Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence

American Journal of Pathology

Volumn 156, Issue 2, 2000, Pages 555-566

  Walch, Axel K ^a   Zitzelsberger, Horst F ^a,b   Bruch, Jochen ^a   Keller, Gisela ^c   Angermeier, Daniela ^a   Aubele, Michaela M ^a   Mueller, James ^d   Stein, Hubert ^d   Braselmann, Herbert ^a   Siewert, Jörg R ^d   Höfler, Heinz ^c   Werner, Martin ^c  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DYSPLASIA; ESOPHAGUS CARCINOMA; ESOPHAGUS DISEASE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; MALE; METAPLASIA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0033899382     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64760-8     Document Type: Article

References (51)

1. Barrett's esophagus
2. The molecular pathology of Barrett's esophagus
3. Rising incidence of adenocarcinoma of the esophagus and gastric cardia
4. Epidemiology and molecular biology of Barrett's adenocarcinoma
5. Distribution of dysplasias and early invasive carcinoma in Barrett's esophagus
6. Observer variation in the diagnosis of dysplasia in Barrett's esophagus
7. Barrett's esophagus with high-grade dysplasia: An indication for esophagectomy?
8. The management of high grade dysplasia and early cancer in Barrett's esophagus: A multidisciplinary problem
9. Cytogenetic analysis of Barrett's mucosa and adenocarcinoma of the distal esophagus and cardia
10. Interphase cytogenetics esophageal adenocarcinoma and precursor lesions
11. Comparative genomic hybridization of esophageal and gastroesophageal adenocarcinomas shows consensus areas of DNA gain and loss
12. Consistent genetic alterations in xenografts of proximal stomach and gastroesophageal junction adenocarcinomas
13. Comparative genomic hybridization of cancer of the gastroesophageal junction: Deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas
14. Genetic alterations in Barrett esophagus, and adenocarcinomas of the esophagus, and esophagogastric junction region
15. Barrett's Oesophagus: Microsatellite analysis provides evidence to support the proposed metaplasia-dysplasia-carcinoma sequence
16. FHIT gene alterations in esophageal cancer and ulcerative colitis (UC)
17. Frequent deletions of FHIT and FRA3B in Barrett's metaplasia and esophageal adenocarcinomas
18. Allelic loss and mutational analysis of the DPC4 gene in esophageal adenocarcinoma
19. Classification of malignant tumors
20. Degenerate oligonucleotide-primed PCR: General amplification of target DNA by a single degenerate primer
21. Recurrent chromosomal imbalances detected in biopsy material from oral premalignant and malignant lesions by combined tissue microdissection, universal DNA amplification, and comparative genomic hybridization
22. Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia
23. Typical, and atypical carcinoid tumors of the lung are characterized by 11q deletions as detected by comparative genomic hybridization
24. Mapping of chromosomal imbalances in pancreatic carcinoma by comparative genomic hybridization
25. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors
26. Comparative genomic hybridization
27. 20q13.2 Amplification in intraductal hyperplasia adjacent to in situ, and invasive ductal carcinoma of the breast
28. Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays
29. Mapping of chromosomal imbalances in gastric adenocarcinoma revealed amplified protooncogenes MYCN, MET, WNT2, and ERBB2
30. MYC oncogenes and human neoplastic disease
31. Detection of amplified DNA sequences in gastric cancers by a DNA renaturation method in gel
32. Isolation of an amplified DNA sequence in stomach cancer
33. Immunohistochemical detection of K-sam protein in stomach cancer
34. Amplification of c-myc, K-sam, and c-met in gastric cancers: Detection by fluorescence in situ hybridization
35. Amplification and over-expression of the EGFR and erbB-2 genes in human esophageal adenocarcinomas
36. AIB1, a steroid receptor coactivator amplified in breast, and ovarian cancer
37. A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines
38. Allelic loss of 9p21 and mutation of the CDKN2/p16 gene develop as early lesions during neoplastic progression in Barrett's esophagus
39. Allelic loss and mutational analysis of the DPC4 gene in esophageal adenocarcinoma
40. Mapping of genetic deletions on the long arm of chromosome 4 in human esophageal adenocarcinomas
41. Evolution of neoplastic cell lineages in Barrett oesophagus
42. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
43. Optimization of comparative genomic hybridization using fluoro-chrome conjugated to dCTP and dUTP nucleotides
44. Barrett's esophagus: Metaplastic cells with loss of heterozygosity at the APC gene locus are clonal precursors to invasive adenocarcinoma
45. Clonal analysis of a case of multifocal oesophageal (Barrett's) adenocarcinoma by comparative genomic hybridization
46. The clonal evolution of tumor cell populations
47. Oesophageal cancer is an uncommon cause of death in patients with Barrett's oesophagus
48. Clonal genetic alterations in the lungs of current and former smokers
49. Gastric precancerous process in a high risk population: Cohort follow-up
50. Low incidence of significant dysplasia in a successful endoscopic surveillance program of patients with ulcerative colitis