Topiramate prevents excitotoxic damage in the newborn rodent brain

Neurobiology of Disease

Volumn 20, Issue 3, 2005, Pages 837-848

  Sfaello, Ignacio ^a,b   Baud, Olivier ^a   Arzimanoglou, Alexis ^a   Gressens, Pierre ^a  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b UNIVERSIDAD CATÓLICA DE CÓRDOBA   (Argentina)

Author keywords

Antiepileptic drugs; Cerebral Palsy; Neuroprotection

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTICONVULSIVE AGENT; CARBAMAZEPINE; DIAZEPAM; DIZOCILPINE; FORSKOLIN; IBOTENIC ACID; LONG ACTING DRUG; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; PHENYTOIN; PROTEIN KINASE C INHIBITOR; TOPIRAMATE; WORTMANNIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTOSIS; BRAIN CORTEX; BRAIN INJURY; CELL ACTIVATION; CELL SURVIVAL; CEREBRAL PALSY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; EXCITOTOXICITY; FEMALE; MALE; MICROGLIA; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; PERINATAL MORBIDITY; PRIORITY JOURNAL; RAT; RODENT; SAFETY; SEIZURE; WHITE MATTER;

ALANINE; ANIMALS; ANIMALS, NEWBORN; BRAIN; CEREBRAL PALSY; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; FRUCTOSE; GLUTAMIC ACID; HUMANS; HYPOXIA, BRAIN; IBOTENIC ACID; INFANT, NEWBORN; LEUKOMALACIA, PERIVENTRICULAR; MALE; MICE; NEUROPROTECTIVE AGENTS; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME;

EID: 27744597909     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.05.019     Document Type: Article

References (53)

