Effect of fraxetin on antioxidant defense and stress proteins in human neuroblastoma cell model of rotenone neurotoxicity. Comparative study with myricetin and N-acetylcysteine

Toxicology and Applied Pharmacology

Volumn 209, Issue 3, 2005, Pages 214-225

  Molina Jiménez, María Francisca ^a   Sánchez Reus, María Isabel ^a   Cascales, María ^a   Andrés, David ^a   Benedí, Juana ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Antioxidant enzymes; Parkinson's disease; ROS; Rotenone

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; COUMARIN DERIVATIVE; FRAXETIN; FREE RADICAL; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEAT SHOCK PROTEIN 70; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MYRICETIN; ROTENONE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INCUBATION TIME; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; NORTHERN BLOTTING; OXIDATIVE STRESS; PROTEIN CONTENT; PROTEIN EXPRESSION; RNA ANALYSIS; WESTERN BLOTTING;

ACETYLCYSTEINE; ANTIOXIDANTS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CATALASE; CHEMILUMINESCENT MEASUREMENTS; COUMARINS; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; FLOW CYTOMETRY; FLUORESCENCE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOBLOTTING; MITOCHONDRIA; NEUROBLASTOMA; REACTIVE OXYGEN SPECIES; ROTENONE; SUPEROXIDE DISMUTASE; TUMOR CELLS, CULTURED;

EID: 28244439215     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.04.009     Document Type: Article

References (52)

