Sarcopenia of male aging

Endocrinology and Metabolism Clinics of North America

Volumn 34, Issue 4, 2005, Pages 833-852

  Chow, Lisa S ^a   Nair, K Sreekumaran ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TESTOSTERONE; TESTOSTERONE CIPIONATE; TESTOSTERONE ENANTATE;

AGING; ANDROGEN DEFICIENCY; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DISEASE ASSOCIATION; DISEASE COURSE; DUAL ENERGY X RAY ABSORPTIOMETRY; EXERCISE; HUMAN; HYPOGONADISM; MUSCLE ATROPHY; MUSCLE MASS; MUSCLE METABOLISM; MUSCLE STRENGTH; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL ACTIVITY; PRIORITY JOURNAL; REVIEW;

AGED; AGING; HUMANS; MALE; MUSCULAR ATROPHY;

EID: 27944456033     PISSN: 08898529     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ecl.2005.07.007     Document Type: Review

References (77)

1. M.E. Tinetti, and M. Speechley Prevention of falls among the elderly N Engl J Med 320 16 1989 1055 1059
2. L. Wolfson, J. Judge, and R. Whipple Strength is a major factor in balance, gait, and the occurrence of falls J Gerontol A Biol Sci Med Sci 50 1995 64 67
3. L.A. Herndon, P.J. Schmeissner, and J.M. Dudaronek Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans Nature 419 6909 2002 808 814
4. G.B. Forbes, and J.C. Reina Adult lean body mass declines with age: some longitudinal observations Metabolism 19 9 1970 653 663
5. J.J. Kehayias, M.A. Fiatarone, and H. Zhuang Total body potassium and body fat: relevance to aging Am J Clin Nutr 66 4 1997 904 910
6. K.R. Short, J.L. Vittone, and M.L. Bigelow Age and aerobic exercise training effects on whole body and muscle protein metabolism Am J Physiol Endocrinol Metab 286 1 2004 E92 E101
7. L.J. Melton 3rd, S. Khosla, and B.L. Riggs Epidemiology of sarcopenia Mayo Clin Proc 75 2000 S10 S12
8. P. Szulc, F. Duboeuf, and F. Marchand Hormonal and lifestyle determinants of appendicular skeletal muscle mass in men: the MINOS study Am J Clin Nutr 80 2 2004 496 503
9. D.N. Proctor, P.C. O'Brien, and E.J. Atkinson Comparison of techniques to estimate total body skeletal muscle mass in people of different age groups Am J Physiol 277 1999 E489 E495
10. J. Lexell, C.C. Taylor, and M. Sjostrom What is the cause of the ageing atrophy? Total number, size, and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men J Neurol Sci 84 1988 275 294
11. J. Lexell, K. Henriksson-Larsen, and B. Winblad Distribution of different fiber types in human skeletal muscles: effects of aging studied in whole muscle cross sections Muscle Nerve 6 8 1983 588 595
12. R.S. Lindle, E.J. Metter, and N.A. Lynch Age and gender comparisons of muscle strength in 654 women and men aged 20-93 yr J Appl Physiol 83 5 1997 1581 1587
13. N.A. Lynch, E.J. Metter, and R.S. Lindle Muscle quality. I. Age-associated differences between arm and leg muscle groups J Appl Physiol 86 1 1999 188 194
14. D.A. Kallman, C.C. Plato, and J.D. Tobin The role of muscle loss in the age-related decline of grip strength: cross-sectional and longitudinal perspectives J Gerontol 45 3 1990 M82 M88
15. V.A. Hughes, W.R. Frontera, and M. Wood Longitudinal muscle strength changes in older adults: influence of muscle mass, physical activity, and health J Gerontol A Biol Sci Med Sci 56 5 2001 B209 B217
16. A. Aniansson, M. Hedberg, and G.B. Henning Muscle morphology, enzymatic activity, and muscle strength in elderly men: a follow-up study Muscle Nerve 9 7 1986 585 591
17. T. Rantanen, K. Masaki, and D. Foley Grip strength changes over 27 yr in Japanese American men J Appl Physiol 85 6 1998 2047 2053
18. W.R. Frontera, V.A. Hughes, and R.A. Fielding Aging of skeletal muscle: a 12-yr longitudinal study J Appl Physiol 88 4 2000 1321 1326
19. E.J. Metter, N. Lynch, and R. Conwit Muscle quality and age: cross-sectional and longitudinal comparisons J Gerontol A Biol Sci Med Sci 54 5 1999 B207 B218
20. W.R. Frontera, V.A. Hughes, and K.J. Lutz A cross-sectional study of muscle strength and mass in 45- to 78-yr-old men and women J Appl Physiol 71 2 1991 644 650
21. W.R. Frontera, D. Suh, and L.S. Krivickas Skeletal muscle fiber quality in older men and women Am J Physiol Cell Physiol 279 3 2000 C611 C618
22. R.L. Reed, L. Pearlmutter, and K. Yochum The relationship between muscle mass and muscle strength in the elderly J Am Geriatr Soc 39 6 1991 555 561
