메뉴 건너뛰기




Volumn 76, Issue 2, 2005, Pages 129-134

Interactions of the integrin subunit β1A with protein kinase B/Akt, p130Cas and paxillin contribute to regulation of radiation survival

Author keywords

1 integrin; Ionizing radiation; p130Cas; Paxillin; PKB Akt

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTINEOPLASTIC AGENT; BETA INTEGRIN; BETA1A INTEGRIN; COLLAGEN TYPE 3; FIBRONECTIN; FOCAL ADHESION KINASE; IMMUNOGLOBULIN G; LAMININ; PAXILLIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; POLYLYSINE; PROTEIN KINASE B; PROTEIN P130; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VITRONECTIN; WORTMANNIN;

EID: 28444493595     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2005.06.018     Document Type: Conference Paper
Times cited : (25)

References (27)
  • 1
    • 0036363390 scopus 로고    scopus 로고
    • Splice variants of human beta 1 integrins: Origin, biosynthesis and functions
    • A. Armulik Splice variants of human beta 1 integrins: origin, biosynthesis and functions Front Biosci 7 2002 d219 d227
    • (2002) Front Biosci , vol.7
    • Armulik, A.1
  • 2
    • 0035872199 scopus 로고    scopus 로고
    • Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
    • J. Brognard, A.S. Clark, Y. Ni, and P.A. Dennis Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation Cancer Res 61 2001 3986 3997
    • (2001) Cancer Res , vol.61 , pp. 3986-3997
    • Brognard, J.1    Clark, A.S.2    Ni, Y.3    Dennis, P.A.4
  • 3
    • 0024150623 scopus 로고
    • Focal adhesions: Transmembrane junctions between the extracellular matrix and the cytoskeleton
    • K. Burridge, K. Fath, T. Kelly, G. Nuckolls, and C. Turner Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton Annu Rev Cell Biol 4 1988 487 525
    • (1988) Annu Rev Cell Biol , vol.4 , pp. 487-525
    • Burridge, K.1    Fath, K.2    Kelly, T.3    Nuckolls, G.4    Turner, C.5
  • 4
    • 3142554541 scopus 로고    scopus 로고
    • Fibronectin alters cell survival and intracellular signaling of confluent A549 cultures after irradiation
    • N. Cordes, and C. Beinke Fibronectin alters cell survival and intracellular signaling of confluent A549 cultures after irradiation Cancer Biol Ther 3 2004 47 53
    • (2004) Cancer Biol Ther , vol.3 , pp. 47-53
    • Cordes, N.1    Beinke, C.2
  • 6
    • 0038751716 scopus 로고    scopus 로고
    • Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro
    • N. Cordes, and D. van Beuningen Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro Brit J Cancer 88 2003 1470 1479
    • (2003) Brit J Cancer , vol.88 , pp. 1470-1479
    • Cordes, N.1    Van Beuningen, D.2
  • 7
    • 4143127943 scopus 로고    scopus 로고
    • Overexpression of hyperactive integrin-linked kinase leads to increased cellular radiosensitivity
    • N. Cordes Overexpression of hyperactive integrin-linked kinase leads to increased cellular radiosensitivity Cancer Res 64 2004 5683 5692
    • (2004) Cancer Res , vol.64 , pp. 5683-5692
    • Cordes, N.1
  • 9
    • 0037450655 scopus 로고    scopus 로고
    • A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control
    • R.D. Evans, V.C. Perkins, A. Henry, P.E. Stephens, M.K. Robinson, and F.M. Watt A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control J Cell Biol 160 2003 589 596
    • (2003) J Cell Biol , vol.160 , pp. 589-596
    • Evans, R.D.1    Perkins, V.C.2    Henry, A.3    Stephens, P.E.4    Robinson, M.K.5    Watt, F.M.6
  • 10
    • 0033944543 scopus 로고    scopus 로고
    • Differential role of β1C and β1A integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and ras/mitogen-activated protein kinase pathways
    • M. Fornaro, C.A. Steger, A.M. Bennett, J.J. Wu, and L.R. Languino Differential role of β1C and β1A integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and ras/mitogen- activated protein kinase pathways Mol Biol Cell 11 2000 2235 2249
    • (2000) Mol Biol Cell , vol.11 , pp. 2235-2249
    • Fornaro, M.1    Steger, C.A.2    Bennett, A.M.3    Wu, J.J.4    Languino, L.R.5
  • 11
  • 12
    • 0038281227 scopus 로고    scopus 로고
    • Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002
    • A.K. Gupta, G.J. Cerniglia, and R. Mick Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002 Int J Radiat Oncol Biol Phys 56 2003 846 853
    • (2003) Int J Radiat Oncol Biol Phys , Issue.56 , pp. 846-853
