-
2
-
-
12444305616
-
-
AIHW Cat. No. CVD 27. Canberra (ACT): Australian Institute of Health and Welfare and the National Heart Foundation of Australia
-
Australian Institute of Health and Welfare (AIHW) and Heart Foundation. Heart, stroke and vascular diseases: Australian facts 2004. AIHW Cat. No. CVD 27. Canberra (ACT): Australian Institute of Health and Welfare and the National Heart Foundation of Australia, 2004: 18-26
-
(2004)
Heart, Stroke and Vascular Diseases: Australian Facts 2004
, pp. 18-26
-
-
-
3
-
-
9144246190
-
Drug development and use in the elderly: Search for the right dose and dosing regimen (Parts I and II)
-
Shah RR. Drug development and use in the elderly: search for the right dose and dosing regimen (Parts I and II). Br J Clin Pharmacol 2004; 58: 452-69
-
(2004)
Br J Clin Pharmacol
, vol.58
, pp. 452-469
-
-
Shah, R.R.1
-
4
-
-
0042820151
-
The clinical pharmacology of ageing
-
Swift CG. The clinical pharmacology of ageing. Br J Clin Pharmacol 2003; 56: 249-53
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 249-253
-
-
Swift, C.G.1
-
6
-
-
0033678668
-
Cardiovascular drug therapy in patients with hepatic diseases and patients with congestive heart failure
-
Sokol SI, Cheng A, Frishman WH, et al. Cardiovascular drug therapy in patients with hepatic diseases and patients with congestive heart failure. J Clin Pharmacol 2000; 40: 11-30
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 11-30
-
-
Sokol, S.I.1
Cheng, A.2
Frishman, W.H.3
-
7
-
-
0030911821
-
Drug administration in patients with renal insufficiency: Minimising renal and extrarenal toxicity
-
Matzke GR, Frye RF. Drug administration in patients with renal insufficiency: minimising renal and extrarenal toxicity. Drug Saf 1997; 16: 205-31
-
(1997)
Drug Saf
, vol.16
, pp. 205-231
-
-
Matzke, G.R.1
Frye, R.F.2
-
8
-
-
0029022307
-
Pharmacokinetic changes in patients with oedema
-
Vrhovac B, Sarapa N, Bakran I, et al. Pharmacokinetic changes in patients with oedema. Clin Pharmacokinet 1995; 28: 405-18
-
(1995)
Clin Pharmacokinet
, vol.28
, pp. 405-418
-
-
Vrhovac, B.1
Sarapa, N.2
Bakran, I.3
-
9
-
-
0032713507
-
Effects of liver disease on pharmacokinetics: An update
-
Rodighiero V. Effects of liver disease on pharmacokinetics: an update. Clin Pharmacokinet 1999; 37: 399-431
-
(1999)
Clin Pharmacokinet
, vol.37
, pp. 399-431
-
-
Rodighiero, V.1
-
10
-
-
0037389914
-
Drug metabolism in chronic renal failure
-
Pichette V, Leblond FA. Drug metabolism in chronic renal failure. Curr Drug Metab 2003; 4: 91-103
-
(2003)
Curr Drug Metab
, vol.4
, pp. 91-103
-
-
Pichette, V.1
Leblond, F.A.2
-
11
-
-
0035136520
-
Pharmacology and pharmacotherapy of cardiovascular drugs in patients with chronic renal disease
-
Barbour MM, McKindley DS. Pharmacology and pharmacotherapy of cardiovascular drugs in patients with chronic renal disease. Semin Nephrol 2001; 21: 66-78
-
(2001)
Semin Nephrol
, vol.21
, pp. 66-78
-
-
Barbour, M.M.1
McKindley, D.S.2
-
12
-
-
0030814596
-
Drug administration in chronic liver disease
-
Westphal JF, Brogard JM. Drug administration in chronic liver disease. Drug Saf 1997; 17: 47-73
-
(1997)
Drug Saf
, vol.17
, pp. 47-73
-
-
Westphal, J.F.1
Brogard, J.M.2
-
13
-
-
0027243672
-
Drug dosage in patients during continuous renal replacement therapy: Pharmacokinetic and therapeutic considerations
-
Reetze-Bonorden P, Bohler J, Keller E. Drug dosage in patients during continuous renal replacement therapy: pharmacokinetic and therapeutic considerations. Clin Pharmacokinet 1993; 24: 362-79
-
(1993)
Clin Pharmacokinet
, vol.24
, pp. 362-379
-
-
Reetze-Bonorden, P.1
Bohler, J.2
Keller, E.3
-
14
-
-
0037422592
-
Arterial and cardiac aging: Major share-holders in cardiovascular disease enterprises: Part I. Aging arteries: A 'set up' for vascular disease
-
Lakatta EG, Levy D. Arterial and cardiac aging: major share-holders in cardiovascular disease enterprises: Part I. Aging arteries: a 'set up' for vascular disease. Circulation 2003; 107: 139-46
-
(2003)
Circulation
, vol.107
, pp. 139-146
-
-
Lakatta, E.G.1
Levy, D.2
-
15
-
-
0037458070
-
Arterial and cardiac aging: Major share-holders in cardiovascular disease enterprises: Part II. The aging heart in health: Links to heart disease
-
Lakatta EG, Levy D. Arterial and cardiac aging: major share-holders in cardiovascular disease enterprises: Part II. The aging heart in health: links to heart disease. Circulation 2003; 107: 346-54
-
(2003)
Circulation
, vol.107
, pp. 346-354
-
-
Lakatta, E.G.1
Levy, D.2
-
16
-
-
0037469206
-
Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part III. Cellular and mo-lecular clues to heart and arterial aging
-
Lakatta EG. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III. Cellular and mo-lecular clues to heart and arterial aging. Circulation 2003; 107: 490-7
-
(2003)
Circulation
, vol.107
, pp. 490-497
-
-
Lakatta, E.G.1
-
18
-
-
0034839324
-
Age-associated changes in cardiac matrix and integrins
-
Burgess ML, McCrea JC, Hedrick HL. Age-associated changes in cardiac matrix and integrins. Mech Ageing Dev 2001; 122: 1739-56
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 1739-1756
-
-
Burgess, M.L.1
McCrea, J.C.2
Hedrick, H.L.3
-
20
-
-
0030722166
-
Impaired nitric oxide-mediated vasodilatation and total body nitric oxide production in healthy old age
-
Lond
-
Lyons D, Roy S, Patel M, et al. Impaired nitric oxide-mediated vasodilatation and total body nitric oxide production in healthy old age. Clin Sci (Lond) 1997; 93: 519-25
-
(1997)
Clin Sci
, vol.93
, pp. 519-525
-
-
Lyons, D.1
Roy, S.2
Patel, M.3
-
21
-
-
0034039157
-
Influence of ageing on vasomotor responses of human epicardial coronary arteries
-
Saetrum OO, Ytterberg HT, Saxena PR, et al. Influence of ageing on vasomotor responses of human epicardial coronary arteries. Pharmacol Toxicol 2000; 86: 183-91
-
(2000)
Pharmacol Toxicol
, vol.86
, pp. 183-191
-
-
Saetrum, O.O.1
Ytterberg, H.T.2
Saxena, P.R.3
-
22
-
-
0033983024
-
Aging is associated with endothelial dysfunction in the human forearm vasculature
-
Andrawis N, Jones DS, Abernethy DR. Aging is associated with endothelial dysfunction in the human forearm vasculature. J Am Geriatr Soc 2000; 48: 193-8
-
(2000)
J Am Geriatr Soc
, vol.48
, pp. 193-198
-
-
Andrawis, N.1
Jones, D.S.2
Abernethy, D.R.3
-
23
-
-
0028430876
-
Arterial alpha-adrenergic responsiveness is decreased and SNS activity is increased in older humans
-
Hogikyan RV, Supiano MA. Arterial alpha-adrenergic responsiveness is decreased and SNS activity is increased in older humans. Am J Physiol 1994; 266: E717-24
-
(1994)
Am J Physiol
, vol.266
-
-
Hogikyan, R.V.1
Supiano, M.A.2
-
24
-
-
0028907162
-
No evidence for a general change in contractile responsiveness of the mesenteric artery with aging
-
McDonald A, MacDonald E, Fulton JD, et al. No evidence for a general change in contractile responsiveness of the mesenteric artery with aging. J Gerontol A Biol Sci Med Sci 1995; 50A: B20-5
-
(1995)
J Gerontol A Biol Sci Med Sci
, vol.50 A
-
-
McDonald, A.1
MacDonald, E.2
Fulton, J.D.3
-
25
-
-
0028907886
-
Aging and endothelial function in normotensive subjects and patients with essential hypertension
-
Taddei S, Virdis A, Mattei P, et al. Aging and endothelial function in normotensive subjects and patients with essential hypertension. Circulation 1995; 91: 1981-7
-
(1995)
Circulation
, vol.91
, pp. 1981-1987
-
-
Taddei, S.1
Virdis, A.2
Mattei, P.3
-
26
-
-
0032707717
-
Nitric oxide as a signaling molecule in the vascular system: An overview
-
Ignarro LJ, Cirino G, Casini A, et al. Nitric oxide as a signaling molecule in the vascular system: an overview. J Cardiovasc Pharmacol 1999; 34: 879-86
-
(1999)
J Cardiovasc Pharmacol
, vol.34
, pp. 879-886
-
-
Ignarro, L.J.1
Cirino, G.2
Casini, A.3
-
27
-
-
1342301460
-
An age-related decline in endothelial function is not associated with alterations in L-arginine transport in humans
-
Ahlers BA, Parnell MM, Chin-Dusting JP, et al. An age-related decline in endothelial function is not associated with alterations in L-arginine transport in humans. J Hypertens 2004; 22: 321-7
-
(2004)
J Hypertens
, vol.22
, pp. 321-327
-
-
Ahlers, B.A.1
Parnell, M.M.2
Chin-Dusting, J.P.3
-
28
-
-
11244285150
-
The markers of oxidative stress and activity of the antioxidant system in the blood of elderly patients with essential arterial hypertension
-
Kedziora-Kornatowska K, Czuczejko J, Pawluk H, et al. The markers of oxidative stress and activity of the antioxidant system in the blood of elderly patients with essential arterial hypertension. Cell Mol Biol Lett 2004; 9: 635-41
-
(2004)
Cell Mol Biol Lett
, vol.9
, pp. 635-641
-
-
Kedziora-Kornatowska, K.1
Czuczejko, J.2
Pawluk, H.3
-
29
-
-
0028673454
-
Cardiovascular reserve capacity in healthy older humans
-
Milano
-
Lakatta EG. Cardiovascular reserve capacity in healthy older humans. Aging (Milano) 1994; 6: 213-23
-
(1994)
Aging
, vol.6
, pp. 213-223
-
-
Lakatta, E.G.1
-
30
-
-
0028945831
-
Effects of aging on 24-h dynamic baroreceptor control of heart rate in ambulant subjects
-
Parati G, Frattola A, Di Rienzo M, et al. Effects of aging on 24-h dynamic baroreceptor control of heart rate in ambulant subjects. Am J Physiol 1995; 268: H1606-12
