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Nielsen LPC, Stevenson CP, Blackmond DG, Jacobsen EN: Mechanistic investigation leads to a synthetic improvement in the hydrolytic kinetic resolution of terminal epoxides. J Am Chem Soc (2004) 126(5):1360-1362.
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Gigante L, Lunghi A, Martinelli S, Cardillo P, Picello L, Bortolaso R, Galvagni M, Rota R: Calorimetric approach and simulation for scaleup of a Friedel-Crafts reaction. Org Proc Res Dev (2003) 7(6):1079-1082. Discusses a kinetic study using reaction calorimetry and commercially available software.
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54
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Mechanistic insights into anomalous kinetic behavior in the hydrogenation of a substituted nitrobenzene
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LeBars J, Dini S, Hawkins JM, Blackmond DG: Mechanistic insights into anomalous kinetic behavior in the hydrogenation of a substituted nitrobenzene. Adv Synth Catal (2004) 346(8):943-946. Explains anomalous behavior by postulating that Rideal and Langmuir-Hinshelwood mechanisms are dominant during different phases of the reaction.
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Adv Synth Catal
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Furusjo E, Danielsson L-G: Target testing procedure for determining chemical kinetics from spectroscopic data with absorption shifts and baseline drift. Chemometr Intell Lab Syst (2000) 50(1):63-73. Introduces a target testing method for estimation of kinetic parameters from spectroscopic data in the presence of absorption peak shifts or baseline drift.
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Furusjo E, Svensson O, Danielsson L-G: Estimation of kinetic parameters from non-isothermal batch experiments monitored by in situ vibrational spectroscopy. Chemometr Intell Lab Syst (2003) 66(1):1-14. Discusses the application of the target testing method for estimation of kinetic parameters from spectroscopic data, with several examples.
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Chemometr Intell Lab Syst
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Pintar A, Malacea R, Pinel C, Fogassy G, Besson M: In situ monitoring of catalytic three-phase enantioselective hydrogenation using FTIR/ATR spectroscopy. Appl Catal A Gen (2004) 264(1):1-12. In situ FTIR was used to obtain a mechanistic insight into Pd/C catalyzed enantioselective hydrogenation of prochiral, exocyclic α,β-unsaturated ketones.
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Appl Catal A Gen
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Lobben PC, Leung SS-W, Tummala S: Integrated approach to the development and understanding of the borane reduction of a carboxylic acid. Org Proc Res Dev (2004) 8(6):1072-1075. Provides an example of the use of the integrated approach coupled with off-gas measurement to elucidate the kinetic parameters of a five-step mechanism.
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Org Proc Res Dev
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Zogg A, Fischer U, Hungerbuehler K: Identification of kinetic and thermodynamic reaction parameters from online calorimetric and IR-ATR data using a new combined evaluation algorithm. Chem Eng Sci (2004) 59(24):5795-5806. Provides an example of the application of the integrated approach and discusses potential pitfalls in relying on data from a single kinetic tool for a kinetic study.
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