메뉴 건너뛰기




Volumn 15, Issue 6, 2005, Pages 388-396

The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells

Author keywords

Colorectal cancer; IGF; IGF I receptor; p53; p63; p73; Transcription

Indexed keywords

MUTANT PROTEIN; PROTEIN P63; PROTEIN P73; SOMATOMEDIN C RECEPTOR;

EID: 28044468153     PISSN: 10966374     EISSN: 15322238     Source Type: Journal    
DOI: 10.1016/j.ghir.2005.07.005     Document Type: Article
Times cited : (51)

References (52)
  • 1
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • D. LeRoith H. Werner D. Beitner-Johnson C.T. Roberts Jr. Molecular and cellular aspects of the insulin-like growth factor I receptor Endocr. Rev. 16 1995 143-163
    • (1995) Endocr. Rev. , vol.16 , pp. 143-163
    • LeRoith, D.1    Werner, H.2    Beitner-Johnson, D.3    Roberts Jr., C.T.4
  • 2
    • 0025028901 scopus 로고
    • Cellular pattern of insulin-like growth factor I and type I IGF receptor gene expression in early organogenesis: Comparison with IGF-II gene expression
    • C.A. Bondy H. Werner C.T. Roberts Jr. D. LeRoith Cellular pattern of insulin-like growth factor I and type I IGF receptor gene expression in early organogenesis: Comparison with IGF-II gene expression Mol. Endocrinol. 4 1990 1386-1398
    • (1990) Mol. Endocrinol. , vol.4 , pp. 1386-1398
    • Bondy, C.A.1    Werner, H.2    Roberts Jr., C.T.3    LeRoith, D.4
  • 4
    • 12144290914 scopus 로고    scopus 로고
    • Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
    • C.S. Mitsiades N.S. Mitsiades C.J. McMullan et al. Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors Cancer Cell 5 2004 221-230
    • (2004) Cancer Cell , vol.5 , pp. 221-230
    • Mitsiades, C.S.1    Mitsiades, N.S.2    McMullan, C.J.3
  • 5
    • 0031838925 scopus 로고    scopus 로고
    • Hormonal control of programmed cell death/apoptosis
    • W. Kiess B. Gallaher Hormonal control of programmed cell death/apoptosis Eur. J. Endocrinol. 138 1998 482-491
    • (1998) Eur. J. Endocrinol. , vol.138 , pp. 482-491
    • Kiess, W.1    Gallaher, B.2
  • 6
    • 0037300604 scopus 로고    scopus 로고
    • The IGF-I receptor gene: A molecular target for disrupted transcription factors
    • H. Werner C.T. Roberts Jr. The IGF-I receptor gene: A molecular target for disrupted transcription factors Gene. Chromosome. Cancer 36 2003 113-120
    • (2003) Gene. Chromosome. Cancer , vol.36 , pp. 113-120
    • Werner, H.1    Roberts Jr., C.T.2
  • 7
    • 0025337031 scopus 로고
    • Cloning and characterization of the proximal promoter region of the rat insulin-like growth factor I receptor gene
    • H. Werner B. Stannard M.A. Bach D. LeRoith C.T. Roberts Jr. Cloning and characterization of the proximal promoter region of the rat insulin-like growth factor I receptor gene Biochem. Biophys. Res. Commun. 169 1990 1021-1027
    • (1990) Biochem. Biophys. Res. Commun. , vol.169 , pp. 1021-1027
    • Werner, H.1    Stannard, B.2    Bach, M.A.3    LeRoith, D.4    Roberts Jr., C.T.5
  • 8
    • 0026801581 scopus 로고
    • Structural and functional analysis of the insulin-like growth factor I receptor gene promoter
    • H. Werner M.A. Bach B. Stannard C.T. Roberts Jr. D. LeRoith Structural and functional analysis of the insulin-like growth factor I receptor gene promoter Mol. Endocrinol. 6 1992 1545-1558
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1545-1558
    • Werner, H.1    Bach, M.A.2    Stannard, B.3    Roberts Jr., C.T.4    LeRoith, D.5
  • 10
    • 0027278677 scopus 로고
    • Increased expression of the insulin-like growth factor-I receptor gene, IGFIR, in Wilms' tumor is correlated with modulation of IGFIR promoter activity by the WT1 Wilms' tumor gene product
    • H. Werner G.G. Re I.A. Drummond et al. Increased expression of the insulin-like growth factor-I receptor gene, IGFIR, in Wilms' tumor is correlated with modulation of IGFIR promoter activity by the WT1 Wilms' tumor gene product Proc. Natl. Acad. Sci. USA 90 1993 5828-5832
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5828-5832
    • Werner, H.1    Re, G.G.2    Drummond, I.A.3
  • 11