-
(1995)
Am J Physiol
, vol.268
-
-
Parati, G.1
Frattola, A.2
Di Rienzo, M.3
-
31
-
-
0033963925
-
Cardiovascular response to acute hypovolemia in relation to age: Implications for orthostasis and hemorrhage
-
Olsen H, Vernersson E, Lanne T. Cardiovascular response to acute hypovolemia in relation to age: implications for orthostasis and hemorrhage. Am J Physiol Heart Circ Physiol 2000; 278: H222-32
-
(2000)
Am J Physiol Heart Circ Physiol
, vol.278
-
-
Olsen, H.1
Vernersson, E.2
Lanne, T.3
-
32
-
-
0020034814
-
Noradrenaline release and clearance in relation to age and blood pressure in man
-
Rubin PC, Scott PJ, McLean K, et al. Noradrenaline release and clearance in relation to age and blood pressure in man. Eur J Clin Invest 1982; 12: 121-5
-
(1982)
Eur J Clin Invest
, vol.12
, pp. 121-125
-
-
Rubin, P.C.1
Scott, P.J.2
McLean, K.3
-
33
-
-
0017903818
-
Human muscle nerve sympathetic activity at rest: Relationship to blood pressure and age
-
Sundlof G, Wallin BG. Human muscle nerve sympathetic activity at rest: relationship to blood pressure and age. J Physiol 1978; 274: 621-37
-
(1978)
J Physiol
, vol.274
, pp. 621-637
-
-
Sundlof, G.1
Wallin, B.G.2
-
34
-
-
0031843972
-
Augmented cardiopulmonary and integrative sympathetic baroreflexes but attenuated peripheral vasoconstriction with age
-
Davy KP, Seals DR, Tanaka H. Augmented cardiopulmonary and integrative sympathetic baroreflexes but attenuated peripheral vasoconstriction with age. Hypertension 1998; 32: 298-304
-
(1998)
Hypertension
, vol.32
, pp. 298-304
-
-
Davy, K.P.1
Seals, D.R.2
Tanaka, H.3
-
35
-
-
0030870971
-
Orthostatic blood pressure control and ageing
-
Wing LM, Tonkin AL. Orthostatic blood pressure control and ageing. Aust N Z J Med 1997; 27: 462-6
-
(1997)
Aust N Z J Med
, vol.27
, pp. 462-466
-
-
Wing, L.M.1
Tonkin, A.L.2
-
36
-
-
0034095325
-
Norepinephrine and epinephrine responses during orthostatic intolerance in healthy elderly men
-
Gabbett T, Gass G, Gass E, et al. Norepinephrine and epinephrine responses during orthostatic intolerance in healthy elderly men. Jpn J Physiol 2000; 50: 59-66
-
(2000)
Jpn J Physiol
, vol.50
, pp. 59-66
-
-
Gabbett, T.1
Gass, G.2
Gass, E.3
-
37
-
-
0038652161
-
Effects of aging on cardiovascular responses to parasympathetic withdrawal
-
Stratton JR, Levy WC, Caldwell JH, et al. Effects of aging on cardiovascular responses to parasympathetic withdrawal. J Am Coll Cardiol 2003; 41: 2077-83
-
(2003)
J Am Coll Cardiol
, vol.41
, pp. 2077-2083
-
-
Stratton, J.R.1
Levy, W.C.2
Caldwell, J.H.3
-
38
-
-
0028031536
-
Sympathetic neural reactivity to stress does not increase with age in healthy humans
-
Ng AV, Callister R, Johnson DG, et al. Sympathetic neural reactivity to stress does not increase with age in healthy humans. Am J Physiol 1994; 267: H344-53
-
(1994)
Am J Physiol
, vol.267
-
-
Ng, A.V.1
Callister, R.2
Johnson, D.G.3
-
39
-
-
0033967116
-
Reduced baroreflex sensitivity in elderly humans is not due to efferent autonomic dysfunction
-
Lond
-
O'Mahony D, Bennett C, Green A, et al. Reduced baroreflex sensitivity in elderly humans is not due to efferent autonomic dysfunction. Clin Sci (Lond) 2000; 98: 103-10
-
(2000)
Clin Sci
, vol.98
, pp. 103-110
-
-
O'Mahony, D.1
Bennett, C.2
Green, A.3
-
40
-
-
0026539908
-
Augmented forearm vasoconstriction during dynamic exercise in healthy older men
-
Taylor JA, Hand GA, Johnson DG, et al. Augmented forearm vasoconstriction during dynamic exercise in healthy older men. Circulation 1992; 86: 1789-99
-
(1992)
Circulation
, vol.86
, pp. 1789-1799
-
-
Taylor, J.A.1
Hand, G.A.2
Johnson, D.G.3
-
41
-
-
0036209270
-
Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress
-
Esler M, Lambert G, Kaye D, et al. Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress. Biogerontology 2002; 3: 45-9
-
(2002)
Biogerontology
, vol.3
, pp. 45-49
-
-
Esler, M.1
Lambert, G.2
Kaye, D.3
-
42
-
-
0019940405
-
Age- and sex-related behaviour of gastric acid secretion at the population level
-
Kekki M, Samloff IM, Ihamaki T, et al. Age- and sex-related behaviour of gastric acid secretion at the population level. Scand J Gastroenterol 1982; 17: 737-43
-
(1982)
Scand J Gastroenterol
, vol.17
, pp. 737-743
-
-
Kekki, M.1
Samloff, I.M.2
Ihamaki, T.3
-
43
-
-
0019451134
-
Gastric emptying rate in the elderly: Implications for drug therapy
-
Evans MA, Triggs EJ, Cheung M, et al. Gastric emptying rate in the elderly: implications for drug therapy. J Am Geriatr Soc 1981; 29: 201-5
-
(1981)
J Am Geriatr Soc
, vol.29
, pp. 201-205
-
-
Evans, M.A.1
Triggs, E.J.2
Cheung, M.3
-
44
-
-
0000261394
-
The effect of increasing age on the distribution of peripheral blood flow in man
-
Bender AD. The effect of increasing age on the distribution of peripheral blood flow in man. J Am Geriatr Soc 1965; 13: 192-8
-
(1965)
J Am Geriatr Soc
, vol.13
, pp. 192-198
-
-
Bender, A.D.1
-
45
-
-
0022559689
-
Ageing and smallbowel mucosa: A morphometric study
-
Corazza GR, Frazzoni M, Gatto MR, et al. Ageing and smallbowel mucosa: a morphometric study. Gerontology 1986; 32: 60-5
-
(1986)
Gerontology
, vol.32
, pp. 60-65
-
-
Corazza, G.R.1
Frazzoni, M.2
Gatto, M.R.3
-
47
-
-
0026750005
-
The patterns of motility are maintained in the human small intestine throughout the process of aging
-
Husebye E, Engedal K. The patterns of motility are maintained in the human small intestine throughout the process of aging. Scand J Gastroenterol 1992; 27: 397-404
-
(1992)
Scand J Gastroenterol
, vol.27
, pp. 397-404
-
-
Husebye, E.1
Engedal, K.2
-
49
-
-
0018386403
-
The effect of ageing on the hepatic clearance of propranolol
-
Castleden CM, George CF. The effect of ageing on the hepatic clearance of propranolol. Br J Clin Pharmacol 1979; 7: 49-54
-
(1979)
Br J Clin Pharmacol
, vol.7
, pp. 49-54
-
-
Castleden, C.M.1
George, C.F.2
-
51
-
-
0021737469
-
An overview of the clinical pharmacology of enalapril
-
Davies RO, Gomez HJ, Irvin JD, et al. An overview of the clinical pharmacology of enalapril. Br J Clin Pharmacol 1984; 18 Suppl. 2: 215S-29S
-
(1984)
Br J Clin Pharmacol
, vol.18
, Issue.2 SUPPL.
-
-
Davies, R.O.1
Gomez, H.J.2
Irvin, J.D.3
-
52
-
-
0025851257
-
Perindopril: A review of its pharmacological properties and therapeutic use in cardiovascular disorders
-
Todd PA, Fitton A. Perindopril: a review of its pharmacological properties and therapeutic use in cardiovascular disorders. Drugs 1991; 42: 90-114
-
(1991)
Drugs
, vol.42
, pp. 90-114
-
-
Todd, P.A.1
Fitton, A.2
-
53
-
-
2442543344
-
P-glycoprotein function in the elderly
-
Brenner SS, Klotz U. P-glycoprotein function in the elderly. Eur J Clin Pharmacol 2004; 60: 97-102
-
(2004)
Eur J Clin Pharmacol
, vol.60
, pp. 97-102
-
-
Brenner, S.S.1
Klotz, U.2
-
54
-
-
0021868717
-
Body composition in elderly people: II. Comparison of measured and predicted body composition in healthy elderly subjects
-
Fulop Jr T, Worum I, Csongor J, et al. Body composition in elderly people: II. Comparison of measured and predicted body composition in healthy elderly subjects. Gerontology 1985; 31: 150-7
-
(1985)
Gerontology
, vol.31
, pp. 150-157
-
-
Fulop Jr., T.1
Worum, I.2
Csongor, J.3
-
55
-
-
0021907243
-
Body composition in elderly people: I. Determination of body composition by multiisotope method and the elimination kinetics of these isotopes in healthy elderly subjects
-
Fulop Jr T, Worum I, Csongor J, et al. Body composition in elderly people: I. Determination of body composition by multiisotope method and the elimination kinetics of these isotopes in healthy elderly subjects. Gerontology 1985; 31: 6-14
-
(1985)
Gerontology
, vol.31
, pp. 6-14
-
-
Fulop Jr., T.1
Worum, I.2
Csongor, J.3
-
56
-
-
0018629536
-
Digoxin in the elderly: Pharmacokinetic consequences of old age
-
Cusack B, Kelly J, O'Malley K, et al. Digoxin in the elderly: pharmacokinetic consequences of old age. Clin Pharmacol Ther 1979; 25: 772-6
-
(1979)
Clin Pharmacol Ther
, vol.25
, pp. 772-776
-
-
Cusack, B.1
Kelly, J.2
O'Malley, K.3
-
57
-
-
0032431232
-
Age effect on fibrinogen and albumin synthesis in humans
-
Fu A, Sreekumaran NK. Age effect on fibrinogen and albumin synthesis in humans. Am J Physiol 1998; 275: E1023-30
-
(1998)
Am J Physiol
, vol.275
-
-
Fu, A.1
Sreekumaran, N.K.2
-
58
-
-
0036218554
-
Changes in plasma protein binding have little clinical relevance
-
Benet LZ, Hoener BA. Changes in plasma protein binding have little clinical relevance. Clin Pharmacol Ther 2002; 71: 115-21
-
(2002)
Clin Pharmacol Ther
, vol.71
, pp. 115-121
-
-
Benet, L.Z.1
Hoener, B.A.2
-
59
-
-
0023230363
-
Relationship between vascular disease and age-associated changes in the human kidney
-
Kasiske BL. Relationship between vascular disease and age-associated changes in the human kidney. Kidney Int 1987; 31: 1153-9
-
(1987)
Kidney Int
, vol.31
, pp. 1153-1159
-
-
Kasiske, B.L.1
-
60
-
-
0024469548
-
Age dependence of renal function: Clearance of iohexol and p-amino hippurate in healthy males
-
Back SE, Ljungberg B, Nilsson-Ehle I, et al. Age dependence of renal function: clearance of iohexol and p-amino hippurate in healthy males. Scand J Clin Lab Invest 1989; 49: 641-6
