Modulation of PGF2α- and hypoxia-induced contraction of rat intrapulmonary artery by p38 MAPK inhibition: A nitric oxide-dependent mechanism

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 289, Issue 6 33-6, 2005, Pages

  Knock, Greg A ^a   De Silva, Anushika S ^a   Snetkov, Vladimir A ^a   Siow, Richard ^a   Thomas, Gavin D ^a   Shiraishi, Mitsuya ^b   Walsh, Michael P ^b   Ward, Jeremy P T ^a,c   Aaronson, Philip I ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Calcium sensitization; Heat shock protein 27; Intracellular calcium; p38 mitogen activated protein kinase; Prostaglandin F 2 ; Pulmonary artery

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 ETHYL 2 (4 METHOXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA TOXIN; CALCIUM ION; CALCIUM SENSITIZER; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PROSTAGLANDIN F2 ALPHA; UNCLASSIFIED DRUG; CALCIUM; ENZYME INHIBITOR; HEAT SHOCK PROTEIN; HSPB1 PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYTOCIC AGENT; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; HYPOXIA; INHIBITION KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; SMOOTH MUSCLE CONTRACTION; STATISTICAL SIGNIFICANCE; VASOCONSTRICTION; ANIMAL; ANOXIA; CALCIUM SIGNALING; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; METHODOLOGY; MUSCLE CONTRACTION; ORGAN CULTURE TECHNIQUE; PHOSPHORYLATION; STENOSIS, OCCLUSION AND OBSTRUCTION; WISTAR RAT;

ANIMALS; ANOXIA; CALCIUM; CALCIUM SIGNALING; CONSTRICTION, PATHOLOGIC; DINOPROST; ENZYME INHIBITORS; HEAT-SHOCK PROTEINS; MALE; MUSCLE CONTRACTION; NEOPLASM PROTEINS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; ORGAN CULTURE TECHNIQUES; OXYTOCICS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PULMONARY ARTERY; RATS; RATS, WISTAR;

EID: 27944498685     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00094.2005     Document Type: Article

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