Pathogenesis of herpes simplex hepatits in macrophage-depleted mice: Possible involvement of tumor necrosis factor-α and inducible nitric oxide synthase in massive apoptosis

Anatomical Science International

Volumn 80, Issue 4, 2005, Pages 199-211

  Irie, Hiroshi ^a   Shiga, Junji ^a  

^a TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; Herpes simplex virus; Inducible nitric oxide synthase; Macrophage blockage; Tumor necrosis factor

Indexed keywords

ALPHA INTERFERON; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FREE RADICAL; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE SYNTHASE; SILICON DIOXIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; HEPATITIS; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; IMMUNOHISTOCHEMISTRY; LIVER ADENOMA; LIVER CELL; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; STATISTICAL ANALYSIS; VIRUS INFECTION;

ANIMALS; APOPTOSIS; DNA PRIMERS; E-SELECTIN; HEPATITIS, VIRAL, ANIMAL; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INTERFERON-ALPHA; INTERLEUKIN-6; LIVER; MACROPHAGES; MICE; MICE, INBRED C3H; NITRIC OXIDE SYNTHASE TYPE II; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SILICON DIOXIDE; SIMPLEXVIRUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 28444432627     PISSN: 14476959     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Adler H, Beland JL, Del-Pan NC et al. (1997) Suppression of herpes simplex virus type 1 (HSV-l)-induced pneumonia in mice by inhibition of inducible nitric oxide synthase (iNOS, NOS2). J Exp Med 9, 1533-40.
2. Akaike T, Maeda H (2000) Nitric oxide and virus infection. Immunology 101, 300-8.
3. Akaike T, Weihe E, Schaefer M et al. (1995) Effect of neurotropic virus infection on neuronal and inducible nitric oxide synthase activity in rat brain. J Neurovirol 1, 118-25.
4. Akaike T, Noguchi Y, Ijirii S et al. (1996) Pathogenesis of influenza virus-induced pneumonia: Involvement of both nitric oxide and oxygen radicals. Proc Natl Acad Sci USA 93, 2448-53.
5. Akaike T, Suga M, Maeda H (1998) Free radicals in viral pathogenesis: Molecular mechanisms involving Superoxide and NO. Proc Soc Exp Biol Med 217, 64-73.
6. Alonso S, Minty A, Bourlet Y, Buckinghamm M (1986) Comparison of three actin-coding sequences in the mouse: Evolutionary relationships between the actin genes of warm-blooded vertebrates. J Mol Evol 23, 11-22.
7. Ando K, Moriyama T, Guidotti LG et al. (1993) Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J Exp Med 178, 1551-4.
8. Beckman J, Koppenol WH (1996) Nitric oxide, Superoxide, and peroxynitrite: The good, the bad, and the ugly. Am J Physiol 271, C1424-C1437.
9. Bergmyer HU (1984) Enzymes: Transferases. In: Methods of Enzyme Analysis, 3rd edn (Bergmyer HU, ed.). Verlag Chemie, Weinheim, 416-57.
10. Bi Z, Barna M, Komatsu T, Reiss CS (1995) Vesicular stomatitis virus infection of the central nervous system activates both innate and acquired immunity. J Virol 69, 6466-72.
11. Bonder CS, Ajuebor MN, Zbytnuik LD, Kubes P, Swain MG (2004) Essential role for neutrophil ecuitment to the liver in concanavalin A-induced hepatitis. J immunol 172, 24-53.
12. Carninci P, Nishiyama Y, Westover A et al. (1998) Thermostabilization and thermoactivation of thermolabile enzymes by trehalose and its application for the synthesis of full length cDNA. Proc Natl Acad Sci USA 95, 520-4.
13. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidium thiocyonate-phenol-chloroform extraction. Anal Biochem 162, 156-9.
14. Chosay JG, Essani NA, Dunn CJ, Jaeschke H (1997) Neutrophil margination and extravasation in sinusoids and venules of liver during endotoxin-induced injury. Am J Physiol 272, G1195-G1200.
15. Curran RD, Billiar TR, Stuehr DJ et al. (1990) Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis. Ann Surg 212, 462-71.