-
(1989)
Scand J Clin Lab Invest
, vol.49
, pp. 641-646
-
-
Back, S.E.1
Ljungberg, B.2
Nilsson-Ehle, I.3
-
61
-
-
0017230772
-
The effect of age on creatinine clearance in men: A cross-sectional and longitudinal study
-
Rowe JW, Andres R, Tobin JD, et al. The effect of age on creatinine clearance in men: a cross-sectional and longitudinal study. J Gerontol 1976; 31: 155-63
-
(1976)
J Gerontol
, vol.31
, pp. 155-163
-
-
Rowe, J.W.1
Andres, R.2
Tobin, J.D.3
-
62
-
-
0025319682
-
Amiloride disposition in geriatric patients: Importance of renal function
-
Somogyi A, Hewson D, Muirhead M, et al. Amiloride disposition in geriatric patients: importance of renal function. Br J Clin Pharmacol 1990; 29: 1-8
-
(1990)
Br J Clin Pharmacol
, vol.29
, pp. 1-8
-
-
Somogyi, A.1
Hewson, D.2
Muirhead, M.3
-
63
-
-
0025126118
-
Understanding digoxin use in the elderly patient
-
Tsang P, Gerson B. Understanding digoxin use in the elderly patient. Clin Lab Med 1990; 10: 479-92
-
(1990)
Clin Lab Med
, vol.10
, pp. 479-492
-
-
Tsang, P.1
Gerson, B.2
-
64
-
-
0022352999
-
A comparison of the pharmacokinetics of atenolol, metoprolol, oxprenolol and propranolol in elderly hypertensive and young healthy subjects
-
Rigby JW, Scott AK, Hawksworth GM, et al. A comparison of the pharmacokinetics of atenolol, metoprolol, oxprenolol and propranolol in elderly hypertensive and young healthy subjects. Br J Clin Pharmacol 1985; 20: 327-31
-
(1985)
Br J Clin Pharmacol
, vol.20
, pp. 327-331
-
-
Rigby, J.W.1
Scott, A.K.2
Hawksworth, G.M.3
-
65
-
-
0032986470
-
Renal handling of drugs in the healthy elderly. Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged
-
Fliser D, Bischoff I, Hanses A, et al. Renal handling of drugs in the healthy elderly. Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged. Eur J Clin Pharmacol 1999; 55: 205-11
-
(1999)
Eur J Clin Pharmacol
, vol.55
, pp. 205-211
-
-
Fliser, D.1
Bischoff, I.2
Hanses, A.3
-
66
-
-
23144447473
-
Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: A position statement
-
Mathew TH. Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: a position statement. Med J Aust 2005; 183: 138-41
-
(2005)
Med J Aust
, vol.183
, pp. 138-141
-
-
Mathew, T.H.1
-
67
-
-
0016916438
-
Prediction of creatinine clearance from serum creatinine
-
Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16: 31-41
-
(1976)
Nephron
, vol.16
, pp. 31-41
-
-
Cockcroft, D.W.1
Gault, M.H.2
-
68
-
-
3042730147
-
Validation of the Modification of Diet in Renal Disease formula for estimating GFR with special emphasis on calibration of the serum creati-nine assay
-
Hallan S, Asberg A, Lindberg M, et al. Validation of the Modification of Diet in Renal Disease formula for estimating GFR with special emphasis on calibration of the serum creati-nine assay. Am J Kidney Dis 2004; 44: 84-93
-
(2004)
Am J Kidney Dis
, vol.44
, pp. 84-93
-
-
Hallan, S.1
Asberg, A.2
Lindberg, M.3
-
70
-
-
0035695389
-
Liver function and phase I drug metabolism in the elderly: A paradox
-
Schmucker DL. Liver function and phase I drug metabolism in the elderly: a paradox. Drugs Aging 2001; 18: 837-51
-
(2001)
Drugs Aging
, vol.18
, pp. 837-851
-
-
Schmucker, D.L.1
-
71
-
-
0023792660
-
Comparison of paracetamol metabolism in young adult and elderly males
-
Miners JO, Penhall R, Robson RA, et al. Comparison of paracetamol metabolism in young adult and elderly males. Eur J Clin Pharmacol 1988; 35: 157-60
-
(1988)
Eur J Clin Pharmacol
, vol.35
, pp. 157-160
-
-
Miners, J.O.1
Penhall, R.2
Robson, R.A.3
-
73
-
-
0032767581
-
In-vivo indices of enzyme activity: The effect of renal impairment on the assessment of CYP2D6 activity
-
Rostami-Hodjegan A, Kroemer HK, Tucker GT. In-vivo indices of enzyme activity: the effect of renal impairment on the assessment of CYP2D6 activity. Pharmacogenetics 1999; 9: 277-86
-
(1999)
Pharmacogenetics
, vol.9
, pp. 277-286
-
-
Rostami-Hodjegan, A.1
Kroemer, H.K.2
Tucker, G.T.3
-
74
-
-
0034023147
-
Effect of chronic renal failure on the disposition of highly hepatically metabolized drugs
-
Yuan R, Venitz J. Effect of chronic renal failure on the disposition of highly hepatically metabolized drugs. Int J Clin Pharmacol Ther 2000; 38: 245-53
-
(2000)
Int J Clin Pharmacol Ther
, vol.38
, pp. 245-253
-
-
Yuan, R.1
Venitz, J.2
-
75
-
-
0028859061
-
Pharmacokinetics and pharmacodynamics of the diuretic bumetanide in the elderly
-
Oberbauer R, Krivanek P, Turnheim K. Pharmacokinetics and pharmacodynamics of the diuretic bumetanide in the elderly. Clin Pharmacol Ther 1995; 57: 42-51
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 42-51
-
-
Oberbauer, R.1
Krivanek, P.2
Turnheim, K.3
-
76
-
-
0020617892
-
The pharmacokinetics of frusemide are influenced by age
-
Andreasen F, Hansen U, Husted SE, et al. The pharmacokinetics of frusemide are influenced by age. Br J Clin Pharmacol 1983; 16: 391-7
-
(1983)
Br J Clin Pharmacol
, vol.16
, pp. 391-397
-
-
Andreasen, F.1
Hansen, U.2
Husted, S.E.3
-
77
-
-
0022513492
-
Absorption and disposition of two combination formulations of hydrochloroth-iazide and triamterene: Influence of age and renal function
-
Williams RL, Thornhill MD, Upton RA, et al. Absorption and disposition of two combination formulations of hydrochloroth-iazide and triamterene: influence of age and renal function. Clin Pharmacol Ther 1986; 40: 226-32
-
(1986)
Clin Pharmacol Ther
, vol.40
, pp. 226-232
-
-
Williams, R.L.1
Thornhill, M.D.2
Upton, R.A.3
-
78
-
-
0023143622
-
A comparative study of the pharmacokinetics and pharmacodynamics of atenolol, hydrochlorothiazide and amiloride in normal young and elderly subjects and elderly hypertensive patients
-
Sabanathan K, Castleden CM, Adam HK, et al. A comparative study of the pharmacokinetics and pharmacodynamics of atenolol, hydrochlorothiazide and amiloride in normal young and elderly subjects and elderly hypertensive patients. Eur J Clin Pharmacol 1987; 32: 53-60
-
(1987)
Eur J Clin Pharmacol
, vol.32
, pp. 53-60
-
-
Sabanathan, K.1
Castleden, C.M.2
Adam, H.K.3
-
79
-
-
0024407734
-
The pharmacokinetics of amiloride-hydrochlorothiazide combination in the young and elderly
-
Ismail Z, Triggs EJ, Smithurst BA, et al. The pharmacokinetics of amiloride-hydrochlorothiazide combination in the young and elderly. Eur J Clin Pharmacol 1989; 37: 167-71
-
(1989)
Eur J Clin Pharmacol
, vol.37
, pp. 167-171
-
-
Ismail, Z.1
Triggs, E.J.2
Smithurst, B.A.3
-
80
-
-
0021738021
-
Comparison of plasma levels of canrenone and metabolites after base hydrolysis in young and elderly subjects following single and multiple doses of spironolactone
-
Ho PC, Bourne DW, Triggs EJ, et al. Comparison of plasma levels of canrenone and metabolites after base hydrolysis in young and elderly subjects following single and multiple doses of spironolactone. Eur J Clin Pharmacol 1984; 27: 435-9
-
(1984)
Eur J Clin Pharmacol
, vol.27
, pp. 435-439
-
-
Ho, P.C.1
Bourne, D.W.2
Triggs, E.J.3
-
81
-
-
0021227578
-
The influence of age on renal and extrarenal effects of frusemide
-
Andreasen F, Hansen U, Husted SE, et al. The influence of age on renal and extrarenal effects of frusemide. Br J Clin Pharmacol 1984; 18: 65-74
-
(1984)
Br J Clin Pharmacol
, vol.18
, pp. 65-74
-
-
Andreasen, F.1
Hansen, U.2
Husted, S.E.3
-
82
-
-
0021733895
-
The effect of ageing on the response to frusemide in normal subjects
-
Chaudhry AY, Bing RF, Castleden CM, et al. The effect of ageing on the response to frusemide in normal subjects. Eur J Clin Pharmacol 1984; 27: 303-6
-
(1984)
Eur J Clin Pharmacol
, vol.27
, pp. 303-306
-
-
Chaudhry, A.Y.1
Bing, R.F.2
Castleden, C.M.3
-
84
-
-
0021714880
-
Once daily in-dapamide in the treatment of the elderly and young hypertensive
-
Rowlands DB, Glover DR, Young MA, et al. Once daily in-dapamide in the treatment of the elderly and young hypertensive. Eur J Clin Pharmacol 1984; 27: 397-405
-
(1984)
Eur J Clin Pharmacol
, vol.27
, pp. 397-405
-
-
Rowlands, D.B.1
Glover, D.R.2
Young, M.A.3
-
85
-
-
0344373794
-
Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
-
Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288: 2981-97
-
(2002)
JAMA
, vol.288
, pp. 2981-2997
-
-
-
86
-
-
0347423198
-
Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
-
Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003; 42: 1206-52
-
(2003)
Hypertension
, vol.42
, pp. 1206-1252
-
-
Chobanian, A.V.1
Bakris, G.L.2
Black, H.R.3
-
87
-
-
0035968623
-
Randomised trial of a perindopril-based blood-pressure-lower-ing regimen among 6,105 individuals with previous stroke or transient ischaemic attack
-
Randomised trial of a perindopril-based blood-pressure-lower-ing regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001; 358: 1033-41
-
(2001)
Lancet
, vol.358
, pp. 1033-1041
-
-
-
88
-
-
2342631217
-
Effect of antihypertensive agents on quality of life in the elderly
-
Fogari R, Zoppi A. Effect of antihypertensive agents on quality of life in the elderly. Drugs Aging 2004; 21: 377-93
-
(2004)
Drugs Aging
, vol.21
, pp. 377-393
-
-
Fogari, R.1
Zoppi, A.2
-
89
-
-
0042367597
-
Very-low-dose combination: A first-line choice for the treatment of hypertension?
