N-phenyl-N-purin-6-yl ureas: The design and synthesis of p38α MAP kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 6, 2003, Pages 1191-1194

  Wan, Zehong ^a   Boehm, Jeffrey C ^a   Bower, Michael J ^a   Kassis, Shouki ^a   Lee, John C ^a   Zhao, Baoguang ^a   Adams, Jerry L ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N PHENYL N PURIN 6 YLUREA DERIVATIVE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ARTICLE; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SUBUNIT; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0037463762     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00048-9     Document Type: Article

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