16. Curran RD, Billiar TR, Stuehr DJ, Hofmann K, Simmons RL (1989) Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells. J Exp Med 170, 1769-74.
17. de la Mata M, Meager A, Rolando N et al. (1990) Tumor necrosis factor production in fulminant hepatic failure: Relation to aetiology and superimposed microbial infection. Clin Exp Immunol 82, 479-84.
18. Ding AH, Nathan CF, Stuehr DJ (1988) Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidences for independent production. J Immunol 141, 2407-12.
19. Dudley FJ, Fox RA, Sherlock S (1972) Cellular immunity and hepatitis-associated, Australia antigen liver disease. Lancet i, 723-6.
20. Galanos C, Freudenberg MA, Reutter W (1979) Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc Natl Acad Sci USA 76, 5939-43.
21. Galle PR, Hofmann WJ, Walczak H et al. (1995) Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J Exp Med 182, 1223-30.
22. Gartner F, Leist M, Lohse AW, Germann PG, Tiegs G (1995) Concanavalin A-induced T-cell-mediated hepatic injury in mice: The role of tumor necrosis factor. Hepatology 21, 190-8.
23. Hewett JA, Jean PA, Kunkel SL, Roth RA (1993) Relationship between tumor necrosis factor-α and neutrophils in endotoxin-induced liver injury. Am J Physiol 265, G1011-G1015.
24. Hirt B (1967) Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol 26, 365-9.
25. Iragi F, Teale A (1997) Cloning and sequencing of the TNFα genes of three inbred mouse strains, Immunogenetics 45, 459-61.
26. Irie H, Mori W (1986) Fatal hepatic necrosis after shock. Acta Pathol Jpn 36, 363-74.
27. Irie H, Harada Y, Yoshihashi H et al. (1988) Spread of herpes simplex virus type 1 (Miyama +GC strain) to the central nervous system after intraperitoneal inoculation: The role of the myenteric plexus of the gut. Arch Virol 105, 247-57.
28. Irie H, Harada Y, Kataoka M et al. (1992) Efficacy of oral administration of live herpes simplex virus type 1 as a vaccine. J Virol 66, 2428-34.
29. Irie H, Koyama AH, Kubo H et al. (1998) Herpes simplex virus hepatitis in macrophage-depleted mice: The role of massive, apoptotic cell death in pathogenesis. J Gen Virol 79, 1225-31.
30. Jaeschke H, Fisher MA, Lawson A, Simmons CA, Farhood A, Jones DA (1998) Activation of caspase 3 (CPP32)-like proteases is essential for (1999) TNF-α-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model. J Immunol 160, 3480-6.
31. Jones AL, Selby P (1989) Tumor necrosis factor: Clinical relevance. Cancer Surv 8, 817-36.
32. Kimura K, Ando K, Tomita E et al. (1999) Elevated intracellular IFN-γ levels in circulating CDS+ lymphocytes in patients with fulminant hepatitis. J Hepatol 31, 579-3.
33. Kordula T, Bugno M, Rydel RE, Travis J (2000) Mechanism of interleukin-1 and tumor necrosis factor alpha-dependent regulation of the alpha 1-antichymotrypsin gene in human astrocytes. J Nuerosci 15, 7510-16.
34. Ksontini RDB, Colagiovanni MD, Josephs CK et al. (1998) Disparate role for TNF-α and Fas ligand in concanavalin A-induced hepatitis. J Immunol 160, 4082-9.
35. Lara-Pezzi E, Majano PL, Gomez-Gonzalo M et al. (1998) The hepatitis B virus X protein up-regulates tumor necrosis factor alpha gene expression in hepatocytes. Hepatology 28, 1013-21.
36. Leist MF, Gantner I, Bohlinger PG, Germann G, Tiegs A, Wendel A (1994). Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-α requires transcriptional arrest. J Immunol 153, 1778-88.
37. Leist M, Gantner F, Bohlinger I, Tiegs G, Germann G, Wendel A (1995) Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol 146, 1220-34.
38. Maier R, Bilbe G, Rediske J, Lotz M (1994) Inducible nitric oxide synthase from human articular chondrocytes: cDNA cloning and analysis of mRNA expression. Biochim Biophys Acta 1208, 145-50.