1. H. Aebi Catalase in vitro Methods Enzymol. 105 1984 121 126
2. S.A. Aherne, and N.M. O'Brien Protection by the flavonoids myricetin, quercetin, and rutin against hydrogen peroxide-induced DNA damage in Caco-2 and Hep G2 cells Nutr. Cancer 34 1999 160 166
3. R.M. Amasino Acceleration of nucleic acid hybridization rate by polyethylene glycol Anal. Biochem. 152 1986 304 307
4. D. Andres, and M. Cascales Novel mechanism of Vitamin E protection against cyclosporine A cytotoxicity in cultured rat hepatocytes Biochem. Pharmacol. 64 2002 267 276
5. D. Andres, A.M. Alvarez, C. Diez-Fernandez, A. Zaragoza, and M. Cascales HSP70 induction by cyclosporine A in cultured rat hepatocytes: effect of vitamin E succinate J. Hepatol. 33 2000 570 579
6. G. Barja de Quiroga, R. Perez-Campo, and M. Lopez-Torres Changes on cerebral antioxidant enzymes, peroxidation, and the glutathione system of frogs after aging and catalase inhibition J. Neurosci. Res. 26 1990 370 376
7. V. Bashkatova, M. Alam, A. Vanin, and W.J. Schmidt Chronic administration of rotenone increases levels of nitric oxide and lipid peroxidation products in rat brain Exp. Neurol. 186 2004 235 241
8. R. Betarbet, T.B. Sherer, G. MacKenzie, M. Garcia-Osuna, A.V. Panov, and J.T. Greenamyre Chronic systemic pesticide exposure reproduces features of Parkinson's disease Nat. Neurosci. 3 2000 1301 1306
9. P. Bremner, and M. Heinrich Natural products as targeted modulators of the nuclear factor-kappaB pathway J. Pharm. Pharmacol. 54 2002 453 472
10. D.S. Cassarino, C.P. Fall, R.H. Swerdlow, T.S. Smith, E.M. Halvorsen, S.W. Millar, J.P. Parks, W.D. Parker, and J.P. Bennett Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease Biochim. Biophys. Acta 1362 1997 77 86
11. C.C. Chen, M.P. Chow, W.C. Huang, Y.C. Lin, and Y.J. Chang Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships Mol. Pharmacol. 66 2004 683 693
12. Y.J. Choi, J.S. Kang, J.H. Park, Y.J. Lee, J.S. Choi, and Y.H. Kang Polyphenolic flavonoids differ in their antiapoptotic efficacy in hydrogen peroxide-treated human vascular endothelial cells J. Nutr. 133 2003 985 991
13. P. Chomczynski, and N. Sacchi Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162 1987 156 159
14. E. Corsini, L. Lucchi, M. Binaglia, B. Viviani, C. Bevilacqua, G. Monastra, M. Marinovich, and C.L. Galli Cloricromene, a semi-synthetic coumarin derivative, inhibits tumor necrosis factor-alpha production at a pre-transcriptional level Eur. J. Pharmacol. 27 2001 231 237
15. R. Del Maestro, and W. McDonald Distribution of superoxide dismutase, glutathione peroxidase and catalase in developing rat brain Mech. Ageing Dev. 41 1987 29 38
16. D.T. Dexter, C.J. Carter, F.R. Wells, F. Javoy-Agid, Y. Agid, A. Lees, P. Jenner, and C.D. Marsden Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease J. Neurochem. 52 1989 381 389
17. B. Fernandez-Puntero, I. Barroso, I. Iglesias, J. Benedi, and A. Villar Antioxidant activity of fraxetin: in vivo and ex vivo parameters in normal situation versus induced stress Biol. Pharm. Bull. 24 2001 777 784
18. Z. Gao, K. Huang, X. Yang, and H. Xu Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi Biochim. Biophys. Acta 1472 1999 643 650
19. Z. Gao, K. Huang, and H. Xu Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells Pharmacol. Res. 43 2001 173 178
20. W.A. Gunzler, H. Kremers, and L. Flohe An improved coupled test procedure for glutathione peroxidase (EC 1-11-1-9-) in blood Z. Klin. Chem. Klin. Biochem. 12 1974 444 448
21. J. Hladovec Differentiation of in vitro and in vivo effects of a flavonoid on endothelial cell counts Arzneimittelforschung 27 1977 1142 1144
22. H. Hong, and G.Q. Liu Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin Life Sci. 74 2004 2959 2973
23. K. Ishige, D. Schubert, and Y. Sagara Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms Free Radical Biol. Med. 15 2001 433 446
24. S.D. Klein, and B. Brune Heat-shock protein 70 attenuates nitric oxide-induced apoptosis in RAW macrophages by preventing cytochrome c release Biochem. J. 362 2002 635 641
25. R. Kurosaki, Y. Muramatsu, H. Kato, and T. Araki Biochemical, behavioral and immunohistochemical alterations in MPTP-treated mouse model of Parkinson's disease Pharmacol. Biochem. Behav. 78 2004 143 153
26. Y. Kushnareva, A.N. Murphy, and A. Andreyev Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state Biochem. J. 368 2002 545 553
27. Y. Levites, M.B. Youdim, G. Maor, and S. Mandel Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures Biochem. Pharmacol. 63 2002 21 29
