Concanavalin A-induced liver cell damage: Activation of intracellular pathways triggered by tumor necrosis factor in mice

Gastroenterology

Volumn 114, Issue 5, 1998, Pages 1035-1045

  Trautwein, C ^a   Rakemann, T ^a   Brenner, D A ^a   Streetz, K ^a   Licato, L ^a   Manns, M P ^a   Tiegs, G ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAVALIN A; DNA FRAGMENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ANTIBODY; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA BINDING; LIVER CELL DAMAGE; MALE; MOUSE; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL;

EID: 0031958385     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70324-5     Document Type: Article

References (39)

1. PR Galle WJ Hofmann H Walczak H Schaller G Otto W Stremmel PH Krammer L Runkel Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage J Exp Med 182 1995 1223 1230
2. G Tiegs J Hentschel A Wendel A T cell-dependent experimental liver injury in mice inducible by concanavalin A J Clin Invest 90 1992 196 203
3. F Gantner M Leist AW Lohse PG Germann A Tiegs Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor Hepatology 21 1995 190 198
4. M Leist F Gantner S Jilg A Wendel Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release J Immunol 154 1995 1307 1316
5. H Mizuhara E O'Neill N Seki T Ogawa C Kusunoki K Otsuka S Satoh M Niwa H Senoh H Fujiwara T-cell activation-associated hepatic-injury: mediation by tumor necrosis factor and protection by interleukin 6 J Exp Med 179 1994 1529 1537
6. B Beutler C van Huffel Unraveling function in the TNF ligand and receptor families Science 264 1994 667 668
7. NTR: a receptor after all Science 272 1996 506 507
8. H Hsu HB Shu MG Pan DV Goedell TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways Cell 84 1996 299 308
9. A Park VR Baichwal Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD J Biol Chem 271 1996 9858 9862
10. AM Chinnaiyan CG Tepper MF Seldin K O'Rourke FC Kischkel S Hellbardt PH Krammer ME Peter VM Dixit FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis J Biol Chem 271 1996 4961 4965
11. Z-G Liu H Hsu DV Goeddel M Karin Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death Cell 87 1996 565 576
12. Hsu H, Huang J, Shu H-B, Baichwal V, Goedell DV. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 199;4:387-396.
13. M Rothe V Sarma VM Dixit DV Goedell TRAF2 mediated activation of NF-κB by TNF receptor 2 and CD40 Science 269 1995 1424 1427
14. C Trautwein T Rakemann A Pietrangelo J Plümpe G Montosi MP Manns C/EBP-β/LAP controls downregulation of albumin gene transcription during liver regeneration J Biol Chem 271 1996 22262 22270
15. C Trautwein D Walker J Plümpe MP Manns Transactivation of LAP/NF-IL6 is mediated by an acidic domain in the N-terminal part of the protein J Biol Chem 270 1995 15130 15136
16. C Trautwein C Caelles P van der Geer T Hunter M Karin M Chojkier Transactivation by LAP/NF-IL6 is enhanced by phosphorylation of its activation domain Nature 364 1993 544 547
17. C Trautwein G Gerken H Löhr K-H Meyer zum Büschenfelde MP Manns Lack of surface expression for the B-cell autoepitope of cytochrome P450 IID6 evidenced by flow cytometry Z Gastroenterol 31 1993 225 230
18. JK Westwick DA Brenner Methods for analyzing c-Jun kinase Methods Enzymol 255 1995 342 359
19. Y-R Chen CF Meyer TH Tan Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in γ radiation-induced apoptosis J Biol Chem 271 1996 631 634
20. NL Johnson AM Gardner KM Diener CA Lange-Carter J Gleavy MB Jarpe A Minden M Karin LI Zon GL Johnson Signal transduction pathways regulated by mitogen-activated/extracellular response kinase induce cell death J Biol Chem 271 1996 3229 3237
21. KM Latinis GA Koretzky Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells Blood 87 1996 871 875
22. DT Denhardt Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling Biochem J 318 1996 729 747
23. T Hunter M Karin Control of transcription factor activity by protein phosphorylation Cell 70 1992 375 387
24. P Angel K Hattori T Smeal M Karin The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1 Cell 55 1988 875 885
25. S Küsters F Gantner G Künstle G Tiegs Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A Gastroenterology 111 1996 462 471
26. S Küsters M Grell G Künstle G Kollias H Blüthmann G Tiegs The role of membrane-bound TNF in concanavalin A-induced T cell-dependent liver injury in mice (abstr) Arch Pharm 355 1997 R85
27. JK Westwick AE Bielawska G Dbaibo YA Hannun DA Brenner Ceramide activates the stress-activated protein kinases J Biol Chem 270 1995 22689 22692
28. Z Xia M Dickens Raingeaud RJ Davis ME Greenberg Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis Science 270 1995 1326 1331
29. M Verheij R Bose XH Lin B Yoa WD Jarvis S Grant MJ Birrer E Szabo LI Zon JM Kyriakis A Halmovitz-Friedman Z Fuks RN Kolesnick Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis Nature 380 1996 75 79
30. M Wu H Lee RE Bellas SL Schauer M Arsura D Katz MJ FitzGerald TL Rothstein DH Sherr GE Sonnenstein Inhibition of NF-κB/Rel induces apoptosis of murine B cells EMBO J 15 1996 4682 4690
31. CH Wang MW Mayo AS Baldwin TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB Science 274 1996 784 787
32. AA Beg D Baltimore An essential role for NF-κB in preventing TNF-α-induced cell death Science 274 1996 782 784
33. DJ van Antwerp SJ Martin T Kafri DR Green IM Verma Suppression of TNF-α-induced apoptosis by NF-κB Science 274 1996 780 782
34. R Taub Liver regeneration 4: transcriptional control of liver regeneration FASEB J 10 1996 413 427
35. AA Beg WC Sha RT Bronson S Gosh D Baltimore Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B Nature 376 1995 167 170
36. JF Bromberg CM Horvath Z Wen RD Schreiber JE Darnell Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon α and interferon γ Proc Natl Acad Sci 93 1996 7673 7678
37. N Itoh S Yonehara A Ishii M Yonehara SI Mizuchima M Sameshima A Hase Y Seto S Nagata The polypeptide encoded by the cDNA for human cell surface Fas can mediate apoptosis Cell 66 1991 2333 2343
38. T Suda S Nagata Purification and characterization of the Fasligand that induces apoptosis J Exp Med 179 1994 873 879
39. AM Chinnaiyan K O'Rourke M Tewari VM Dixit FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis Cell 81 1995 505 512