1. L. Acarin, B. Gonzalez, J. Hidalgo, A.J. Castro, and B. Castellano Primary cortical glial reaction versus secondary thalamic glial response in the excitotoxically injured young brain: astroglial response and metallothionein expression Neuroscience 92 1999 827 839
2. J.D. Barks, and F.S. Silverstein Excitatory amino acids contribute to the pathogenesis of perinatal hypoxic-ischemic brain injury Brain Pathol. 2 1992 235 243
3. B.H. Cha, D.C. Silveira, X. Liu, Y. Hu, and G.L. Holmes Effect of topiramate following recurrent and prolonged seizures during early development Epilepsy Res. 51 2002 217 232
4. G. Coppola, G. Caliendo, M.M. Terracciano, S. Buono, L. Pellegrino, and A. Pascotto Topiramate in refractory partial-onset seizures in children, adolescents and young adults: a multicentric open trial Epilepsy Res. 43 2001 255 260
5. G. Coppola, G. Caliendo, P. Veggiotti, A. Romeo, G. Tortorella, P. De Marco, and A. Pascotto Topiramate as add-on drug in children, adolescents and young adults with Lennox-Gastaut syndrome: an Italian multicentric study Epilepsy Res. 51 2002 147 153
6. G. Coppola, G. Capovilla, A. Montagnini, A. Romeo, M. Spano, G. Tortorella, P. Veggiotti, M. Viri, and A. Pascotto Topiramate as add-on drug in severe myoclonic epilepsy in infancy: an Italian multicenter open trial Epilepsy Res. 49 2002 45 48
7. J.H. Cross Topiramate monotherapy for childhood absence seizures: an open label pilot study Seizure 11 2002 406 410
8. M.A. Dommergues, J. Patkai, J.C. Renauld, P. Evrard, and P. Gressens Proinflammatory cytokines and interleukin-9 exacerbate excitotoxic lesions of the newborn murine neopallium Ann. Neurol. 47 2000 54 63
9. C.W. Dunnett New tables for multiple comparaisons with a control Biometrics 1964 482 491
10. H.L. Edmonds Jr., Y.D. Jiang, P.Y. Zhang, and R. Shank Topiramate as a neuroprotectant in a rat model of global ischemia-induced neurodegeneration Life Sci. 69 2001 2265 2277
11. R.D. Elterman, T.A. Glauser, E. Wyllie, R. Reife, S.C. Wu, and G. Pledger A double-blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children. Topiramate YP Study Group Neurology 52 1999 1338 1344
12. P.L. Follett, P.A. Rosenberg, J.J. Volpe, and F.E. Jensen NBQX attenuates excitotoxic injury in developing white matter J. Neurosci. 20 2000 9235 9241
13. P.L. Follett, W. Deng, W. Dai, D.M. Talos, L.J. Massillon, P.A. Rosenberg, J.J. Volpe, and F.E. Jensen Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate J. Neurosci. 24 2004 4412 4420
14. A. Furuta, and L.J. Martin Laminar segregation of the cortical plate during corticogenesis is accompanied by changes in glutamate receptor expression J. Neurobiol. 39 1999 67 80
15. J.W. Gibbs III, S. Sombati, R.J. DeLorenzo, and D.A. Coulter Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons Epilepsia 41 Suppl. 1 2000 S10 S16
16. T.A. Glauser, M.V. Miles, P. Tang, P. Clark, K. McGee, and D.R. Doose Topiramate pharmacokinetics in infants Epilepsia 40 1999 788 791
17. C. Glier, M. Dzietko, P. Bittigau, B. Jarosz, E. Korobowicz, and C. Ikonomidou Therapeutic doses of topiramate are not toxic to the developing rat brain Exp. Neurol. 187 2004 403 409
18. P. Gressens, S. Marret, J.M. Hill, D.E. Brenneman, I. Gozes, M. Fridkin, and P. Evrard Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain J. Clin. Invest. 100 1997 390 397
19. P. Gressens, S. Marret, J.L. Martin, A. Laquerriere, A. Lombet, and P. Evrard Regulation of neuroprotective action of vasoactive intestinal peptide in the murine developing brain by protein kinase C and mitogen-activated protein kinase cascades: in vivo and in vitro studies J. Neurochem. 70 1998 2574 2584
20. D.S. Gryder, and M.A. Rogawski Selective antagonism of GluR5 kainate-receptor-mediated synaptic currents by topiramate in rat basolateral amygdala neurons J. Neurosci. 23 2003 7069 7074
21. A.J. Gunn, P.D. Gluckman, and T.R. Gunn Selective head cooling in newborn infants after perinatal asphyxia: a safety study Pediatrics 102 1998 885 892
22. Y. Hagino, Y. Kariura, Y. Manago, T. Amano, B. Wang, M. Sekiguchi, K. Nishikawa, S. Aoki, K. Wada, and M. Noda Heterogeneity and potentiation of AMPA type of glutamate receptors in rat cultured microglia Glia 47 2004 68 77
23. I. Husson, B. Mesples, P. Bac, J. Vamecq, P. Evrard, and P. Gressens Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge Ann. Neurol. 51 2002 82 92
24. C. Ikonomidou, F. Bosch, M. Miksa, P. Bittigau, J. Vockler, K. Dikranian, T.I. Tenkova, V. Stefovska, L. Turski, and J.W. Olney Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain Science 283 1999 70 74
25. G.M. Innocenti, and P. Berbel Analysis of an experimental cortical network: I. Architectonics of visual areas 17 and 18 after neonatal injections of ibotenic acid; similarities with human microgyria J. Neural Transpl. Plast. 2 1991 1 28
26. S.H. Khan, S.L. Wright, A. Banigesh, H. Miyashita, K. Todd, S.J. Hemmings, T. Wishart, and A. Shuaib Antiischemic effects of topiramate in a transient global forebrain ischemia model: a neurochemical, histological, and behavioral evaluation Neurochem. Res. 28 2003 1235 1239