    • 3843050225 scopus 로고    scopus 로고
    • Transcriptional activation of the IGF-I receptor gene by the Kruppel-like factor-6 (KLF6) tumor suppressor protein: Potential interactions between KLF6 and p53
    • M. Rubinstein G. Idelman S.R. Plymate G. Narla S.L. Friedman H. Werner Transcriptional activation of the IGF-I receptor gene by the Kruppel-like factor-6 (KLF6) tumor suppressor protein: Potential interactions between KLF6 and p53 Endocrinology 145 2004 3769-3777
    • (2004) Endocrinology , vol.145 , pp. 3769-3777
    • Rubinstein, M.1    Idelman, G.2    Plymate, S.R.3    Narla, G.4    Friedman, S.L.5    Werner, H.6
  • 12
    • 0037464450 scopus 로고    scopus 로고
    • BRCA1-Sp1 interactions in transcriptional regulation of the IGF-IR gene
    • S. Abramovitch T. Glaser T. Ouchi H. Werner BRCA1-Sp1 interactions in transcriptional regulation of the IGF-IR gene FEBS Lett. 541 2003 149-154
    • (2003) FEBS Lett. , vol.541 , pp. 149-154
    • Abramovitch, S.1    Glaser, T.2    Ouchi, T.3    Werner, H.4
  • 13
    • 0029757120 scopus 로고    scopus 로고
    • Wild type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene
    • H. Werner E. Karnieli F.J. Rauscher III D. LeRoith Wild type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene Proc. Natl. Acad. Sci. USA 93 1996 8318-8323
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8318-8323
    • Werner, H.1    Karnieli, E.2    Rauscher III, F.J.3    LeRoith, D.4
  • 14
    • 0031769052 scopus 로고    scopus 로고
    • p53 regulates IGF-I receptor expression and IGF-I induced tyrosine phosphorylation in an osteosarcoma cell line: Interaction between p53 and Sp1
    • C. Ohlsson N. Kley H. Werner D. LeRoith p53 regulates IGF-I receptor expression and IGF-I induced tyrosine phosphorylation in an osteosarcoma cell line: Interaction between p53 and Sp1 Endocrinology 139 1998 1101-1107
    • (1998) Endocrinology , vol.139 , pp. 1101-1107
    • Ohlsson, C.1    Kley, N.2    Werner, H.3    LeRoith, D.4
  • 15
    • 0034665348 scopus 로고    scopus 로고
    • Increased expression of insulin-like growth factor I receptor in malignant cells expressing aberrant p53: Functional impact
    • L. Girnita A. Girnita B. Brodin et al. Increased expression of insulin-like growth factor I receptor in malignant cells expressing aberrant p53: Functional impact Cancer Res. 60 2000 5278-5283
    • (2000) Cancer Res. , vol.60 , pp. 5278-5283
    • Girnita, L.1    Girnita, A.2    Brodin, B.3
  • 16
    • 0031036879 scopus 로고    scopus 로고
    • The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal
    • M. Prisco A. Hongo M.G. Rizzo A. Sacchi R. Baserga The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal Mol. Cell. Biol. 17 1997 1084-1092
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1084-1092
    • Prisco, M.1    Hongo, A.2    Rizzo, M.G.3    Sacchi, A.4    Baserga, R.5
  • 17
    • 0034927749 scopus 로고    scopus 로고
    • p53 family update: p73 and p63 develop their own identities
    • M.S. Irwin W.G. Kaelin p53 family update: P73 and p63 develop their own identities Cell Growth Diff. 12 2001 337-349
    • (2001) Cell Growth Diff. , vol.12 , pp. 337-349
    • Irwin, M.S.1    Kaelin, W.G.2
  • 18
    • 0034576495 scopus 로고    scopus 로고
    • p63 and p73: p53 mimics, menaces and more
    • A. Yang F. McKeon p63 and p73: P53 mimics, menaces and more Nat. Rev. 1 2000 199-207
    • (2000) Nat. Rev. , vol.1 , pp. 199-207
    • Yang, A.1    McKeon, F.2
  • 19
    • 0032161624 scopus 로고    scopus 로고
    • p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • A. Yang M. Kaghad Y. Wang et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities Mol. Cell 2 1998 305-316
    • (1998) Mol. Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3
  • 20
    • 0031564954 scopus 로고    scopus 로고
    • p73 is a simian p53-related protein that can induce apoptosis
    • C.A. Jost M.C. Marin W.G. Kaelin Jr. p73 is a simian p53-related protein that can induce apoptosis Nature 389 1997 191-194
    • (1997) Nature , vol.389 , pp. 191-194
    • Jost, C.A.1    Marin, M.C.2    Kaelin Jr., W.G.3
