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Volumn 286, Issue 1 49-1, 2004, Pages

Age and aerobic exercise training effects on whole body and muscle protein metabolism

Author keywords

Aging; Amino acid kinetics; Fractional synthesis rate; Leucine; Phenylalanine; Resting metabolic rate

Indexed keywords

LEUCINE; PHENYLALANINE;

EID: 0347417903     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00366.2003     Document Type: Article
Times cited : (375)

References (51)
  • 1
    • 0032088943 scopus 로고    scopus 로고
    • The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults
    • American College of Sports Medicine. The recommended quantity and quality of exercise for developing and maintaining cardiorespiratory and muscular fitness, and flexibility in healthy adults. Med Sci Sports Exerc 30: 975-991, 1998.
    • (1998) Med Sci Sports Exerc , vol.30 , pp. 975-991
  • 3
    • 0030707838 scopus 로고    scopus 로고
    • Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans
    • Balagopal P, Rooyackers OE, Adey DB, Ades PA, and Nair KS. Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol Endocrinol Metab 273: E790-E800, 1997.
    • (1997) Am J Physiol Endocrinol Metab , vol.273
    • Balagopal, P.1    Rooyackers, O.E.2    Adey, D.B.3    Ades, P.A.4    Nair, K.S.5
  • 4
    • 0034996561 scopus 로고    scopus 로고
    • Age effect on transcript levels and synthesis rate of MHC and response to resistance exercise
    • Balagopal P, Schimke JC, Ades P, Adey D, and Nair KS. Age effect on transcript levels and synthesis rate of MHC and response to resistance exercise. Am J Physiol Endocrinol Metab 280: E203-E208, 2001.
    • (2001) Am J Physiol Endocrinol Metab , vol.280
    • Balagopal, P.1    Schimke, J.C.2    Ades, P.3    Adey, D.4    Nair, K.S.5
  • 6
    • 0028796074 scopus 로고
    • Resting metabolic rate and protein turnover in apparently healthy elderly Gambian men
    • Benedek C, Berclaz PY, Jequier E, and Schutz Y. Resting metabolic rate and protein turnover in apparently healthy elderly Gambian men. Am J Physiol Endocrinol Metab 268: E1083-E1088, 1995.
    • (1995) Am J Physiol Endocrinol Metab , vol.268
    • Benedek, C.1    Berclaz, P.Y.2    Jequier, E.3    Schutz, Y.4
  • 7
    • 0030897107 scopus 로고    scopus 로고
    • Splanchnic and whole-body leucine kinetics in young and elderly men
    • Boirie Y, Gachon P, and Beaufrere B. Splanchnic and whole-body leucine kinetics in young and elderly men. Am J Clin Nutr 65: 489-495, 1997.
    • (1997) Am J Clin Nutr , vol.65 , pp. 489-495
    • Boirie, Y.1    Gachon, P.2    Beaufrere, B.3
  • 8
    • 0035092636 scopus 로고    scopus 로고
    • Differential insulin sensitivities of glucose, amino acid, and albumin metabolism in elderly men and women
    • Boirie Y, Gachon P, Cordat N, Ritz P, and Beaufrere B. Differential insulin sensitivities of glucose, amino acid, and albumin metabolism in elderly men and women. J Clin Endocrin Metab 86: 638-644, 2001.
    • (2001) J Clin Endocrin Metab , vol.86 , pp. 638-644
    • Boirie, Y.1    Gachon, P.2    Cordat, N.3    Ritz, P.4    Beaufrere, B.5
  • 9
    • 0025782887 scopus 로고
    • Molecular and cellular adaptation of muscle in response to exercise: Perspectives of various models
    • Booth FW. Molecular and cellular adaptation of muscle in response to exercise: perspectives of various models. Physiol Rev 71: 541-585, 1991.
    • (1991) Physiol Rev , vol.71 , pp. 541-585