23. L. Larsson, X. Li, and W.R. Frontera Effects of aging on shortening velocity and myosin isoform composition in single human skeletal muscle cells Am J Physiol 272 1997 C638 C649
24. T.J. Overend, D.A. Cunningham, and D.H. Paterson Thigh composition in young and elderly men determined by computed tomography Clin Physiol 12 6 1992 629 640
25. R.J. Balice-Gordon Age-related changes in neuromuscular innervation Muscle Nerve Suppl 5 1997 S83 S87
26. A.R. Coggan, R.J. Spina, and D.S. King Histochemical and enzymatic comparison of the gastrocnemius muscle of young and elderly men and women J Gerontol 47 3 1992 B71 B76
27. H. Klitgaard, M. Mantoni, and S. Schiaffino Function, morphology and protein expression of ageing skeletal muscle: a cross-sectional study of elderly men with different training backgrounds Acta Physiol Scand 140 1 1990 41 54
28. P. Balagopal, J.C. Schimke, and P. Ades Age effect on transcript levels and synthesis rate of muscle MHC and response to resistance exercise Am J Physiol Endocrinol Metab 280 2 2001 E203 E208
29. P. Balagopal, O.E. Rooyackers, and D.B. Adey Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans Am J Physiol 273 1997 E790 E800
30. O.E. Rooyackers, D.B. Adey, and P.A. Ades Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle Proc Natl Acad Sci USA 93 26 1996 15364 15369
31. I. Trounce, E. Byrne, and S. Marzuki Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing Lancet 1 8639 1989 637 639
32. K.R. Short, and K.S. Nair Mechanisms of sarcopenia of aging J Endocrinol Invest 22 Suppl 5 1999 95 105
33. K.S. Nair Muscle protein turnover: methodological issues and the effect of aging J Gerontol A Biol Sci Med Sci 50 1995 107 112
34. K.S. Nair, D. Halliday, and R.C. Griggs Leucine incorporation into mixed skeletal muscle protein in humans Am J Physiol 254 1988 E208 E213
35. K.D. Tipton, and R.R. Wolfe Exercise, protein metabolism, and muscle growth Int J Sport Nutr Exerc Metab 11 1 2001 109 132
36. K.E. Yarasheski, J.J. Zachwieja, and D.M. Bier Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women Am J Physiol 265 1993 E210 E214
37. S. Welle, C. Thornton, and R. Jozefowicz Myofibrillar protein synthesis in young and old men Am J Physiol 264 1993 E693 E698
38. K.R. Short, J.L. Vittone, and M.L. Bigelow Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity Diabetes 52 8 2003 1888 1896
39. E. Volpi, M. Sheffield-Moore, and B.B. Rasmussen Basal muscle amino acid kinetics and protein synthesis in healthy young and older men JAMA 286 10 2001 1206 1212
40. K.E. Yarasheski, S. Welle, and K. Sreekumaran Nair Muscle protein synthesis in younger and older men JAMA 287 3 2002 317 318
41. D.W. Russ, and J.A. Kent-Braun Is skeletal muscle oxidative capacity decreased in old age? Sports Med 34 4 2004 221 229
42. S. Melov, J.M. Shoffner, and A. Kaufman Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle [erratum appears in Nucleic Acids Res 1995;23(23):4938] Nucleic Acids Res 23 20 1995 4122 4126
43. M.K. Shigenaga, T.M. Hagen, and B.N. Ames Oxidative damage and mitochondrial decay in aging Proc Natl Acad Sci USA 91 23 1994 10771 10778
44. R. Barazzoni, K.R. Short, and K.S. Nair Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart J Biol Chem 275 5 2000 3343 3347
45. L. DiPietro Physical activity in aging: changes in patterns and their relationship to health and function J Gerontol A Biol Sci Med Sci 56 2001 13 22
46. S.M. Harman, E.J. Metter, and J.D. Tobin Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging J Clin Endocrinol Metab 86 2 2001 724 731
47. A.W. van den Beld, F.H. de Jong, and D.E. Grobbee Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men J Clin Endocrinol Metab 85 9 2000 3276 3282
48. R.L. Ferrini, and E. Barrett-Connor Sex hormones and age: a cross-sectional study of testosterone and estradiol and their bioavailable fractions in community-dwelling men Am J Epidemiol 147 8 1998 750 754
49. B.F. Hurley, and J.M. Hagberg Optimizing health in older persons: aerobic or strength training? Exer Sport Sci Rev 26 1998 61 89
50. M.A. Rogers, and W.J. Evans Changes in skeletal muscle with aging: effects of exercise training Exer Sport Sci Rev 21 1993 65 102
51. C.N. Meredith, W.R. Frontera, and E.C. Fisher Peripheral effects of endurance training in young and old subjects J Appl Physiol 66 6 1989 2844 2849