  • 21
    • 0030812331 scopus 로고    scopus 로고
    • Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
    • M. Kaghad H. Bonnet A. Yang et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers Cell 90 1997 809-819
    • (1997) Cell , vol.90 , pp. 809-819
    • Kaghad, M.1    Bonnet, H.2    Yang, A.3
  • 22
    • 0030884751 scopus 로고    scopus 로고
    • A novel protein with strong homology to the tumor suppressor p53
    • H. Schmale C. Bamberger A novel protein with strong homology to the tumor suppressor p53 Oncogene 15 1997 1363-1367
    • (1997) Oncogene , vol.15 , pp. 1363-1367
    • Schmale, H.1    Bamberger, C.2
  • 23
    • 0037077721 scopus 로고    scopus 로고
    • Differential regulation of transcription and induction of programmed cell death by human p53-family members p63 and p73
    • S. Dietz K. Rother C. Bamberger H. Schmale J. Mossner K. Engeland et al. Differential regulation of transcription and induction of programmed cell death by human p53-family members p63 and p73 FEBS Lett. 525 2002 93-99
    • (2002) FEBS Lett. , vol.525 , pp. 93-99
    • Dietz, S.1    Rother, K.2    Bamberger, C.3    Schmale, H.4    Mossner, J.5    Engeland, K.6
  • 24
    • 0035260534 scopus 로고    scopus 로고
    • Differential modulation of cellular and viral promoters by p73 and p53
    • D. Deb A. Lanyi M. Scian et al. Differential modulation of cellular and viral promoters by p73 and p53 Int. J. Oncol. 18 2001 401-409
    • (2001) Int. J. Oncol. , vol.18 , pp. 401-409
    • Deb, D.1    Lanyi, A.2    Scian, M.3
  • 25
    • 10744228945 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor enhances invasion and reduces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway
    • M. Sekharam H. Zhao M. Sun et al. Insulin-like growth factor-I receptor enhances invasion and reduces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway Cancer Res. 63 2003 7708-7716
    • (2003) Cancer Res. , vol.63 , pp. 7708-7716
    • Sekharam, M.1    Zhao, H.2    Sun, M.3
  • 26
    • 0033531765 scopus 로고    scopus 로고
    • Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor-I and IGF-binding protein-3
    • J. Ma M.N. Pollack E. Giovannucci et al. Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor-I and IGF-binding protein-3 J. Natl. Cancer Inst. 91 1999 620-625
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 620-625
    • Ma, J.1    Pollack, M.N.2    Giovannucci, E.3
  • 27
    • 0036157538 scopus 로고    scopus 로고
    • p73 overexpression is a prognostic factor in patients with colorectal adenocarcinoma
    • X.F. Sun p73 overexpression is a prognostic factor in patients with colorectal adenocarcinoma Clin. Cancer Res. 8 2002 165-170
    • (2002) Clin. Cancer Res. , vol.8 , pp. 165-170
    • Sun, X.F.1
  • 28
    • 0033532910 scopus 로고    scopus 로고
    • Expression of p73 and its relation to histopathology and prognosis in hepatocellular carcinoma
    • A. Tannapfel M. Wasner K. Krause et al. Expression of p73 and its relation to histopathology and prognosis in hepatocellular carcinoma J. Natl. Cancer Inst. 91 1999 1154-1158
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1154-1158
    • Tannapfel, A.1    Wasner, M.2    Krause, K.3
  • 29
    • 0036125352 scopus 로고    scopus 로고
    • Role of p73 in malignancy: Tumor suppressor or oncogene
    • T. Stiewe B.M. Putzer Role of p73 in malignancy: Tumor suppressor or oncogene Cell Death Diff. 9 2002 237-245
    • (2002) Cell Death Diff. , vol.9 , pp. 237-245
    • Stiewe, T.1    Putzer, B.M.2
  • 30
    • 0034834092 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: Potential application to gene therapy of colorectal cancer
    • Y. Sasaki I. Morimoto S. Ishida T. Yamashita K. Imai T. Tokino Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: potential application to gene therapy of colorectal cancer Gene Ther. 8 2001 1401-1408
    • (2001) Gene Ther. , vol.8 , pp. 1401-1408
    • Sasaki, Y.1    Morimoto, I.2    Ishida, S.3    Yamashita, T.4    Imai, K.5    Tokino, T.6
  • 31
    • 0032553485 scopus 로고    scopus 로고