-
Waeber B. Very-low-dose combination: a first-line choice for the treatment of hypertension? J Hypertens Suppl 2003; 21 Suppl. 3: S3-10
-
(2003)
J Hypertens Suppl
, vol.21
, Issue.3 SUPPL.
-
-
Waeber, B.1
-
90
-
-
20644457372
-
Prescribing patterns of diuretics in multi-drug antihypertensive regimens
-
Greenwich
-
Singh H, Johnson ML. Prescribing patterns of diuretics in multi-drug antihypertensive regimens. J Clin Hypertens (Greenwich) 2005; 7: 81-7
-
(2005)
J Clin Hypertens
, vol.7
, pp. 81-87
-
-
Singh, H.1
Johnson, M.L.2
-
91
-
-
17144388969
-
Diuretic usage in heart failure: A continuing conundrum in 2005
-
Gupta S, Neyses L. Diuretic usage in heart failure: a continuing conundrum in 2005. Eur Heart J 2005; 26: 644-9
-
(2005)
Eur Heart J
, vol.26
, pp. 644-649
-
-
Gupta, S.1
Neyses, L.2
-
92
-
-
17144430936
-
Reassessing treatment of acute heart failure syndromes: The ADHERE Registry
-
Gheorghiade M, Filippatos G. Reassessing treatment of acute heart failure syndromes: the ADHERE Registry. Eur Heart J 2005; 7 Suppl. B: B13-9
-
(2005)
Eur Heart J
, vol.7
, Issue.SUPPL. B
-
-
Gheorghiade, M.1
Filippatos, G.2
-
93
-
-
0033517302
-
The effect of spironolactone on morbidity and mortality in patients with severe heart failure
-
Randomized Aldactone Evaluation Study Investigators
-
Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999; 341: 709-17
-
(1999)
N Engl J Med
, vol.341
, pp. 709-717
-
-
Pitt, B.1
Zannad, F.2
Remme, W.J.3
-
94
-
-
0033577487
-
Mineralocorticoid hypertension
-
Stewart PM. Mineralocorticoid hypertension. Lancet 1999; 353: 1341-7
-
(1999)
Lancet
, vol.353
, pp. 1341-1347
-
-
Stewart, P.M.1
-
95
-
-
3042731163
-
Serum aldosterone and the incidence of hypertension in nonhypertensive persons
-
Vasan RS, Evans JC, Larson MG, et al. Serum aldosterone and the incidence of hypertension in nonhypertensive persons. N Engl J Med 2004; 351: 33-41
-
(2004)
N Engl J Med
, vol.351
, pp. 33-41
-
-
Vasan, R.S.1
Evans, J.C.2
Larson, M.G.3
-
96
-
-
3442886513
-
Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study
-
Juurlink DN, Mamdani MM, Lee DS, et al. Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. N Engl J Med 2004; 351: 543-51
-
(2004)
N Engl J Med
, vol.351
, pp. 543-551
-
-
Juurlink, D.N.1
Mamdani, M.M.2
Lee, D.S.3
-
97
-
-
0020371875
-
Atenolol disposition in young and elderly subjects
-
Rubin PC, Scott PJ, McLean K, et al. Atenolol disposition in young and elderly subjects. Br J Clin Pharmacol 1982; 13: 235-7
-
(1982)
Br J Clin Pharmacol
, vol.13
, pp. 235-237
-
-
Rubin, P.C.1
Scott, P.J.2
McLean, K.3
-
98
-
-
0029113448
-
Effect of aging on atenolol pharmacokinetics and pharmacodynamics
-
Sowinski KM, Forrest A, Wilton JH, et al. Effect of aging on atenolol pharmacokinetics and pharmacodynamics. J Clin Pharmacol 1995; 35: 807-14
-
(1995)
J Clin Pharmacol
, vol.35
, pp. 807-814
-
-
Sowinski, K.M.1
Forrest, A.2
Wilton, J.H.3
-
99
-
-
0022881326
-
Beta-blocking effect and pharmacokinetics of pindolol in young and elderly hypertensive patients
-
Gretzer I, Alvan G, Duner H, et al. Beta-blocking effect and pharmacokinetics of pindolol in young and elderly hypertensive patients. Eur J Clin Pharmacol 1986; 31: 415-8
-
(1986)
Eur J Clin Pharmacol
, vol.31
, pp. 415-418
-
-
Gretzer, I.1
Alvan, G.2
Duner, H.3
-
100
-
-
0020434588
-
Effects of age and smoking on the pharmacokinetics of pindolol and propranolol
-
Hitzenberger G, Fitscha P, Beveridge T, et al. Effects of age and smoking on the pharmacokinetics of pindolol and propranolol. Br J Clin Pharmacol 1982; 13: 217S-22S
-
(1982)
Br J Clin Pharmacol
, vol.13
-
-
Hitzenberger, G.1
Fitscha, P.2
Beveridge, T.3
-
101
-
-
0018905194
-
Pharmacokinetics and pharmacodynamics in young normal and elderly hypertensive subjects: A study using sotalol as a model drug
-
Ishizaki T, Hirayama H, Tawara K, et al. Pharmacokinetics and pharmacodynamics in young normal and elderly hypertensive subjects: a study using sotalol as a model drug. J Pharmacol Exp Ther 1980; 212: 173-81
-
(1980)
J Pharmacol Exp Ther
, vol.212
, pp. 173-181
-
-
Ishizaki, T.1
Hirayama, H.2
Tawara, K.3
-
102
-
-
0020554374
-
Bioavailability of metoprolol in young adults and the elderly, with additional studies on the effects of metoclopramide and probanthine
-
Briant RH, Dorrington RE, Ferry DG, et al. Bioavailability of metoprolol in young adults and the elderly, with additional studies on the effects of metoclopramide and probanthine. Eur J Clin Pharmacol 1983; 25: 353-6
-
(1983)
Eur J Clin Pharmacol
, vol.25
, pp. 353-356
-
-
Briant, R.H.1
Dorrington, R.E.2
Ferry, D.G.3
-
104
-
-
0019431991
-
The effect of age on the pharmacokinetics of metoprolol and its metabolites
-
Quarterman CP, Kendall MJ, Jack DB. The effect of age on the pharmacokinetics of metoprolol and its metabolites. Br J Clin Pharmacol 1981; 11: 287-94
-
(1981)
Br J Clin Pharmacol
, vol.11
, pp. 287-294
-
-
Quarterman, C.P.1
Kendall, M.J.2
Jack, D.B.3
-
105
-
-
0025613596
-
Pharmacokinetics of carvedilol in older and younger patients
-
Morgan T, Anderson A, Cripps J, et al. Pharmacokinetics of carvedilol in older and younger patients. J Hum Hypertens 1990; 4: 709-15
-
(1990)
J Hum Hypertens
, vol.4
, pp. 709-715
-
-
Morgan, T.1
Anderson, A.2
Cripps, J.3
-
106
-
-
0023635004
-
Comparison in young and elderly patients of pharmacodynamics and disposi-tion of labetalol in systemic hypertension
-
Abernethy DR, Schwartz JB, Plachetka JR, et al. Comparison in young and elderly patients of pharmacodynamics and disposi-tion of labetalol in systemic hypertension. Am J Cardiol 1987; 60: 697-702
-
(1987)
Am J Cardiol
, vol.60
, pp. 697-702
-
-
Abernethy, D.R.1
Schwartz, J.B.2
Plachetka, J.R.3
-
107
-
-
0025318845
-
Pharmacokinetics and pharmacodynamics of labetalol in elderly and young hypertensive patients following single and multiple doses
-
Rocci Jr ML, Vlasses PH, Cressman MD, et al. Pharmacokinet-ics and pharmacodynamics of labetalol in elderly and young hypertensive patients following single and multiple doses. Pharmacotherapy 1990; 10: 92-9
-
(1990)
Pharmacotherapy
, vol.10
, pp. 92-99
-
-
Rocci Jr., M.L.1
Vlasses, P.H.2
Cressman, M.D.3
-
108
-
-
0025344429
-
Effects of age on the protein binding and disposition of propranolol stereoisomers
-
Lalonde RL, Tenero DM, Burlew BS, et al. Effects of age on the protein binding and disposition of propranolol stereoisomers. Clin Pharmacol Ther 1990; 47: 447-55
-
(1990)
Clin Pharmacol Ther
, vol.47
, pp. 447-455
-
-
Lalonde, R.L.1
Tenero, D.M.2
Burlew, B.S.3
-
109
-
-
0026500071
-
Lack of effect of ageing on the stereochemical disposition of propranolol
-
Zhou HH, Whelan E, Wood AJ. Lack of effect of ageing on the stereochemical disposition of propranolol. Br J Clin Pharmacol 1992; 33: 121-3
-
(1992)
Br J Clin Pharmacol
, vol.33
, pp. 121-123
-
-
Zhou, H.H.1
Whelan, E.2
Wood, A.J.3
-
110
-
-
0023819386
-
The effect of ageing on the disposition of nifedipine and atenolol
-
Scott M, Castleden CM, Adam HK, et al. The effect of ageing on the disposition of nifedipine and atenolol. Br J Clin Pharmacol 1988; 25: 289-96
-
(1988)
Br J Clin Pharmacol
, vol.25
, pp. 289-296
-
-
Scott, M.1
Castleden, C.M.2
Adam, H.K.3
-
111
-
-
0024232242
-
Hemodynamic effects of labetalol in young and older adult hypertensives
-
Buell JC, Eliot RS, Plachetka JR, et al. Hemodynamic effects of labetalol in young and older adult hypertensives. J Clin Pharmacol 1988; 28: 327-31
-
(1988)
J Clin Pharmacol
, vol.28
, pp. 327-331
-
-
Buell, J.C.1
Eliot, R.S.2
Plachetka, J.R.3
-
112
-
-
0025109736
-
Altered beta-adrenergic sensitivity and protein binding to 1-propranolol in the elderly
-
Tenero DM, Bottorff MB, Burlew BS, et al. Altered beta-adrenergic sensitivity and protein binding to 1-propranolol in the elderly. J Cardiovasc Pharmacol 1990; 16: 702-7
-
(1990)
J Cardiovasc Pharmacol
, vol.16
, pp. 702-707
-
-
Tenero, D.M.1
Bottorff, M.B.2
Burlew, B.S.3
-
113
-
-
0026504977
-
Age and beta-adrenergic receptor sensitivity to S(-)- And R,S(+/-)-propranolol in humans
-
Colangelo PM, Blouin RA, Steinmetz JE, et al. Age and beta-adrenergic receptor sensitivity to S(-)- and R,S(+/-)-propranolol in humans. Clin Pharmacol Ther 1992; 51: 549-54
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 549-554
-
-
Colangelo, P.M.1
Blouin, R.A.2
Steinmetz, J.E.3
-
114
-
-
0037527647
-
European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension
-
European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21: 1011-1053
-
(2003)
J Hypertens
, vol.21
, pp. 1011-1053
-
-
-
115
-
-
0035978763
-
Effect of carvedilol on survival in severe chronic heart failure
-
Packer M, Coats AJ, Fowler MB, et al. Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med 2001; 344: 1651-8
-
(2001)
N Engl J Med
, vol.344
, pp. 1651-1658
-
-
Packer, M.1
Coats, A.J.2
Fowler, M.B.3
-
116
-
-
0033549290
-
Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)
-
Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999; 353: 2001-7
-
(1999)
Lancet
, vol.353
, pp. 2001-2007
-
-
-
117
-
-
3242889817
-
Efficacy, safety and tolerability of beta-adrenergic blockade with metoprolol CR/XL in elderly patients with heart failure
-
Deedwania PC, Gottlieb S, Ghali JK, et al. Efficacy, safety and tolerability of beta-adrenergic blockade with metoprolol CR/XL in elderly patients with heart failure. Eur Heart J 2004; 25: 1300-9
-
(2004)
Eur Heart J
, vol.25
, pp. 1300-1309
-
-
Deedwania, P.C.1
Gottlieb, S.2
Ghali, J.K.3
-
118
-
-
0024241790
-
A comparison of the disposition of single oral doses of amlodipine in young and elderly subjects
-
Elliott HL, Meredith PA, Reid JL, et al. A comparison of the disposition of single oral doses of amlodipine in young and elderly subjects. J Cardiovasc Pharmacol 1988; 12 Suppl. 7: S64-6
-
(1988)
J Cardiovasc Pharmacol
, vol.12
, Issue.7 SUPPL.
