Stress causes decrease in vascular relaxation linked with altered phosphorylation of heat shock proteins

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 279, Issue 2 48-2, 2000, Pages

  Fuchs, Leslie C ^a   Giulumian, Ararat D ^a   Knoepp, Louis ^a   Pipkin, Walter ^a   Dickinson, Mary ^a   Hayles, Chad ^a   Brophy, Colleen ^a,b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Behavioral stress; Hypertension; Vascular smooth muscle

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 20; HEAT SHOCK PROTEIN 27; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMOTIONAL STRESS; ENZYME SUBUNIT; FEMALE; HEAT SHOCK RESPONSE; IMMUNOREACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; VASCULAR SMOOTH MUSCLE; VASODILATATION;

EID: 0033865447     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.2000.279.2.r492     Document Type: Article

References (31)

1. Heat shock-related protein, HSP20, is phosphorylated on serine 16 during cyclic nucleotide-dependent relaxation
2. Cyclic nucleotide-dependent vasorelaxation is associated with the phosphorylation of a small heat shock-related protein
3. Stress (heat shock) proteins: Molecular chaperones in cardiovascular biology and disease
4. Impaired cyclic nucleotide-dependent relaxation in human umbilical artery smooth muscle
5. HSP27 is a mediator of sustained smooth muscle contraction in response to bombesin
6. Morphofunctional changes in the noradrengergic innervation of the rat cardiovascular system after varying duration of noise stress
7. Heat shock protein expression in umbilical artery smooth muscle
8. Phosphorylation of the small heat shock-related protein, HSP20, in vascular smooth muscles is associated with changes in the macromolecular associations of HSP20
9. The small heat shock-related protein-20 is an actin-associated protein
10. Thrombin activates MAPKAP2 kinase in vascular smooth muscle
11. Vascular and hemodynamic effects of behavioral stress in borderline hypertensive and Wistar-Kyoto rats
12. Effect of behavioral stress on coronary artery relaxation altered with aging in BHR
13. Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27
14. HSP27 in signal transduction and association with contractile proteins in smooth muscle cells
15. Endothelial-dependent vasodilation is associated with increases in the phosphorylation of a small heat shock protein (HSP20)
16. Exaggerated blood pressure responses during mental stress are associated with enhanced carotid atherosclerosis in middle-aged Finnish men: Findings from the Kuopio ischemic heart disease study
17. Purification and characterization of a 20-kDa protein that is highly homologous to alphaB-crystallin
18. Cellular stress inhibits vascular smooth muscle relaxation
19. Phosphorylation of the 27-kDa heat shock protein via p38 MAP kinase and MAPKAP kinase in smooth muscle
20. Heat shock protein expression in human placenta and umbilical cord
21. Overexpression of the rat inducible 70-kDa heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury
22. Impaired cyclic nucleotide-mediated vasorelaxation may contribute to closure of the human umbilical artery after birth
23. Discovery of the heat shock response
24. Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy
25. Lesions of the anteroventral third ventricle (AV3V) and development of stress-induced hypertension in the borderline hypertensive rat
26. The borderline hypertensive rat (BHR) as a model for environmentally induced hypertension: A review and update
27. Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in hypertension
28. Vascular heat shock protein expression in response to stress
29. Variation in expression of hsp27 messenger ribonucleic acid during the cycle of the seminiferous epithelium and co-localization of hsp27 and microfilaments in sertoli cells of the rat
30. The phosphorylation events associated with cyclic nucleotide-dependent inhibition of smooth muscle contraction
31. Nitric oxide is an autocrine feedback regulator of vascular smooth muscle contraction