Topiramate monotherapy for childhood absence seizures: An open label pilot study

Seizure

Volumn 11, Issue 6, 2002, Pages 406-410

  Cross, J Helen ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GREAT ORMOND STREET HOSPITAL   (United Kingdom)

Author keywords

Childhood absence seizures; EEG; Epilepsy; Pilot study; Topiramate

Indexed keywords

ANTICONVULSIVE AGENT; ETHOSUXIMIDE; TOPIRAMATE; VALPROIC ACID;

ABSENCE; AMBULATORY MONITORING; ARTICLE; AWARENESS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CONTROL; DRUG RESPONSE; DRUG TOLERABILITY; ELECTROENCEPHALOGRAM; FEMALE; HUMAN; MALE; MONOTHERAPY; MOOD; PILOT STUDY; PRIORITY JOURNAL; SIDE EFFECT; SPIKE WAVE;

EID: 0036747301     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1053/seiz.2001.0655     Document Type: Article

References (20)

1. Pearl, P. L. and Holmes, G. L. Absence seizures. In: Pediatric Epilepsy: Diagnosis and Therapy (Eds W. E. Dodson and J. M. Pellock). New York, Demos, 1993: pp. 157-170.
2. Berkovic, S. F. Childhood absence epilepsy and juvenile absence epilepsy. In: The Treatment of Epilepsy: Principles and Practice (Ed. E. Wyllie). Philadelphia, PA, Lea & Febiger, 1993: pp. 547-551.
3. Wirrell, E. C., Camfield, P. R., Camfield, C. S., Dooley, J. M. and Gordon, K. E. Accidental injury is a serious risk in children with typical absence epilepsy. Archives of Neurology 1996; 53: 929-932.
4. Pellock, J. M. Standard approach to antiepileptic drug treatment in the United States. Epilepsia 1994; 35 (Suppl. 4): S11-S18.
5. Pellock, J. M. and Pippenger, C. E. Adverse effects of antiepileptic drugs. In: Pediatric Epilepsy: Diagnosis and Therapy (Eds W. E. Dodson and J. M. Pellock). New York, Demos, 1993: pp. 253-264.
6. Schmidt, D. Adverse Effects of Antiepileptic Drugs. New York, Raven Press, 1982.
7. Osorio, I., Reed, R. C. and Peltzer, J. N. Refractory idiopathic absence status epilepticus: a probable paradoxical effect of phenytoin and carbamazepine. Epilepsia 2000; 41: 887-894.
8. Horn, C. S., Ater, S. B. and Hurst, D. L. Carbamazepine-exacerbated epilepsy in children and adolescents. Pediatric Neurology 1986; 2: 340-345.
9. Curry, W. J. and Kulling, D. L. Newer antiepileptic drugs: gabapentin, lamotrigine, felbamate, topiramate and fosphenytoin. American Family Physician 1998; 57: 513-520.
10. Frank, L. M., Enlow, T., Holmes, G. L., Manasco, P., Concannon, S., Chen, C., Womble, G. and Casale, E. J. Lamictal (lamotrigine) monotherapy for typical absence seizures in children. Epilepsia 1999; 40: 973-979.
11. Ritter, F., Glauser, T. A., Elterman, R. D. and Wyllie, E. Effectiveness, tolerability, and safety of topiramate in children with partial-onset seizures. Topiramate YP study group. Epilepsia 2000; 41 (Suppl. 1): S82-S85.
12. Reife, R., Pledger, G. and Wu, S. C. Topiramate as add-on therapy: pooled analysis of randomized controlled trials. Epilepsia 2000; 41 (Suppl. 1): S66-S71.
13. Montouris, G. D., Biton, V. and Rosenfeld, W. E. Nonfocal generalized tonic-clonic seizures: response during long-term topiramate treatment. Topiramate YTC/YTCE study group. Epilepsia 2000; 41 (Suppl. 1): S77-S81.
14. Glauser, T. A. Topiramate use in pediatric patients. Canadian Journal of Neurological Sciences 1998; 25: S8-S12.
15. Sachdeo, R. C., Glauser, T. A., Ritter, F., Reife, R., Lim, P. and Pledger, G. A double-blind, randomized trial of topiramate in Lennox-Gastaut syndrome. Neurology 1999; 52: 1882-1887.
16. Glauser, T. A. Topiramate. Epilepsia 1999; 40 (Suppl. 5): S71-S80.
17. Blomquist, H. K. and Zetterlund, B. Evaluation of treatment in typical absence seizures. The roles of long-term EEG monitoring and ethosuximide. Acta Paediatrica Scandinavica 1985; 74: 409-415.
18. Browne, T. R., Dreifuss, F. E., Penry, J. K., Porter, R. J. and White, B. G. Clinical and EEG estimates of absence seizure frequency. Archives of Neurology 1983; 40: 469-472.
19. Loiseau, P. Childhood absence epilepsy. In: Epileptic Syndromes in Infancy, Childhood and Adolescence (Eds J. Roger, M. Bureau, C. Dravet, F. E. Dreiffus, A. Perret and P. Wolf). London, Libbey, 1992: pp. 135-151.
20. Reife, R. Topiramate: a novel antiepileptic agent. In: Treatment of Epilepsy (Eds S. Shorvon, F. Dreifuss, D. Fish and D. Thomas). Oxford, Blackwell Science, 1996: pp. 471-481.