-
-
Elliott, H.L.1
Meredith, P.A.2
Reid, J.L.3
-
119
-
-
0028349951
-
An overview of the pharmacokinetics and pharmacodynamics of amlodipine in elderly persons with systemic hypertension
-
Abernethy DR. An overview of the pharmacokinetics and pharmacodynamics of amlodipine in elderly persons with systemic hypertension. Am J Cardiol 1994; 73: 10A-7A
-
(1994)
Am J Cardiol
, vol.73
-
-
Abernethy, D.R.1
-
120
-
-
0023747525
-
Pharmacokinetics and blood pressure effects of felodipine in elderly hypertensive patients: A comparison with young healthy subjects
-
Landahl S, Edgar B, Gabrielsson M, et al. Pharmacokinetics and blood pressure effects of felodipine in elderly hypertensive patients: a comparison with young healthy subjects. Clin Pharmacokinet 1988; 14: 374-83
-
(1988)
Clin Pharmacokinet
, vol.14
, pp. 374-383
-
-
Landahl, S.1
Edgar, B.2
Gabrielsson, M.3
-
121
-
-
0023918735
-
Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine
-
Robertson DR, Waller DG, Renwick AG, et al. Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine. Br J Clin Pharmacol 1988; 25: 297-305
-
(1988)
Br J Clin Pharmacol
, vol.25
, pp. 297-305
-
-
Robertson, D.R.1
Waller, D.G.2
Renwick, A.G.3
-
122
-
-
0023653611
-
Acute and chronic studies of diltiazem in elderly versus young hypertensive patients
-
Abernethy DR, Montamat SC. Acute and chronic studies of diltiazem in elderly versus young hypertensive patients. Am J Cardiol 1987; 60: 116I-20I
-
(1987)
Am J Cardiol
, vol.60
-
-
Abernethy, D.R.1
Montamat, S.C.2
-
123
-
-
0024358677
-
Calcium antagonists in geriatric patients: Diltiazem in elderly persons with hypertension
-
Montamat SC, Abernethy DR. Calcium antagonists in geriatric patients: diltiazem in elderly persons with hypertension. Clin Pharmacol Ther 1989; 45: 682-91
-
(1989)
Clin Pharmacol Ther
, vol.45
, pp. 682-691
-
-
Montamat, S.C.1
Abernethy, D.R.2
-
124
-
-
0030000311
-
Multicenter studies on the pharmacokinetic profile of sustained-release oral diltiazem (300 mg) after once a day repeated administration: Influence of age
-
Bianchetti G, Billy S, Ascalone V, et al. Multicenter studies on the pharmacokinetic profile of sustained-release oral diltiazem (300 mg) after once a day repeated administration: influence of age. Int J Clin Pharmacol Ther 1996; 34: 195-201
-
(1996)
Int J Clin Pharmacol Ther
, vol.34
, pp. 195-201
-
-
Bianchetti, G.1
Billy, S.2
Ascalone, V.3
-
125
-
-
0025134766
-
Aging alters verapamil elimination and dynamics: Single dose and steady-state responses
-
Schwartz JB. Aging alters verapamil elimination and dynamics: single dose and steady-state responses. J Pharmacol Exp Ther 1990; 255: 364-73
-
(1990)
J Pharmacol Exp Ther
, vol.255
, pp. 364-373
-
-
Schwartz, J.B.1
-
126
-
-
0028357260
-
Aging of women alters S-verapamil pharmacokinetics and pharmacodynamics
-
Schwartz JB, Capili H, Daugherty J. Aging of women alters S-verapamil pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther 1994; 55: 509-17
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 509-517
-
-
Schwartz, J.B.1
Capili, H.2
Daugherty, J.3
-
127
-
-
0028848415
-
Age and gender related changes in stereoselective pharmacokinetics and pharmacodynamics of verapamil and norverapamil
-
Gupta SK, Atkinson L, Tu T, et al. Age and gender related changes in stereoselective pharmacokinetics and pharmacodynamics of verapamil and norverapamil. Br J Clin Pharmacol 1995; 40: 325-31
-
(1995)
Br J Clin Pharmacol
, vol.40
, pp. 325-331
-
-
Gupta, S.K.1
Atkinson, L.2
Tu, T.3
-
128
-
-
0027420653
-
The effects of age and gender on the stereoselective pharmacokinetics of verapamil
-
Sasaki M, Tateishi T, Ebihara A. The effects of age and gender on the stereoselective pharmacokinetics of verapamil. Clin Pharmacol Ther 1993; 54: 278-85
-
(1993)
Clin Pharmacol Ther
, vol.54
, pp. 278-285
-
-
Sasaki, M.1
Tateishi, T.2
Ebihara, A.3
-
129
-
-
0024357731
-
Verapamil disposition and cardiovascular effects in elderly patients after single intravenous and oral doses
-
Carosella L, Menichelli P, Alimenti M, et al. Verapamil disposition and cardiovascular effects in elderly patients after single intravenous and oral doses. Cardiovasc Drugs Ther 1989; 3: 417-25
-
(1989)
Cardiovasc Drugs Ther
, vol.3
, pp. 417-425
-
-
Carosella, L.1
Menichelli, P.2
Alimenti, M.3
-
130
-
-
0025999834
-
The influence of age on the pharmacokinetics of verapamil
-
Ahmed JH, Meredith PA, Elliott HL. The influence of age on the pharmacokinetics of verapamil. Pharmacol Res 1991; 24: 227-33
-
(1991)
Pharmacol Res
, vol.24
, pp. 227-233
-
-
Ahmed, J.H.1
Meredith, P.A.2
Elliott, H.L.3
-
131
-
-
0030004863
-
Sex- and age-related antihypertensive effects of amlodipine
-
The Amlodipine Cardiovascular Community Trial Study Group
-
Kloner RA, Sowers JR, DiBona GF, et al. Sex- and age-related antihypertensive effects of amlodipine. The Amlodipine Cardiovascular Community Trial Study Group. Am J Cardiol 1996; 77: 713-22
-
(1996)
Am J Cardiol
, vol.77
, pp. 713-722
-
-
Kloner, R.A.1
Sowers, J.R.2
DiBona, G.F.3
-
132
-
-
0025837330
-
Effect of nifedipine tablets on ambulatory blood pressure in patients aged less than 60 and greater than 65 years with systemic hypertension
-
Kuwajima I, Suzuki Y, Shimosawa T, et al. Effect of nifedipine tablets on ambulatory blood pressure in patients aged less than 60 and greater than 65 years with systemic hypertension. Am J Cardiol 1991; 68: 1351-6
-
(1991)
Am J Cardiol
, vol.68
, pp. 1351-1356
-
-
Kuwajima, I.1
Suzuki, Y.2
Shimosawa, T.3
-
134
-
-
0023225515
-
Age and the pharmacokinetics and pharmacodynamics of chronic enalapril treatment
-
Lees KR, Reid JL. Age and the pharmacokinetics and pharmacodynamics of chronic enalapril treatment. Clin Pharmacol Ther 1987; 41: 597-602
-
(1987)
Clin Pharmacol Ther
, vol.41
, pp. 597-602
-
-
Lees, K.R.1
Reid, J.L.2
-
135
-
-
0023689824
-
Influence of age on the pharmacokinetics and pharmacodynamics of perindopril
-
Lees KR, Green ST, Reid JL. Influence of age on the pharmacokinetics and pharmacodynamics of perindopril. Clin Pharmacol Ther 1988; 44: 418-25
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 418-425
-
-
Lees, K.R.1
Green, S.T.2
Reid, J.L.3
-
136
-
-
0027244446
-
The effects of age on the pharmacokinetics and pharmacodynamics of single oral doses of benazepril and enalapril
-
MacDonald NJ, Sioufi A, Howie CA, et al. The effects of age on the pharmacokinetics and pharmacodynamics of single oral doses of benazepril and enalapril. Br J Clin Pharmacol 1993; 36: 205-9
-
(1993)
Br J Clin Pharmacol
, vol.36
, pp. 205-209
-
-
MacDonald, N.J.1
Sioufi, A.2
Howie, C.A.3
-
137
-
-
0023036998
-
Age and the pharmacokinetics of angiotensin converting enzyme inhibitors enalapril and enalaprilat
-
Hockings N, Ajayi AA, Reid JL. Age and the pharmacokinetics of angiotensin converting enzyme inhibitors enalapril and enalaprilat. Br J Clin Pharmacol 1986; 21: 341-8
-
(1986)
Br J Clin Pharmacol
, vol.21
, pp. 341-348
-
-
Hockings, N.1
Ajayi, A.A.2
Reid, J.L.3
-
138
-
-
0023597434
-
Pharmacokinetics of lisinopril (MK521) in healthy young and elderly subjects and in elderly patients with cardiac failure
-
Gautam PC, Vargas E, Lye M. Pharmacokinetics of lisinopril (MK521) in healthy young and elderly subjects and in elderly patients with cardiac failure. J Pharm Pharmacol 1987; 39: 929-31
-
(1987)
J Pharm Pharmacol
, vol.39
, pp. 929-931
-
-
Gautam, P.C.1
Vargas, E.2
Lye, M.3
-
140
-
-
0028129525
-
Pharmacokinetics and pharmacodynamics of trandolapril after repeated administration of 2 mg to young and elderly patients with mild-to-moderate hypertension
-
Arner P, Wade A, Engfeldt P, et al. Pharmacokinetics and pharmacodynamics of trandolapril after repeated administration of 2 mg to young and elderly patients with mild-to-moderate hypertension. J Cardiovasc Pharmacol 1994; 23 Suppl. 4: S44-9
-
(1994)
J Cardiovasc Pharmacol
, vol.23
, Issue.4 SUPPL.
