The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice

Experimental Cell Research

Volumn 312, Issue 1, 2006, Pages 16-26

  Plowman, Sarah J ^a,d   Arends, Mark J ^b   Brownstein, David G ^c   Luo, Feijun ^b   Devenney, Paul S ^a,e   Rose, Lorraine ^a   Ritchie, Ann Marie ^a   Berry, Rachel L ^a,e   Harrison, David J ^a   Hooper, Martin L ^a   Patek, Charles E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF QUEENSLAND   (Australia)

^e WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Alternative splicing; Apoptosis; Differentiation; Intestine; Isoform; K ras; Proliferation; Stem cell

Indexed keywords

ETOPOSIDE; K RAS PROTEIN; RAS PROTEIN;

AGING; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INCIDENCE; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG INHIBITION; EMBRYONIC STEM CELL; LIFESPAN; MOLECULAR BIOLOGY; MOUSE; MUTATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REDUCTION; SMALL INTESTINE;

ANIMALIA;

EID: 27944488016     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2005.10.004     Document Type: Article

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