    • Booth, F.W.1
  • 10
    • 0030015688 scopus 로고    scopus 로고
    • Evidence for a catabolic role of glucagon during an amino acid load
    • Charlton MR, Adey DB, and Nair KS. Evidence for a catabolic role of glucagon during an amino acid load. J Clin Invest 98: 90-99, 1996.
    • (1996) J Clin Invest , vol.98 , pp. 90-99
    • Charlton, M.R.1    Adey, D.B.2    Nair, K.S.3
  • 13
    • 0031471922 scopus 로고    scopus 로고
    • Critical assessment of methods used to measure protein synthesis in human subjects
    • Garlick PJ, McNurlan MA, and Caso G. Critical assessment of methods used to measure protein synthesis in human subjects. Yale J Biol Med 70: 65-76, 1997.
    • (1997) Yale J Biol Med , vol.70 , pp. 65-76
    • Garlick, P.J.1    McNurlan, M.A.2    Caso, G.3
  • 14
    • 0019158581 scopus 로고
    • Dynamic aspects of whole body glycine metabolism: Influence of protein intake in young adult and elderly males
    • Gersovitz M, Bier D, Matthews D, Udall J, Munro HN, and Young VR. Dynamic aspects of whole body glycine metabolism: influence of protein intake in young adult and elderly males. Metabolism 29: 1087-1094, 1980.
    • (1980) Metabolism , vol.29 , pp. 1087-1094
    • Gersovitz, M.1    Bier, D.2    Matthews, D.3    Udall, J.4    Munro, H.N.5    Young, V.R.6
  • 15
    • 0034001564 scopus 로고    scopus 로고
    • Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78-84 and 23-32 yr olds
    • Hasten DL, Pak-Loduca J, Obert KA, and Yarasheski KE. Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78-84 and 23-32 yr olds. Am J Physiol Endocrinol Metab 278: E620-E626, 2000.
    • (2000) Am J Physiol Endocrinol Metab , vol.278
    • Hasten, D.L.1    Pak-Loduca, J.2    Obert, K.A.3    Yarasheski, K.E.4
  • 16
    • 0030903117 scopus 로고    scopus 로고
    • Age and sex effects on energy expenditure
    • Klausen BS, Toubro S, and Astrup A. Age and sex effects on energy expenditure. Am J Clin Nutr 65: 895-907, 1996.
    • (1996) Am J Clin Nutr , vol.65 , pp. 895-907
    • Klausen, B.S.1    Toubro, S.2    Astrup, A.3
  • 17
    • 0034972611 scopus 로고    scopus 로고
    • Gender differences in leucine, but not lysine, kinetics
    • Lamont LS, McCullough AJ, and Kalhan SC. Gender differences in leucine, but not lysine, kinetics. J Appl Physiol 91: 357-362, 2001.
    • (2001) J Appl Physiol , vol.91 , pp. 357-362
    • Lamont, L.S.1    McCullough, A.J.2    Kalhan, S.C.3
  • 18
    • 0033951417 scopus 로고    scopus 로고
    • Measuring leg muscle and fat mass in humans: Comparison of CT and dual-energy X-ray absorptiometry
    • Levine JA, Abboud L, Barry M, Reed JE, Sheedy PF, and Jensen MD. Measuring leg muscle and fat mass in humans: comparison of CT and dual-energy X-ray absorptiometry. J Appl Physiol 88: 452-456, 2000.
    • (2000) J Appl Physiol , vol.88 , pp. 452-456
    • Levine, J.A.1    Abboud, L.2    Barry, M.3    Reed, J.E.4    Sheedy, P.F.5    Jensen, M.D.6
  • 20
    • 0031793982 scopus 로고    scopus 로고
    • Differential regulation of amino acid exchange and protein dynamics across splanchnic and skeletal muscle beds by insulin in healthy human subjects
    • Meek SE, Persson M, Ford GC, and Nair KS. Differential regulation of amino acid exchange and protein dynamics across splanchnic and skeletal muscle beds by insulin in healthy human subjects. Diabetes 47: 1824-1835, 1998.
    • (1998) Diabetes , vol.47 , pp. 1824-1835