-
-
Arner, P.1
Wade, A.2
Engfeldt, P.3
-
141
-
-
0024561555
-
The antihyper-tensive response to lisinopril: The effect of age in a predominantly black population
-
Cummings DM, Amadio Jr P, Taylor Jr EJ, et al. The antihyper-tensive response to lisinopril: the effect of age in a predominantly black population. J Clin Pharmacol 1989; 29: 25-32
-
(1989)
J Clin Pharmacol
, vol.29
, pp. 25-32
-
-
Cummings, D.M.1
Amadio Jr., P.2
Taylor Jr., E.J.3
-
142
-
-
0026334257
-
Antihyperten-sive efficacy, tolerance, and safety of ramipril in young vs old patients: A retrospective study
-
Saalbach R, Wochnik G, Mauersberger H, et al. Antihyperten-sive efficacy, tolerance, and safety of ramipril in young vs old patients: a retrospective study. J Cardiovasc Pharmacol 1991; 18 Suppl. 2: S134-6
-
(1991)
J Cardiovasc Pharmacol
, vol.18
, Issue.2 SUPPL.
-
-
Saalbach, R.1
Wochnik, G.2
Mauersberger, H.3
-
143
-
-
7644225896
-
Provision of cardiovascular protection by ACE inhibitors: A review of recent trials
-
Bertrand ME. Provision of cardiovascular protection by ACE inhibitors: a review of recent trials. Curr Med Res Opin 2004; 20: 1559-69
-
(2004)
Curr Med Res Opin
, vol.20
, pp. 1559-1569
-
-
Bertrand, M.E.1
-
144
-
-
0026502016
-
Regression of left ventricular hypertrophy: A meta-analysis
-
Dahlof B, Pennert K, Hansson L. Regression of left ventricular hypertrophy: a meta-analysis. Clin Exp Hypertens A 1992; 14: 173-80
-
(1992)
Clin Exp Hypertens A
, vol.14
, pp. 173-180
-
-
Dahlof, B.1
Pennert, K.2
Hansson, L.3
-
145
-
-
0028955321
-
Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure
-
Collaborative Group on ACE Inhibitor Trials
-
Garg R, Yusuf S. Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. Collaborative Group on ACE Inhibitor Trials. JAMA 1995; 273: 1450-6
-
(1995)
JAMA
, vol.273
, pp. 1450-1456
-
-
Garg, R.1
Yusuf, S.2
-
146
-
-
0034688194
-
Effects of an angiotensinconverting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients: The Heart Outcomes Prevention Evaluation Study Investigators
-
Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensinconverting- enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients: the Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 145-53
-
(2000)
N Engl J Med
, vol.342
, pp. 145-153
-
-
Yusuf, S.1
Sleight, P.2
Pogue, J.3
-
147
-
-
0042330455
-
Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: Randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study)
-
Fox KM. Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003; 362: 782-8
-
(2003)
Lancet
, vol.362
, pp. 782-788
-
-
Fox, K.M.1
-
148
-
-
0037434556
-
A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly
-
Wing LM, Reid CM, Ryan P, et al. A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly. N Engl J Med 2003; 348: 583-92
-
(2003)
N Engl J Med
, vol.348
, pp. 583-592
-
-
Wing, L.M.1
Reid, C.M.2
Ryan, P.3
-
149
-
-
0027158505
-
Blood pressure response to the first dose of angiotensin-converting enzyme inhibitors in congestive heart failure
-
Reid JL, Macfadyen RJ, Squire IB, et al. Blood pressure response to the first dose of angiotensin-converting enzyme inhibitors in congestive heart failure. Am J Cardiol 1993; 71: 57E-60E
-
(1993)
Am J Cardiol
, vol.71
-
-
Reid, J.L.1
Macfadyen, R.J.2
Squire, I.B.3
-
150
-
-
0036069796
-
Use of angiotensin-converting enzyme inhibitors in patients with heart failure and renal insufficiency: How concerned should we be by the rise in serum creatinine?
-
Ahmed A. Use of angiotensin-converting enzyme inhibitors in patients with heart failure and renal insufficiency: how concerned should we be by the rise in serum creatinine? J Am Geriatr Soc 2002; 50: 1297-300
-
(2002)
J Am Geriatr Soc
, vol.50
, pp. 1297-1300
-
-
Ahmed, A.1
-
151
-
-
13444263481
-
Drug combinations and impaired renal function: The 'triple whammy'
-
Loboz KK, Shenfield GM. Drug combinations and impaired renal function: the 'triple whammy'. Br J Clin Pharmacol 2005; 59: 239-43
-
(2005)
Br J Clin Pharmacol
, vol.59
, pp. 239-243
-
-
Loboz, K.K.1
Shenfield, G.M.2
-
152
-
-
0036682696
-
Using ACE inhibitors appropriately
-
Bicket DP. Using ACE inhibitors appropriately. Am Fam Physician 2002; 66: 461-8
-
(2002)
Am Fam Physician
, vol.66
, pp. 461-468
-
-
Bicket, D.P.1
-
153
-
-
0033534085
-
Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure: ATLAS Study Group
-
Packer M, Poole-Wilson PA, et al. Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure: ATLAS Study Group. Circulation 1999; 100: 2312-8
-
(1999)
Circulation
, vol.100
, pp. 2312-2318
-
-
Packer, M.1
Poole-Wilson, P.A.2
-
154
-
-
0035931330
-
Toleration of high doses of angiotensin-converting enzyme inhibitors in patients with chronic heart failure: Results from the ATLAS trial. The Assessment of Treatment with Lisinopril and Survival
-
Massie BM, Armstrong PW, Cleland JG, et al. Toleration of high doses of angiotensin-converting enzyme inhibitors in patients with chronic heart failure: results from the ATLAS trial. The Assessment of Treatment with Lisinopril and Survival. Arch Intern Med 2001; 161: 165-71
-
(2001)
Arch Intern Med
, vol.161
, pp. 165-171
-
-
Massie, B.M.1
Armstrong, P.W.2
Cleland, J.G.3
-
155
-
-
0346730900
-
Determinants of failure to prescribe target doses of angiotensin- converting enzyme inhibitors for heart failure
-
Manyemba J, Mangoni AA, Pettingale KW, et al. Determinants of failure to prescribe target doses of angiotensin-converting enzyme inhibitors for heart failure. Eur J Heart Fail 2003; 5: 693-6
-
(2003)
Eur J Heart Fail
, vol.5
, pp. 693-696
-
-
Manyemba, J.1
Mangoni, A.A.2
Pettingale, K.W.3
-
156
-
-
0031668830
-
Effect of age and gender on the pharmacokinetics of eprosartan
-
Tenero DM, Martin DE, Miller AK, et al. Effect of age and gender on the pharmacokinetics of eprosartan. Br J Clin Pharmacol 1998; 46: 267-70
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 267-270
-
-
Tenero, D.M.1
Martin, D.E.2
Miller, A.K.3
-
157
-
-
0031751158
-
The effects of age and gender on the pharmacokinetics of irbesartan
-
Vachharajani NN, Shyu WC, Smith RA, et al. The effects of age and gender on the pharmacokinetics of irbesartan. Br J Clin Pharmacol 1998; 46: 611-3
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 611-613
-
-
Vachharajani, N.N.1
Shyu, W.C.2
Smith, R.A.3
-
159
-
-
0031980805
-
The effect of age on the pharmacokinetics of valsartan
-
Sioufi A, Marfil F, Jaouen A, et al. The effect of age on the pharmacokinetics of valsartan. Biopharm Drug Dispos 1998; 19: 237-44
-
(1998)
Biopharm Drug Dispos
, vol.19
, pp. 237-244
-
-
Sioufi, A.1
Marfil, F.2
Jaouen, A.3
-
161
-
-
0035852724
-
Angiotensin II type 1 receptor blockers
-
Burnier M. Angiotensin II type 1 receptor blockers. Circulation 2001; 103: 904-12
-
(2001)
Circulation
, vol.103
, pp. 904-912
-
-
Burnier, M.1
-
162
-
-
0034612118
-
Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: Randomised trial: The Losartan Heart Failure Survival Study ELITE II
-
Pitt B, Poole-Wilson PA, Segal R, et al. Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial: the Losartan Heart Failure Survival Study ELITE II. Lancet 2000; 355: 1582-7
-
(2000)
Lancet
, vol.355
, pp. 1582-1587
-
-
Pitt, B.1
Poole-Wilson, P.A.2
Segal, R.3
-
163
-
-
7444237666
-
Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabe-tes and nephropathy
-
Barnett AH, Bain SC, Bouter P, et al. Angiotensin-receptor blockade versus converting-enzyme inhibition in type 2 diabe-tes and nephropathy. N Engl J Med 2004; 351: 1952-61
-
(2004)
N Engl J Med
, vol.351
, pp. 1952-1961
-
-
Barnett, A.H.1
Bain, S.C.2
Bouter, P.3
-
164
-
-
7244227872
-
Meta-analysis: Angiotensin-receptor blockers in chronic heart failure and high-risk acute myocardial infarction
-
Lee VC, Rhew DC, Dylan M, et al. Meta-analysis: angiotensin-receptor blockers in chronic heart failure and high-risk acute myocardial infarction. Ann Intern Med 2004; 141: 693-704
-
(2004)
Ann Intern Med
, vol.141
, pp. 693-704
-
-
Lee, V.C.1
Rhew, D.C.2
Dylan, M.3
-
165
-
-
0035818884
-
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
-
Cohn JN, Tognoni G. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 2001; 345: 1667-75
-
(2001)
N Engl J Med
, vol.345
, pp. 1667-1675
-
-
Cohn, J.N.1
Tognoni, G.2
-
166
-
-
10644255525
-
Morbidity, mortality, physiologic and functional parameters in elderly and non-elderly patients in the Valsartan Heart Failure Trial (ValHeFT)
-
Baruch L, Glazer RD, Aknay N, et al. Morbidity, mortality, physiologic and functional parameters in elderly and non-elderly patients in the Valsartan Heart Failure Trial (ValHeFT). Am Heart J 2004; 148: 951-7
-
(2004)
Am Heart J
, vol.148
, pp. 951-957
-
-
Baruch, L.1
Glazer, R.D.2
Aknay, N.3
-
167
-
-
0041408235
-
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
-
McMurray JJ, Ostergren J, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet 2003; 362: 767-71
-
(2003)
Lancet
, vol.362
, pp. 767-771
-
-
McMurray, J.J.1
Ostergren, J.2
Swedberg, K.3
-
168
-
-
0041909380
-
Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: The CHARM-Alternative trial
-
Granger CB, McMurray JJ, Yusuf S, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial. Lancet 2003; 362: 772-6
-
(2003)
Lancet
, vol.362
, pp. 772-776
-
-
Granger, C.B.1
McMurray, J.J.2
Yusuf, S.3
-
169
-
-
0041408234
-
Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: The CHARM-Preserved Trial
-
Yusuf S, Pfeffer MA, Swedberg K, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet 2003; 362: 777-81
-
(2003)
Lancet
, vol.362
, pp. 777-781
-
-
Yusuf, S.1
Pfeffer, M.A.2
Swedberg, K.3
-
170
-
-
0042410539
-
Effects of candesartan on mortality and morbidity in patients with chronic heart failure: The CHARM-Overall programme
-
Pfeffer MA, Swedberg K, Granger CB, et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet 2003; 362: 759-66
-
(2003)
Lancet
, vol.362
, pp. 759-766
-
-
Pfeffer, M.A.1
Swedberg, K.2
Granger, C.B.3
-
171
-
-
0037036971
-
Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: The OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan
-
Dickstein K, Kjekshus J. Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan. Lancet 2002; 360: 752-60
-
(2002)
Lancet
, vol.360
, pp. 752-760
-
-
Dickstein, K.1
Kjekshus, J.2
-
172
-
-
0037160968
-
Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
-
Dahlof B, Devereux RB, Kjeldsen SE, et al. Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002; 359: 995-1003
-
(2002)
Lancet
, vol.359
, pp. 995-1003
-
-
Dahlof, B.1
Devereux, R.B.2
Kjeldsen, S.E.3
-
173
-
-
7644236592
-
Atenolol in hyperten-sion: Is it a wise choice?
