Renal handling of drugs in the healthy elderly: Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged

European Journal of Clinical Pharmacology

Volumn 55, Issue 3, 1999, Pages 205-211

  Fliser, D ^b   Bischoff, I ^a   Hanses, A ^a   Block, S ^b   Joest, M ^b   Ritz, E ^b   Mutschler, E ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Elderly; Pharmacokinetics; Renal function

Indexed keywords

4 AMINOHIPPURIC ACID; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CREATININE; DIURETIC AGENT; HYDROCHLOROTHIAZIDE PLUS TRIAMTERENE; INULIN; NOOTROPIC AGENT; PIRACETAM;

ADULT; AGED; AGING; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE CLEARANCE; DOSE RESPONSE; DRUG CLEARANCE; DRUG EXCRETION; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADRENERGIC BETA-ANTAGONISTS; ADULT; AGED; AGING; ATENOLOL; CREATININE; DIURETICS; FEMALE; GLOMERULAR FILTRATION RATE; HEMODYNAMIC PROCESSES; HUMANS; HYDROCHLOROTHIAZIDE; KIDNEY; KIDNEY FUNCTION TESTS; MALE; NOOTROPIC AGENTS; PHARMACOKINETICS; PIRACETAM; TRIAMTERENE;

EID: 0032986470     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050619     Document Type: Article

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