Enhanced neuroprotection and reduced hemorrhagic incidence in focal cerebral ischemia of rat by low dose combination therapy of urokinase and topiramate

Neuropharmacology

Volumn 39, Issue 5, 2000, Pages 881-888

  Yang, Yi ^a   Li, Qiu ^a   Shuaib, Ashfaq ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cerebral hemorrhage; Combination therapy; Focal cerebral ischemia; Neuroprotective agent; Rat; Thrombolysis; Topiramate; Urokinase

Indexed keywords

TOPIRAMATE; UROKINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; BRAIN INFARCTION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; FIBRINOLYTIC THERAPY; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FRUCTOSE; INFARCTION, MIDDLE CEREBRAL ARTERY; INJECTIONS, INTRA-ARTERIAL; INJECTIONS, INTRAPERITONEAL; INTRACRANIAL THROMBOSIS; MALE; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; URINARY PLASMINOGEN ACTIVATOR;

EID: 0033972105     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(99)00248-8     Document Type: Article

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