-
Carlberg B, Samuelsson O, Lindholm LH. Atenolol in hyperten-sion: is it a wise choice? Lancet 2004; 364: 1684-9
-
(2004)
Lancet
, vol.364
, pp. 1684-1689
-
-
Carlberg, B.1
Samuelsson, O.2
Lindholm, L.H.3
-
174
-
-
0037534905
-
The Study on Cognition and Prognosis in the Elderly (SCOPE): Principal results of a randomized double-blind intervention trial
-
Lithell H, Hansson L, Skoog I, et al. The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens 2003; 21: 875-86
-
(2003)
J Hypertens
, vol.21
, pp. 875-886
-
-
Lithell, H.1
Hansson, L.2
Skoog, I.3
-
175
-
-
0036615537
-
The practical aspects of combination therapy with angiotensin receptor blockers and angiotensin-converting enzyme inhibitors
-
Sica DA. The practical aspects of combination therapy with angiotensin receptor blockers and angiotensin-converting enzyme inhibitors. J Renin Angiotensin Aldosterone Syst 2002; 3: 66-71
-
(2002)
J Renin Angiotensin Aldosterone Syst
, vol.3
, pp. 66-71
-
-
Sica, D.A.1
-
176
-
-
16644378834
-
Beneficial impact on cardiovascular risk factors by dual blockade of the renin-angiotensin system in diabetic nephropathy
-
Jacobsen P, Parving HH. Beneficial impact on cardiovascular risk factors by dual blockade of the renin-angiotensin system in diabetic nephropathy. Kidney Int Suppl 2004; 92: S108-10
-
(2004)
Kidney Int Suppl
, vol.92
-
-
Jacobsen, P.1
Parving, H.H.2
-
177
-
-
18244406792
-
Systematic review of combined angiotensin-converting enzyme inhibition and angiotensin receptor blockade in hypertension
-
Doulton TW, He FJ, MacGregor GA. Systematic review of combined angiotensin-converting enzyme inhibition and angiotensin receptor blockade in hypertension. Hypertension 2005; 45: 880-6
-
(2005)
Hypertension
, vol.45
, pp. 880-886
-
-
Doulton, T.W.1
He, F.J.2
MacGregor, G.A.3
-
178
-
-
0242490542
-
Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
-
Pfeffer MA, McMurray JJ, Velazquez EJ, et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003; 349: 1893-906
-
(2003)
N Engl J Med
, vol.349
, pp. 1893-1906
-
-
Pfeffer, M.A.1
McMurray, J.J.2
Velazquez, E.J.3
-
179
-
-
0024270530
-
Disopyramide pharmacokinetics in the elderly after single oral administration
-
Roberto P, Vitaliano B, Donatella P, et al. Disopyramide pharmacokinetics in the elderly after single oral administration. Pharmacol Res Commun 1988; 20: 1025- 34
-
(1988)
Pharmacol Res Commun
, vol.20
, pp. 1025-1034
-
-
Roberto, P.1
Vitaliano, B.2
Donatella, P.3
-
180
-
-
0022398628
-
The influence of age and smoking on the elimination of disopyramide
-
Bonde J, Pedersen LE, Bodtker S, et al. The influence of age and smoking on the elimination of disopyramide. Br J Clin Pharmacol 1985; 20: 453-8
-
(1985)
Br J Clin Pharmacol
, vol.20
, pp. 453-458
-
-
Bonde, J.1
Pedersen, L.E.2
Bodtker, S.3
-
181
-
-
0018890805
-
Pharmacokinetics of lignocaine in the elderly [proceedings]
-
Cusack B, Kelly JG, Lavan J, et al. Pharmacokinetics of lignocaine in the elderly [proceedings]. Br J Clin Pharmacol 1980; 9: 293P-4P
-
(1980)
Br J Clin Pharmacol
, vol.9
-
-
Cusack, B.1
Kelly, J.G.2
Lavan, J.3
-
182
-
-
0018145266
-
Reduced quinidine clearance in elderly persons
-
Ochs HR, Greenblatt DJ, Woo E, et al. Reduced quinidine clearance in elderly persons. Am J Cardiol 1978; 42: 481-5
-
(1978)
Am J Cardiol
, vol.42
, pp. 481-485
-
-
Ochs, H.R.1
Greenblatt, D.J.2
Woo, E.3
-
183
-
-
0017713105
-
Lignocaine kinetics in cardiac patients and aged subjects
-
Nation RL, Triggs EJ, Selig M. Lignocaine kinetics in cardiac patients and aged subjects. Br J Clin Pharmacol 1977; 4: 439-48
-
(1977)
Br J Clin Pharmacol
, vol.4
, pp. 439-448
-
-
Nation, R.L.1
Triggs, E.J.2
Selig, M.3
-
186
-
-
0030972647
-
Effects of age on cardiovascular re-sponses to adrenaline in man
-
White M, Leenen FH. Effects of age on cardiovascular re-sponses to adrenaline in man. Br J Clin Pharmacol 1997; 43: 407-14
-
(1997)
Br J Clin Pharmacol
, vol.43
, pp. 407-414
-
-
White, M.1
Leenen, F.H.2
-
187
-
-
0025345231
-
Effect of intravenous atropine on gastric emptying, paracetamol absorption, salivary flow and heart rate in young and fit elderly volunteers
-
Rashid MU, Bateman DN. Effect of intravenous atropine on gastric emptying, paracetamol absorption, salivary flow and heart rate in young and fit elderly volunteers. Br J Clin Pharmacol 1990; 30: 25-34
-
(1990)
Br J Clin Pharmacol
, vol.30
, pp. 25-34
-
-
Rashid, M.U.1
Bateman, D.N.2
-
188
-
-
0019723465
-
Age-related decrease in cardiac and peripheral vascular responsiveness to isoprenaline: Studies in normal subjects
-
Lond
-
van Brummelen P, Buhler FR, Kiowski W, et al. Age-related decrease in cardiac and peripheral vascular responsiveness to isoprenaline: studies in normal subjects. Clin Sci (Lond) 1981; 60: 571-7
-
(1981)
Clin Sci
, vol.60
, pp. 571-577
-
-
Van Brummelen, P.1
Buhler, F.R.2
Kiowski, W.3
-
189
-
-
0031819539
-
Age, hypertension, and cardiac responses to beta-agonist in humans
-
White M, Fourney A, Leenen FH. Age, hypertension, and cardiac responses to beta-agonist in humans. Clin Pharmacol Ther 1998; 63: 663-71
-
(1998)
Clin Pharmacol Ther
, vol.63
, pp. 663-671
-
-
White, M.1
Fourney, A.2
Leenen, F.H.3
-
190
-
-
0024261694
-
Age does not alter human vascular and nonvascular beta 2-adrenergic responses to isoproterenol
-
Klein C, Hiatt WR, Gerber JG, et al. Age does not alter human vascular and nonvascular beta 2-adrenergic responses to isoproterenol. Clin Pharmacol Ther 1988; 44: 573-8
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 573-578
-
-
Klein, C.1
Hiatt, W.R.2
Gerber, J.G.3
-
191
-
-
0346496571
-
National trends in antiarrhythmic and antithrombotic medication use in atrial fibrillation
-
Fang MC, Stafford RS, Ruskin JN, et al. National trends in antiarrhythmic and antithrombotic medication use in atrial fibrillation. Arch Intern Med 2004; 164: 55-60
-
(2004)
Arch Intern Med
, vol.164
, pp. 55-60
-
-
Fang, M.C.1
Stafford, R.S.2
Ruskin, J.N.3
-
192
-
-
4444317098
-
Cardiac arrhythmias: The quest for a cure: A histori-cal perspective
-
Wellens HJ. Cardiac arrhythmias: the quest for a cure: a histori-cal perspective. J Am Coll Cardiol 2004; 44: 1155-63
-
(2004)
J Am Coll Cardiol
, vol.44
, pp. 1155-1163
-
-
Wellens, H.J.1
-
193
-
-
5344244027
-
Time trends in the use of beta-blockers and other pharmacotherapies in older adults with congestive heart failure
-
Smith NL, Chan JD, Rea TD, et al. Time trends in the use of beta-blockers
-
(2004)
Am Heart J
, vol.148
, pp. 710-717
-
-
Smith, N.L.1
Chan, J.D.2
Rea, T.D.3
-
194
-
-
0037453950
-
Association of serum digoxin concentration and outcomes in patients with heart failure
-
Rathore SS, Curtis JP, Wang Y, et al. Association of serum digoxin concentration and outcomes in patients with heart failure. JAMA 2003; 289: 871-8
-
(2003)
JAMA
, vol.289
, pp. 871-878
-
-
Rathore, S.S.1
Curtis, J.P.2
Wang, Y.3
-
195
-
-
0036786383
-
No effect of age or gender on the pharmacokinetics of rosuvastatin: A new HMG-CoA reductase inhibitor
-
Martin PD, Dane AL, Nwose OM, et al. No effect of age or gender on the pharmacokinetics of rosuvastatin: a new HMG-CoA reductase inhibitor. J Clin Pharmacol 2002; 42: 1116-21
-
(2002)
J Clin Pharmacol
, vol.42
, pp. 1116-1121
-
-
Martin, P.D.1
Dane, A.L.2
Nwose, O.M.3
-
196
-
-
0030005053
-
Effect of age and gender on pharmacokinetics of atorvastatin in humans
-
Gibson DM, Bron NJ, Richens A, et al. Effect of age and gender on pharmacokinetics of atorvastatin in humans. J Clin Pharmacol 1996; 36: 242-6
-
(1996)
J Clin Pharmacol
, vol.36
, pp. 242-246
-
-
Gibson, D.M.1
Bron, N.J.2
Richens, A.3
-
197
-
-
0026591839
-
Influence of age and gender on the plasma profiles of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitory activity following multiple doses of lovastatin and simvastatin
-
Cheng H, Rogers JD, Sweany AE, et al. Influence of age and gender on the plasma profiles of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitory activity following multiple doses of lovastatin and simvastatin. Pharm Res 1992; 9: 1629-33
-
(1992)
Pharm Res
, vol.9
, pp. 1629-1633
-
-
Cheng, H.1
Rogers, J.D.2
Sweany, A.E.3
-
198
-
-
0344653659
-
Cholesterol-lowering therapy in women and elderly patients with myocardial infarction or angina pectoris: Findings from the Scandinavian Simvastatin Survival Study (4S)
-
Miettinen TA, Pyorala K, Olsson AG, et al. Cholesterol-lower-ing therapy in women and elderly patients with myocardial infarction or angina pectoris: findings from the Scandinavian Simvastatin Survival Study (4S). Circulation 1997; 96: 4211-8
-
(1997)
Circulation
, vol.96
, pp. 4211-4218
-
-
Miettinen, T.A.1
Pyorala, K.2
Olsson, A.G.3
-
199
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383-9
-
(1994)
Lancet
, vol.344
, pp. 1383-1389
-
-
-
200
-
-
0342981862
-
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
-