    • Requirement for p53 and p21 to sustain G2 arrest after DNA damage
    • F. Bunz A. Dutriaux C. Lengauer et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage Science 282 1998 1497-1501
    • (1998) Science , vol.282 , pp. 1497-1501
    • Bunz, F.1    Dutriaux, A.2    Lengauer, C.3
  • 32
    • 0026587319 scopus 로고
    • Modulation of differentiation-related responses in human colon carcinoma cells by protein kinase inhibitor H-7
    • S. Chakrabarty J.W. Chen X.Y. Chen J.M. Trujillo P.F. Lin Modulation of differentiation-related responses in human colon carcinoma cells by protein kinase inhibitor H-7 Anticancer Res. 12 1992 97-104
    • (1992) Anticancer Res. , vol.12 , pp. 97-104
    • Chakrabarty, S.1    Chen, J.W.2    Chen, X.Y.3    Trujillo, J.M.4    Lin, P.F.5
  • 33
    • 0028318393 scopus 로고
    • Transcriptional repression of the insulin-like growth factor I receptor gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site
    • H. Werner F.J. Rauscher III V.P. Sukhatme I.A. Drummond C.T. Roberts Jr. D. LeRoith Transcriptional repression of the insulin-like growth factor I receptor gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site J. Biol. Chem. 269 1994 12577-12582
    • (1994) J. Biol. Chem. , vol.269 , pp. 12577-12582
    • Werner, H.1    Rauscher III, F.J.2    Sukhatme, V.P.3    Drummond, I.A.4    Roberts Jr., C.T.5    LeRoith, D.6
  • 34
    • 0024829771 scopus 로고
    • Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines
    • A.R. Brasier J.E. Tate J.F. Habener Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines Biotechniques 7 1989 1116-1122
    • (1989) Biotechniques , vol.7 , pp. 1116-1122
    • Brasier, A.R.1    Tate, J.E.2    Habener, J.F.3
  • 35
    • 0032961828 scopus 로고    scopus 로고
    • MDM2 suppresses p73 function without promoting p73 degradation
    • X. Zeng L. Chen C.A. Jost et al. MDM2 suppresses p73 function without promoting p73 degradation Mol. Cell. Biol. 19 1999 3257-3266
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3257-3266
    • Zeng, X.1    Chen, L.2    Jost, C.A.3
  • 37
    • 18544364361 scopus 로고    scopus 로고
    • Physical interaction with human tumor-derived p53 mutants inhibits p63 activities
    • S. Strano G. Fontemaggi A. Costanzo et al. Physical interaction with human tumor-derived p53 mutants inhibits p63 activities J. Biol. Chem. 277 2002 18817-18826
    • (2002) J. Biol. Chem. , vol.277 , pp. 18817-18826
    • Strano, S.1    Fontemaggi, G.2    Costanzo, A.3
  • 38
    • 0035131701 scopus 로고    scopus 로고
    • A subset of tumor-derived mutant forms of p53 downregulate p63 and p73 through a direct interaction with the p53 core domain
    • C. Gaiddon M. Lokshin J. Ahn T. Zhang C.A. Prives A subset of tumor-derived mutant forms of p53 downregulate p63 and p73 through a direct interaction with the p53 core domain Mol. Cell. Biol. 21 2001 1874-1887
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1874-1887
    • Gaiddon, C.1    Lokshin, M.2    Ahn, J.3    Zhang, T.4    Prives, C.A.5
  • 40
    • 0029142836 scopus 로고
    • Regulation of insulin-like growth factor I receptor gene expression by Sp1: Physical and functional interactions of Sp1 at GC boxes and at a CT element
    • D. Beitner-Johnson H. Werner C.T. Roberts Jr. D. LeRoith Regulation of insulin-like growth factor I receptor gene expression by Sp1: Physical and functional interactions of Sp1 at GC boxes and at a CT element Mol. Endocrinol. 9 1995 1147-1156
    • (1995) Mol. Endocrinol. , vol.9 , pp. 1147-1156
    • Beitner-Johnson, D.1    Werner, H.2    Roberts Jr., C.T.3    LeRoith, D.4
  • 41
    • 0036173548 scopus 로고    scopus 로고
    • Circulating IGF-I levels regulate colon cancer growth and metastasis
    • Y. Wu S. Yakar L. Zhao L. Hennighausen D. LeRoith Circulating IGF-I levels regulate colon cancer growth and metastasis Cancer Res. 62 2002 1030-1035
    • (2002) Cancer Res. , vol.62 , pp. 1030-1035
    • Wu, Y.1    Yakar, S.2    Zhao, L.3    Hennighausen, L.4    LeRoith, D.5
  • 43
    • 13144295009 scopus 로고    scopus 로고
    • p73 and p63: Why do we still need them?