52. D.L. Hasten, J. Pak-Loduca, and K.A. Obert Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78-84 and 23-32-yr-olds Am J Physiol Endocrinol Metab 278 4 2000 E620 E626
53. K.E. Yarasheski, J.J. Zachwieja, and J.A. Campbell Effect of growth hormone and resistance exercise on muscle growth and strength in older men Am J Physiol 268 2 Pt 1 1995 E268 E276
54. G. Biolo, S.P. Maggi, and B.D. Williams Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humans Am J Physiol 268 1995 E514 E520
55. D.C. Cumming, and S.R. Wall Nonsex hormone-binding globulin-bound testosterone as a marker for hyperandrogenism J Clin Endocrinol Metab 61 5 1985 873 876
56. A. Vermeulen, L. Verdonck, and J.M. Kaufman A critical evaluation of simple methods for the estimation of free testosterone in serum J Clin Endocrinol Metab 84 10 1999 3666 3672
57. A. Vermeulen, T. Stoica, and L. Verdonck The apparent free testosterone concentration, an index of androgenicity J Clin Endocrinol Metab 33 5 1971 759 767
58. The Endocrine Society. Summary from the 2nd Annual Andropause Consensus Meeting. Chevy Chase (MD): The Endocrine Society; 2001.
59. A.B. Araujo, A.B. O'Donnell, and D.J. Brambilla Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study J Clin Endocrinol Metab 89 12 2004 5920 5926
60. A.T. Kenyon, K. Knowlton, and I. Sandiford A comparative study of the metabolic effects of testosterone propionate in normal men and women and in eunuchoidism Endocrinology 26 1940 26 45
61. P.J. Snyder, H. Peachey, and J.A. Berlin Effects of testosterone replacement in hypogonadal men J Clin Endocrinol Metab 85 8 2000 2670 2677
62. S. Bhasin, T.W. Storer, and N. Berman Testosterone replacement increases fat-free mass and muscle size in hypogonadal men J Clin Endocrinol Metab 82 2 1997 407 413
63. S. Bhasin, T.W. Storer, and N. Berman The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men N Engl J Med 335 1 1996 1 7
64. L. Katznelson, J.S. Finkelstein, and D.A. Schoenfeld Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism J Clin Endocrinol Metab 81 12 1996 4358 4365
65. C. Wang, R.S. Swedloff, and A. Iranmanesh Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. Testosterone Gel Study Group J Clin Endocrinol Metab 85 8 2000 2839 2853
66. C. Wang, D.R. Eyre, and R. Clark Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men - a clinical research center study J Clin Endocrinol Metab 81 10 1996 3654 3662
67. I.G. Brodsky, P. Balagopal, and K.S. Nair Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men - a clinical research center study J Clin Endocrinol Metab 81 10 1996 3469 3475
68. G.B. Forbes The effect of anabolic steroids on lean body mass: the dose response curve Metabolism 34 6 1985 571 573
69. C. Wang, G. Cunningham, and A. Dobs Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men J Clin Endocrinol Metab 89 5 2004 2085 2098
70. J.S. Tenover Effects of testosterone supplementation in the aging male J Clin Endocrinol Metab 75 4 1992 1092 1098
71. A.A. Ferrando, K.D. Tipton, and D. Doyle Testosterone injection stimulates net protein synthesis but not tissue amino acid transport Am J Physiol 275 1998 E864 E871
72. R.J. Urban, Y.H. Bodenburg, and C. Gilkison Testosterone administration to elderly men increases skeletal muscle strength and protein synthesis Am J Physiol 269 1995 E820 E826
73. G.A. Wittert, I.M. Chapman, and M.T. Haren Oral testosterone supplementation increases muscle and decreases fat mass in healthy elderly males with low-normal gonadal status J Gerontol A Biol Sci Med Sci 58 7 2003 618 625
74. P.J. Snyder, H. Peachey, and P. Hannoush Effect of testosterone treatment on body composition and muscle strength in men over 65 years of age J Clin Endocrinol Metab 84 8 1999 2647 2653
75. J.E. Clague, F.C. Wu, and M.A. Horan Difficulties in measuring the effect of testosterone replacement therapy on muscle function in older men Int J Androl 22 4 1999 261 265
76. R. Sih, J.E. Morley, and F.E. Kaiser Testosterone replacement in older hypogonadal men: a 12-month randomized controlled trial J Clin Endocrinol Metab 82 6 1997 1661 1667
77. J.E. Morley, H.M. Perry 3rd, and F.E. Kaiser Effects of testosterone replacement therapy in old hypogonadal males: a preliminary study J Am Geriatr Soc 41 2 1993 149 152