Cholesterol and Recurrent Events Trial Investigators
-
Sacks FM, Pfeffer MA, Moye LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial Investigators. N Engl J Med 1996; 335: 1001-9
-
(1996)
N Engl J Med
, vol.335
, pp. 1001-1009
-
-
Sacks, F.M.1
Pfeffer, M.A.2
Moye, L.A.3
-
201
-
-
0032487931
-
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels: The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
-
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels: the Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. N Engl J Med 1998; 339: 1349-57
-
(1998)
N Engl J Med
, vol.339
, pp. 1349-1357
-
-
-
202
-
-
0037031061
-
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised pla-cebo-controlled trial
-
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised pla-cebo-controlled trial. Lancet 2002; 360: 7-22
-
(2002)
Lancet
, vol.360
, pp. 7-22
-
-
-
203
-
-
0037164314
-
Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomised controlled trial
-
Shepherd J, Blauw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet 2002; 360: 1623-30
-
(2002)
Lancet
, vol.360
, pp. 1623-1630
-
-
Shepherd, J.1
Blauw, G.J.2
Murphy, M.B.3
-
204
-
-
0020517365
-
Pharmacokinetics of aspirin and salicylate in elderly subjects and in patients with alcoholic liver disease
-
Roberts MS, Rumble RH, Wanwimolruk S, et al. Pharmacokinetics of aspirin and salicylate in elderly subjects and in patients with alcoholic liver disease. Eur J Clin Pharmacol 1983; 25: 253-61
-
(1983)
Eur J Clin Pharmacol
, vol.25
, pp. 253-261
-
-
Roberts, M.S.1
Rumble, R.H.2
Wanwimolruk, S.3
-
205
-
-
0022222072
-
The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites
-
Ho PC, Triggs EJ, Bourne DW, et al. The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites. Br J Clin Pharmacol 1985; 19: 675-84
-
(1985)
Br J Clin Pharmacol
, vol.19
, pp. 675-684
-
-
Ho, P.C.1
Triggs, E.J.2
Bourne, D.W.3
-
206
-
-
0018304843
-
Pharmacokinetics of salicy-lates in elderly
-
Cuny G, Royer RJ, Mur JM, et al. Pharmacokinetics of salicy-lates in elderly. Gerontology 1979; 25: 49-55
-
(1979)
Gerontology
, vol.25
, pp. 49-55
-
-
Cuny, G.1
Royer, R.J.2
Mur, J.M.3
-
207
-
-
0032801029
-
Clopidogrel antiplatelet activity is independent of age and presence of atherosclerosis
-
Denninger MH, Necciari J, Serre-Lacroix E, et al. Clopidogrel antiplatelet activity is independent of age and presence of atherosclerosis. Semin Thromb Hemost 1999; 25 Suppl. 2: 41-5
-
(1999)
Semin Thromb Hemost
, vol.25
, Issue.2 SUPPL.
, pp. 41-45
-
-
Denninger, M.H.1
Necciari, J.2
Serre-Lacroix, E.3
-
208
-
-
0025748018
-
Single and multiple dose pharmacokinetics of ticlopidine in young and elderly subjects
-
Shah J, Teitelbaum P, Molony B, et al. Single and multiple dose pharmacokinetics of ticlopidine in young and elderly subjects. Br J Clin Pharmacol 1991; 32: 761-4
-
(1991)
Br J Clin Pharmacol
, vol.32
, pp. 761-764
-
-
Shah, J.1
Teitelbaum, P.2
Molony, B.3
-
210
-
-
0034809384
-
Population pharmacody namics in patients receiving tinzaparin for the prevention and treatment of deep vein thrombosis
-
Barrett JS, Gibiansky E, Hull RD, et al. Population pharmacody namics in patients receiving tinzaparin for the prevention and treatment of deep vein thrombosis. Int J Clin Pharmacol Ther 2001; 39: 431-46
-
(2001)
Int J Clin Pharmacol Ther
, vol.39
, pp. 431-446
-
-
Barrett, J.S.1
Gibiansky, E.2
Hull, R.D.3
-
211
-
-
0033663570
-
Pharmacokinetics and pharmacodynamics of tenecteplase: Results from a phase II study in patients with acute myocardial infarction
-
Modi NB, Fox NL, Clow FW, et al. Pharmacokinetics and pharmacodynamics of tenecteplase: results from a phase II study in patients with acute myocardial infarction. J Clin Pharmacol 2000; 40: 508-15
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 508-515
-
-
Modi, N.B.1
Fox, N.L.2
Clow, F.W.3
-
212
-
-
0033710044
-
Elderly patients treated with tinzaparin (Innohep) administered once daily (175 anti-Xa IU/kg): Anti-Xa and anti-IIa activities over 10 days
-
Siguret V, Pautas E, Fevrier M, et al. Elderly patients treated with tinzaparin (Innohep) administered once daily (175 anti-Xa IU/kg): anti-Xa and anti-IIa activities over 10 days. Thromb Haemost 2000; 84: 800-4
-
(2000)
Thromb Haemost
, vol.84
, pp. 800-804
-
-
Siguret, V.1
Pautas, E.2
Fevrier, M.3
-
213
-
-
17644444813
-
Risk of uncomplicated peptic ulcer among users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs
-
Garcia Rodriguez LA, Hernandez-Diaz S. Risk of uncomplicated peptic ulcer among users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs. Am J Epidemiol 2004; 159: 23-31
-
(2004)
Am J Epidemiol
, vol.159
, pp. 23-31
-
-
Garcia Rodriguez, L.A.1
Hernandez-Diaz, S.2
-
215
-
-
10644264553
-
Proton-pump inhibitors reduce the risk of uncomplicated peptic ulcer in elderly either acute or chronic users of aspirin/non-steroidal anti-inflammatory drugs
-
Pilotto A, Franceschi M, Leandro G, et al. Proton-pump inhibitors reduce the risk of uncomplicated peptic ulcer in elderly either acute or chronic users of aspirin/non-steroidal anti-inflammatory drugs. Aliment Pharmacol Ther 2004; 20: 1091-7
-
(2004)
Aliment Pharmacol Ther
, vol.20
, pp. 1091-1097
-
-
Pilotto, A.1
Franceschi, M.2
Leandro, G.3
-
216
-
-
0035908781
-
Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in pa-tients undergoing percutaneous coronary intervention: The PCI-CURE study
-
Mehta SR, Yusuf S, Peters RJ, et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in pa-tients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet 2001; 358: 527-33
-
(2001)
Lancet
, vol.358
, pp. 527-533
-
-
Mehta, S.R.1
Yusuf, S.2
Peters, R.J.3
-
217
-
-
0035899289
-
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
-
Yusuf S, Zhao F, Mehta SR, et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001; 345: 494-502
-
(2001)
N Engl J Med
, vol.345
, pp. 494-502
-
-
Yusuf, S.1
Zhao, F.2
Mehta, S.R.3
-
218
-
-
20144373281
-
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
-
Sabatine MS, Cannon CP, Gibson CM, et al. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 2005; 352: 1179-89
-
(2005)
N Engl J Med
, vol.352
, pp. 1179-1189
-
-
Sabatine, M.S.1
Cannon, C.P.2
Gibson, C.M.3
-
219
-
-
13244287863
-
Low-molecular-weight heparin for the treatment of venous thromboembolism in the elderly
-
Pineo GF, Hull RD. Low-molecular-weight heparin for the treatment of venous thromboembolism in the elderly. Clin Appl Thromb Hemost 2005; 11: 15-23
-
(2005)
Clin Appl Thromb Hemost
, vol.11
, pp. 15-23
-
-
Pineo, G.F.1
Hull, R.D.2
-
220
-
-
0041473374
-
The present and future of heparin, low molecular weight heparins, pentasaccharide, and hirudin for venous thromboembolism and acute coronary syndromes
-
Haas S. The present and future of heparin, low molecular weight heparins, pentasaccharide, and hirudin for venous thromboembolism and acute coronary syndromes. Semin Vasc Med 2003; 3: 139-46
-
(2003)
Semin Vasc Med
, vol.3
, pp. 139-146
-
-
Haas, S.1
-
221
-
-
2942654843
-
Role of thrombotic and fibrinolytic factors in acute coronary syndromes
-
Saigo M, Hsue PY, Waters DD. Role of thrombotic and fibrinolytic factors in acute coronary syndromes. Prog Cardiovasc Dis 2004; 46: 524-38
-
(2004)
Prog Cardiovasc Dis
, vol.46
, pp. 524-538
-
-
Saigo, M.1
Hsue, P.Y.2
Waters, D.D.3
-
222
-
-
0034075365
-
Warfarin for stroke prevention still underused in atrial fibrillation: Patterns of omission
-
Cohen N, Almoznino-Sarafian D, Alon I, et al. Warfarin for stroke prevention still underused in atrial fibrillation: patterns of omission. Stroke 2000; 31: 1217-22
-
(2000)
Stroke
, vol.31
, pp. 1217-1222
-
-
Cohen, N.1
Almoznino-Sarafian, D.2
Alon, I.3
-
223
-
-
0034814620
-
ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: Executive summary
-
A Report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation): developed in collaboration with the North American Society of Pacing and Electrophysiology
-
Fuster V, Ryden LE, Asinger RW, et al. ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation: executive summary. A Report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines and Policy Conferences (Committee to Develop Guidelines for the Management of Patients With Atrial Fibrillation): developed in collaboration with the North American Society of Pacing and Electrophysiology. J Am Coll Cardiol 2001; 38: 1231-66
-
(2001)
J Am Coll Cardiol
, vol.38
, pp. 1231-1266
-
-
Fuster, V.1
Ryden, L.E.2
Asinger, R.W.3
-
224
-
-
28544451993
-
-
Canberra (ACT): Australian Institute of Health and Welfare
-
Australian Institute of Health and Welfare (AIHW). Australian Population Patterns and Implications: AIHW Cat. No. DIS-19. Canberra (ACT): Australian Institute of Health and Welfare, 2000: 1-7
-
(2000)
Australian Population Patterns and Implications: AIHW Cat. No. DIS-19
, pp. 1-7
-
-
|