    • G. Blandino M. Dobbelstein p73 and p63: Why do we still need them? Cell Cycle 3 2004 886-894
    • (2004) Cell Cycle , vol.3 , pp. 886-894
    • Blandino, G.1    Dobbelstein, M.2
  • 44
    • 0034644195 scopus 로고    scopus 로고
    • High level expression of Del-N-p63: A mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)
    • T. Crook J.M. Nicholls L. Brooks J. O'Nions M.J. Allday High level expression of Del-N-p63: A mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC) Oncogene 19 2000 3439-3444
    • (2000) Oncogene , vol.19 , pp. 3439-3444
    • Crook, T.1    Nicholls, J.M.2    Brooks, L.3    O'Nions, J.4    Allday, M.J.5
  • 45
    • 14844293881 scopus 로고    scopus 로고
    • TAp63 gamma can substitute for p53 in inducing expression of the maspin tumor suppressor
    • K. Spiesbach A. Tannapfel J. Mossner K. Engeland TAp63 gamma can substitute for p53 in inducing expression of the maspin tumor suppressor Int. J. Cancer 114 2004 555-562
    • (2004) Int. J. Cancer , vol.114 , pp. 555-562
    • Spiesbach, K.1    Tannapfel, A.2    Mossner, J.3    Engeland, K.4
  • 46
    • 0034669312 scopus 로고    scopus 로고
    • The tumour suppressor protein p53 can repress transcription of cyclin B
    • K. Krause M. Wasner W. Reinhard et al. The tumour suppressor protein p53 can repress transcription of cyclin B Nucleic Acids Res. 28 2000 4410-4418
    • (2000) Nucleic Acids Res. , vol.28 , pp. 4410-4418
    • Krause, K.1    Wasner, M.2    Reinhard, W.3
  • 47
    • 0041857759 scopus 로고    scopus 로고
    • p21/CDKNIA mediates negative regulation of transcription by p53
    • K. Lohr C. Moritz A. Contente M. Dobbelstein p21/CDKNIA mediates negative regulation of transcription by p53 J. Biol. Chem. 278 2003 32507-32516
    • (2003) J. Biol. Chem. , vol.278 , pp. 32507-32516
    • Lohr, K.1    Moritz, C.2    Contente, A.3    Dobbelstein, M.4
  • 48
    • 0035834651 scopus 로고    scopus 로고
    • p53 homologue p63 represses epidermal growth factor receptor expression
    • H. Nishi M. Senoo K.H. Nishi et al. p53 homologue p63 represses epidermal growth factor receptor expression J. Biol. Chem. 276 2001 41717-41724
    • (2001) J. Biol. Chem. , vol.276 , pp. 41717-41724
    • Nishi, H.1    Senoo, M.2    Nishi, K.H.3
  • 49
    • 1042301369 scopus 로고    scopus 로고
    • Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage
    • H.S. Yoon V.W. Yang Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage J. Biol. Chem. 279 2004 5035-5041
    • (2004) J. Biol. Chem. , vol.279 , pp. 5035-5041
    • Yoon, H.S.1    Yang, V.W.2
  • 50
    • 0032533514 scopus 로고    scopus 로고
    • The potential tumor suppressor p73 differentially regulates cellular p53 target genes
    • J. Zhu J. Jiang W. Zhou X. Chen The potential tumor suppressor p73 differentially regulates cellular p53 target genes Cancer Res. 58 1998 5061-5065
    • (1998) Cancer Res. , vol.58 , pp. 5061-5065
    • Zhu, J.1    Jiang, J.2    Zhou, W.3    Chen, X.4
  • 51
    • 0006598811 scopus 로고    scopus 로고
    • Expression of the vascular endothelial growth factor gene is inhibited by p73
    • B. Salimath D. Marme G. Finkenzeller Expression of the vascular endothelial growth factor gene is inhibited by p73 Oncogene 19 2000 3470-3476
    • (2000) Oncogene , vol.19 , pp. 3470-3476
    • Salimath, B.1    Marme, D.2    Finkenzeller, G.3
  • 52
    • 0033083962 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies
    • W.T. Bellamy L. Richter Y. Frutiger T.M. Grogan Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies Cancer Res. 59 1999 728-733
    • (1999) Cancer Res. , vol.59 , pp. 728-733
    • Bellamy, W.T.1    Richter, L.2    Frutiger, Y.3    Grogan, T.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.