reactivity and molecular recognition (CMR/R) technology and polymer-supported reagents in the solution-phase synthesis of heterocyclic carboxamides. J Org Chem 1997;62:5908.
    • (1997) J Org Chem , vol.62 , pp. 5908
    • Parlow, J.J.1    Mischke, D.A.2    Woodard, S.S.3
  • 60
    • 0029963887 scopus 로고    scopus 로고
    • Postcondensation modifications of Ugi fourcomponent condensation products: 1-Isocyanocyclohexene as a convertible isocyanide. Mechanism of conversion, synthesis of diverse structures, and demonstration of resin capture
    • Keating TA, Armstrong RW. Postcondensation modifications of Ugi fourcomponent condensation products: 1-Isocyanocyclohexene as a convertible isocyanide. Mechanism of conversion, synthesis of diverse structures, and demonstration of resin capture. J Am Chem Soc 1996;118:2574.
    • (1996) J Am Chem Soc , vol.118 , pp. 2574
    • Keating, T.A.1    Armstrong, R.W.2
  • 61
    • 0030831922 scopus 로고    scopus 로고
    • Parallel synthesis of tamoxifen and derivatives on solid support via resin capture
    • Brown SD, Armstrong RW. Parallel synthesis of tamoxifen and derivatives on solid support via resin capture. J Org Chem 1997;62:7076.
    • (1997) J Org Chem , vol.62 , pp. 7076
    • Brown, S.D.1    Armstrong, R.W.2
  • 62
    • 0030839735 scopus 로고    scopus 로고
    • The application of high-throughput synthesis and purification to the preparation of ethanolamines
    • Shuker AJ, Siegel MG, Matthews DP, Weigel LO. The application of high-throughput synthesis and purification to the preparation of ethanolamines. Tetrahedron Lett 1997;38: 6149.
    • (1997) Tetrahedron Lett , vol.38 , pp. 6149
    • Shuker, A.J.1    Siegel, M.G.2    Matthews, D.P.3    Weigel, L.O.4
  • 63
    • 0032575201 scopus 로고    scopus 로고
    • Parallel synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines by a new three-component condensation
    • Blackburn C, Guan B, Fleming P, Shiosaki K, Tsai S. Parallel synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines by a new three-component condensation. Tetrahedron Lett 1998;39:3635.
    • (1998) Tetrahedron Lett , vol.39 , pp. 3635
    • Blackburn, C.1    Guan, B.2    Fleming, P.3    Shiosaki, K.4    Tsai, S.5
  • 64
    • 0031452355 scopus 로고    scopus 로고
    • Ion-exchange resins for combinatorial synthesis: 2,4 Pyrrolidinediones by Dieckmann condensation
    • Kulkarni BA, Ganesan A. Ion-exchange resins for combinatorial synthesis: 2,4 pyrrolidinediones by Dieckmann condensation. Angew Chem Int Ed Engl 1997;36:2454.
    • (1997) Angew Chem Int Ed Engl , vol.36 , pp. 2454
    • Kulkarni, B.A.1    Ganesan, A.2
  • 65
    • 0031000561 scopus 로고    scopus 로고
    • A strategic alternative to solid phase synthesis: Preparation of a small isoxazoline library by "fluorous synthesis."
    • Studer A, Curran DP. A strategic alternative to solid phase synthesis: Preparation of a small isoxazoline library by "fluorous synthesis." Tetrahedron 1997;53:6681.
    • (1997) Tetrahedron , vol.53 , pp. 6681
    • Studer, A.1    Curran, D.P.2
  • 66
    • 0030599243 scopus 로고    scopus 로고
    • Expedient solid-phase synthesis of putative B-turn mimetics incorporating the i + 1, i + 2, and i + 3 sidechains
    • Virgilio AA, Schurer SC, Ellman JA. Expedient solid-phase synthesis of putative B-turn mimetics incorporating the i + 1, i + 2, and i + 3 sidechains. Tetrahedron Lett 1996;37:6961.
    • (1996) Tetrahedron Lett , vol.37 , pp. 6961
    • Virgilio, A.A.1    Schurer, S.C.2    Ellman, J.A.3
  • 67
    • 0030873736 scopus 로고    scopus 로고
    • Non-acidic cleavage of Wang-derived ethers from solid support: Utilization of a mixed-bed scavenger for DDQ
    • Deegan TL, Gooding OW, Baudart S, Porco JA Jr. Non-acidic cleavage of Wang-derived ethers from solid support: utilization of a mixed-bed scavenger for DDQ. Tetrahedron Lett 1997;38:4973.
    • (1997) Tetrahedron Lett , vol.38 , pp. 4973
    • Deegan, T.L.1    Gooding, O.W.2    Baudart, S.3    Porco J.A., Jr.4
  • 68
    • 0032567966 scopus 로고    scopus 로고
    • Arylsulfonate esters in solid phase organic synthesis. I. Cleavage with amines, thiolate, and imidazole
    • Rueter JK, Nortey SO, Baxter EW, Leo GC, Reitz AB. Arylsulfonate esters in solid phase organic synthesis. I. cleavage with amines, thiolate, and imidazole. Tetrahedron Lett 1998;39:975.
    • (1998) Tetrahedron Lett , vol.39 , pp. 975
    • Rueter, J.K.1    Nortey, S.O.2    Baxter, E.W.3    Leo, G.C.4    Reitz, A.B.5
  • 69
    • 0031032613 scopus 로고    scopus 로고
    • Traceless linker: Oxidative activation and displacement of a sulfur-based linker
    • Gayo LM, Suto MJ. Traceless linker: oxidative activation and displacement of a sulfur-based linker. Tetrahedron Lett 1997;38:211.
    • (1997) Tetrahedron Lett , vol.38 , pp. 211
    • Gayo, L.M.1    Suto, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.