28. S. Mandel, and M.B. Youdim Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases Free Radical Biol. Med. 37 2004 304 317
29. S. Mandel, E. Grunblatt, P. Riederer, M. Gerlach, Y. Levites, and M.B. Youdim Neuroprotective strategies in Parkinson's disease: an update on progress CNS Drugs 17 2003 729 762
30. S. Martín-Aragón, J.M. Benedi, and A.M. Villar Modifications on antioxidant capacity and lipid peroxidation in mice under fraxetin treatment J. Pharm. Pharmacol. 49 1997 49 52
31. S. Martín-Aragón, J.M. Benedi, and A.M. Villar Effects of fraxetin on glutathione redox status Z. Naturforsch. 52 1997 55 59
32. M.F. Molina-Jimenez, M.I. Sanchez-Reus, and J. Benedi Effect of fraxetin and myricetin on rotenone-induced cytotoxicity in SH-SY5Y cells: comparison with N-acetylcysteine Eur. J. Pharmacol. 472 2003 81 87
33. M.F. Molina-Jimenez, M.I. Sanchez-Reus, D. Andres, M. Cascales, and J. Benedi Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells Brain Res. 1009 2004 9 16
34. K. Nakamura, V.P. Bindokas, D. Kowlessur, M. Elas, S. Milstien, J.D. Marks, H.J. Halpern, and U.J. Kang Tetrahydrobiopterin scavenges superoxide in dopaminergic neurons J. Biol. Chem. 276 2001 34402 34407
35. S. Ozgova, J. Hermanek, and I. Gut Different antioxidant effects of polyphenols on lipid peroxidation and hydroxyl radicals in the NADPH-Fe-ascorbate- and Fe-microsomal systems Biochem. Pharmacol. 66 2003 1127 1137
36. M. Paya, B. Halliwell, and J.R. Hoult Interactions of a series of coumarins with reactive oxygen species. Scavenging of superoxide, hypochlorous acid and hydroxyl radicals Biochem. Pharmacol. 44 1992 205 214
37. M. Paya, B. Halliwell, and J.R. Hoult Peroxyl radical scavenging by a series of coumarins Free Radical Res. Commun. 17 1992 293 298
38. M. Paya, M.L. Ferrandiz, F. Miralles, C. Montesinos, A. Ubeda, and M.J. Alcaraz Effects of coumarin derivatives on superoxide anion generation Arzneimittelforschung 43 1993 655 658
39. J. Pedraza-Chaverri, O.N. Medina-Campos, M.A. Granados-Silvestre, P.D. Maldonado, I.M. Olivares-Corichi, and R. Hernandez-Pando Garlic ameliorates hyperlipidemia in chronic aminonucleoside nephrosis Mol. Cell. Biochem. 211 2000 69 77
40. C. Perier, J. Bove, M. Vila, and S. Przedborski The rotenone model of Parkinson's disease Trends Neurosci. 26 2003 345 346
41. D.J. Quigney, A.M. Gorman, and A. Samali Heat shock protects PC12 cells against MPP+ toxicity Brain Res. 12 2003 133 139
42. T.A. Seaton, J.M. Cooper, and A.H. Schapira Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors Brain Res. 777 1997 110 118
43. T.B. Sherer, P.A. Trimmer, K. Borland, J.K. Parks, J.P. Bennett, and J.B. Tuttle Chronic reduction in complex I function alters calcium signaling in SH-SY5Y neuroblastoma cells Brain Res. 891 2001 94 105
44. T.B. Sherer, R. Betarbet, C.M. Testa, B.B. Seo, J.R. Richardson, J.H. Kim, G.W. Miller, T. Yagi, A. Matsuno-Yagi, and J.T. Greenamyre Mechanism of toxicity in rotenone models of Parkinson's disease J. Neurosci. 23 2003 10756 10764
45. T. Shibuya, Y. Watenabe, K.A. Nalley, A. Fusco, and B. Salafasky The BCA protein determination system: an analysis of several buffers, incubation temperature and protein standards Tokyo Ika Daigaku Zasshi 47 1989 677 682
46. J.V. Smith, and Y. Luo Elevation of oxidative free radicals in Alzheimer's disease models can be attenuated by Ginkgo biloba extract EGb 761 J. Alzheimer's Dis. 5 2003 287 300
47. J.L. Tilly, and K.I. Tilly Inhibitors of oxidative stress mimic the ability of follicle-stimulating hormone to suppress apoptosis in cultured rat ovarian follicles Endocrinology 136 1995 242 252
48. S.H. Tsai, Y.C. Liang, S.Y. Lin-Shiau, and J.K. Lin Suppression of TNFalpha-mediated NFkappaB activity by myricetin and other flavonoids through downregulating the activity of IKK in ECV304 cells J. Cell. Biochem. 74 1999 606 615
49. R.J. Williams, J.P. Spencer, and C. Rice-Evans Flavonoids: antioxidants or signalling molecules? Free Radical Biol. Med. 36 2004 838 849
50. A. Zaragoza, C. Diez-Fernandez, A.M. Alvarez, D. Andres, and M. Cascales Effect of N-acetylcysteine and deferoxamine on endogenous antioxidant defense system gene expression in a rat hepatocyte model of cocaine cytotoxicity Biochim. Biophys. Acta 1496 2000 183 195
51. X.P. Zhang, and E. Glaser Interaction of plant mitochondrial and chloroplast signal peptides with the Hsp70 molecular chaperone Trends Plant Sci. 7 2002 14 21
52. Y. Zhou, G. Gu, D.R. Goodlett, T. Zhang, C. Pan, T.J. Montine, K.S. Montine, R.H. Aebersold, and J. Zhang Analysis of alpha-synuclein-associated proteins by quantitative proteomics J. Biol. Chem. 10 2004 39155 39164