27. S. Koh, and F.E. Jensen Topiramate blocks perinatal hypoxia-induced seizures in rat pups Ann. Neurol. 50 2001 366 372
28. V. Laudenbach, G. Calo, R. Guerrini, G. Lamboley, J.F. Benoist, P. Evrard, and P. Gressens Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain J. Clin. Invest. 107 2001 457 466
29. S.R. Lee, S.P. Kim, and J.E. Kim Protective effect of topiramate against hippocampal neuronal damage after global ischemia in the gerbils Neurosci. Lett. 281 2000 183 186
30. M.I. Levene, N.A. Gibson, A.C. Fenton, E. Papathoma, and D. Barnett The use of a calcium-channel blocker, nicardipine, for severely asphyxiated newborn infants Dev. Med. Child Neurol. 32 1990 567 574
31. M. Levene, M. Blennow, A. Whitelaw, E. Hanko, V. Fellman, and R. Hartley Acute effects of two different doses of magnesium sulphate in infants with birth asphyxia Arch. Dis. Child., Fetal Neonatal Ed. 73 1995 F174 F177
32. Y. Liu, J.D. Barks, G. Xu, and F.S. Silverstein Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats Stroke 35 2004 1460 1465
33. S. Marret, R. Mukendi, J.F. Gadisseux, P. Gressens, and P. Evrard Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions J. Neuropathol. Exp. Neurol. 54 1995 358 370
34. S. Marret, P. Gressens, and P. Evrard Arrest of neuronal migration by excitatory amino acids in hamster developing brain Proc. Natl. Acad. Sci. U. S. A. 93 1996 15463 15468
35. K. Matthias, F. Kirchhoff, G. Seifert, K. Huttmann, M. Matyash, H. Kettenmann, and C. Steinhauser Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus J. Neurosci. 23 2003 1750 1758
36. J.W. McDonald, F.S. Silverstein, and M.V. Johnston Neurotoxicity of N-methyl-d-aspartate is markedly enhanced in developing rat central nervous system Brain Res. 459 1988 200 203
37. K. Mohamed, R. Appleton, and L. Rosenbloom Efficacy and tolerability of topiramate in childhood and adolescent epilepsy: a clinical experience Seizure 9 2000 137 141
38. E.C. Moreland, D.A. Griesemer, and K.R. Holden Topiramate for intractable childhood epilepsy Seizure 8 1999 38 40
39. D.E. Pellegrini-Giampietro, M.V. Bennett, and R.S. Zukin Differential expression of three glutamate receptor genes in developing rat brain: an in situ hybridization study Proc. Natl. Acad. Sci. U. S. A. 88 1991 4157 4161
40. M.D. Privitera, M.J. Brodie, R.H. Mattson, D.W. Chadwick, W. Neto, and S. Wang Topiramate, carbamazepine and valproate monotherapy: double-blind comparison in newly diagnosed epilepsy Acta Neurol. Scand. 107 2003 165 175
41. C. Redecker, G. Hagemann, O.W. Witte, S. Marret, P. Evrard, and P. Gressens Long-term evolution of excitotoxic cortical dysgenesis induced in the developing rat brain Brain Res. Dev. Brain Res. 109 1998 109 113
42. F. Ritter, T.A. Glauser, R.D. Elterman, and E. Wyllie Effectiveness, tolerability, and safety of topiramate in children with partial-onset seizures. Topiramate YP Study Group Epilepsia 41 Suppl. 1 2000 S82 S85
43. P.A. Rosenberg, W. Dai, X.D. Gan, S. Ali, J. Fu, S.A. Back, R.M. Sanchez, M.M. Segal, P.L. Follett, F.E. Jensen, and J.J. Volpe Mature myelin basic protein-expressing oligodendrocytes are insensitive to kainate toxicity J. Neurosci. Res. 71 2003 237 245
44. R.C. Sachdeo, T.A. Glauser, F. Ritter, R. Reife, P. Lim, and G. Pledger A double-blind, randomized trial of topiramate in Lennox-Gastaut syndrome. Topiramate YL Study Group Neurology 52 1999 1882 1887
45. S. Skradski, and H.S. White Topiramate blocks kainate-evoked cobalt influx into cultured neurons Epilepsia 41 Suppl. 1 2000 S45 S47
46. B.G. Tabachnick, and L.S. Fidell Using Multivariate Statistics 3rd. ed. 1996 Harper Collins New York
47. S.L. Tahraoui, S. Marret, C. Bodenant, P. Leroux, M.A. Dommergues, P. Evrard, and P. Gressens Central role of microglia in neonatal excitotoxic lesions of the murine periventricular white matter Brain Pathol. 11 2001 56 71
48. S. Taverna, G. Sancini, M. Mantegazza, S. Franceschetti, and G. Avanzini Inhibition of transient and persistent Na+ current fractions by the new anticonvulsant topiramate J. Pharmacol. Exp. Ther. 288 1999 960 968
49. F. Van Bel, M. Shadid, R.M. Moison, C.A. Dorrepaal, J. Fontijn, L. Monteiro, B.M. Van De, and H.M. Berger Effect of allopurinol on postasphyxial free radical formation, cerebral hemodynamics, and electrical brain activity Pediatrics 101 1998 185 193
50. H.S. White, S.D. Brown, J.H. Woodhead, G.A. Skeen, and H.H. Wolf Topiramate modulates GABA-evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism Epilepsia 41 Suppl. 1 2000 S17 S20
51. Y. Yang, A. Shuaib, Q. Li, and M.M. Siddiqui Neuroprotection by delayed administration of topiramate in a rat model of middle cerebral artery embolization Brain Res. 804 1998 169 176
52. Y. Yang, Q. Li, and A. Shuaib Enhanced neuroprotection and reduced hemorrhagic incidence in focal cerebral ischemia of rat by low dose combination therapy of urokinase and topiramate Neuropharmacology 39 2000 881 888
53. X. Zhang, A.A. Velumian, O.T. Jones, and P.L. Carlen Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate Epilepsia 41 Suppl. 1 2000 S52 S60