    • Meek, S.E.1    Persson, M.2    Ford, G.C.3    Nair, K.S.4
  • 23
    • 0034065780 scopus 로고    scopus 로고
    • Distribution of protein turnover changes with age in humans as assessed by whole-body magnetic resonance image analysis to quantify tissue volumes
    • Morais JA, Ross R, Gougeon R, Pencharz PB, Jones PHJ, and Marliss EB. Distribution of protein turnover changes with age in humans as assessed by whole-body magnetic resonance image analysis to quantify tissue volumes. J Nutr 130: 784-791, 2000.
    • (2000) J Nutr , vol.130 , pp. 784-791
    • Morais, J.A.1    Ross, R.2    Gougeon, R.3    Pencharz, P.B.4    Jones, P.H.J.5    Marliss, E.B.6
  • 25
    • 0029073033 scopus 로고
    • Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients
    • Nair KS, Ford GC, Ekberg K, Fernqvist-Forbes E, and Wahren J. Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients. J Clin Invest 95: 2926-2937, 1995.
    • (1995) J Clin Invest , vol.95 , pp. 2926-2937
    • Nair, K.S.1    Ford, G.C.2    Ekberg, K.3    Fernqvist-Forbes, E.4    Wahren, J.5
  • 26
  • 28
    • 0028819528 scopus 로고
    • Effect of variable protein intake on whole-body protein turnover in young men and women
    • Pannemans DLE, Halliday D, Westerterp KR, and Kester ADM. Effect of variable protein intake on whole-body protein turnover in young men and women. Am J Clin Nutr 61: 69-74, 1995.
    • (1995) Am J Clin Nutr , vol.61 , pp. 69-74
    • Pannemans, D.L.E.1    Halliday, D.2    Westerterp, K.R.3    Kester, A.D.M.4
  • 29
    • 0031736360 scopus 로고    scopus 로고
    • Is there evidence for an age-related reduction in metabolic rate?
    • Piers LS, Soares MJ, McCormack LM, and O'Dea K. Is there evidence for an age-related reduction in metabolic rate? J Appl Physiol 85: 2196-2204, 1998.
    • (1998) J Appl Physiol , vol.85 , pp. 2196-2204
    • Piers, L.S.1    Soares, M.J.2    McCormack, L.M.3    O'Dea, K.4
  • 32
    • 0030451773 scopus 로고    scopus 로고
    • Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle
    • Rooyackers OE, Adey DB, Ades PA, and Nair KS. Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc Natl Acad Sci USA 93: 15364-15369, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15364-15369
    • Rooyackers, O.E.1    Adey, D.B.2    Ades, P.A.3    Nair, K.S.4
  • 33
    • 0039997846 scopus 로고
    • Studies of protein retention and turnover using nitrogen-15 as a tag
    • Sharp CS, Lassen S, Shankman S, Hazlet JW, and Keduris MS. Studies of protein retention and turnover using nitrogen-15 as a tag. J Nutr 63: 155-160, 1957.
    • (1957) J Nutr , vol.63 , pp. 155-160
    • Sharp, C.S.1    Lassen, S.2    Shankman, S.3    Hazlet, J.W.4    Keduris, M.S.5
  • 34
    • 0032609109 scopus 로고    scopus 로고
    • Mechanisms of sarcopenia of aging
    • Short KR and Nair KS. Mechanisms of sarcopenia of aging. J Endocrinol Invest 22: 95-105, 1999.
    • (1999) J Endocrinol Invest , vol.22 , pp. 95-105
    • Short, K.R.1    Nair, K.S.2
  • 36
    • 0031888710 scopus 로고    scopus 로고
    • Exercise-induced changes in protein metabolism
    • Tipton KD and Wolfe RR. Exercise-induced changes in protein metabolism. Acta Physiol Scand 162: 377-387, 1998.
    • (1998) Acta Physiol Scand , vol.162 , pp. 377-387
    • Tipton, K.D.1    Wolfe, R.R.2
  • 40
    • 0034485454 scopus 로고    scopus 로고
    • The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly
