Essential role of L-arginine uptake and protein tyrosine kinase activity for NO-dependent vasorelaxation induced by stretch, isometric tension and cyclic AMP in rat pulmonary arteries

British Journal of Pharmacology

Volumn 131, Issue 7, 2000, Pages 1475-1481

  Hucks, David ^a   Khan, Nayeem M ^a   Ward, Jeremy P T ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Arginine paradox; Cyclic AMP; Isometric tension; L arginine; Nitric oxide; Nitric oxide synthase; Passive stretch; Protein tyrosine kinase; Pulmonary artery

Indexed keywords

ARGININE; CALCIUM; CYCLIC AMP; ERBSTATIN; GENISTEIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROSTAGLANDIN F2 ALPHA; PROTEIN TYROSINE KINASE; TYRPHOSTIN;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; RAT; VASODILATATION;

ACETYLCHOLINE; ANIMALS; ARGININE; CYCLIC AMP; DINOPROST; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HYDROQUINONES; ISOMETRIC CONTRACTION; LYSINE; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PROTEIN-TYROSINE KINASES; PULMONARY ARTERY; RATS; RATS, WISTAR; STRESS, MECHANICAL; THIONUCLEOTIDES; TYRPHOSTINS; VASODILATION; VASODILATOR AGENTS;

EID: 0033637464     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703718     Document Type: Article

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