39. Melkonyan H, Hofmann HA, Nacken W, Sorg C, Klempt M (1998) The gene encoding the myeloid-related protein 14 (MRP 14), a calcium-binding protein expressed in granulo-cytes and monocytes, contains a potent enhancer element in the first intron. J Biol Chem 273, 27 026-32.
40. Mori W, Shiga J, Irie H (1986) Shwartzman reactions as pathogenic mechanism in fulminant hepatitis. Semin Liver Dis 6, 267-76.
41. Murray LJ, Lee R, Martens C (1990) In vivo cytokine gene expression in T cell subsets of autoimmune MRL/Mp-lpr/lpr mouse. Eur J Immunol 20, 163-70.
42. Muto Y, Nouri-Aria KT, Meager A, Alexander GJ, Eddleston AL, Williams R (1988) Enhanced tumor necrosis factor and interleukin-1 in fulminant hepatic failure. Lancet ii, 72-74.
43. Nakaki M, Iwai H, Naiki T, Ohnishi H, Muto Y, Moriwaki H (2000) High levels of serum interleukin-10 and tumor necrosis factor-α and associated with fatality in fulminant hepatitis. J Infect Dis 182, 1103-8.
44. Nu S, Kamahora J (1961) Studies on the growth of newly isolated herpes simplex virus in vivo. Biken J 4, 75-96.
45. Nowoslawiski A, Krawczynski K, Madalinski K (1972) Tissue localization of Australia antigen immune complexes in acute and chronic hepatitis and liver cirrhosis. Am J Pathol 68, 31-49.
46. Ogasawara J, Watanabe-Fukunaga R, Adachi M et al. (1993) Lethal effect of the anti-Fas antibody in mice. Nature 364, 806-7.
47. Ogata M, Matsui T, Kita T, Shigematsu A (1999) Carrageenan primes leukocytes to enhance lipopolysaccharide-induced tumor necrosis factor alpha production. Infect Immun 67, 3284-9.
48. Quinn JP, McGeoch D (1985) DNA sequence of region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein. Nucleic Acids Res 13, 8143-63.
49. Ryo K, Kamogawa Y, Ikeda I et al. (2000) S ignificance of Fas antigen-mediated apoptosis in human fulminant hepatic failure. Am J Gastroenterol 95, 2047-55.
50. Saad B, Frei K, Scholl FA, Fontana A, Maier P (1995) Hepatocyte-derived interleukin-6 and tumor necrosis factor-á mediate the lipopolysaccharide-induced acute-phase response and nitric oxide release by cultured rat hepatocytes. Eur J Biochem 229, 349-355.
51. Seif I, DeMaeyer-Guignard J (1986) Structure and expression of a new murine interferon-alpha gene. MuiFN-alpha-1-9. Gene 43, 111-21.
52. Shapiro L, Clark BD, Orencole SF, Poutsiaka DD, Granowitz EV, Dinarello CA (1993) Detection of tumor necrosis factor soluble receptor p55 in blood samples from healthy and endotoxemic humans. J Infect Dis 167, 1344-50.
53. Song E, Lee S-K, Wang J et al (2003) RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 9, 347-51.
54. Tanabe O, Akira S, Kamiya T, Wong GG, Hirano T, Kishimoto T (1988) Genetic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human. J Immunol 141, 3875-81.
55. Tokushige K, Yamaguchi N, Ikeda I, Hashimoto E, Yamauchi K, Hayashi N (2000) Significance of soluble TNF receptor-l in acute-type fulminant hepatitis. Am J Gastroenterol 95, 2040-6.
56. Trautwein C, Rakemann T, Brenner DA et al. (1998) Concanavalin A-induced liver cell damage: Activation of intracellular pathways triggered by tumor necrosis factor in mice. Gastroenterology 114, 1035-45.
57. Wang JH, Redmond HP, Wu QD, Bouchier-Hayes D (1998) Nitric oxide mediates hepatocyte injury. Arn J Physiol 275, G1117-G1126.
58. Watanabe-Fukunaga R, Brannan Cl, Itoh N et al. (1992) The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J Immunol 148, 1274-97.
59. Weller A, Isenmann S, Vestweber D (1992) Cloning of the mouse endothelial selectins: Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha. J Biol Chem 267, 15 176-83.
60. Wong GHW, Goeddel DV (1986) Tumor necrosis factor α and β inhibit virus replication and synergize with interferons. Nature 323, 819-22.