    • Volpi E, Mittendorfer B, Rasmussen BB, and Wolfe RR. The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly. J Clin Endocrin Metab 2000: 4481-4490, 2001.
    • (2001) J Clin Endocrin Metab , vol.2000 , pp. 4481-4490
    • Volpi, E.1    Mittendorfer, B.2    Rasmussen, B.B.3    Wolfe, R.R.4
  • 41
    • 0032835655 scopus 로고    scopus 로고
    • Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction
    • Volpi E, Mittendorfer B, Wolf SE, and Wolfe RR. Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction. Am J Physiol Endocrinol Metab 277: E513-E520, 1999.
    • (1999) Am J Physiol Endocrinol Metab , vol.277
    • Volpi, E.1    Mittendorfer, B.2    Wolf, S.E.3    Wolfe, R.R.4
  • 42
    • 0347323275 scopus 로고    scopus 로고
    • Muscle protein synthesis in younger and older men
    • Volpi E, Rasmussen B, Sheffield-Moore M, and Wolfe RR. Muscle protein synthesis in younger and older men (Reply to Letter). JAMA 287: 318, 2002.
    • (2002) JAMA , vol.287 , pp. 318
    • Volpi, E.1    Rasmussen, B.2    Sheffield-Moore, M.3    Wolfe, R.R.4
  • 43
    • 0035850407 scopus 로고    scopus 로고
    • Basal muscle amino acid kinetics and protein synthesis in healthy young and older men
    • Volpi E, Sheffield-Moore M, Rasmussen B, and Wolfe RR. Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA 286: 1206-1212, 2001.
    • (2001) JAMA , vol.286 , pp. 1206-1212
    • Volpi, E.1    Sheffield-Moore, M.2    Rasmussen, B.3    Wolfe, R.R.4
  • 44
    • 0025292876 scopus 로고
    • Relationship of resting metabolic rate to body composition and protein turnover
    • Welle S and Nair KS. Relationship of resting metabolic rate to body composition and protein turnover. Am J Physiol Endocrinol Metab 258: E990-E998, 1990.
    • (1990) Am J Physiol Endocrinol Metab , vol.258
    • Welle, S.1    Nair, K.S.2
  • 46
    • 0028045582 scopus 로고
    • Postprandial myofibrillar and whole body protein synthesis in young and old human subjects
    • Welle S, Thornton C, Statt M, and McHenry B. Postprandial myofibrillar and whole body protein synthesis in young and old human subjects. Am J Physiol Endocrinol Metab 267: E599-E604, 1994.
    • (1994) Am J Physiol Endocrinol Metab , vol.267
    • Welle, S.1    Thornton, C.2    Statt, M.3    McHenry, B.4
  • 48
    • 0037116656 scopus 로고    scopus 로고
    • Muscle protein synthesis in younger and older men
    • Yarasheski KE, Welle S, and Nair KS. Muscle protein synthesis in younger and older men (Letter). JAMA 287: 317-318, 2002.
    • (2002) JAMA , vol.287 , pp. 317-318
    • Yarasheski, K.E.1    Welle, S.2    Nair, K.S.3
  • 49
    • 0027202154 scopus 로고
    • Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women
    • Yarasheski KE, Zachwieja JJ, and Bier DM. Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women. Am J Physiol Endocrinol Metab 265: E210-E214, 1993.
    • (1993) Am J Physiol Endocrinol Metab , vol.265
    • Yarasheski, K.E.1    Zachwieja, J.J.2    Bier, D.M.3
  • 51
    • 0016855154 scopus 로고
    • Total human body protein synthesis in relation to protein requirements at various ages
    • Young VR, Steffee WP, Pencharz PB, Winterer JC, and Scrimshaw NS. Total human body protein synthesis in relation to protein requirements at various ages. Nature 253: 192-193, 1975.
    • (1975) Nature , vol.253 , pp. 192-193
    • Young, V.R.1    Steffee, W.P.2    Pencharz, P.B.3    Winterer, J.C.4    Scrimshaw, N.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.