Quantitative structure-activity relationships for small non-peptide antagonists of CXCR2: Indirect 3D approach using the frontal polygon method

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 2, 2006, Pages 352-365

  Khlebnikov, Andrei I ^a   Schepetkin, Igor A ^b   Quinn, Mark T ^b  

^a ALTAI STATE TECHNICAL UNIVERSITY   (Russian Federation)

^b MONTANA STATE UNIVERSITY   (United States)

Author keywords

CXCR2 antagonists; Drug design; Frontal polygons; Molecular descriptors; Molecular modeling; QSAR

Indexed keywords

CARBANILIDE; CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CXCR2; NICOTINAMIDE; OXIDE; QUINOXALINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; CALCULATION; CHEMICAL STRUCTURE; CORRELATION ANALYSIS; DRUG TARGETING; GEOMETRY; GRANULOCYTE; HYDROPHOBICITY; INFLAMMATION; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

GRANULOCYTES; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RECEPTORS, INTERLEUKIN-8B;

EID: 28844440880     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.08.026     Document Type: Article

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