    • Gupta, A.K.1    Cerniglia, G.J.2    Mick, R.3
  • 13
    • 0030026679 scopus 로고    scopus 로고
    • Regulation of cell adhesion and anchorage-dependent growth by a new (1-integrin-linked protein kinase
    • G.E. Hannigan, C. Leung-Hagesteijn, and L. Fitz-Gibbon Regulation of cell adhesion and anchorage-dependent growth by a new (1-integrin-linked protein kinase Nature 379 1996 91 96
    • (1996) Nature , vol.379 , pp. 91-96
    • Hannigan, G.E.1    Leung-Hagesteijn, C.2    Fitz-Gibbon, L.3
  • 14
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • R.O. Hynes Integrins: Bidirectional, allosteric signaling machines Cell 110 2002 673 687
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 16
    • 0030913673 scopus 로고    scopus 로고
    • Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
    • A. Khwaja, P. Rodriguez-Viciana, S. Wennström, H.P. Warne, and J. Downward Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway EMBO J 16 1997 2783 2793
    • (1997) EMBO J , vol.16 , pp. 2783-2793
    • Khwaja, A.1    Rodriguez-Viciana, P.2    Wennström, S.3    Warne, H.P.4    Downward, J.5
  • 19
    • 0037509990 scopus 로고    scopus 로고
    • Focal adhesion kinase: The first ten years
    • J.T. Parsons Focal adhesion kinase: the first ten years J Cell Sci 116 2003 1409 1416
    • (2003) J Cell Sci , vol.116 , pp. 1409-1416
    • Parsons, J.T.1
  • 20
    • 0032513019 scopus 로고    scopus 로고
    • Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins
    • M. Pfaff, S. Liu, D.J. Erle, and M.H. Ginsberg Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins J Biol Chem 273 1998 6104 6109
    • (1998) J Biol Chem , vol.273 , pp. 6104-6109
    • Pfaff, M.1    Liu, S.2    Erle, D.J.3    Ginsberg, M.H.4
  • 21
    • 0035948579 scopus 로고    scopus 로고
    • Biochemical signals and biological responses elicited by the focal adhesion kinase
    • M.D. Schaller Biochemical signals and biological responses elicited by the focal adhesion kinase Biochem Biophys Acta 1540 2001 1 21
    • (2001) Biochem Biophys Acta , vol.1540 , pp. 1-21
    • Schaller, M.D.1
  • 22
    • 0033032317 scopus 로고    scopus 로고
    • Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
    • T. Sethi, R.C. Rintoul, and S.M. Moore Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo Nat Med 5 1999 662 668
    • (1999) Nat Med , vol.5 , pp. 662-668
    • Sethi, T.1    Rintoul, R.C.2    Moore, S.M.3
  • 23
    • 0032803067 scopus 로고    scopus 로고
    • Focal adhesion targeting: The critical determinant of FAK regulation and substrate phosphorylation
    • Y. Shen, and M.D. Schaller Focal adhesion targeting: the critical determinant of FAK regulation and substrate phosphorylation Mol Biol Cell 10 1999 2507 2518
    • (1999) Mol Biol Cell , vol.10 , pp. 2507-2518
    • Shen, Y.1    Schaller, M.D.2
  • 24
    • 0042165831 scopus 로고    scopus 로고
    • Alpha v integrin inhibitors and cancer therapy
    • G.C. Tucker Alpha v integrin inhibitors and cancer therapy Curr Opin Investig Drugs 4 2003 722 731
    • (2003) Curr Opin Investig Drugs , vol.4 , pp. 722-731
    • Tucker, G.C.1
  • 25
    • 3142587028 scopus 로고    scopus 로고
    • Tumor microenvironmental physiology and its implications for radiation oncology
    • P. Vaupel Tumor microenvironmental physiology and its implications for radiation oncology Semin Radiat Oncol 14 2004 198 206
    • (2004) Semin Radiat Oncol , vol.14 , pp. 198-206
    • Vaupel, P.1
  • 26
    • 11344254134 scopus 로고    scopus 로고
    • Beta1-Integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases
    • T. Velling, S. Nilsson, A. Stefansson, and S. Johansson beta1-Integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases EMBO Rep 5 2004 901 905
    • (2004) EMBO Rep , vol.5 , pp. 901-905
    • Velling, T.1    Nilsson, S.2    Stefansson, A.3    Johansson, S.4
  • 27
    • 0033942173 scopus 로고    scopus 로고
    • The cytoplasmic tyrosines of integrin subunit beta1 are involved in focal adhesion kinase activation
    • K. Wennerberg, A. Armulik, and T. Sakai The cytoplasmic tyrosines of integrin subunit beta1 are involved in focal adhesion kinase activation Mol Cell Biol 20 2000 5758 5765
    • (2000) Mol Cell Biol , vol.20 , pp. 5758-5765
    • Wennerberg, K.1    Armulik, A.2    Sakai, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.